Published in J Clin Microbiol on December 01, 1996
Carbapenemases: the versatile beta-lactamases. Clin Microbiol Rev (2007) 15.82
Metallo-beta-lactamases: the quiet before the storm? Clin Microbiol Rev (2005) 12.07
Cloning and characterization of blaVIM, a new integron-borne metallo-beta-lactamase gene from a Pseudomonas aeruginosa clinical isolate. Antimicrob Agents Chemother (1999) 9.01
Outbreak of Klebsiella pneumoniae producing a new carbapenem-hydrolyzing class A beta-lactamase, KPC-3, in a New York Medical Center. Antimicrob Agents Chemother (2004) 7.99
Convenient test for screening metallo-beta-lactamase-producing gram-negative bacteria by using thiol compounds. J Clin Microbiol (2000) 5.69
Carbapenemases in Klebsiella pneumoniae and other Enterobacteriaceae: an evolving crisis of global dimensions. Clin Microbiol Rev (2012) 5.65
Metallo-beta-lactamases in clinical Pseudomonas isolates in Taiwan and identification of VIM-3, a novel variant of the VIM-2 enzyme. Antimicrob Agents Chemother (2001) 4.72
Outbreak of infections caused by Pseudomonas aeruginosa producing VIM-1 carbapenemase in Greece. J Clin Microbiol (2000) 4.67
Structure of In31, a blaIMP-containing Pseudomonas aeruginosa integron phyletically related to In5, which carries an unusual array of gene cassettes. Antimicrob Agents Chemother (1999) 4.24
Imipenem-EDTA disk method for differentiation of metallo-beta-lactamase-producing clinical isolates of Pseudomonas spp. and Acinetobacter spp. J Clin Microbiol (2002) 4.15
IMP-4, a novel metallo-beta-lactamase from nosocomial Acinetobacter spp. collected in Hong Kong between 1994 and 1998. Antimicrob Agents Chemother (2001) 3.80
Rapid detection and evaluation of clinical characteristics of emerging multiple-drug-resistant gram-negative rods carrying the metallo-beta-lactamase gene blaIMP. Antimicrob Agents Chemother (1998) 3.57
Integrons and gene cassettes in the enterobacteriaceae. Antimicrob Agents Chemother (2001) 3.45
Evaluation of a new Etest for detecting metallo-beta-lactamases in routine clinical testing. J Clin Microbiol (2002) 3.38
Amino acid substitutions in a variant of IMP-1 metallo-beta-lactamase. Antimicrob Agents Chemother (2000) 3.03
OXA-28, an extended-spectrum variant of OXA-10 beta-lactamase from Pseudomonas aeruginosa and its plasmid- and integron-located gene. Antimicrob Agents Chemother (2001) 3.00
VIM-1 Metallo-beta-lactamase-producing Klebsiella pneumoniae strains in Greek hospitals. J Clin Microbiol (2003) 2.98
Nosocomial outbreak of carbapenem-resistant Pseudomonas aeruginosa with a new bla(IMP) allele, bla(IMP-7). Antimicrob Agents Chemother (2002) 2.97
Phenotypic detection of carbapenem-susceptible metallo-beta-lactamase-producing gram-negative bacilli in the clinical laboratory. J Clin Microbiol (2006) 2.89
Detection of Pseudomonas aeruginosa producing metallo-beta-lactamases in a large centralized laboratory. J Clin Microbiol (2005) 2.89
Characterization and sequence of the Chryseobacterium (Flavobacterium) meningosepticum carbapenemase: a new molecular class B beta-lactamase showing a broad substrate profile. Biochem J (1998) 2.78
Identification of epidemic strains of Acinetobacter baumannii by integrase gene PCR. J Clin Microbiol (2001) 2.66
Outbreak of carbapenem-resistant Acinetobacter baumannii producing the OXA-23 enzyme in Curitiba, Brazil. J Clin Microbiol (2003) 2.55
Molecular and biochemical heterogeneity of class B carbapenem-hydrolyzing beta-lactamases in Chryseobacterium meningosepticum. Antimicrob Agents Chemother (2000) 2.49
PCR typing of genetic determinants for metallo-beta-lactamases and integrases carried by gram-negative bacteria isolated in Japan, with focus on the class 3 integron. J Clin Microbiol (2003) 2.35
Molecular detection of antimicrobial resistance. Clin Microbiol Rev (2001) 2.31
Comparison of BD Phoenix, Vitek 2, and MicroScan automated systems for detection and inference of mechanisms responsible for carbapenem resistance in Enterobacteriaceae. J Clin Microbiol (2010) 2.30
Identification of a plasmid encoding SHV-12, TEM-1, and a variant of IMP-2 metallo-beta-lactamase, IMP-8, from a clinical isolate of Klebsiella pneumoniae. Antimicrob Agents Chemother (2001) 2.21
Comparison of a novel, rapid chromogenic biochemical assay, the Carba NP test, with the modified Hodge test for detection of carbapenemase-producing Gram-negative bacilli. J Clin Microbiol (2013) 2.09
Purification and biochemical characterization of the VIM-1 metallo-beta-lactamase. Antimicrob Agents Chemother (2000) 2.08
Nosocomial infections caused by multidrug-resistant isolates of pseudomonas putida producing VIM-1 metallo-beta-lactamase. J Clin Microbiol (2002) 2.02
Outbreaks in distinct regions due to a single Klebsiella pneumoniae clone carrying a bla VIM-1 metallo-{beta}-lactamase gene. J Clin Microbiol (2005) 1.96
Outbreak of infection with multidrug-resistant Klebsiella pneumoniae carrying bla(IMP-8) in a university medical center in Taiwan. J Clin Microbiol (2001) 1.88
Beta-lactam antibiotics: from antibiosis to resistance and bacteriology. APMIS (2010) 1.78
Horizontal gene transfer in a polyclonal outbreak of carbapenem-resistant Acinetobacter baumannii. J Clin Microbiol (2006) 1.71
Carbapenemases of Chryseobacterium (Flavobacterium) meningosepticum: distribution of blaB and characterization of a novel metallo-beta-lactamase gene, blaB3, in the type strain, NCTC 10016. Antimicrob Agents Chemother (2000) 1.68
Endemic carbapenem resistance associated with OXA-40 carbapenemase among Acinetobacter baumannii isolates from a hospital in northern Spain. J Clin Microbiol (2002) 1.67
Nosocomial spread of ceftazidime-resistant Klebsiella pneumoniae strains producing a novel class a beta-lactamase, GES-3, in a neonatal intensive care unit in Japan. Antimicrob Agents Chemother (2004) 1.65
Outbreak of carbapenem-resistant Acinetobacter baumannii producing the carbapenemase OXA-23 in a tertiary care hospital of Papeete, French Polynesia. J Clin Microbiol (2005) 1.64
Molecular analysis of metallo-beta-lactamase gene bla(SPM-1)-surrounding sequences from disseminated Pseudomonas aeruginosa isolates in Recife, Brazil. Antimicrob Agents Chemother (2004) 1.60
Metallo-beta-lactamase producers in environmental microbiota: new molecular class B enzyme in Janthinobacterium lividum. Antimicrob Agents Chemother (2001) 1.57
Characterization of a novel plasmid-mediated cephalosporinase (CMY-9) and its genetic environment in an Escherichia coli clinical isolate. Antimicrob Agents Chemother (2002) 1.43
First isolation of metallo-beta-lactamase-producing multiresistant Klebsiella pneumoniae from a patient in Brazil. J Clin Microbiol (2005) 1.41
Antimicrobial susceptibility testing of carbapenems: multicenter validity testing and accuracy levels of five antimicrobial test methods for detecting resistance in Enterobacteriaceae and Pseudomonas aeruginosa isolates. J Clin Microbiol (2003) 1.35
Molecular characterization of a new class 3 integron in Klebsiella pneumoniae. Antimicrob Agents Chemother (2003) 1.33
Endemic carbapenem-resistant Pseudomonas aeruginosa with acquired metallo-beta-lactamase determinants in European hospital. Emerg Infect Dis (2004) 1.27
The T7-related Pseudomonas putida phage φ15 displays virion-associated biofilm degradation properties. PLoS One (2011) 1.25
Metallo-beta-lactamase-producing gram-negative bacilli: laboratory-based surveillance in cooperation with 13 clinical laboratories in the Kinki region of Japan. J Clin Microbiol (2004) 1.25
Spread of integron-associated VIM-type metallo-beta-lactamase genes among imipenem-nonsusceptible Pseudomonas aeruginosa strains in Greek hospitals. J Clin Microbiol (2003) 1.24
Genetic and biochemical characterization of a novel metallo-β-lactamase, TMB-1, from an Achromobacter xylosoxidans strain isolated in Tripoli, Libya. Antimicrob Agents Chemother (2012) 1.24
Detection of a variant metallo-beta-lactamase, IMP-10, from two unrelated strains of Pseudomonas aeruginosa and an alcaligenes xylosoxidans strain. Antimicrob Agents Chemother (2002) 1.22
First isolation of blaVIM-2 in an environmental isolate of Pseudomonas pseudoalcaligenes. Antimicrob Agents Chemother (2005) 1.20
Emergence of multidrug-resistant Klebsiella pneumoniae isolates producing VIM-4 metallo-beta-lactamase, CTX-M-15 extended-spectrum beta-lactamase, and CMY-4 AmpC beta-lactamase in a Tunisian university hospital. Antimicrob Agents Chemother (2006) 1.19
VIM-1 metallo-beta-lactamase in Acinetobacter baumannii. Emerg Infect Dis (2006) 1.18
Characterization of In100, a new integron carrying a metallo-{beta}-lactamase and a carbenicillinase, from Pseudomonas aeruginosa. Antimicrob Agents Chemother (2005) 1.17
Multiniche screening reveals the clinically relevant metallo-beta-lactamase VIM-2 in Pseudomonas aeruginosa far from the hospital setting: an ongoing dispersion process? Appl Environ Microbiol (2006) 1.15
Evolving carbapenemases: can medicinal chemists advance one step ahead of the coming storm? J Med Chem (2010) 1.09
Genetic and biochemical characterization of an acquired subgroup B3 metallo-β-lactamase gene, blaAIM-1, and its unique genetic context in Pseudomonas aeruginosa from Australia. Antimicrob Agents Chemother (2012) 1.08
VIM-2-producing Pseudomonas putida, Buenos Aires. Emerg Infect Dis (2007) 1.06
Carbapenem-resistant Pseudomonas aeruginosa in malaysia producing IMP-7 beta-lactamase. Antimicrob Agents Chemother (2002) 1.06
Carbapenem derivatives as potential inhibitors of various beta-lactamases, including class B metallo-beta-lactamases. Antimicrob Agents Chemother (1999) 1.05
Presence of Pseudomonas putida strains harboring plasmids bearing the metallo-beta-lactamase gene bla(IMP) in a hospital in Japan. J Clin Microbiol (2003) 1.05
First occurrence of an IMP metallo-beta-lactamase in Aeromonas caviae: IMP-19 in an isolate from France. Antimicrob Agents Chemother (2007) 1.03
Molecular characterization of class 3 integrons from Delftia spp. J Bacteriol (2007) 1.01
Role of a solvent-exposed tryptophan in the recognition and binding of antibiotic substrates for a metallo-beta-lactamase. Protein Sci (2003) 1.01
Evaluation of phenotypic tests for detection of metallo-beta-lactamase-producing Pseudomonas aeruginosa strains in China. J Clin Microbiol (2009) 1.01
Characterization of a naturally occurring class D beta-lactamase from Achromobacter xylosoxidans. Antimicrob Agents Chemother (2008) 1.01
Mutational analysis of the two zinc-binding sites of the Bacillus cereus 569/H/9 metallo-beta-lactamase. Biochem J (2002) 1.00
Outbreak of infection by carbapenem-resistant Acinetobacter baumannii producing the carbapenemase OXA-58 in Belgium. J Clin Microbiol (2006) 1.00
Efficacies of imipenem, meropenem, cefepime, and ceftazidime in rats with experimental pneumonia due to a carbapenem-hydrolyzing beta-lactamase-producing strain of Enterobacter cloacae. Antimicrob Agents Chemother (2000) 0.99
Class 1 integron in staphylococci. Mol Biol Rep (2011) 0.98
Rapid and direct real-time detection of blaKPC and blaNDM from surveillance samples. J Clin Microbiol (2013) 0.98
Functional analysis of the active site of a metallo-beta-lactamase proliferating in Japan. Antimicrob Agents Chemother (2000) 0.97
bla(IMP-9) and its association with large plasmids carried by Pseudomonas aeruginosa isolates from the People's Republic of China. Antimicrob Agents Chemother (2006) 0.95
Metallo-beta-lactamase or extended-spectrum beta-lactamase: a wolf in sheep's clothing. J Clin Microbiol (2007) 0.95
Clonal spread of IMP-1-producing Pseudomonas aeruginosa in two hospitals in Singapore. J Clin Microbiol (2004) 0.93
Molecular dynamic simulations of the metallo-beta-lactamase from Bacteroides fragilis in the presence and absence of a tight-binding inhibitor. J Mol Model (2008) 0.92
VIM-2 metallo-beta-lactamase in Achromobacter xylosoxidans in Europe. Eur J Clin Microbiol Infect Dis (2005) 0.91
Identification of a series of tricyclic natural products as potent broad-spectrum inhibitors of metallo-beta-lactamases. Antimicrob Agents Chemother (2002) 0.91
Trends in antimicrobial-drug resistance in Japan. Emerg Infect Dis (2001) 0.91
Resistance integrons: class 1, 2 and 3 integrons. Ann Clin Microbiol Antimicrob (2015) 0.91
In vivo folding of recombinant metallo-beta-lactamase L1 requires the presence of Zn(II). Protein Sci (2004) 0.90
Successive emergence of extended-spectrum beta-lactamase-producing and carbapenemase-producing Enterobacter aerogenes isolates in a university hospital. J Clin Microbiol (2008) 0.87
Characterization of pKP-M1144, a Novel ColE1-Like Plasmid Encoding IMP-8, GES-5, and BEL-1 β-Lactamases, from a Klebsiella pneumoniae Sequence Type 252 Isolate. Antimicrob Agents Chemother (2015) 0.85
Integrons containing the VIM-2 metallo-beta-lactamase gene among imipenem-resistant Pseudomonas aeruginosa strains from different Chinese hospitals. J Clin Microbiol (2006) 0.84
Pseudo-outbreak of imipenem-resistant Acinetobacter baumannii resulting from false susceptibility testing by a rapid automated system. J Clin Microbiol (2000) 0.84
Identification of bla KPC-2 on different plasmids of three Morganella morganii isolates. Eur J Clin Microbiol Infect Dis (2011) 0.84
Antibiotic Resistance Pattern and Evaluation of Metallo-Beta Lactamase Genes Including bla- IMP and bla- VIM Types in Pseudomonas aeruginosa Isolated from Patients in Tehran Hospitals. ISRN Microbiol (2014) 0.84
Genetic acquisition of NDM gene offers sustainability among clinical isolates of Pseudomonas aeruginosa in clinical settings. PLoS One (2015) 0.82
B1-Metallo-β-Lactamases: Where Do We Stand? Curr Drug Targets (2016) 0.82
Carbapenemase-producing Enterobacteriaceae recovered from the environment of a swine farrow-to-finish operation in the United States. Antimicrob Agents Chemother (2016) 0.80
Biochemical characterization of IMP-30, a metallo-β-lactamase with enhanced activity toward ceftazidime. Antimicrob Agents Chemother (2013) 0.79
Genetic Environment of Plasmid Mediated CTX-M-15 Extended Spectrum Beta-Lactamases from Clinical and Food Borne Bacteria in North-Eastern India. PLoS One (2015) 0.77
Isolation of the first IMP-4 metallo-β-lactamase producing Klebsiella pneumoniae in Tianjin, China. Braz J Microbiol (2012) 0.76
Hypermutable Pseudomonas aeruginosa in Cystic fibrosis patients from two Brazilian cities. J Clin Microbiol (2013) 0.75
Whole-Genome Sequencing and Comparative Analysis of Mycobacterium brisbanense Reveals a Possible Soil Origin and Capability in Fertiliser Synthesis. PLoS One (2016) 0.75
AMINOGLYCOSIDE RESISTANCE GENES IN Pseudomonas aeruginosa ISOLATES FROM CUMANA, VENEZUELA. Rev Inst Med Trop Sao Paulo (2016) 0.75
Supplementation of growth media with Zn2+ facilitates detection of VIM-2-producing Pseudomonas aeruginosa. J Clin Microbiol (2008) 0.75
Carbapenem- and Colistin-Resistant Enterobacter cloacae from Delta, Colorado, in 2015. Antimicrob Agents Chemother (2016) 0.75
Detection of Integrons from Escherichia coli Isolates Obtained from Some Selected Animals in Republic of Korea. Indian J Microbiol (2011) 0.75
PCR mapping of integrons reveals several novel combinations of resistance genes. Antimicrob Agents Chemother (1995) 12.54
More extended-spectrum beta-lactamases. Antimicrob Agents Chemother (1991) 11.28
Gene cassettes: a new class of mobile element. Microbiology (1995) 9.79
Molecular characterization of an enterobacterial metallo beta-lactamase found in a clinical isolate of Serratia marcescens that shows imipenem resistance. Antimicrob Agents Chemother (1994) 8.64
Transferable imipenem resistance in Pseudomonas aeruginosa. Antimicrob Agents Chemother (1991) 7.10
A novel integron-like element carrying the metallo-beta-lactamase gene blaIMP. Antimicrob Agents Chemother (1995) 6.00
Site-specific insertion of genes into integrons: role of the 59-base element and determination of the recombination cross-over point. Mol Microbiol (1991) 5.97
Multifocal outbreaks of metallo-beta-lactamase-producing Pseudomonas aeruginosa resistant to broad-spectrum beta-lactams, including carbapenems. Antimicrob Agents Chemother (1996) 5.36
Plasmid-mediated dissemination of the metallo-beta-lactamase gene blaIMP among clinically isolated strains of Serratia marcescens. Antimicrob Agents Chemother (1995) 4.71
Construction and expression of hybrid plasmids containing the Escherichia coli glyA genes. Gene (1981) 3.57
Purification and characterization of metallo-beta-lactamase from Serratia marcescens. Microbiol Immunol (1995) 2.06
In vitro activity of a new carbapenem antibiotic, BO-2727, with potent antipseudomonal activity. Antimicrob Agents Chemother (1993) 1.85
Cloning and expression in Enterobacteriaceae of the extended-spectrum beta-lactamase gene from a Pseudomonas aeruginosa plasmid. FEMS Microbiol Lett (1994) 1.83
Effect of pH on activities of novel beta-lactamases and beta-lactamase inhibitors against these beta-lactamases. Antimicrob Agents Chemother (1995) 1.46
Transformation of intact yeast cells treated with alkali cations. J Bacteriol (1983) 100.26
Generation of influenza A viruses entirely from cloned cDNAs. Proc Natl Acad Sci U S A (1999) 14.90
Molecular characterization of an enterobacterial metallo beta-lactamase found in a clinical isolate of Serratia marcescens that shows imipenem resistance. Antimicrob Agents Chemother (1994) 8.64
THE ETIOLOGY, MODE OF INFECTION, AND SPECIFIC THERAPY OF WEIL'S DISEASE (SPIROCHAETOSIS ICTEROHAEMORRHAGICA). J Exp Med (1916) 8.21
Gene mapping of the putative structural region of the hepatitis C virus genome by in vitro processing analysis. Proc Natl Acad Sci U S A (1991) 7.15
Solid phase synthesis of polynucleotides. VI. Further studies on polystyrene copolymers for the solid support. Nucleic Acids Res (1982) 6.38
A novel integron-like element carrying the metallo-beta-lactamase gene blaIMP. Antimicrob Agents Chemother (1995) 6.00
Chromosomal beta-lactamase of Klebsiella oxytoca, a new class A enzyme that hydrolyzes broad-spectrum beta-lactam antibiotics. Antimicrob Agents Chemother (1989) 5.98
Electric and magnetic stimulation of human motor cortex: surface EMG and single motor unit responses. J Physiol (1989) 5.69
Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells. Cell Death Differ (2004) 5.49
Two distinct proteinase activities required for the processing of a putative nonstructural precursor protein of hepatitis C virus. J Virol (1993) 5.41
Multifocal outbreaks of metallo-beta-lactamase-producing Pseudomonas aeruginosa resistant to broad-spectrum beta-lactams, including carbapenems. Antimicrob Agents Chemother (1996) 5.36
Close evolutionary relationship between the chromosomally encoded beta-lactamase gene of Klebsiella pneumoniae and the TEM beta-lactamase gene mediated by R plasmids. FEBS Lett (1986) 5.13
Arabidopsis ethylene-responsive element binding factors act as transcriptional activators or repressors of GCC box-mediated gene expression. Plant Cell (2000) 4.78
Plasmid-mediated dissemination of the metallo-beta-lactamase gene blaIMP among clinically isolated strains of Serratia marcescens. Antimicrob Agents Chemother (1995) 4.71
Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species. J Biol Chem (1999) 4.38
PI3K-Akt pathway: its functions and alterations in human cancer. Apoptosis (2004) 4.33
Genomic DNA fingerprinting by pulsed-field gel electrophoresis as an epidemiological marker for study of nosocomial infections caused by methicillin-resistant Staphylococcus aureus. J Clin Microbiol (1991) 4.33
THE PROPHYLAXIS OF WEIL'S DISEASE (SPIROCHAETOSIS ICTEROHAEMORRHAGICA). J Exp Med (1916) 4.33
Endovascular stent-graft placement for the treatment of acute aortic dissection. N Engl J Med (1999) 4.33
Two stage genome-wide search in inflammatory bowel disease provides evidence for susceptibility loci on chromosomes 3, 7 and 12. Nat Genet (1996) 4.09
Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity. Nature (1988) 3.99
THE RAT AS A CARRIER OF SPIROCHAETA ICTEROHAEMORRHAGIAE, THE CAUSATIVE AGENT OF WEIL'S DISEASE (SPIROCHAETOSIS ICTEROHAEMORRHAGICA). J Exp Med (1917) 3.80
Proteolytic processing and membrane association of putative nonstructural proteins of hepatitis C virus. Proc Natl Acad Sci U S A (1993) 3.68
Cloning and expression in Escherichia coli of the gene for human tumour necrosis factor. Nature (1985) 3.59
Cross-contamination potential with dental equipment. Lancet (1992) 3.55
Application of typing by pulsed-field gel electrophoresis to the study of Clostridium difficile in a neonatal intensive care unit. J Clin Microbiol (1994) 3.51
Histologic improvement of fibrosis in patients with hepatitis C who have sustained response to interferon therapy. Ann Intern Med (2000) 3.44
Structure of the 3' terminus of the hepatitis C virus genome. J Virol (1996) 3.40
Identification of toxin A-negative, toxin B-positive Clostridium difficile by PCR. J Clin Microbiol (1998) 3.34
Polymorphisms of UDP-glucuronosyltransferase gene and irinotecan toxicity: a pharmacogenetic analysis. Cancer Res (2000) 3.32
THE SERUM TREATMENT OF WEIL'S DISEASE (SPIROCHAETOSIS ICTEROHAEMORRHAGICA). J Exp Med (1916) 3.24
Plasmid-mediated AmpC-type beta-lactamase isolated from Klebsiella pneumoniae confers resistance to broad-spectrum beta-lactams, including moxalactam. Antimicrob Agents Chemother (1993) 3.19
Molecular epidemiologic evidence for association of thermostable direct hemolysin (TDH) and TDH-related hemolysin of Vibrio parahaemolyticus with gastroenteritis. Infect Immun (1990) 3.17
Programmed cell death, mitochondria and the plant hypersensitive response. Nature (2001) 3.16
Hypervariable regions in the putative glycoprotein of hepatitis C virus. Biochem Biophys Res Commun (1991) 3.09
Characterization of a plasmid-borne and constitutively expressed blaMOX-1 gene encoding AmpC-type beta-lactamase. Gene (1994) 3.08
IL-6 is required for the development of Th1 cell-mediated murine colitis. J Immunol (2000) 3.08
Chronic inflammatory polyradiculoneuropathy. Mayo Clin Proc (1975) 3.01
Rapid molecular genetic subtyping of serotype M1 group A Streptococcus strains. Emerg Infect Dis (1999) 2.96
Virulence for mice of Klebsiella strains belonging to the O1 group: relationship to their capsular (K) types. Infect Immun (1983) 2.93
Inhibition of uncoating of fowl plague virus by l-adamantanamine hydrochloride. Virology (1969) 2.91
Studies on the mass receptor potential of the isolated frog retina. II. On the basis of the ionic mechanism. Vision Res (1969) 2.91
DNA methylation is a critical cell-intrinsic determinant of astrocyte differentiation in the fetal brain. Dev Cell (2001) 2.90
Characteristic difference of hepatocellular carcinoma between hepatitis B- and C- viral infection in Japan. Hepatology (1995) 2.85
Major virulence factors, VacA and CagA, are commonly positive in Helicobacter pylori isolates in Japan. Gut (1998) 2.84
A preliminary survey of extended-spectrum beta-lactamases (ESBLs) in clinical isolates of Klebsiella pneumoniae and Escherichia coli in Japan. FEMS Microbiol Lett (2000) 2.75
Spread of drug-resistant Streptococcus pneumoniae in Asian countries: Asian Network for Surveillance of Resistant Pathogens (ANSORP) Study. Clin Infect Dis (1999) 2.74
Qualitative comparison of carbon dioxide-induced change in cerebral near-infrared spectroscopy versus jugular venous oxygen saturation in adults with acute brain disease. Crit Care Med (1995) 2.74
Nucleotide sequences of 4.5S RNAs associated with poly(A)-containing RNAs of mouse and hamster cells. Nucleic Acids Res (1980) 2.70
Effects of the complete removal of basic amino acid residues from the signal peptide on secretion of lipoprotein in Escherichia coli. J Biol Chem (1983) 2.66
Loss of all ndh genes as determined by sequencing the entire chloroplast genome of the black pine Pinus thunbergii. Proc Natl Acad Sci U S A (1994) 2.63
A novel sequence found at the 3' terminus of hepatitis C virus genome. Biochem Biophys Res Commun (1995) 2.58
Molecular cloning of hepatitis C virus genome from a single Japanese carrier: sequence variation within the same individual and among infected individuals. Virus Res (1992) 2.56
Characteristics of macrolide-resistant Mycoplasma pneumoniae strains isolated from patients and induced with erythromycin in vitro. Microbiol Immunol (2001) 2.52
Regulatory mechanisms in the pathways of cartilage and bone formation. Curr Opin Cell Biol (2001) 2.49
Mechanism of action of quinolones against Escherichia coli DNA gyrase. Antimicrob Agents Chemother (1993) 2.48
Genomic organization of the Klebsiella pneumoniae cps region responsible for serotype K2 capsular polysaccharide synthesis in the virulent strain Chedid. J Bacteriol (1995) 2.47
Fhit, a putative tumor suppressor in humans, is a dinucleoside 5',5"'-P1,P3-triphosphate hydrolase. Biochemistry (1996) 2.46
Inclusion of the transcervical approach in video-assisted thoracoscopic extended thymectomy (VATET) for myasthenia gravis: a prospective trial. Surg Endosc (2006) 2.39
Association of genetic variation in FTO with risk of obesity and type 2 diabetes with data from 96,551 East and South Asians. Diabetologia (2011) 2.37
The FHIT gene 3p14.2 is abnormal in lung cancer. Cell (1996) 2.36
Symbiotic utilization of polyvinyl alcohol by mixed cultures. Appl Environ Microbiol (1981) 2.36
Chlorophyll a oxygenase (CAO) is involved in chlorophyll b formation from chlorophyll a. Proc Natl Acad Sci U S A (1998) 2.35
Downregulation of beta1 integrins by Ebola virus glycoprotein: implication for virus entry. Virology (2000) 2.33
Mitochondrial dysfunction in bipolar disorder. Bipolar Disord (2000) 2.32
Hypoxia induces apoptosis with enhanced expression of Fas antigen messenger RNA in cultured neonatal rat cardiomyocytes. Circ Res (1994) 2.29
Defective mammopoiesis, but normal hematopoiesis, in mice with a targeted disruption of the prolactin gene. EMBO J (1997) 2.28