Published in J Alzheimers Dis on March 01, 2006
O-linked beta-N-acetylglucosamine (O-GlcNAc): Extensive crosstalk with phosphorylation to regulate signaling and transcription in response to nutrients and stress. Biochim Biophys Acta (2009) 2.64
Mechanisms of tau-induced neurodegeneration. Acta Neuropathol (2009) 2.27
Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets. Proc Natl Acad Sci U S A (2012) 1.75
Hyperphosphorylation of microtubule-associated protein tau: a promising therapeutic target for Alzheimer disease. Curr Med Chem (2008) 1.64
The role of tau in neurodegeneration. Mol Neurodegener (2009) 1.54
Presenilins are enriched in endoplasmic reticulum membranes associated with mitochondria. Am J Pathol (2009) 1.24
Decreased glucose transporters correlate to abnormal hyperphosphorylation of tau in Alzheimer disease. FEBS Lett (2008) 1.22
Dysregulation of insulin signaling, glucose transporters, O-GlcNAcylation, and phosphorylation of tau and neurofilaments in the brain: Implication for Alzheimer's disease. Am J Pathol (2009) 1.21
Tau and neurodegenerative disease: the story so far. Nat Rev Neurol (2015) 1.10
Successful therapies for Alzheimer's disease: why so many in animal models and none in humans? Front Pharmacol (2014) 1.10
Involvement of astroglial ceramide in palmitic acid-induced Alzheimer-like changes in primary neurons. Eur J Neurosci (2007) 1.06
Regulation between O-GlcNAcylation and phosphorylation of neurofilament-M and their dysregulation in Alzheimer disease. FASEB J (2007) 1.04
Brain glucose transporters, O-GlcNAcylation and phosphorylation of tau in diabetes and Alzheimer's disease. J Neurochem (2009) 1.03
Dysregulation of protein phosphorylation/dephosphorylation in Alzheimer's disease: a therapeutic target. J Biomed Biotechnol (2006) 0.96
Dysregulation of tau phosphorylation in mouse brain during excitotoxic damage. J Alzheimers Dis (2009) 0.92
The role of tau in Alzheimer's disease and related disorders. CNS Neurosci Ther (2010) 0.91
L-arginine and Alzheimer's disease. Int J Clin Exp Pathol (2008) 0.87
Metabolic Dysfunction of Astrocyte: An Initiating Factor in Beta-amyloid Pathology? Aging Neurodegener (2013) 0.86
Brain gene expression of a sporadic (icv-STZ Mouse) and a familial mouse model (3xTg-AD mouse) of Alzheimer's disease. PLoS One (2012) 0.86
Ceramides in Alzheimer's Disease: Key Mediators of Neuronal Apoptosis Induced by Oxidative Stress and Aβ Accumulation. Oxid Med Cell Longev (2015) 0.85
Insulin sensitizers improve learning and attenuate tau hyperphosphorylation and neuroinflammation in 3xTg-AD mice. J Neural Transm (Vienna) (2014) 0.81
Diverse regulation of AKT and GSK-3β by O-GlcNAcylation in various types of cells. FEBS Lett (2012) 0.81
Differential effects of simvastatin and pravastatin on expression of Alzheimer's disease-related genes in human astrocytes and neuronal cells. J Lipid Res (2009) 0.80
Alois Alzheimer revisited: differences in origin of the disease carrying his name. J Neural Transm (Vienna) (2006) 0.79
O-GlcNAcylation and neurodegeneration. Brain Res Bull (2016) 0.77
Insulin resistance: an emerging link in Alzheimer's disease. Neurol Sci (2013) 0.77
Interplay between protein glycosylation pathways in Alzheimer's disease. Sci Adv (2017) 0.75
The miRNA-processing enzyme dicer is essential for the morphogenesis and maintenance of hair follicles. Curr Biol (2006) 3.64
Transdifferentiation of glioblastoma cells into vascular endothelial cells. Proc Natl Acad Sci U S A (2011) 3.45
Tube Formation in Nanoscale Materials. Nanoscale Res Lett (2008) 2.83
The dragon strikes: lessons from the Wenchuan earthquake. Anesth Analg (2010) 2.78
O-GlcNAcylation regulates phosphorylation of tau: a mechanism involved in Alzheimer's disease. Proc Natl Acad Sci U S A (2004) 2.67
Application of hyperspectral imaging and chemometric calibrations for variety discrimination of maize seeds. Sensors (Basel) (2012) 2.46
Tau pathology in Alzheimer disease and other tauopathies. Biochim Biophys Acta (2005) 2.46
Magnetic resonance imaging of carotid atherosclerosis: plaque analysis. Top Magn Reson Imaging (2007) 2.36
Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation. Eur J Neurosci (2005) 2.35
Imaging dopamine transmission in cocaine dependence: link between neurochemistry and response to treatment. Am J Psychiatry (2011) 2.29
Mechanisms of tau-induced neurodegeneration. Acta Neuropathol (2009) 2.27
Kinases and phosphatases and tau sites involved in Alzheimer neurofibrillary degeneration. Eur J Neurosci (2007) 2.24
Activation of beta-catenin signaling programs embryonic epidermis to hair follicle fate. Development (2008) 1.96
CSF biomarker variability in the Alzheimer's Association quality control program. Alzheimers Dement (2013) 1.90
The Alzheimer's Association external quality control program for cerebrospinal fluid biomarkers. Alzheimers Dement (2011) 1.87
The genomics of selection in dogs and the parallel evolution between dogs and humans. Nat Commun (2013) 1.86
Labeling proteins with small molecules by site-specific posttranslational modification. J Am Chem Soc (2004) 1.84
Effect of rosuvastatin therapy on carotid plaque morphology and composition in moderately hypercholesterolemic patients: a high-resolution magnetic resonance imaging trial. Am Heart J (2008) 1.80
Microtubule-associated protein tau in development, degeneration and protection of neurons. Prog Neurobiol (2008) 1.74
GATA transcription factors integrate Wnt signalling during heart development. Development (2008) 1.74
A negative correlation between human carotid atherosclerotic plaque progression and plaque wall stress: in vivo MRI-based 2D/3D FSI models. J Biomech (2008) 1.74
MRI of atherosclerosis in clinical trials. NMR Biomed (2006) 1.71
Long-distance intercellular connectivity between cardiomyocytes and cardiofibroblasts mediated by membrane nanotubes. Cardiovasc Res (2011) 1.64
Up-regulation of phosphorylated/activated p70 S6 kinase and its relationship to neurofibrillary pathology in Alzheimer's disease. Am J Pathol (2003) 1.64
Truncation and activation of calcineurin A by calpain I in Alzheimer disease brain. J Biol Chem (2005) 1.64
Deficient brain insulin signalling pathway in Alzheimer's disease and diabetes. J Pathol (2011) 1.63
Promotion of hyperphosphorylation by frontotemporal dementia tau mutations. J Biol Chem (2004) 1.58
HTQC: a fast quality control toolkit for Illumina sequencing data. BMC Bioinformatics (2013) 1.58
Circadian clock protein cryptochrome regulates the expression of proinflammatory cytokines. Proc Natl Acad Sci U S A (2012) 1.57
Lower level of endogenous dopamine in patients with cocaine dependence: findings from PET imaging of D(2)/D(3) receptors following acute dopamine depletion. Am J Psychiatry (2009) 1.53
Unusual burns with combined injuries caused by mobile phone explosion: watch out for the "mini-bomb"! J Burn Care Res (2009) 1.53
The multiple roles for Sox2 in stem cell maintenance and tumorigenesis. Cell Signal (2013) 1.52
Reduced O-GlcNAcylation links lower brain glucose metabolism and tau pathology in Alzheimer's disease. Brain (2009) 1.48
Transcriptome profiling of early developing cotton fiber by deep-sequencing reveals significantly differential expression of genes in a fuzzless/lintless mutant. Genomics (2010) 1.48
Overexpression of Dyrk1A contributes to neurofibrillary degeneration in Down syndrome. FASEB J (2008) 1.43
Autophagy in stem cells. Autophagy (2013) 1.43
Abnormal hyperphosphorylation of tau: sites, regulation, and molecular mechanism of neurofibrillary degeneration. J Alzheimers Dis (2013) 1.40
Failure of neuronal maturation in Alzheimer disease dentate gyrus. J Neuropathol Exp Neurol (2008) 1.39
Echo rounds: intraoperative transesophageal echocardiography-guided patent ductus arteriosus ligation in an asymptomatic nonbacterial endocarditis patient. Anesth Analg (2010) 1.38
Up-regulation of inhibitors of protein phosphatase-2A in Alzheimer's disease. Am J Pathol (2005) 1.37
Site-specific effects of tau phosphorylation on its microtubule assembly activity and self-aggregation. Eur J Neurosci (2007) 1.36
NF-κB inhibits osteogenic differentiation of mesenchymal stem cells by promoting β-catenin degradation. Proc Natl Acad Sci U S A (2013) 1.35
Polymerization of hyperphosphorylated tau into filaments eliminates its inhibitory activity. Proc Natl Acad Sci U S A (2006) 1.33
Detection of intracellular cytokines by flow cytometry. Curr Protoc Immunol (2007) 1.32
Decreased dietary fiber intake and structural alteration of gut microbiota in patients with advanced colorectal adenoma. Am J Clin Nutr (2013) 1.29
The 3'-flap pocket of human flap endonuclease 1 is critical for substrate binding and catalysis. J Biol Chem (2009) 1.27
Up-regulation of mitogen-activated protein kinases ERK1/2 and MEK1/2 is associated with the progression of neurofibrillary degeneration in Alzheimer's disease. Brain Res Mol Brain Res (2002) 1.27
Involvement of aberrant glycosylation in phosphorylation of tau by cdk5 and GSK-3beta. FEBS Lett (2002) 1.26
p62/SQSTM1 involved in cisplatin resistance in human ovarian cancer cells by clearing ubiquitinated proteins. Eur J Cancer (2011) 1.25
A graphene oxide based immuno-biosensor for pathogen detection. Angew Chem Int Ed Engl (2010) 1.24
Mechanism of chronic aristolochic acid nephropathy: role of Smad3. Am J Physiol Renal Physiol (2010) 1.24
Activation of p53 promotes renal injury in acute aristolochic acid nephropathy. J Am Soc Nephrol (2009) 1.24
Tau becomes a more favorable substrate for GSK-3 when it is prephosphorylated by PKA in rat brain. J Biol Chem (2004) 1.24
Matrix stiffness reverses the effect of actomyosin tension on cell proliferation. J Cell Sci (2012) 1.23
Improved throughput traction microscopy reveals pivotal role for matrix stiffness in fibroblast contractility and TGF-β responsiveness. Am J Physiol Lung Cell Mol Physiol (2012) 1.22
Increased dosage of Dyrk1A alters alternative splicing factor (ASF)-regulated alternative splicing of tau in Down syndrome. J Biol Chem (2008) 1.22
Decreased glucose transporters correlate to abnormal hyperphosphorylation of tau in Alzheimer disease. FEBS Lett (2008) 1.22
Levels of nonphosphorylated and phosphorylated tau in cerebrospinal fluid of Alzheimer's disease patients : an ultrasensitive bienzyme-substrate-recycle enzyme-linked immunosorbent assay. Am J Pathol (2002) 1.22
Dysregulation of insulin signaling, glucose transporters, O-GlcNAcylation, and phosphorylation of tau and neurofilaments in the brain: Implication for Alzheimer's disease. Am J Pathol (2009) 1.21
A multiwell platform for studying stiffness-dependent cell biology. PLoS One (2011) 1.21
Rapamycin regulates Akt and ERK phosphorylation through mTORC1 and mTORC2 signaling pathways. Mol Carcinog (2010) 1.21
Trophic factors counteract elevated FGF-2-induced inhibition of adult neurogenesis. Neurobiol Aging (2006) 1.21
Localization of active forms of C-jun kinase (JNK) and p38 kinase in Alzheimer's disease brains at different stages of neurofibrillary degeneration. J Alzheimers Dis (2001) 1.20
Prevalence and Risk Factors for Latent Tuberculosis Infection among Health Care Workers in China: A Cross-Sectional Study. PLoS One (2013) 1.20
Role for the membrane receptor guanylyl cyclase-C in attention deficiency and hyperactive behavior. Science (2011) 1.19
Combined deletion of mouse dematin-headpiece and beta-adducin exerts a novel effect on the spectrin-actin junctions leading to erythrocyte fragility and hemolytic anemia. J Biol Chem (2006) 1.19
Small molecular compounds inhibit HIV-1 replication through specifically stabilizing APOBEC3G. J Biol Chem (2010) 1.18
Wnt/β-catenin signaling regulates postnatal development and regeneration of the salivary gland. Stem Cells Dev (2010) 1.17
The RNA helicase Mtr4p modulates polyadenylation in the TRAMP complex. Cell (2011) 1.17
Parameter estimation of dynamical systems via a chaotic ant swarm. Phys Rev E Stat Nonlin Soft Matter Phys (2010) 1.17
Rice seed cultivar identification using near-infrared hyperspectral imaging and multivariate data analysis. Sensors (Basel) (2013) 1.17
A combined fluorescence and microcomputed tomography system for small animal imaging. IEEE Trans Biomed Eng (2010) 1.17
Phosphorylation of tau at Thr212, Thr231, and Ser262 combined causes neurodegeneration. J Biol Chem (2010) 1.16