Published in Nat Biotechnol on April 23, 2006
The targeted delivery of multicomponent cargos to cancer cells by nanoporous particle-supported lipid bilayers. Nat Mater (2011) 2.84
Folic acid-mediated targeting of cowpea mosaic virus particles to tumor cells. Chem Biol (2007) 1.70
Computational model for nanocarrier binding to endothelium validated using in vivo, in vitro, and atomic force microscopy experiments. Proc Natl Acad Sci U S A (2010) 1.53
Polyvalent inhibitors of anthrax toxin that target host receptors. Proc Natl Acad Sci U S A (2006) 1.29
Polymer-Based Therapeutics. Macromolecules (2009) 1.04
Effects of Saccharide Spacing and Chain Extension on Toxin Inhibition by Glycopolypeptides of Well-Defined Architecture. Macromolecules (2007) 1.03
A viral nanoparticle with dual function as an anthrax antitoxin and vaccine. PLoS Pathog (2007) 1.02
Dynamic factors controlling targeting nanocarriers to vascular endothelium. Curr Drug Metab (2012) 1.02
Binding-site geometry and flexibility in DC-SIGN demonstrated with surface force measurements. Proc Natl Acad Sci U S A (2009) 0.97
Nanocarrier Hydrodynamics and Binding in Targeted Drug Delivery: Challenges in Numerical Modeling and Experimental Validation. J Nanotechnol Eng Med (2013) 0.95
Thermodynamics of multivalent interactions: influence of the linker. Langmuir (2010) 0.93
Bacteria clustering by polymers induces the expression of quorum-sensing-controlled phenotypes. Nat Chem (2013) 0.91
Synthetic allergen design reveals the significance of moderate affinity epitopes in mast cell degranulation. ACS Chem Biol (2012) 0.90
Quantitative glycomics from fluidic glycan microarrays. J Am Chem Soc (2009) 0.90
Multivalency-assisted control of intracellular signaling pathways: application for ubiquitin- dependent N-end rule pathway. Chem Biol (2009) 0.89
Structure-based design of a heptavalent anthrax toxin inhibitor. Biomacromolecules (2011) 0.85
Nanoscale patterning in mixed fluorocarbon-hydrocarbon phospholipid bilayers. J Am Chem Soc (2007) 0.85
Identification of exosite-targeting inhibitors of anthrax lethal factor by high-throughput screening. Chem Biol (2012) 0.83
Internal core protein cleavage leaves the hepatitis B virus capsid intact and enhances its capacity for surface display of heterologous whole chain proteins. J Biol Chem (2008) 0.82
Structure and thermotropic phase behavior of fluorinated phospholipid bilayers: a combined attenuated total reflection FTIR spectroscopy and imaging ellipsometry study. J Phys Chem B (2008) 0.81
Manipulation of electrostatic and saccharide linker interactions in the design of efficient glycopolypeptide-based cholera toxin inhibitors. Macromol Biosci (2010) 0.80
Designing inhibitors of anthrax toxin. Expert Opin Drug Discov (2014) 0.80
Obstructing toxin pathways by targeted pore blockage. Chem Rev (2012) 0.80
Stable and potent polyvalent anthrax toxin inhibitors: raft-inspired domain formation in liposomes that contain PEGylated lipids. Chemistry (2008) 0.78
Cationic PAMAM dendrimers as pore-blocking binary toxin inhibitors. Biomacromolecules (2014) 0.78
Anthrax toxin-induced rupture of artificial lipid bilayer membranes. J Chem Phys (2013) 0.78
Receptor-based identification of an inhibitory peptide against blood stage malaria. Biochem Biophys Res Commun (2008) 0.77
Design of monodisperse and well-defined polypeptide-based polyvalent inhibitors of anthrax toxin. Angew Chem Int Ed Engl (2014) 0.77
Validation of a Janus role of methotrexate-based PEGylated chitosan nanoparticles in vitro. Nanoscale Res Lett (2014) 0.76
Synthesis of Homopolymers and Copolymers Containing an Active Ester of Acrylic Acid by RAFT: Scaffolds for Controlling Polyvalent Ligand Display. J Polym Sci A Polym Chem (2008) 0.76
Defensive strategies of Bacillus anthracis that promote a fatal disease. Drug Discov Today Dis Mech (2007) 0.75
Inhibitors of the Metalloproteinase Anthrax Lethal Factor. Curr Top Med Chem (2016) 0.75
Antifouling coatings: recent developments in the design of surfaces that prevent fouling by proteins, bacteria, and marine organisms. Adv Mater (2010) 2.71
Mapping the lethal factor and edema factor binding sites on oligomeric anthrax protective antigen. Proc Natl Acad Sci U S A (2002) 2.51
Optogenetic protein clustering and signaling activation in mammalian cells. Nat Methods (2013) 2.22
The influence of hydrogel modulus on the proliferation and differentiation of encapsulated neural stem cells. Biomaterials (2009) 1.63
Structure and function of enzymes adsorbed onto single-walled carbon nanotubes. Langmuir (2004) 1.52
Binding of anthrax toxin to its receptor is similar to alpha integrin-ligand interactions. J Biol Chem (2003) 1.48
Tissue engineering--a shifting paradigm. Burns (2002) 1.38
2001: a year of major advances in anthrax toxin research. Trends Microbiol (2002) 1.32
Differentiation of human monocytic cell lines confers susceptibility to Bacillus anthracis lethal toxin. Cell Microbiol (2005) 1.29
Polyvalent inhibitors of anthrax toxin that target host receptors. Proc Natl Acad Sci U S A (2006) 1.29
Conformational differences between two amyloid β oligomers of similar size and dissimilar toxicity. J Biol Chem (2012) 1.26
Expression of Nlrp1b inflammasome components in human fibroblasts confers susceptibility to anthrax lethal toxin. Infect Immun (2009) 1.26
Capillarity-driven assembly of two-dimensional cellular carbon nanotube foams. Proc Natl Acad Sci U S A (2004) 1.26
The COMBREX project: design, methodology, and initial results. PLoS Biol (2013) 1.24
Effect of surface wettability on the adhesion of proteins. Langmuir (2004) 1.20
Cathepsin B-mediated autophagy flux facilitates the anthrax toxin receptor 2-mediated delivery of anthrax lethal factor into the cytoplasm. J Biol Chem (2009) 1.17
Protein-assisted solubilization of single-walled carbon nanotubes. Langmuir (2006) 1.14
Proteolytic processing of Nlrp1b is required for inflammasome activity. PLoS Pathog (2012) 1.14
Polyvalency: a promising strategy for drug design. Biotechnol Bioeng (2008) 1.13
Production and characterization of neutralizing monoclonal antibodies that recognize an epitope in domain 2 of Bacillus anthracis protective antigen. FEMS Immunol Med Microbiol (2006) 1.10
The cytoplasmic domain of anthrax toxin receptor 1 affects binding of the protective antigen. Infect Immun (2008) 1.09
Scaffolds based on degradable alginate hydrogels and poly(lactide-co-glycolide) microspheres for stem cell culture. Biomaterials (2007) 1.09
Engineering adeno-associated virus for one-step purification via immobilized metal affinity chromatography. Hum Gene Ther (2007) 1.08
Inhibition of mitogen-activated protein kinase signalling by Bacillus anthracis lethal toxin causes destabilization of interleukin-8 mRNA. Cell Microbiol (2006) 1.07
Pandemic and seasonal H1N1 influenza hemagglutinin-specific T cell responses elicited by seasonal influenza vaccination. Vaccine (2010) 1.07
The design of polyvalent scaffolds for targeted delivery. Adv Drug Deliv Rev (2009) 1.06
Parallel synthesis and screening of polymers for nonviral gene delivery. Mol Pharm (2009) 1.02
Insulin regulates the membrane arrival, fusion, and C-terminal unmasking of glucose transporter-4 via distinct phosphoinositides. J Biol Chem (2005) 1.01
Using bifunctional polymers presenting vancomycin and fluorescein groups to direct anti-fluorescein antibodies to self-assembled monolayers presenting d-alanine-d-alanine groups. J Am Chem Soc (2003) 1.01
Structure, function, and stability of enzymes covalently attached to single-walled carbon nanotubes. Langmuir (2007) 1.01
The design of polyvalent therapeutics. Chemistry (2008) 1.00
Nanoparticle-mediated cytoplasmic delivery of proteins to target cellular machinery. ACS Nano (2010) 0.98
Synthesis of copolymers containing an active ester of methacrylic acid by RAFT: controlled molecular weight scaffolds for biofunctionalization. Biomacromolecules (2006) 0.96
Synthesis of polyvalent inhibitors of controlled molecular weight: structure-activity relationship for inhibitors of anthrax toxin. Biomacromolecules (2006) 0.96
Multivalent ligands control stem cell behaviour in vitro and in vivo. Nat Nanotechnol (2013) 0.95
Functional characterization of peptide-based anthrax toxin inhibitors. Mol Pharm (2005) 0.95
The protein-nanomaterial interface. Curr Opin Biotechnol (2006) 0.93
Self-association of the transmembrane domain of an anthrax toxin receptor. J Mol Biol (2006) 0.92
Increasing protein stability through control of the nanoscale environment. Langmuir (2006) 0.92
Directed assembly of carbon nanotubes at liquid-liquid interfaces: nanoscale conveyors for interfacial biocatalysis. J Am Chem Soc (2006) 0.91
Water-soluble carbon nanotube-enzyme conjugates as functional biocatalytic formulations. Biotechnol Bioeng (2006) 0.91
Raftlike polyvalent inhibitors of the anthrax toxin: modulating inhibitory potency by formation of lipid microdomains. Angew Chem Int Ed Engl (2007) 0.90
Enhanced stability of enzymes adsorbed onto nanoparticles. J Nanosci Nanotechnol (2007) 0.90
Bacterial toxins can inhibit host cell autophagy through cAMP generation. Autophagy (2011) 0.90
Multivalency-assisted control of intracellular signaling pathways: application for ubiquitin- dependent N-end rule pathway. Chem Biol (2009) 0.89
Activation of the Nlrp1b inflammasome by reduction of cytosolic ATP. Infect Immun (2012) 0.89
Highly active and stable DNAzyme-carbon nanotube hybrids. J Am Chem Soc (2005) 0.89
Pathogenic serum amyloid A 1.1 shows a long oligomer-rich fibrillation lag phase contrary to the highly amyloidogenic non-pathogenic SAA2.2. J Biol Chem (2012) 0.89
Nanotube-assisted protein deactivation. Nat Nanotechnol (2007) 0.88
High-throughput screening of gene function in stem cells using clonal microarrays. Stem Cells (2007) 0.87
Recent advances in engineering polyvalent biological interactions. Biomacromolecules (2014) 0.86
Structure-based design of a heptavalent anthrax toxin inhibitor. Biomacromolecules (2011) 0.85
Inhibition of anthrax lethal toxin-induced cytolysis of RAW264.7 cells by celastrol. PLoS One (2008) 0.85
Sustained levels of FGF2 maintain undifferentiated stem cell cultures with biweekly feeding. PLoS One (2013) 0.85
Characterization of the oligomerization and aggregation of human Serum Amyloid A. PLoS One (2013) 0.84
Lysostaphin-functionalized cellulose fibers with antistaphylococcal activity for wound healing applications. Biomaterials (2011) 0.84
Carbon nanotube-induced loss of multicellular chirality on micropatterned substrate is mediated by oxidative stress. ACS Nano (2014) 0.84
The effect of long-term release of Shh from implanted biodegradable microspheres on recovery from spinal cord injury in mice. Biomaterials (2012) 0.83
Enzyme-driven Bacillus spore coat degradation leading to spore killing. Biotechnol Bioeng (2013) 0.83
Synthesis of potent inhibitors of anthrax toxin based on poly-L-glutamic acid. Bioconjug Chem (2006) 0.83
Light-inducible activation of target mRNA translation in mammalian cells. Chem Commun (Camb) (2013) 0.83
Direct interaction between anthrax toxin receptor 1 and the actin cytoskeleton. Biochemistry (2009) 0.83
Antistaphylococcal nanocomposite films based on enzyme-nanotube conjugates. ACS Nano (2010) 0.83
Regulation of stem cell signaling by nanoparticle-mediated intracellular protein delivery. Biomaterials (2011) 0.82
Design of water-soluble, thiol-reactive polymers of controlled molecular weight: a novel multivalent scaffold. Nanotechnology (2005) 0.82
Age-related changes in magnitude and diversity of cross-reactive CD4+ T-cell responses to the novel pandemic H1N1 influenza hemagglutinin. Hum Immunol (2010) 0.82
Enhancing protein stability by adsorption onto raftlike lipid domains. J Am Chem Soc (2009) 0.82
An anthrax lethal factor mutant that is defective at causing pyroptosis retains proapoptotic activity. FEBS J (2009) 0.81
Enzyme-based listericidal nanocomposites. Sci Rep (2013) 0.81
The effect of multivalent Sonic hedgehog on differentiation of human embryonic stem cells into dopaminergic and GABAergic neurons. Biomaterials (2013) 0.81
Surface plasmon resonance spectroscopy-based high-throughput screening of ligands for use in affinity and displacement chromatography. Langmuir (2008) 0.81
Polymer-nanotube-enzyme composites as active antifouling films. Small (2007) 0.81
Bidirectional regulation of mRNA translation in mammalian cells by using PUF domains. Angew Chem Int Ed Engl (2014) 0.80
Laccase- and chloroperoxidase-nanotube paint composites with bactericidal and sporicidal activity. Enzyme Microb Technol (2012) 0.80
Anthrax lethal toxin promotes dephosphorylation of TTP and formation of processing bodies. Cell Microbiol (2009) 0.80
Translational repression using BIV Tat peptide-TAR RNA interaction in mammalian cells. Chem Commun (Camb) (2013) 0.79
Characterization of the diffusion of epidermal growth factor receptor clusters by single particle tracking. Biochim Biophys Acta (2012) 0.79
Stable and potent polyvalent anthrax toxin inhibitors: raft-inspired domain formation in liposomes that contain PEGylated lipids. Chemistry (2008) 0.78
Microfluidic separation of DNA. Curr Opin Biotechnol (2003) 0.78
Thiol-mediated anchoring of ligands to self-assembled monolayers for studies of biospecific interactions. Langmuir (2006) 0.78