Increasing protein stability through control of the nanoscale environment.

PubWeight™: 0.92‹?›

🔗 View Article (PMID 16768515)

Published in Langmuir on June 20, 2006

Authors

Prashanth Asuri1, Sandeep S Karajanagi, Hoichang Yang, Tae-Jin Yim, Ravi S Kane, Jonathan S Dordick

Author Affiliations

1: Department of Chemical and Biological Engineering and Rensselaer Nanotechnology Center, Rensselaer Polytechnic Institute, Troy, New York 12180, USA.

Articles by these authors

Antifouling coatings: recent developments in the design of surfaces that prevent fouling by proteins, bacteria, and marine organisms. Adv Mater (2010) 2.71

Quantitative equivalence between polymer nanocomposites and thin polymer films. Nat Mater (2005) 2.27

Optogenetic protein clustering and signaling activation in mammalian cells. Nat Methods (2013) 2.22

Selective gas transport through few-layered graphene and graphene oxide membranes. Science (2013) 2.20

Radio-wave heating of iron oxide nanoparticles can regulate plasma glucose in mice. Science (2012) 2.14

Three-dimensional cellular microarray for high-throughput toxicology assays. Proc Natl Acad Sci U S A (2007) 2.09

Silica nanoparticle size influences the structure and enzymatic activity of adsorbed lysozyme. Langmuir (2004) 1.86

Nanowired three-dimensional cardiac patches. Nat Nanotechnol (2011) 1.76

E. coli K5 fermentation and the preparation of heparosan, a bioengineered heparin precursor. Biotechnol Bioeng (2010) 1.65

The influence of hydrogel modulus on the proliferation and differentiation of encapsulated neural stem cells. Biomaterials (2009) 1.63

High-throughput cellular microarray platforms: applications in drug discovery, toxicology and stem cell research. Trends Biotechnol (2009) 1.56

Structure and function of enzymes adsorbed onto single-walled carbon nanotubes. Langmuir (2004) 1.52

Inhibition of NADPH oxidase activation in endothelial cells by ortho-methoxy-substituted catechols. Endothelium (2002) 1.46

Ionic liquid-mediated selective extraction of lignin from wood leading to enhanced enzymatic cellulose hydrolysis. Biotechnol Bioeng (2009) 1.46

Resveratrol selectively remodels soluble oligomers and fibrils of amyloid Abeta into off-pathway conformers. J Biol Chem (2010) 1.35

Control of the heparosan N-deacetylation leads to an improved bioengineered heparin. Appl Microbiol Biotechnol (2011) 1.33

Statistical pattern matching facilitates the design of polyvalent inhibitors of anthrax and cholera toxins. Nat Biotechnol (2006) 1.32

Room temperature ionic liquids as emerging solvents for the pretreatment of lignocellulosic biomass. Biotechnol Bioeng (2011) 1.31

Analysis of E. coli K5 capsular polysaccharide heparosan. Anal Bioanal Chem (2010) 1.30

Polyvalent inhibitors of anthrax toxin that target host receptors. Proc Natl Acad Sci U S A (2006) 1.29

Ultra-performance ion-pairing liquid chromatography with on-line electrospray ion trap mass spectrometry for heparin disaccharide analysis. Anal Biochem (2011) 1.28

Unfolding of ribonuclease A on silica nanoparticle surfaces. Nano Lett (2007) 1.26

Conformational differences between two amyloid β oligomers of similar size and dissimilar toxicity. J Biol Chem (2012) 1.26

Capillarity-driven assembly of two-dimensional cellular carbon nanotube foams. Proc Natl Acad Sci U S A (2004) 1.26

Identification of a novel class in the alpha/beta hydrolase fold superfamily: the N-myc differentiation-related proteins. Proteins (2002) 1.25

Three-dimensional cell culture microarray for high-throughput studies of stem cell fate. Biotechnol Bioeng (2010) 1.22

Effect of surface wettability on the adhesion of proteins. Langmuir (2004) 1.20

Aromatic small molecules remodel toxic soluble oligomers of amyloid beta through three independent pathways. J Biol Chem (2010) 1.20

Enzyme activation for organic solvents made easy. Trends Biotechnol (2007) 1.19

Engineering of routes to heparin and related polysaccharides. Appl Microbiol Biotechnol (2011) 1.19

Protein-assisted solubilization of single-walled carbon nanotubes. Langmuir (2006) 1.14

Osmolyte trimethylamine-N-oxide does not affect the strength of hydrophobic interactions: origin of osmolyte compatibility. Biophys J (2005) 1.13

Metabolizing enzyme toxicology assay chip (MetaChip) for high-throughput microscale toxicity analyses. Proc Natl Acad Sci U S A (2005) 1.13

Polyvalency: a promising strategy for drug design. Biotechnol Bioeng (2008) 1.13

Recent progress and applications in glycosaminoglycan and heparin research. Curr Opin Chem Biol (2009) 1.10

Scaffolds based on degradable alginate hydrogels and poly(lactide-co-glycolide) microspheres for stem cell culture. Biomaterials (2007) 1.09

Effect of gold nanoparticle morphology on adsorbed protein structure and function. Biomaterials (2011) 1.08

Enzyme activation for nonaqueous media. Curr Opin Biotechnol (2002) 1.08

Engineering adeno-associated virus for one-step purification via immobilized metal affinity chromatography. Hum Gene Ther (2007) 1.08

Spaceflight promotes biofilm formation by Pseudomonas aeruginosa. PLoS One (2013) 1.08

Structural characterization of heparins from different commercial sources. Anal Bioanal Chem (2011) 1.07

On-chip, cell-based microarray immunofluorescence assay for high-throughput analysis of target proteins. Anal Chem (2008) 1.06

The design of polyvalent scaffolds for targeted delivery. Adv Drug Deliv Rev (2009) 1.06

Toward an artificial Golgi: redesigning the biological activities of heparan sulfate on a digital microfluidic chip. J Am Chem Soc (2009) 1.04

Glycosaminoglycans in infectious disease. Biol Rev Camb Philos Soc (2013) 1.04

Parallel synthesis and screening of polymers for nonviral gene delivery. Mol Pharm (2009) 1.02

Hydration of enzyme in nonaqueous media is consistent with solvent dependence of its activity. Biophys J (2004) 1.02

Blood compatible carbon nanotubes--nano-based neoproteoglycans. Langmuir (2006) 1.02

Using bifunctional polymers presenting vancomycin and fluorescein groups to direct anti-fluorescein antibodies to self-assembled monolayers presenting d-alanine-d-alanine groups. J Am Chem Soc (2003) 1.01

Enzymatic synthesis of dextran-containing hydrogels. Biomaterials (2002) 1.01

Structure, function, and stability of enzymes covalently attached to single-walled carbon nanotubes. Langmuir (2007) 1.01

The design of polyvalent therapeutics. Chemistry (2008) 1.00

Enzymatic synthesis of glycosaminoglycan heparin. Semin Thromb Hemost (2007) 1.00

Nanoparticle-mediated cytoplasmic delivery of proteins to target cellular machinery. ACS Nano (2010) 0.98

The role of the methoxyphenol apocynin, a vascular NADPH oxidase inhibitor, as a chemopreventative agent in the potential treatment of cardiovascular diseases. Curr Vasc Pharmacol (2008) 0.98

Escherichia coli K5 heparosan fermentation and improvement by genetic engineering. Bioeng Bugs (2011) 0.97

Synthesis of copolymers containing an active ester of methacrylic acid by RAFT: controlled molecular weight scaffolds for biofunctionalization. Biomacromolecules (2006) 0.96

Synthesis of polyvalent inhibitors of controlled molecular weight: structure-activity relationship for inhibitors of anthrax toxin. Biomacromolecules (2006) 0.96

Substrate profile analysis and ACP-mediated acyl transfer in Streptomyces coelicolor Type III polyketide synthases. Chembiochem (2007) 0.95

Multivalent ligands control stem cell behaviour in vitro and in vivo. Nat Nanotechnol (2013) 0.95

Functional characterization of peptide-based anthrax toxin inhibitors. Mol Pharm (2005) 0.95

Influence of a three-dimensional, microarray environment on human cell culture in drug screening systems. Biomaterials (2012) 0.95

Gene delivery in three-dimensional cell cultures by superparamagnetic nanoparticles. ACS Nano (2010) 0.93

Cu/Zn superoxide dismutase can form pore-like structures. Biochem Biophys Res Commun (2003) 0.93

High cell density cultivation of a recombinant E. coli strain expressing a key enzyme in bioengineered heparin production. Appl Microbiol Biotechnol (2013) 0.93

High-throughput human metabolism and toxicity analysis. Curr Opin Biotechnol (2006) 0.93

Cytochrome C on silica nanoparticles: influence of nanoparticle size on protein structure, stability, and activity. Small (2009) 0.93

Facile pretreatment of lignocellulosic biomass at high loadings in room temperature ionic liquids. Biotechnol Bioeng (2011) 0.93

The protein-nanomaterial interface. Curr Opin Biotechnol (2006) 0.93

Conductive cable fibers with insulating surface prepared by coaxial electrospinning of multiwalled nanotubes and cellulose. Biomacromolecules (2010) 0.92

High-throughput, microarray-based synthesis of natural product analogues via in vitro metabolic pathway construction. ACS Chem Biol (2007) 0.92

Water-soluble carbon nanotube-enzyme conjugates as functional biocatalytic formulations. Biotechnol Bioeng (2006) 0.91

Silicon atom substitution enhances interchain packing in a thiophene-based polymer system. Adv Mater (2010) 0.91

Directed assembly of carbon nanotubes at liquid-liquid interfaces: nanoscale conveyors for interfacial biocatalysis. J Am Chem Soc (2006) 0.91

Biocatalytic synthesis of highly ordered degradable dextran-based hydrogels. Biomaterials (2005) 0.91

Raftlike polyvalent inhibitors of the anthrax toxin: modulating inhibitory potency by formation of lipid microdomains. Angew Chem Int Ed Engl (2007) 0.90

Response surface optimization of the heparosan N-deacetylation in producing bioengineered heparin. J Biotechnol (2011) 0.90

Active-site motions and polarity enhance catalytic turnover of hydrated subtilisin dissolved in organic solvents. J Am Chem Soc (2009) 0.90

Enhanced stability of enzymes adsorbed onto nanoparticles. J Nanosci Nanotechnol (2007) 0.90

Highly active and stable DNAzyme-carbon nanotube hybrids. J Am Chem Soc (2005) 0.89

Multivalency-assisted control of intracellular signaling pathways: application for ubiquitin- dependent N-end rule pathway. Chem Biol (2009) 0.89

How interfaces affect hydrophobically driven polymer folding. J Phys Chem B (2009) 0.89

Recent advances in sulfotransferase enzyme activity assays. Anal Bioanal Chem (2012) 0.89

Biocompatibility of chemoenzymatically derived dextran-acrylate hydrogels. J Biomed Mater Res A (2004) 0.89

Pathogenic serum amyloid A 1.1 shows a long oligomer-rich fibrillation lag phase contrary to the highly amyloidogenic non-pathogenic SAA2.2. J Biol Chem (2012) 0.89

Inhibition of human vascular NADPH oxidase by apocynin derived oligophenols. Bioorg Med Chem (2009) 0.89

Nanotube-assisted protein deactivation. Nat Nanotechnol (2007) 0.88