Published in J Cell Sci on May 01, 2006
A systems view of epithelial-mesenchymal transition signaling states. Clin Exp Metastasis (2010) 1.95
Extracellular signal-regulated kinase/mitogen-activated protein kinase regulates actin organization and cell motility by phosphorylating the actin cross-linking protein EPLIN. Mol Cell Biol (2007) 1.17
Biology and therapeutic potential of cannabinoid CB2 receptor inverse agonists. Br J Pharmacol (2007) 1.15
Distinct microenvironmental cues stimulate divergent TLR4-mediated signaling pathways in macrophages. Sci Signal (2016) 1.05
The actin-bundling protein L-plastin: a critical regulator of immune cell function. Int J Cell Biol (2011) 1.03
Actin-bundling protein L-plastin regulates T cell activation. J Immunol (2010) 1.01
Plastin family of actin-bundling proteins: its functions in leukocytes, neurons, intestines, and cancer. Int J Cell Biol (2012) 0.96
Calcium binding is essential for plastin 3 function in Smn-deficient motoneurons. Hum Mol Genet (2013) 0.94
Priming of eosinophils by GM-CSF is mediated by protein kinase CbetaII-phosphorylated L-plastin. J Immunol (2011) 0.93
Quantitative kinetic study of the actin-bundling protein L-plastin and of its impact on actin turn-over. PLoS One (2010) 0.93
The actin-bundling protein L-plastin supports T-cell motility and activation. Immunol Rev (2013) 0.89
DNA promoter methylation-dependent transcription of the double C2-like domain β (DOC2B) gene regulates tumor growth in human cervical cancer. J Biol Chem (2014) 0.87
Proteome analysis of bronchoalveolar lavage in pulmonary langerhans cell histiocytosis. J Clin Bioinforma (2011) 0.87
Actin-bundling protein plastin 3 is a regulator of ectoplasmic specialization dynamics during spermatogenesis in the rat testis. FASEB J (2015) 0.85
Metastasis of prostate cancer and melanoma cells in a preclinical in vivo mouse model is enhanced by L-plastin expression and phosphorylation. Mol Cancer (2014) 0.84
L-plastin nanobodies perturb matrix degradation, podosome formation, stability and lifetime in THP-1 macrophages. PLoS One (2013) 0.83
Meta-analysis and profiling of cardiac expression modules. Physiol Genomics (2008) 0.82
The actin filament cross-linker L-plastin confers resistance to TNF-alpha in MCF-7 breast cancer cells in a phosphorylation-dependent manner. J Cell Mol Med (2009) 0.82
Characterization of the phosphoproteome in human bronchoalveolar lavage fluid. Int J Proteomics (2012) 0.81
Molecular mechanisms and functional implications of polarized actin remodeling at the T cell immunological synapse. Cell Mol Life Sci (2014) 0.79
Fascin Rigidity and L-plastin Flexibility Cooperate in Cancer Cell Invadopodia and Filopodia. J Biol Chem (2016) 0.78
Comparison of the neutrophil proteome in trauma patients and normal controls. Protein Pept Lett (2012) 0.78
Lecithin Prevents Cortical Cytoskeleton Reorganization in Rat Soleus Muscle Fibers under Short-Term Gravitational Disuse. PLoS One (2016) 0.77
Fimbrin phosphorylation by metaphase Cdk1 regulates actin cable dynamics in budding yeast. Nat Commun (2016) 0.76
Plastins regulate ectoplasmic specialization via its actin bundling activity on microfilaments in the rat testis. Asian J Androl (2016) 0.76
L-plastin is involved in NKG2D recruitment into lipid rafts and NKG2D-mediated NK cell migration. J Leukoc Biol (2014) 0.75
Proteomic and electron microscopy survey of large assemblies in macrophage cytoplasm. Mol Cell Proteomics (2011) 0.75
The Calcium-Dependent Switch Helix of L-Plastin Regulates Actin Bundling. Sci Rep (2017) 0.75
Mst1 Kinase Regulates the Actin-Bundling Protein L-Plastin To Promote T Cell Migration. J Immunol (2016) 0.75
miR-375 Regulates Invasion-Related Proteins Vimentin and L-Plastin. Am J Pathol (2017) 0.75
A recurrent de novo mutation in ACTG1 causes isolated ocular coloboma. Hum Mutat (2017) 0.75
Phosphoproteome and transcription factor activity profiling identify actions of the anti-inflammatory agent UTL-5g in LPS stimulated RAW 264.7 cells including disrupting actin remodeling and STAT-3 activation. Eur J Pharmacol (2017) 0.75
SIP1/ZEB2 induces EMT by repressing genes of different epithelial cell-cell junctions. Nucleic Acids Res (2005) 3.41
Disrupted function and axonal distribution of mutant tyrosyl-tRNA synthetase in dominant intermediate Charcot-Marie-Tooth neuropathy. Nat Genet (2006) 3.04
Mutant small heat-shock protein 27 causes axonal Charcot-Marie-Tooth disease and distal hereditary motor neuropathy. Nat Genet (2004) 3.00
Hot-spot residue in small heat-shock protein 22 causes distal motor neuropathy. Nat Genet (2004) 2.86
The transcription factor snail induces tumor cell invasion through modulation of the epithelial cell differentiation program. Cancer Res (2005) 2.74
Identification of a novel BBS gene (BBS12) highlights the major role of a vertebrate-specific branch of chaperonin-related proteins in Bardet-Biedl syndrome. Am J Hum Genet (2006) 2.44
YSK1 is activated by the Golgi matrix protein GM130 and plays a role in cell migration through its substrate 14-3-3zeta. J Cell Biol (2004) 2.29
Actin dynamics, architecture, and mechanics in cell motility. Physiol Rev (2014) 2.29
PIP(2)-PDZ domain binding controls the association of syntenin with the plasma membrane. Mol Cell (2002) 2.04
Tenascin-C and SF/HGF produced by myofibroblasts in vitro provide convergent pro-invasive signals to human colon cancer cells through RhoA and Rac. FASEB J (2004) 2.01
Stress release drives symmetry breaking for actin-based movement. Proc Natl Acad Sci U S A (2005) 1.75
Implication of the MAGI-1b/PTEN signalosome in stabilization of adherens junctions and suppression of invasiveness. FASEB J (2004) 1.61
Plastins: versatile modulators of actin organization in (patho)physiological cellular processes. Acta Pharmacol Sin (2005) 1.44
A novel network integrating a miRNA-203/SNAI1 feedback loop which regulates epithelial to mesenchymal transition. PLoS One (2012) 1.41
The c-kit tyrosine kinase inhibitor STI571 for colorectal cancer therapy. Cancer Res (2002) 1.36
Relaxing the actin cytoskeleton for adhesion and movement with Ena/VASP. J Cell Biol (2008) 1.34
Functional complexes between YAP2 and ZO-2 are PDZ domain-dependent, and regulate YAP2 nuclear localization and signalling. Biochem J (2010) 1.34
MIR@NT@N: a framework integrating transcription factors, microRNAs and their targets to identify sub-network motifs in a meta-regulation network model. BMC Bioinformatics (2011) 1.33
Gelsolin-induced epithelial cell invasion is dependent on Ras-Rac signaling. EMBO J (2002) 1.31
Transcriptional repression of microRNA genes by PML-RARA increases expression of key cancer proteins in acute promyelocytic leukemia. Blood (2008) 1.30
S32826, a nanomolar inhibitor of autotaxin: discovery, synthesis and applications as a pharmacological tool. J Pharmacol Exp Ther (2008) 1.28
Sequence and comparative genomic analysis of actin-related proteins. Mol Biol Cell (2005) 1.28
Implication of STAT3 signaling in human colonic cancer cells during intestinal trefoil factor 3 (TFF3) -- and vascular endothelial growth factor-mediated cellular invasion and tumor growth. Cancer Res (2005) 1.27
Membrane tension regulates motility by controlling lamellipodium organization. Proc Natl Acad Sci U S A (2011) 1.25
Critical role of N-cadherin in myofibroblast invasion and migration in vitro stimulated by colon-cancer-cell-derived TGF-beta or wounding. J Cell Sci (2004) 1.24
Upregulation of MMPs by soluble E-cadherin in human lung tumor cells. Int J Cancer (2003) 1.21
Activation of the FAK-src molecular scaffolds and p130Cas-JNK signaling cascades by alpha1-integrins during colon cancer cell invasion. Int J Oncol (2007) 1.16
Insulin-like growth factor-I receptor, E-cadherin and alpha v integrin form a dynamic complex under the control of alpha-catenin. Int J Cancer (2008) 1.15
Proinvasive activity of BMP-7 through SMAD4/src-independent and ERK/Rac/JNK-dependent signaling pathways in colon cancer cells. Cell Signal (2007) 1.13
Neurotensin receptor 1 gene activation by the Tcf/beta-catenin pathway is an early event in human colonic adenomas. Carcinogenesis (2005) 1.12
The actin cytoskeleton as a therapeutic target: state of the art and future directions. Prog Cell Cycle Res (2003) 1.11
Downregulation of gelsolin family proteins counteracts cancer cell invasion in vitro. Cancer Lett (2007) 1.11
Plasmin produces an E-cadherin fragment that stimulates cancer cell invasion. Biol Chem (2002) 1.09
Expression of neurotensin and NT1 receptor in human breast cancer: a potential role in tumor progression. Cancer Res (2006) 1.07
Disruption of STAT3 signaling leads to tumor cell invasion through alterations of homotypic cell-cell adhesion complexes. Oncogene (2004) 1.07
The proinvasive activity of Wnt-2 is mediated through a noncanonical Wnt pathway coupled to GSK-3beta and c-Jun/AP-1 signaling. FASEB J (2004) 1.06
Trefoil peptides as proangiogenic factors in vivo and in vitro: implication of cyclooxygenase-2 and EGF receptor signaling. FASEB J (2003) 1.06
TAZ interacts with zonula occludens-1 and -2 proteins in a PDZ-1 dependent manner. FEBS Lett (2010) 1.04
VASP governs actin dynamics by modulating filament anchoring. Biophys J (2006) 1.03
Anticancer activity of BIM-46174, a new inhibitor of the heterotrimeric Galpha/Gbetagamma protein complex. Cancer Res (2006) 1.03
Nuclear actin-binding proteins as modulators of gene transcription. Traffic (2005) 1.02
Increased monomerization of mutant HSPB1 leads to protein hyperactivity in Charcot-Marie-Tooth neuropathy. J Biol Chem (2010) 1.01
Trefoil factor family (TFF) peptides and cancer progression. Peptides (2004) 1.01
Requirement of both mucins and proteoglycans in cell-cell dissociation and invasiveness of colon carcinoma HT-29 cells. Int J Cancer (2003) 1.00
Actin-filament cross-linking protein T-plastin increases Arp2/3-mediated actin-based movement. J Cell Sci (2005) 1.00
In colon carcinogenesis, the cytoskeletal protein gelsolin is down-regulated during the transition from adenoma to carcinoma. Hum Pathol (2008) 0.99
Increased importin-beta-dependent nuclear import of the actin modulating protein CapG promotes cell invasion. J Cell Sci (2004) 0.99
Functional invalidation of the autotaxin gene by a single amino acid mutation in mouse is lethal. FEBS Lett (2007) 0.97
Synergistic cooperation between the AP-1 and LEF-1 transcription factors in activation of the matrilysin promoter by the src oncogene: implications in cellular invasion. FASEB J (2003) 0.97
Actin polymerization or myosin contraction: two ways to build up cortical tension for symmetry breaking. Philos Trans R Soc Lond B Biol Sci (2013) 0.97
TRIP6, a novel molecular partner of the MAGI-1 scaffolding molecule, promotes invasiveness. FASEB J (2008) 0.96
Quantitative kinetic study of the actin-bundling protein L-plastin and of its impact on actin turn-over. PLoS One (2010) 0.93
A nanobody targeting the F-actin capping protein CapG restrains breast cancer metastasis. Breast Cancer Res (2013) 0.93
The tandem PDZ domains of syntenin promote cell invasion. Exp Cell Res (2007) 0.93
RhoA- and RhoD-dependent regulatory switch of Galpha subunit signaling by PAR-1 receptors in cellular invasion. FASEB J (2002) 0.92
Inhibition of vascular endothelial growth factor (VEGF)-165 and semaphorin 3A-mediated cellular invasion and tumor growth by the VEGF signaling inhibitor ZD4190 in human colon cancer cells and xenografts. Mol Cancer Ther (2006) 0.92
The PDZ2 domain of zonula occludens-1 and -2 is a phosphoinositide binding domain. Cell Mol Life Sci (2009) 0.92
Nanobody-induced perturbation of LFA-1/L-plastin phosphorylation impairs MTOC docking, immune synapse formation and T cell activation. Cell Mol Life Sci (2012) 0.91
The Nucleo-cytoplasmic actin-binding protein CapG lacks a nuclear export sequence present in structurally related proteins. J Biol Chem (2003) 0.90
A llama-derived gelsolin single-domain antibody blocks gelsolin-G-actin interaction. Cell Mol Life Sci (2010) 0.90
Invasion of retinal pigment epithelial cells: N-cadherin, hepatocyte growth factor, and focal adhesion kinase. Invest Ophthalmol Vis Sci (2003) 0.89
Stratifying fascin and cortactin function in invadopodium formation using inhibitory nanobodies and targeted subcellular delocalization. FASEB J (2014) 0.89
Structure and function of the N-cadherin/catenin complex in retinoblastoma. Invest Ophthalmol Vis Sci (2002) 0.89
A new role for nuclear transport factor 2 and Ran: nuclear import of CapG. Traffic (2008) 0.89
G-protein alpha(olf) subunit promotes cellular invasion, survival, and neuroendocrine differentiation in digestive and urogenital epithelial cells. Oncogene (2002) 0.88
An alpaca single-domain antibody blocks filopodia formation by obstructing L-plastin-mediated F-actin bundling. FASEB J (2009) 0.88
Cell biology: actin filaments up against a wall. Nature (2010) 0.88
Multiple isoforms of the tumor suppressor myopodin are simultaneously transcribed in cancer cells. Biochem Biophys Res Commun (2008) 0.88
Alpha-catenin is required for IGF-I-induced cellular migration but not invasion in human colonic cancer cells. Oncogene (2004) 0.87
The actin-capping protein CapG localizes to microtubule-dependent organelles during the cell cycle. Biochem Biophys Res Commun (2009) 0.87
Anaphylactic reactions to bites of the pigeon tick Argas reflexus. Eur J Dermatol (2010) 0.87
Membrane tension and cytoskeleton organization in cell motility. J Phys Condens Matter (2015) 0.86
Mechanistic comparison of the cobalt-substituted and wild-type copper amine oxidase from Hansenula polymorpha. Biochemistry (2002) 0.85
Inhibition of proprotein convertases enhances cell migration and metastases development of human colon carcinoma cells in a rat model. Am J Pathol (2004) 0.84
L-plastin nanobodies perturb matrix degradation, podosome formation, stability and lifetime in THP-1 macrophages. PLoS One (2013) 0.83
Multiple actin binding domains of Ena/VASP proteins determine actin network stiffening. Eur Biophys J (2012) 0.83
Exo70-mediated recruitment of nucleoporin Nup62 at the leading edge of migrating cells is required for cell migration. Traffic (2009) 0.83
Commutators of PAR-1 signaling in cancer cell invasion reveal an essential role of the Rho-Rho kinase axis and tumor microenvironment. Oncogene (2005) 0.82
The tandem PDZ protein Syntenin interacts with the aminoacyl tRNA synthetase complex in a lysyl-tRNA synthetase-dependent manner. J Proteome Res (2008) 0.82
The actin filament cross-linker L-plastin confers resistance to TNF-alpha in MCF-7 breast cancer cells in a phosphorylation-dependent manner. J Cell Mol Med (2009) 0.82
A kelch beta propeller featuring as a G beta structural mimic: reinventing the wheel? Sci STKE (2003) 0.82
Mapping cytoskeletal protein function in cells by means of nanobodies. Cytoskeleton (Hoboken) (2013) 0.82