Published in Blood on October 21, 2008
An emerging role for epigenetic dysregulation in arsenic toxicity and carcinogenesis. Environ Health Perspect (2010) 2.16
Leukaemogenesis: more than mutant genes. Nat Rev Cancer (2010) 2.16
Cooperative and individualistic functions of the microRNAs in the miR-23a~27a~24-2 cluster and its implication in human diseases. Mol Cancer (2010) 2.14
Environmental chemical exposures and human epigenetics. Int J Epidemiol (2011) 1.97
PhenomiR: a knowledgebase for microRNA expression in diseases and biological processes. Genome Biol (2010) 1.79
Identification of keratinocyte growth factor as a target of microRNA-155 in lung fibroblasts: implication in epithelial-mesenchymal interactions. PLoS One (2009) 1.70
A novel network integrating a miRNA-203/SNAI1 feedback loop which regulates epithelial to mesenchymal transition. PLoS One (2012) 1.41
Potentiality of a triple microRNA classifier: miR-193a-3p, miR-23a and miR-338-5p for early detection of colorectal cancer. BMC Cancer (2013) 1.28
miR-661 expression in SNAI1-induced epithelial to mesenchymal transition contributes to breast cancer cell invasion by targeting Nectin-1 and StarD10 messengers. Oncogene (2010) 1.20
Arsenic exposure and the induction of human cancers. J Toxicol (2011) 1.16
Regulation of microRNA expression and function by nuclear receptor signaling. Cell Biosci (2011) 1.12
A miRNA expression signature that separates between normal and malignant prostate tissues. Cancer Cell Int (2011) 1.10
Upregulation of microRNA-125b contributes to leukemogenesis and increases drug resistance in pediatric acute promyelocytic leukemia. Mol Cancer (2011) 1.08
MiR-27a functions as a tumor suppressor in acute leukemia by regulating 14-3-3θ. PLoS One (2012) 1.04
TEL-AML1 regulation of survivin and apoptosis via miRNA-494 and miRNA-320a. Blood (2010) 1.01
Mutant p53-R273H gains new function in sustained activation of EGFR signaling via suppressing miR-27a expression. Cell Death Dis (2013) 1.01
MicroRNAs 221 and 222 regulate the undifferentiated state in mammalian male germ cells. Development (2012) 0.97
PML/RARα-Regulated miR-181a/b Cluster Targets the Tumor Suppressor RASSF1A in Acute Promyelocytic Leukemia. Cancer Res (2015) 0.90
Concerted stimuli regulating osteo-chondral differentiation from stem cells: phenotype acquisition regulated by microRNAs. Acta Pharmacol Sin (2009) 0.88
p16INK4a and its regulator miR-24 link senescence and chondrocyte terminal differentiation-associated matrix remodeling in osteoarthritis. Arthritis Res Ther (2014) 0.88
Differentiation therapy of acute myeloid leukemia. Cancers (Basel) (2011) 0.87
MicroRNA control of myelopoiesis and the differentiation block in acute myeloid leukaemia. J Cell Mol Med (2012) 0.86
The potential of microRNAs in personalized medicine against cancers. Biomed Res Int (2014) 0.84
Upregulation of microRNA-23a regulates proliferation and apoptosis by targeting APAF-1 in laryngeal carcinoma. Oncol Lett (2015) 0.84
Human Leukemic Cells performing Oxidative Phosphorylation (OXPHOS) Generate an Antioxidant Response Independently of Reactive Oxygen species (ROS) Production. EBioMedicine (2015) 0.82
Epigenetics in acute promyelocytic leukaemia pathogenesis and treatment response: a TRAnsition to targeted therapies. Br J Cancer (2014) 0.82
Noncoding RNAs in Acute Myeloid Leukemia: From Key Regulators to Clinical Players. Scientifica (Cairo) (2012) 0.80
miR-146a expression level as a novel putative prognostic marker for acute promyelocytic leukemia. Dis Markers (2014) 0.80
Single-nucleotide polymorphisms among microRNA: big effects on cancer. Chin J Cancer (2011) 0.79
The NF-κB p65/miR-23a-27a-24 cluster is a target for leukemia treatment. Oncotarget (2015) 0.78
miRNA-mediated deregulation in leukemia. Front Genet (2012) 0.78
The lncRNA HOTAIRM1 regulates the degradation of PML-RARA oncoprotein and myeloid cell differentiation by enhancing the autophagy pathway. Cell Death Differ (2016) 0.78
Mining for Candidate Genes Related to Pancreatic Cancer Using Protein-Protein Interactions and a Shortest Path Approach. Biomed Res Int (2015) 0.77
MicroRNAs in Myeloid Hematological Malignancies. Curr Genomics (2015) 0.76
Methylation Status of SP1 Sites within miR-23a-27a-24-2 Promoter Region Influences Laryngeal Cancer Cell Proliferation and Apoptosis. Biomed Res Int (2016) 0.76
Low DICER1 expression is associated with attenuated neutrophil differentiation and autophagy of NB4 APL cells. J Leukoc Biol (2015) 0.75
MicroRNA-27a functions as a tumor suppressor in renal cell carcinoma by targeting epidermal growth factor receptor. Oncol Lett (2016) 0.75
The modulation of MiR-155 and MiR-23a manipulates Klebsiella pneumoniae Adhesion on Human pulmonary Epithelial cells via Integrin α5β1 Signaling. Sci Rep (2016) 0.75
Effect of ATRA and ATO on the expression of tissue factor in NB4 acute promyelocytic leukemia cells and regulatory function of the inflammatory cytokines TNF and IL-1β. Ann Hematol (2017) 0.75
JASPAR: an open-access database for eukaryotic transcription factor binding profiles. Nucleic Acids Res (2004) 19.32
The clonal and mutational evolution spectrum of primary triple-negative breast cancers. Nature (2012) 11.91
JASPAR 2010: the greatly expanded open-access database of transcription factor binding profiles. Nucleic Acids Res (2009) 9.42
A cellular microRNA mediates antiviral defense in human cells. Science (2005) 8.48
TFBS: Computational framework for transcription factor binding site analysis. Bioinformatics (2002) 8.45
A promoter-level mammalian expression atlas. Nature (2014) 6.25
JASPAR 2014: an extensively expanded and updated open-access database of transcription factor binding profiles. Nucleic Acids Res (2013) 6.12
Suppression of microRNA-silencing pathway by HIV-1 during virus replication. Science (2007) 5.07
ConSite: web-based prediction of regulatory elements using cross-species comparison. Nucleic Acids Res (2004) 4.99
oPOSSUM: identification of over-represented transcription factor binding sites in co-expressed genes. Nucleic Acids Res (2005) 4.52
A new generation of JASPAR, the open-access repository for transcription factor binding site profiles. Nucleic Acids Res (2006) 4.32
GAPDH and autophagy preserve survival after apoptotic cytochrome c release in the absence of caspase activation. Cell (2007) 4.22
VPS35 mutations in Parkinson disease. Am J Hum Genet (2011) 4.16
ORegAnno: an open-access community-driven resource for regulatory annotation. Nucleic Acids Res (2007) 3.80
Retracted Probing the microRNA and small interfering RNA pathways with virus-encoded suppressors of RNA silencing. Plant Cell (2004) 3.71
A synonymous variant in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease. Nat Genet (2011) 3.59
Constrained binding site diversity within families of transcription factors enhances pattern discovery bioinformatics. J Mol Biol (2004) 3.54
Arrays of ultraconserved non-coding regions span the loci of key developmental genes in vertebrate genomes. BMC Genomics (2004) 3.08
DNA topoisomerase II in therapy-related acute promyelocytic leukemia. N Engl J Med (2005) 3.06
Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis. Nucleic Acids Res (2010) 2.80
Cancer stem cell definitions and terminology: the devil is in the details. Nat Rev Cancer (2012) 2.76
Conserved vertebrate mir-451 provides a platform for Dicer-independent, Ago2-mediated microRNA biogenesis. Proc Natl Acad Sci U S A (2010) 2.67
Analysis of risk factors for myelodysplasias, leukemias and death from infection among patients with congenital neutropenia. Experience of the French Severe Chronic Neutropenia Study Group. Haematologica (2005) 2.66
RNA interference in mammalian cells by chemically-modified RNA. Biochemistry (2003) 2.62
PAZAR: a framework for collection and dissemination of cis-regulatory sequence annotation. Genome Biol (2007) 2.59
Pegylated interferon-alfa-2a induces complete hematologic and molecular responses with low toxicity in polycythemia vera. Blood (2008) 2.55
Identification of a novel BBS gene (BBS12) highlights the major role of a vertebrate-specific branch of chaperonin-related proteins in Bardet-Biedl syndrome. Am J Hum Genet (2006) 2.44
Matrix metalloproteinases are differentially expressed in adipose tissue during obesity and modulate adipocyte differentiation. J Biol Chem (2003) 2.38
Allele-specific silencing of mutant huntingtin and ataxin-3 genes by targeting expanded CAG repeats in mRNAs. Nat Biotechnol (2009) 2.36
oPOSSUM: integrated tools for analysis of regulatory motif over-representation. Nucleic Acids Res (2007) 2.32
The impact of JAK2 and MPL mutations on diagnosis and prognosis of splanchnic vein thrombosis: a report on 241 cases. Blood (2008) 2.21
Control of vertebrate multiciliogenesis by miR-449 through direct repression of the Delta/Notch pathway. Nat Cell Biol (2011) 2.09
A purified population of multipotent cardiovascular progenitors derived from primate pluripotent stem cells engrafts in postmyocardial infarcted nonhuman primates. J Clin Invest (2010) 2.06
TFCat: the curated catalog of mouse and human transcription factors. Genome Biol (2009) 2.06
Integrated analysis of yeast regulatory sequences for biologically linked clusters of genes. Funct Integr Genomics (2003) 1.98
Alveolar epithelial type I cells contain transport proteins and transport sodium, supporting an active role for type I cells in regulation of lung liquid homeostasis. Proc Natl Acad Sci U S A (2002) 1.95
Association of the multidrug resistance-1 gene single-nucleotide polymorphisms with the tacrolimus dose requirements in renal transplant recipients. J Am Soc Nephrol (2003) 1.93
Signatures of microRNAs and selected microRNA target genes in human melanoma. Cancer Res (2010) 1.90
An open-access long oligonucleotide microarray resource for analysis of the human and mouse transcriptomes. Nucleic Acids Res (2006) 1.87
A regulatory toolbox of MiniPromoters to drive selective expression in the brain. Proc Natl Acad Sci U S A (2010) 1.85
Impact of cytochrome p450 3A5 genetic polymorphism on tacrolimus doses and concentration-to-dose ratio in renal transplant recipients. Transplantation (2003) 1.83
In silico detection of sequence variations modifying transcriptional regulation. PLoS Comput Biol (2007) 1.82
Increased steroidogenic factor-1 dosage triggers adrenocortical cell proliferation and cancer. Mol Endocrinol (2007) 1.81
Comparison of human skeletal myoblasts and bone marrow-derived CD133+ progenitors for the repair of infarcted myocardium. J Am Coll Cardiol (2004) 1.79
Mutations in the ELA2 gene correlate with more severe expression of neutropenia: a study of 81 patients from the French Neutropenia Register. Blood (2004) 1.70
Decoding human regulatory circuits. Genome Res (2004) 1.70
Understanding the language of gene regulation. Genome Biol (2003) 1.70
Identification of keratinocyte growth factor as a target of microRNA-155 in lung fibroblasts: implication in epithelial-mesenchymal interactions. PLoS One (2009) 1.70
The PAZAR database of gene regulatory information coupled to the ORCA toolkit for the study of regulatory sequences. Nucleic Acids Res (2008) 1.66
Prediction of nuclear hormone receptor response elements. Mol Endocrinol (2004) 1.65
Characteristics and outcome of myelodysplastic syndromes (MDS) with isolated 20q deletion: a report on 62 cases. Leuk Res (2011) 1.61
oPOSSUM-3: advanced analysis of regulatory motif over-representation across genes or ChIP-Seq datasets. G3 (Bethesda) (2012) 1.61
TFBSshape: a motif database for DNA shape features of transcription factor binding sites. Nucleic Acids Res (2013) 1.60
PML-RARA-targeted DNA vaccine induces protective immunity in a mouse model of leukemia. Nat Med (2003) 1.60
Transcriptional regulation of beta-secretase by p25/cdk5 leads to enhanced amyloidogenic processing. Neuron (2008) 1.59
Combined treatment with arsenic trioxide and all-trans-retinoic acid in patients with relapsed acute promyelocytic leukemia. J Clin Oncol (2003) 1.57
The next generation of transcription factor binding site prediction. PLoS Comput Biol (2013) 1.55
High molecular response rate of polycythemia vera patients treated with pegylated interferon alpha-2a. Blood (2006) 1.55
Involvement of the secretory pathway and the cytoskeleton in intracellular targeting and tubule assembly of Grapevine fanleaf virus movement protein in tobacco BY-2 cells. Plant Cell (2003) 1.55
DNAJC13 mutations in Parkinson disease. Hum Mol Genet (2013) 1.54
Small RNA sequencing reveals miR-642a-3p as a novel adipocyte-specific microRNA and miR-30 as a key regulator of human adipogenesis. Genome Biol (2011) 1.53
miR-199a-5p Is upregulated during fibrogenic response to tissue injury and mediates TGFbeta-induced lung fibroblast activation by targeting caveolin-1. PLoS Genet (2013) 1.53
Regulog analysis: detection of conserved regulatory networks across bacteria: application to Staphylococcus aureus. Genome Res (2004) 1.52
M-cadherin activates Rac1 GTPase through the Rho-GEF trio during myoblast fusion. Mol Biol Cell (2007) 1.51
Analysis of the ten-eleven translocation 2 (TET2) gene in familial myeloproliferative neoplasms. Blood (2009) 1.47
Is cytarabine useful in the treatment of acute promyelocytic leukemia? Results of a randomized trial from the European Acute Promyelocytic Leukemia Group. J Clin Oncol (2006) 1.46
MSCAN: identification of functional clusters of transcription factor binding sites. Nucleic Acids Res (2004) 1.44
A novel network integrating a miRNA-203/SNAI1 feedback loop which regulates epithelial to mesenchymal transition. PLoS One (2012) 1.41
Real-time genotyping with oligonucleotide probes containing locked nucleic acids. Anal Biochem (2004) 1.40
Design considerations and effects of LNA in PCR primers. Mol Cell Probes (2003) 1.39
Interplay of microRNAs, transcription factors and target genes: linking dynamic expression changes to function. Nucleic Acids Res (2013) 1.38
The V617F JAK 2 mutation is not a frequent event in patients with cerebral venous thrombosis without overt chronic myeloproliferative disorder. Thromb Haemost (2008) 1.38
Reactive oxygen species, DNA damage, and error-prone repair: a model for genomic instability with progression in myeloid leukemia? Cancer Res (2007) 1.36
MicroRNAs and lung cancer: new oncogenes and tumor suppressors, new prognostic factors and potential therapeutic targets. Curr Med Chem (2009) 1.34
Pharmacokinetic interaction between corticosteroids and tacrolimus after renal transplantation. Nephrol Dial Transplant (2003) 1.34
MIR@NT@N: a framework integrating transcription factors, microRNAs and their targets to identify sub-network motifs in a meta-regulation network model. BMC Bioinformatics (2011) 1.33
Dynamics of the yeast transcriptome during wine fermentation reveals a novel fermentation stress response. FEMS Yeast Res (2008) 1.32