Knockdown of Sox4 expression by RNAi induces apoptosis in ACC3 cells.

PubWeight™: 1.44‹?› | Rank: Top 5%

🔗 View Article (PMID 16636670)

Published in Oncogene on April 24, 2006

Authors

P Pramoonjago1, A S Baras, C A Moskaluk

Author Affiliations

1: Department of Pathology and Biochemistry, University of Virginia, Charlottesville, VA 22908, USA.

Articles citing this

Sox17 and Sox4 differentially regulate beta-catenin/T-cell factor activity and proliferation of colon carcinoma cells. Mol Cell Biol (2007) 2.67

Epigenetic repression of microRNA-129-2 leads to overexpression of SOX4 oncogene in endometrial cancer. Cancer Res (2009) 2.23

Genome-wide promoter analysis of the SOX4 transcriptional network in prostate cancer cells. Cancer Res (2009) 1.97

The three SoxC proteins--Sox4, Sox11 and Sox12--exhibit overlapping expression patterns and molecular properties. Nucleic Acids Res (2008) 1.70

Organogenesis relies on SoxC transcription factors for the survival of neural and mesenchymal progenitors. Nat Commun (2010) 1.69

Induction of SOX4 by DNA damage is critical for p53 stabilization and function. Proc Natl Acad Sci U S A (2009) 1.50

Massively parallel signature sequencing and bioinformatics analysis identifies up-regulation of TGFBI and SOX4 in human glioblastoma. PLoS One (2010) 1.39

Critical roles for SoxC transcription factors in development and cancer. Int J Biochem Cell Biol (2009) 1.37

Tiling resolution array CGH and high density expression profiling of urothelial carcinomas delineate genomic amplicons and candidate target genes specific for advanced tumors. BMC Med Genomics (2008) 1.24

The probiotic Lactobacillus GG may augment intestinal host defense by regulating apoptosis and promoting cytoprotective responses in the developing murine gut. Pediatr Res (2008) 1.22

The closely related transcription factors Sox4 and Sox11 function as survival factors during spinal cord development. J Neurochem (2010) 1.08

Prognostic significance of Sox4 expression in human cutaneous melanoma and its role in cell migration and invasion. Am J Pathol (2010) 1.08

Molecular biology of adenoid cystic carcinoma. Head Neck (2011) 1.07

Sox4-mediated Dicer expression is critical for suppression of melanoma cell invasion. Oncogene (2012) 1.06

SOX4 mediates TGF-β-induced expression of mesenchymal markers during mammary cell epithelial to mesenchymal transition. PLoS One (2013) 1.00

The Sex-determining region Y-box 4 and homeobox C6 transcriptional networks in prostate cancer progression: crosstalk with the Wnt, Notch, and PI3K pathways. Am J Pathol (2009) 0.97

Clinical and Prognostic Implications of Transcription Factor SOX4 in Patients with Colon Cancer. PLoS One (2013) 0.93

Developmental biology of gut-probiotic interaction. Gut Microbes (2010) 0.91

Sox4 is required for the survival of pro-B cells. J Immunol (2013) 0.89

Clinical and prognostic association of transcription factor SOX4 in gastric cancer. PLoS One (2012) 0.88

Steroid hormone control of cell death and cell survival: molecular insights using RNAi. PLoS Genet (2009) 0.83

SOX4 expression is closely associated with differentiation and lymph node metastasis in oral squamous cell carcinoma. Med Mol Morphol (2013) 0.83

Adenoid cystic carcinoma: current therapy and potential therapeutic advances based on genomic profiling. Oncotarget (2015) 0.83

SOX4 inhibits GBM cell growth and induces G0/G1 cell cycle arrest through Akt-p53 axis. BMC Neurol (2014) 0.81

The role of Sox genes in lung morphogenesis and cancer. Int J Mol Sci (2012) 0.81

SOX4 expression is associated with treatment failure and chemoradioresistance in oral squamous cell carcinoma. BMC Cancer (2015) 0.81

MicroRNA-132 inhibits cell growth and metastasis in osteosarcoma cell lines possibly by targeting Sox4. Int J Oncol (2015) 0.80

Sox4 Expression Confers Bladder Cancer Stem Cell Properties and Predicts for Poor Patient Outcome. Int J Biol Sci (2015) 0.80

Effects of small interfering RNA targeting thymidylate synthase on survival of ACC3 cells from salivary adenoid cystic carcinoma. BMC Cancer (2008) 0.80

Detailed Analysis of Focal Chromosome Arm 1q and 6p Amplifications in Urothelial Carcinoma Reveals Complex Genomic Events on 1q, and SOX4 as a Possible Auxiliary Target on 6p. PLoS One (2013) 0.79

Hepatitis B virus replication and sex-determining region Y box 4 production are tightly controlled by a novel positive feedback mechanism. Sci Rep (2015) 0.78

High expression of SOX2 is associated with poor prognosis in patients with salivary gland adenoid cystic carcinoma. Int J Mol Sci (2014) 0.77

Immunohistochemical expression of the oncogenic molecules active Stat3 and survivin in benign and malignant salivary gland tumors. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2009) 0.75

The lncRNA CASC15 regulates SOX4 expression in RUNX1-rearranged acute leukemia. Mol Cancer (2017) 0.75

Articles by these authors

DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1. Science (1996) 11.13

Molecular classification of human carcinomas by use of gene expression signatures. Cancer Res (2001) 6.78

Analysis of gene expression identifies candidate markers and pharmacological targets in prostate cancer. Cancer Res (2001) 6.73

Germline BRCA2 gene mutations in patients with apparently sporadic pancreatic carcinomas. Cancer Res (1996) 3.60

Abrogation of the Rb/p16 tumor-suppressive pathway in virtually all pancreatic carcinomas. Cancer Res (1997) 3.17

PAC-1: a mitogen-induced nuclear protein tyrosine phosphatase. Science (1993) 2.80

IL-18, a novel immunoregulatory cytokine, is up-regulated in Crohn's disease: expression and localization in intestinal mucosal cells. J Immunol (1999) 2.58

Activating c-kit gene mutations in human germ cell tumors. Am J Pathol (1999) 2.15

Th1-type responses mediate spontaneous ileitis in a novel murine model of Crohn's disease. J Clin Invest (2001) 1.96

Homozygous deletion map at 18q21.1 in pancreatic cancer. Cancer Res (1996) 1.75

Genetic differences between adenocarcinomas arising in Barrett's esophagus and gastric mucosa. Gastroenterology (2001) 1.74

Antibody blockade of ICAM-1 and VCAM-1 ameliorates inflammation in the SAMP-1/Yit adoptive transfer model of Crohn's disease in mice. Gastroenterology (2001) 1.69

KIT protein expression and analysis of c-kit gene mutation in adenoid cystic carcinoma. Mod Pathol (1999) 1.40

Incidence of loss of heterozygosity at p53 and BRCA1 loci in serous surface carcinoma. Hum Pathol (1999) 1.37

Genetic alterations and epithelial dysplasia in juvenile polyposis syndrome and sporadic juvenile polyps. Am J Pathol (1997) 1.15

TrkC signaling is activated in adenoid cystic carcinoma and requires NT-3 to stimulate invasive behavior. Oncogene (2012) 1.14

Origin of microsatellite instability in gastric cancer. Am J Pathol (1999) 1.10

The multiple endocrine neoplasia type I gene locus is involved in the pathogenesis of type II gastric carcinoids. Gastroenterology (1997) 1.10

Establishing a tumour bank: banking, informatics and ethics. Br J Cancer (2004) 1.09

Allelotype of gastric adenocarcinoma. Cancer Res (1999) 1.08

Inactivation of the E-cadherin gene in sporadic diffuse-type gastric cancer. Mod Pathol (2001) 0.96

Mapping of genetic deletions on the long arm of chromosome 4 in human esophageal adenocarcinomas. Am J Pathol (1999) 0.96

Novel DNA copy number losses in chromosome 12q12--q13 in adenoid cystic carcinoma. Neoplasia (2001) 0.90

Analysis of chromosome 9p21 deletion and p16 gene mutation in salivary gland carcinomas. Hum Pathol (1999) 0.89

Combined genomic and gene expression microarray profiling identifies ECOP as an upregulated gene in squamous cell carcinomas independent of DNA amplification. Oncogene (2009) 0.88

Construct validity in a high-fidelity prostate exam simulator. Prostate Cancer Prostatic Dis (2011) 0.85

Evidence for functional ATP-sensitive (K(ATP)) potassium channels in human and equine articular chondrocytes. Osteoarthritis Cartilage (2006) 0.84

Overexpression of CEBPbeta correlates with decreased TFF1 in gastric cancer. Oncogene (2006) 0.83

An integrated high-resolution physical map of the DPC/BRCA2 region at chromosome 13q12. Cancer Res (1995) 0.82

Surgical management of pulmonary infections in chronic granulomatous disease of childhood. Ann Thorac Surg (1993) 0.82

The effects of frozen tissue storage conditions on the integrity of RNA and protein. Biotech Histochem (2014) 0.80

Thoracotomy for pulmonary mycoses in non-HIV-immunosuppressed patients. Ann Thorac Surg (1994) 0.78

Isolation of YAC insert sequences by representational difference analysis. Nucleic Acids Res (1995) 0.75

Sailing past the horizon. The histologic diagnosis of celiac disease in "nonflat" intestinal mucosa. Am J Clin Pathol (2001) 0.75