Published in Hum Mol Genet on April 27, 2006
A meta-analysis of human embryonic stem cells transcriptome integrated into a web-based expression atlas. Stem Cells (2007) 3.62
Self-renewal of human embryonic stem cells requires insulin-like growth factor-1 receptor and ERBB2 receptor signaling. Blood (2007) 3.05
Revealing a core signaling regulatory mechanism for pluripotent stem cell survival and self-renewal by small molecules. Proc Natl Acad Sci U S A (2010) 3.01
The transcriptional and signalling networks of pluripotency. Nat Cell Biol (2011) 2.54
Phosphoproteomic analysis of human embryonic stem cells. Cell Stem Cell (2009) 2.19
FGF2 sustains NANOG and switches the outcome of BMP4-induced human embryonic stem cell differentiation. Cell Stem Cell (2011) 2.11
Signaling network crosstalk in human pluripotent cells: a Smad2/3-regulated switch that controls the balance between self-renewal and differentiation. Cell Stem Cell (2012) 1.94
A role for NANOG in G1 to S transition in human embryonic stem cells through direct binding of CDK6 and CDC25A. J Cell Biol (2009) 1.67
Culture of human pluripotent stem cells using completely defined conditions on a recombinant E-cadherin substratum. BMC Dev Biol (2010) 1.64
Reciprocal regulation of Akt and Oct4 promotes the self-renewal and survival of embryonal carcinoma cells. Mol Cell (2012) 1.63
Genome-wide identification of microRNA targets in human ES cells reveals a role for miR-302 in modulating BMP response. Genes Dev (2011) 1.55
JNK-induced apoptosis, compensatory growth, and cancer stem cells. Cancer Res (2012) 1.52
A reduction in ATP demand and mitochondrial activity with neural differentiation of human embryonic stem cells. J Cell Sci (2011) 1.50
Integrated chemical genomics reveals modifiers of survival in human embryonic stem cells. Stem Cells (2009) 1.36
Quantifying nuclear p65 as a parameter for NF-κB activation: Correlation between ImageStream cytometry, microscopy, and Western blot. Cytometry A (2011) 1.27
Role of E-cadherin and other cell adhesion molecules in survival and differentiation of human pluripotent stem cells. Cell Adh Migr (2012) 1.27
Mechanics regulates fate decisions of human embryonic stem cells. PLoS One (2012) 1.24
Potential for cripto-1 in defining stem cell-like characteristics in human malignant melanoma. Cell Cycle (2008) 1.20
Epigenetics: judge, jury and executioner of stem cell fate. Epigenetics (2012) 1.17
Reactive oxygen species enhance differentiation of human embryonic stem cells into mesendodermal lineage. Exp Mol Med (2010) 1.14
Genomic chart guiding embryonic stem cell cardiopoiesis. Genome Biol (2008) 1.13
Bcl-xL enhances single-cell survival and expansion of human embryonic stem cells without affecting self-renewal. Stem Cell Res (2011) 1.07
Protective effect of ginseng polysaccharides on influenza viral infection. PLoS One (2012) 1.03
Protein kinase C regulates human pluripotent stem cell self-renewal. PLoS One (2013) 1.03
Innate immunity in human embryonic stem cells: comparison with adult human endothelial cells. PLoS One (2010) 1.02
Stacking the DEK: from chromatin topology to cancer stem cells. Cell Cycle (2012) 1.01
Analysis of an alternative human CD133 promoter reveals the implication of Ras/ERK pathway in tumor stem-like hallmarks. Mol Cancer (2010) 1.01
SNAI1-mediated epithelial-mesenchymal transition confers chemoresistance and cellular plasticity by regulating genes involved in cell death and stem cell maintenance. PLoS One (2013) 1.00
Tyrosine phosphorylation profiling in FGF-2 stimulated human embryonic stem cells. PLoS One (2011) 0.99
Engineering tissue from human embryonic stem cells. J Cell Mol Med (2008) 0.98
Signaling networks in human pluripotent stem cells. Curr Opin Cell Biol (2012) 0.97
Human endogenous retrovirus K (HML-2) RNA and protein expression is a marker for human embryonic and induced pluripotent stem cells. Retrovirology (2013) 0.96
Apert p.Ser252Trp mutation in FGFR2 alters osteogenic potential and gene expression of cranial periosteal cells. Mol Med (2007) 0.95
A large-scale proteomic analysis of human embryonic stem cells. BMC Genomics (2007) 0.95
TBX3 promotes human embryonic stem cell proliferation and neuroepithelial differentiation in a differentiation stage-dependent manner. Stem Cells (2012) 0.92
New opportunities: harnessing induced pluripotency for discovery in diabetes and metabolism. Cell Metab (2013) 0.90
Roles of the cyclooxygenase 2 matrix metalloproteinase 1 pathway in brain metastasis of breast cancer. J Biol Chem (2015) 0.90
Isolation of a native osteoblast matrix with a specific affinity for BMP2. J Mol Histol (2007) 0.90
Versatile inhibitory effects of the flavonoid-derived PI3K/Akt inhibitor, LY294002, on ATP-binding cassette transporters that characterize stem cells. Clin Transl Med (2012) 0.89
Imaging flow cytometry: coping with heterogeneity in biological systems. J Histochem Cytochem (2012) 0.88
Deficiency of Akt1, but not Akt2, attenuates the development of pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol (2014) 0.87
Distinct roles for isoforms of the catalytic subunit of class-IA PI3K in the regulation of behaviour of murine embryonic stem cells. J Cell Sci (2009) 0.86
Where PI3K/Akt meets Smads: the crosstalk determines human embryonic stem cell fate. Cell Stem Cell (2012) 0.86
Phosphatase and tensin homolog regulates the pluripotent state and lineage fate choice in human embryonic stem cells. Stem Cells (2011) 0.85
Induced pluripotent stem cells: emerging techniques for nuclear reprogramming. Antioxid Redox Signal (2011) 0.85
Potential for pharmacological manipulation of human embryonic stem cells. Br J Pharmacol (2013) 0.85
The evolving biology of small molecules: controlling cell fate and identity. Philos Trans R Soc Lond B Biol Sci (2011) 0.85
Common stemness regulators of embryonic and cancer stem cells. World J Stem Cells (2015) 0.84
Protein kinase C-induced early growth response protein-1 binding to SNAIL promoter in epithelial-mesenchymal transition of human embryonic stem cells. Stem Cells Dev (2014) 0.84
A role for SHIP in stem cell biology and transplantation. Curr Stem Cell Res Ther (2008) 0.83
Wilms' tumor blastemal stem cells dedifferentiate to propagate the tumor bulk. Stem Cell Reports (2014) 0.83
Comprehensive quantitative comparison of the membrane proteome, phosphoproteome, and sialiome of human embryonic and neural stem cells. Mol Cell Proteomics (2013) 0.83
A statistical approach for identifying differential distributions in single-cell RNA-seq experiments. Genome Biol (2016) 0.83
Genetic and Epigenetic Regulation of Human Cardiac Reprogramming and Differentiation in Regenerative Medicine. Annu Rev Genet (2015) 0.82
The NF-κB Pathway and Cancer Stem Cells. Cells (2016) 0.82
The Importance of Ubiquitination and Deubiquitination in Cellular Reprogramming. Stem Cells Int (2016) 0.82
Generation and characterization of leukemia inhibitory factor-dependent equine induced pluripotent stem cells from adult dermal fibroblasts. Stem Cells Dev (2014) 0.82
Inhibition of IKK/NF-κB Signaling Enhances Differentiation of Mesenchymal Stromal Cells from Human Embryonic Stem Cells. Stem Cell Reports (2016) 0.82
Nanotopographical Surfaces for Stem Cell Fate Control: Engineering Mechanobiology from the Bottom. Nano Today (2014) 0.81
The role of NF-κB signaling in the maintenance of pluripotency of human induced pluripotent stem cells. PLoS One (2013) 0.81
Porcine skin-derived progenitor (SKP) spheres and neurospheres: Distinct "stemness" identified by microarray analysis. Cell Reprogram (2010) 0.81
Human pluripotent stem cells on artificial microenvironments: a high content perspective. Front Pharmacol (2014) 0.81
Development of Antiviral Innate Immunity During In Vitro Differentiation of Mouse Embryonic Stem Cells. Stem Cells Dev (2016) 0.80
Disrupting the CXCL12/CXCR4 axis disturbs the characteristics of glioblastoma stem-like cells of rat RG2 glioblastoma. Cancer Cell Int (2013) 0.79
Inhibition of apoptosis in human induced pluripotent stem cells during expansion in a defined culture using angiopoietin-1 derived peptide QHREDGS. Biomaterials (2014) 0.78
PTEN Promotes Dopaminergic Neuronal Differentiation Through Regulation of ERK-Dependent Inhibition of S6K Signaling in Human Neural Stem Cells. Stem Cells Transl Med (2016) 0.78
CBARA1 plays a role in stemness and proliferation of human embryonic stem cells. PLoS One (2013) 0.78
Granulosa cell-derived induced pluripotent stem cells exhibit pro-trophoblastic differentiation potential. Stem Cell Res Ther (2015) 0.78
Mechanobiology: a new frontier for human pluripotent stem cells. Integr Biol (Camb) (2013) 0.78
Divergent LIN28-mRNA associations result in translational suppression upon the initiation of differentiation. Nucleic Acids Res (2014) 0.78
CXCR2 and its related ligands play a novel role in supporting the pluripotency and proliferation of human pluripotent stem cells. Stem Cells Dev (2014) 0.78
Pretreatment of Adipose Derived Stem Cells with Curcumin Facilitates Myocardial Recovery via Antiapoptosis and Angiogenesis. Stem Cells Int (2015) 0.78
TRAF2 recruitment via T61 in CD30 drives NFκB activation and enhances hESC survival and proliferation. Mol Biol Cell (2015) 0.78
Ciprofloxacin Improves the Stemness of Human Dermal Papilla Cells. Stem Cells Int (2015) 0.77
Qualitative modeling identifies IL-11 as a novel regulator in maintaining self-renewal in human pluripotent stem cells. Front Physiol (2013) 0.77
Porphyromonas gingivalis lipopolysaccharide activates canonical Wnt/β-catenin and p38 MAPK signalling in stem cells from the apical papilla. Inflammation (2013) 0.77
Human papillomavirus 16 infection predicts poor outcome in patients with esophageal squamous cell carcinoma. Onco Targets Ther (2015) 0.76
Activation of PDK-1 maintains mouse embryonic stem cell self-renewal in a PKB-dependent manner. Oncogene (2013) 0.76
Maternal Wnt/β-catenin signaling coactivates transcription through NF-κB binding sites during Xenopus axis formation. PLoS One (2012) 0.76
Substrates and supplements for hESCs: a critical review. J Assist Reprod Genet (2013) 0.76
Cdh2 stabilizes FGFR1 and contributes to primed-state pluripotency in mouse epiblast stem cells. Sci Rep (2015) 0.76
Protein kinases and associated pathways in pluripotent state and lineage differentiation. Curr Stem Cell Res Ther (2014) 0.75
Glutamine contributes to maintenance of mouse embryonic stem cell self-renewal through PKC-dependent downregulation of HDAC1 and DNMT1/3a. Cell Cycle (2015) 0.75
The human embryonic stem cell proteome revealed by multidimensional fractionation followed by tandem mass spectrometry. Proteomics (2014) 0.75
Pluripotency markers are differentially induced by MEK inhibition in thyroid and melanoma BRAFV600E cell lines. Cancer Biol Ther (2016) 0.75
MSX2 mediates entry of human pluripotent stem cells into mesendoderm by simultaneously suppressing SOX2 and activating NODAL signaling. Cell Res (2015) 0.75
AKT/GSK3β signaling pathway is critically involved in human pluripotent stem cell survival. Sci Rep (2016) 0.75
Co-expression networks in generation of induced pluripotent stem cells. Biol Open (2016) 0.75
The Molecular Basis for the Lack of Inflammatory Responses in Mouse Embryonic Stem Cells and Their Differentiated Cells. J Immunol (2017) 0.75
A critical role for p38MAPK signalling pathway during reprogramming of human fibroblasts to iPSCs. Sci Rep (2017) 0.75
αV β5 and CD44 are oxygen-regulated human embryonic stem cell attachment factors. Biomed Res Int (2013) 0.75
Non-Thermal Atmospheric Pressure Plasma Efficiently Promotes the Proliferation of Adipose Tissue-Derived Stem Cells by Activating NO-Response Pathways. Sci Rep (2016) 0.75
Epigenetic regulation of human SOX3 gene expression during early phases of neural differentiation of NT2/D1 cells. PLoS One (2017) 0.75
Oncogenic K-Ras upregulates ITGA6 expression via FOSL1 to induce anoikis resistance and synergizes with αV-Class integrins to promote EMT. Oncogene (2017) 0.75
Characterization of human embryonic stem cell lines by the International Stem Cell Initiative. Nat Biotechnol (2007) 9.36
Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage. Nat Biotechnol (2011) 3.97
Phenotypic characterization of murine primitive hematopoietic progenitor cells isolated on basis of aldehyde dehydrogenase activity. Stem Cells (2004) 2.80
Mitochondrial dysfunction accounts for the stochastic heterogeneity in telomere-dependent senescence. PLoS Biol (2007) 2.78
Efficient hematopoietic differentiation of human embryonic stem cells on stromal cells derived from hematopoietic niches. Cell Stem Cell (2008) 2.74
Efficient generation and mapping of recessive developmental mutations using ENU mutagenesis. Nat Genet (2002) 2.30
Human induced pluripotent stem cell lines show stress defense mechanisms and mitochondrial regulation similar to those of human embryonic stem cells. Stem Cells (2010) 2.17
Downregulation of NANOG induces differentiation of human embryonic stem cells to extraembryonic lineages. Stem Cells (2005) 2.17
Epigenetic marking correlates with developmental potential in cloned bovine preimplantation embryos. Curr Biol (2003) 2.14
Downregulation of multiple stress defense mechanisms during differentiation of human embryonic stem cells. Stem Cells (2007) 2.07
Telomerase does not counteract telomere shortening but protects mitochondrial function under oxidative stress. J Cell Sci (2008) 1.91
Evc is a positive mediator of Ihh-regulated bone growth that localises at the base of chondrocyte cilia. Development (2007) 1.74
Efficient transgenesis in farm animals by lentiviral vectors. EMBO Rep (2003) 1.72
Glucocorticosteroids increase cell entry by hepatitis C virus. Gastroenterology (2010) 1.70
'Cyclic alopecia' in Msx2 mutants: defects in hair cycling and hair shaft differentiation. Development (2003) 1.70
Restriction landmark genome scanning identifies culture-induced DNA methylation instability in the human embryonic stem cell epigenome. Hum Mol Genet (2007) 1.68
A role for NANOG in G1 to S transition in human embryonic stem cells through direct binding of CDK6 and CDC25A. J Cell Biol (2009) 1.67
Stress defense in murine embryonic stem cells is superior to that of various differentiated murine cells. Stem Cells (2004) 1.67
Progressive loss of PAX9 expression correlates with increasing malignancy of dysplastic and cancerous epithelium of the human oesophagus. J Pathol (2002) 1.60
Fetal health surveillance in labour. J Obstet Gynaecol Can (2002) 1.52
A novel model of urinary tract differentiation, tissue regeneration, and disease: reprogramming human prostate and bladder cells into induced pluripotent stem cells. Eur Urol (2013) 1.51
An autogeneic feeder cell system that efficiently supports growth of undifferentiated human embryonic stem cells. Stem Cells (2005) 1.49
Eya1 is required for the morphogenesis of mammalian thymus, parathyroid and thyroid. Development (2002) 1.49
G1 to S phase cell cycle transition in somatic and embryonic stem cells. J Anat (2008) 1.48
Isolation of primordial germ cells from differentiating human embryonic stem cells. Stem Cells (2008) 1.43
Functional consequences of interactions between Pax9 and Msx1 genes in normal and abnormal tooth development. J Biol Chem (2006) 1.41
Human-serum matrix supports undifferentiated growth of human embryonic stem cells. Stem Cells (2005) 1.39
Derivation of human embryonic stem cells from developing and arrested embryos. Stem Cells (2006) 1.37
Differentiation of human embryonic stem cells to regional specific neural precursors in chemically defined medium conditions. PLoS One (2008) 1.36
Concise review: Mesenchymal stem cell treatment of the complications of diabetes mellitus. Stem Cells (2011) 1.35
Differentiation of human embryonic stem cells into corneal epithelial-like cells by in vitro replication of the corneal epithelial stem cell niche. Stem Cells (2007) 1.33
Epigenetic modification is central to genome reprogramming in somatic cell nuclear transfer. Stem Cells (2005) 1.33
Expression profiling of antisense transcripts on DNA arrays. Physiol Genomics (2006) 1.30
Derivation of a human blastocyst after heterologous nuclear transfer to donated oocytes. Reprod Biomed Online (2005) 1.28
Epigenetic marking prepares the human HOXA cluster for activation during differentiation of pluripotent cells. Stem Cells (2008) 1.27
Efficient stage-specific differentiation of human pluripotent stem cells toward retinal photoreceptor cells. Stem Cells (2012) 1.27
Corneal epithelial stem cells: characterization, culture and transplantation. Regen Med (2006) 1.26
13 years of cultured limbal epithelial cell therapy: a review of the outcomes. J Cell Biochem (2011) 1.26
Successful clinical implementation of corneal epithelial stem cell therapy for treatment of unilateral limbal stem cell deficiency. Stem Cells (2010) 1.21
Daphnia magna ecotoxicogenomics provides mechanistic insights into metal toxicity. Environ Sci Technol (2007) 1.21
Genetic interactions between Pax9 and Msx1 regulate lip development and several stages of tooth morphogenesis. Dev Biol (2010) 1.21
Transplanted oligodendrocytes and motoneuron progenitors generated from human embryonic stem cells promote locomotor recovery after spinal cord transection. Stem Cells (2010) 1.21
A key role for telomerase reverse transcriptase unit in modulating human embryonic stem cell proliferation, cell cycle dynamics, and in vitro differentiation. Stem Cells (2008) 1.20
Derivation of human embryonic stem cells from day-8 blastocysts recovered after three-step in vitro culture. Stem Cells (2004) 1.19
Challenges of stem cell therapy for spinal cord injury: human embryonic stem cells, endogenous neural stem cells, or induced pluripotent stem cells? Stem Cells (2010) 1.17
Perspectives and future directions of human pluripotent stem cell-based therapies: lessons from Geron's clinical trial for spinal cord injury. Stem Cells Dev (2013) 1.16
Activated spinal cord ependymal stem cells rescue neurological function. Stem Cells (2009) 1.14
FM19G11, a new hypoxia-inducible factor (HIF) modulator, affects stem cell differentiation status. J Biol Chem (2009) 1.14
Recurrent urinary tract infection. J Obstet Gynaecol Can (2010) 1.13
Tissue engineering of tooth crown, root, and periodontium. Tissue Eng (2006) 1.13
Investigating gradients of gene expression involved in early human cortical development. J Anat (2010) 1.12
Hypoxia promotes efficient differentiation of human embryonic stem cells to functional endothelium. Stem Cells (2010) 1.11
Derivation and functional analysis of patient-specific induced pluripotent stem cells as an in vitro model of chronic granulomatous disease. Stem Cells (2012) 1.11
SCL/TAL1 regulates hematopoietic specification from human embryonic stem cells. Mol Ther (2012) 1.09
An important role for CDK2 in G1 to S checkpoint activation and DNA damage response in human embryonic stem cells. Stem Cells (2011) 1.09
Reduction of Pax9 gene dosage in an allelic series of mouse mutants causes hypodontia and oligodontia. Hum Mol Genet (2005) 1.09
Concise review: putting a finger on stem cell biology: zinc finger nuclease-driven targeted genetic editing in human pluripotent stem cells. Stem Cells (2011) 1.08
Pax9 is required for filiform papilla development and suppresses skin-specific differentiation of the mammalian tongue epithelium. Mech Dev (2004) 1.08
Concise review: Therapeutic potential of mesenchymal stem cells for the treatment of acute liver failure and cirrhosis. Stem Cells (2014) 1.06
Command and control in emergency services operations: a social network analysis. Ergonomics (2006) 1.06
Putative role of hyaluronan and its related genes, HAS2 and RHAMM, in human early preimplantation embryogenesis and embryonic stem cell characterization. Stem Cells (2007) 1.04