Giuseppe Manco

Author PubWeight™ 42.68‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Prion strain discrimination using luminescent conjugated polymers. Nat Methods 2007 2.62
2 De novo generation of a transmissible spongiform encephalopathy by mouse transgenesis. Proc Natl Acad Sci U S A 2008 2.10
3 The latent promiscuity of newly identified microbial lactonases is linked to a recently diverged phosphotriesterase. Biochemistry 2006 2.02
4 PrPSc in mammary glands of sheep affected by scrapie and mastitis. Nat Med 2005 1.66
5 Structural basis for natural lactonase and promiscuous phosphotriesterase activities. J Mol Biol 2008 1.43
6 A molecular switch controls interspecies prion disease transmission in mice. J Clin Invest 2010 1.41
7 Strain fidelity of chronic wasting disease upon murine adaptation. J Virol 2006 1.40
8 A thermostable phosphotriesterase from the archaeon Sulfolobus solfataricus: cloning, overexpression and properties. Extremophiles 2005 1.27
9 Phenylbutyrate therapy for pyruvate dehydrogenase complex deficiency and lactic acidosis. Sci Transl Med 2013 1.02
10 Spongiform encephalopathy in transgenic mice expressing a point mutation in the β2-α2 loop of the prion protein. J Neurosci 2011 0.99
11 Structural determinants of the high thermal stability of SsoPox from the hyperthermophilic archaeon Sulfolobus solfataricus. Extremophiles 2009 0.98
12 A new phosphotriesterase from Sulfolobus acidocaldarius and its comparison with the homologue from Sulfolobus solfataricus. Biochimie 2007 0.96
13 Role of the N terminus in enzyme activity, stability and specificity in thermophilic esterases belonging to the HSL family. J Mol Biol 2005 0.94
14 Use of an inhibitor to identify members of the hormone-sensitive lipase family. Biochemistry 2006 0.90
15 Modular organization of a Cdc6-like protein from the crenarchaeon Sulfolobus solfataricus. Biochem J 2004 0.90
16 A substrate-induced switch in the reaction mechanism of a thermophilic esterase: kinetic evidences and structural basis. J Biol Chem 2003 0.89
17 Bacterial colitis increases susceptibility to oral prion disease. J Infect Dis 2009 0.89
18 Improving the promiscuous nerve agent hydrolase activity of a thermostable archaeal lactonase. Bioresour Technol 2010 0.89
19 Crystallization and preliminary X-ray diffraction analysis of the hyperthermophilic Sulfolobus solfataricus phosphotriesterase. Acta Crystallogr Sect F Struct Biol Cryst Commun 2007 0.88
20 Functional and structural features of the oxyanion hole in a thermophilic esterase from Alicyclobacillus acidocaldarius. Proteins 2008 0.88
21 Denaturing action of urea and guanidine hydrochloride towards two thermophilic esterases. Biochem J 2002 0.87
22 The conserved N-terminal helix of acylpeptide hydrolase from archaeon Aeropyrum pernix K1 is important for its hyperthermophilic activity. Biochim Biophys Acta 2008 0.82
23 The crystal structure of an EST2 mutant unveils structural insights on the H group of the carboxylesterase/lipase family. J Mol Biol 2004 0.81
24 Alicyclobacillus acidocaldarius thermophilic esterase EST2's activity in milk and cheese models. Appl Environ Microbiol 2006 0.81
25 Comprehensive analysis of surface charged residues involved in thermal stability in Alicyclobacillus acidocaldarius esterase 2. Protein Eng Des Sel 2012 0.81
26 Temperature- and denaturant-induced unfolding of two thermophilic esterases. Biochemistry 2002 0.80
27 EBP1 and DRBP76/NF90 binding proteins are included in the major histocompatibility complex class II RNA operon. Nucleic Acids Res 2011 0.80
28 Evolution in the amidohydrolase superfamily: substrate-assisted gain of function in the E183K mutant of a phosphotriesterase-like metal-carboxylesterase. Biochemistry 2009 0.80
29 Crystallization and preliminary X-ray diffraction studies of Aes acetyl-esterase from Escherichia coli. Acta Crystallogr D Biol Crystallogr 2003 0.79
30 The Aes protein and the monomeric alpha-galactosidase from Escherichia coli form a non-covalent complex. Implications for the regulation of carbohydrate metabolism. J Biol Chem 2002 0.78
31 Thermostable esterase 2 from Alicyclobacillus acidocaldarius as biosensor for the detection of organophosphate pesticides. Anal Chem 2011 0.78
32 Role of the N-terminal region for the conformational stability of esterase 2 from Alicyclobacillus acidocaldarius. Biophys Chem 2007 0.77
33 Irreversible inhibition of the thermophilic esterase EST2 from Alicyclobacillus acidocaldarius. Extremophiles 2008 0.77
34 Redox stress proteins are involved in adaptation response of the hyperthermoacidophilic archaeon Sulfolobus solfataricus to nickel challenge. Microb Cell Fact 2007 0.77
35 Hyperthermophilic phosphotriesterases/lactonases for the environment and human health. Environ Technol 2010 0.76
36 Structural and kinetic overview of the carboxylesterase EST2 from alicyclobacillus acidocaldarius: a comparison with the other members of the HSL family. Protein Pept Lett 2009 0.76
37 Mutational analysis of GstI protein, a glutamine synthetase translational inhibitor of Rhizobium leguminosarum. FEBS Lett 2004 0.76
38 Effect of trifluoroethanol on the conformational stability of a hyperthermophilic esterase: a CD study. Biophys Chem 2003 0.76
39 Mn2+ modulates the kinetic properties of an archaeal member of the PLL family. Chem Biol Interact 2012 0.76
40 Enlarging the substrate portfolio of the thermophilic esterase EST2 from Alicyclobacillus acidocaldarius. Extremophiles 2015 0.76
41 Differential inhibition of PDKs by phenylbutyrate and enhancement of pyruvate dehydrogenase complex activity by combination with dichloroacetate. J Inherit Metab Dis 2015 0.76
42 Denaturant-induced unfolding of the acetyl-esterase from Escherichia coli. Biochemistry 2004 0.75
43 SSoNDelta and SSoNDeltalong: two thermostable esterases from the same ORF in the archaeon Sulfolobus solfataricus? Archaea 2007 0.75
44 Non-lipolytic and lipolytic sequence-related carboxylesterases: a comparative study of the structure-function relationships of rabbit liver esterase 1 and bovine pancreatic bile-salt-activated lipase. Biochim Biophys Acta 2010 0.75
45 Five-substrate cocktail as a sensor array for measuring enzyme activity fingerprints of lipases and esterases. Anal Chem 2011 0.75
46 A proteomic approach to study Escherichia coli. Acetyl esterase interactors unveil a sequence motif involved in protein-protein interaction. Protein Pept Lett 2008 0.75
47 Carboxylesterases: a world with still words to say. Protein Pept Lett 2009 0.75
48 A further biochemical characterization of DrPLL the thermophilic lactonase from Deinococcus radiodurans. Protein Pept Lett 2013 0.75