PubRank

Xuesong Liu

Author PubWeight™ 49.77‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 ABT-888, an orally active poly(ADP-ribose) polymerase inhibitor that potentiates DNA-damaging agents in preclinical tumor models. Clin Cancer Res 2007 5.75
2 Potent and selective inhibitors of Akt kinases slow the progress of tumors in vivo. Mol Cancer Ther 2005 2.15
3 Discovery of the Poly(ADP-ribose) polymerase (PARP) inhibitor 2-[(R)-2-methylpyrrolidin-2-yl]-1H-benzimidazole-4-carboxamide (ABT-888) for the treatment of cancer. J Med Chem 2009 1.68
4 ABT-888 confers broad in vivo activity in combination with temozolomide in diverse tumors. Clin Cancer Res 2009 1.36
5 Survivin enhances Aurora-B kinase activity and localizes Aurora-B in human cells. J Biol Chem 2002 1.35
6 PIKE/nuclear PI 3-kinase signaling mediates the antiapoptotic actions of NGF in the nucleus. EMBO J 2004 1.28
7 Disruption of palladin results in neural tube closure defects in mice. Mol Cell Neurosci 2005 1.26
8 Synthesis and SAR of novel tricyclic quinoxalinone inhibitors of poly(ADP-ribose)polymerase-1 (PARP-1). Bioorg Med Chem Lett 2009 1.23
9 The PARP inhibitor, ABT-888 potentiates temozolomide: correlation with drug levels and reduction in PARP activity in vivo. Anticancer Res 2008 1.12
10 Syntheses of potent, selective, and orally bioavailable indazole-pyridine series of protein kinase B/Akt inhibitors with reduced hypotension. J Med Chem 2007 1.06
11 Synthesis and SAR of indazole-pyridine based protein kinase B/Akt inhibitors. Bioorg Med Chem 2006 0.99
12 Establishment of an ELISA system for determining soluble LAIR-1 levels in sera of patients with HFRS and kidney transplant. J Immunol Methods 2004 0.98
13 Ubiquitin-specific cysteine protease 2a (USP2a) regulates the stability of Aurora-A. J Biol Chem 2011 0.97
14 Pseudosubstrate peptides inhibit Akt and induce cell growth inhibition. Biochemistry 2004 0.93
15 Optimization of phenyl-substituted benzimidazole carboxamide poly(ADP-ribose) polymerase inhibitors: identification of (S)-2-(2-fluoro-4-(pyrrolidin-2-yl)phenyl)-1H-benzimidazole-4-carboxamide (A-966492), a highly potent and efficacious inhibitor. J Med Chem 2010 0.92
16 Brainstem gangliogliomas: a retrospective series. J Neurosurg 2013 0.92
17 Optimal classes of chemotherapeutic agents sensitized by specific small-molecule inhibitors of akt in vitro and in vivo. Neoplasia 2005 0.91
18 Near infrared spectroscopy in combination with chemometrics as a process analytical technology (PAT) tool for on-line quantitative monitoring of alcohol precipitation. J Pharm Biomed Anal 2013 0.87
19 Discovery and SAR of oxindole-pyridine-based protein kinase B/Akt inhibitors for treating cancers. Bioorg Med Chem Lett 2006 0.87
20 Current status and future developments in preparation and application of colloidal crystals. Chem Soc Rev 2013 0.87
21 Platelet-activating factor-induced apoptosis is blocked by Bcl-2 in rat intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol 2003 0.85
22 Physical properties and biocompatibility of a porous chitosan-based fiber-reinforced conduit for nerve regeneration. Biotechnol Lett 2007 0.85
23 9.1C3 is identical to LAIR-1, which is expressed on hematopoietic progenitors. Biochem Biophys Res Commun 2003 0.83
24 Discovery and SAR of 2-(1-propylpiperidin-4-yl)-1H-benzimidazole-4-carboxamide: A potent inhibitor of poly(ADP-ribose) polymerase (PARP) for the treatment of cancer. Bioorg Med Chem 2008 0.82
25 [In-line monitoring of blending process of Zhongsheng pill powder using miniature near-infrared analyzer]. Zhongguo Zhong Yao Za Zhi 2011 0.82
26 Synthesis and structure-activity relationship of 3,4'-bispyridinylethylenes: discovery of a potent 3-isoquinolinylpyridine inhibitor of protein kinase B (PKB/Akt) for the treatment of cancer. Bioorg Med Chem Lett 2006 0.82
27 Isoquinoline-pyridine-based protein kinase B/Akt antagonists: SAR and in vivo antitumor activity. Bioorg Med Chem Lett 2006 0.82
28 Pharmacological characterization of recombinant N-type calcium channel (Cav2.2) mediated calcium mobilization using FLIPR. Biochem Pharmacol 2006 0.81
29 Separation and quantitative determination of sesquiterpene lactones in Lindera aggregata (wu-yao) by ultra-performance LC-MS/MS. J Sep Sci 2010 0.81
30 Synthesis and SAR of novel, potent and orally bioavailable benzimidazole inhibitors of poly(ADP-ribose) polymerase (PARP) with a quaternary methylene-amino substituent. Bioorg Med Chem Lett 2008 0.81
31 Synthesis and evaluation of a new generation of orally efficacious benzimidazole-based poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors as anticancer agents. J Med Chem 2009 0.80
32 Design and synthesis of pyridine-pyrazolopyridine-based inhibitors of protein kinase B/Akt. Bioorg Med Chem 2007 0.79
33 Discovery and SAR of substituted 3-oxoisoindoline-4-carboxamides as potent inhibitors of poly(ADP-ribose) polymerase (PARP) for the treatment of cancer. Bioorg Med Chem Lett 2009 0.79
34 PARP inhibitors attenuate chemotherapy-induced painful neuropathy. J Peripher Nerv Syst 2012 0.79
35 Discovery of trans-3,4'-bispyridinylethylenes as potent and novel inhibitors of protein kinase B (PKB/Akt) for the treatment of cancer: Synthesis and biological evaluation. Bioorg Med Chem Lett 2006 0.79
36 GC-MS of volatile components of Schisandra chinensis obtained by supercritical fluid and conventional extraction. J Sep Sci 2008 0.78
37 Protective effects of cationic bovine serum albumin-conjugated PEGylated tanshinone IIA nanoparticles on cerebral ischemia. Biomaterials 2012 0.78
38 A reliable isotope dilution method for simultaneous determination of fumonisins B1, B2 and B3 in traditional Chinese medicines by ultra-high-performance liquid chromatography-tandem mass spectrometry. J Sep Sci 2010 0.78
39 A rapid method with ultra-high-performance liquid chromatography-tandem mass spectrometry for simultaneous determination of five type B trichothecenes in traditional Chinese medicines. J Sep Sci 2010 0.78
40 Preparation and application of monoclonal antibody against hNDRG2. Appl Biochem Biotechnol 2008 0.78
41 Investigation of an on-line detection method combining near infrared spectroscopy with local partial least squares regression for the elution process of sodium aescinate. Spectrochim Acta A Mol Biomol Spectrosc 2013 0.77
42 Penetration effect of ostrich oil as a promising vehicle on transdermal delivery of sinomenine. J Oleo Sci 2013 0.77
43 Targeting PD-1 and Tim-3 Pathways to Reverse CD8 T-Cell Exhaustion and Enhance Ex Vivo T-Cell Responses to Autologous Dendritic/Tumor Vaccines. J Immunother 2016 0.77
44 Retinal whole genome microarray analysis and early morphological changes in the optic nerves of monkeys after an intraorbital nerve irradiated injury. Mol Vis 2011 0.77
45 Identification of a novel 3,5-disubstituted pyridine as a potent, selective, and orally active inhibitor of Akt1 kinase. Bioorg Med Chem Lett 2006 0.77
46 Characterization of the neutralizing activity of three anti-human TNF monoclonal antibodies and prediction of their TNF epitopes by molecular modeling and mutant protein approach. Immunol Lett 2005 0.77
47 [Research on technological process of two-pot countercurrent extraction of hydroxysafflor yellow A]. Zhongguo Zhong Yao Za Zhi 2009 0.77
48 Novel antagonist antibody to TLR3 blocks poly(I:C)-induced inflammation in vivo and in vitro. Cell Immunol 2010 0.77
49 Chemical composition of essential oils and hydrosols from fresh flowers of Cerasus subhirtella and Cerasus serrulata from East China. Nat Prod Res 2014 0.76
50 Discovery and SAR of orally efficacious tetrahydropyridopyridazinone PARP inhibitors for the treatment of cancer. Bioorg Med Chem 2012 0.75
51 [Preparation of monoclonal antibodies against flagellin core protein of Vibrio vulnificus and its application in testing Vibrio vulnificus from food products]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2013 0.75
52 Nano/microstructured ion exchange resins and their applications. J Nanosci Nanotechnol 2014 0.75
53 [Preparation of monoclonal antibodies against flagellin core protein of Vibrio cholerae and its application in establishing double-antibody sandwich ELISA for testing Vibrio cholerae from food products]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2013 0.75
54 [Fast analytical method on content and transfer rate of marker component in ethanol precipitation of cinobufacini by near infrared spectroscopy]. Zhongguo Zhong Yao Za Zhi 2011 0.75
55 [Preparation of monoclonal antibodies against flagellin core protein of Vibrio parahaemolyticus and its activity analysis]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2013 0.75
56 Dual-core antiresonant hollow core fibers. Opt Express 2016 0.75
57 [Microsurgical treatment and facial nerve preservation in 400 cases of giant acoustic neuromas]. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2014 0.75
58 In-line monitoring of extraction process of scutellarein from Erigeron breviscapus (vant.) Hand-Mazz based on qualitative and quantitative uses of near-infrared spectroscopy. Spectrochim Acta A Mol Biomol Spectrosc 2011 0.75
59 [Effect of prone position ventilation on respiratory mechanics and prognosis in patients with acute respiratory distress syndrome concurrent with interstitial lung disease]. Zhonghua Wei Zhong Bing Ji Jiu Yi Xue 2015 0.75
60 Generation and evaluation of mammalian secreted and membrane protein expression libraries for high-throughput target discovery. Protein Expr Purif 2011 0.75
61 Mature teratoma in cerebellopontine angle in a 70-year-old female: a rare tumor with exceptional location, age, and presentation. Neurol India 2013 0.75
62 Orthogonal array design for the optimization of supercritical fluid extraction of tanshinones from Danshen. J Sep Sci 2008 0.75
63 Plasma pharmacokinetics and tissue distribution study of physalin D in rats by ultra-pressure liquid chromatography with tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 2011 0.75
64 [Study on fast quality control in extracting process of Paeonia lactiflora using near infrared spectroscopy]. Zhongguo Zhong Yao Za Zhi 2009 0.75