Published in Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi on January 01, 2014
ABT-888, an orally active poly(ADP-ribose) polymerase inhibitor that potentiates DNA-damaging agents in preclinical tumor models. Clin Cancer Res (2007) 5.75
Potent and selective inhibitors of Akt kinases slow the progress of tumors in vivo. Mol Cancer Ther (2005) 2.15
Discovery of the Poly(ADP-ribose) polymerase (PARP) inhibitor 2-[(R)-2-methylpyrrolidin-2-yl]-1H-benzimidazole-4-carboxamide (ABT-888) for the treatment of cancer. J Med Chem (2009) 1.68
ABT-888 confers broad in vivo activity in combination with temozolomide in diverse tumors. Clin Cancer Res (2009) 1.36
Survivin enhances Aurora-B kinase activity and localizes Aurora-B in human cells. J Biol Chem (2002) 1.35
PIKE/nuclear PI 3-kinase signaling mediates the antiapoptotic actions of NGF in the nucleus. EMBO J (2004) 1.28
Disruption of palladin results in neural tube closure defects in mice. Mol Cell Neurosci (2005) 1.26
Synthesis and SAR of novel tricyclic quinoxalinone inhibitors of poly(ADP-ribose)polymerase-1 (PARP-1). Bioorg Med Chem Lett (2009) 1.23
Enhancing the Curie temperature of ferromagnetic semiconductor (Ga,Mn)As to 200 K via nanostructure engineering. Nano Lett (2011) 1.20
The control of axillary meristem fate in the maize ramosa pathway. Development (2010) 1.14
The PARP inhibitor, ABT-888 potentiates temozolomide: correlation with drug levels and reduction in PARP activity in vivo. Anticancer Res (2008) 1.12
Mechanical force modulates global gene expression and beta-catenin signaling in colon cancer cells. J Cell Sci (2007) 1.11
Syntheses of potent, selective, and orally bioavailable indazole-pyridine series of protein kinase B/Akt inhibitors with reduced hypotension. J Med Chem (2007) 1.06
The CUBLAS and CULA based GPU acceleration of adaptive finite element framework for bioluminescence tomography. Opt Express (2010) 1.04
Clinical characteristics and treatment of gestational trophoblastic tumor with vaginal metastasis. Gynecol Oncol (2002) 1.02
Synthesis and SAR of indazole-pyridine based protein kinase B/Akt inhibitors. Bioorg Med Chem (2006) 0.99
Establishment of an ELISA system for determining soluble LAIR-1 levels in sera of patients with HFRS and kidney transplant. J Immunol Methods (2004) 0.98
Ubiquitin-specific cysteine protease 2a (USP2a) regulates the stability of Aurora-A. J Biol Chem (2011) 0.97
Pseudosubstrate peptides inhibit Akt and induce cell growth inhibition. Biochemistry (2004) 0.93
Brainstem gangliogliomas: a retrospective series. J Neurosurg (2013) 0.92
Purely electronic switching with high uniformity, resistance tunability, and good retention in Pt-dispersed SiO2 thin films for ReRAM. Adv Mater (2011) 0.91
Optimal classes of chemotherapeutic agents sensitized by specific small-molecule inhibitors of akt in vitro and in vivo. Neoplasia (2005) 0.91
Detection of apoptosis based on the interaction between annexin V and phosphatidylserine. Anal Chem (2009) 0.89
Arabidopsis CPR5 independently regulates seed germination and postgermination arrest of development through LOX pathway and ABA signaling. PLoS One (2011) 0.88
Evaluation of the simplified spherical harmonics approximation in bioluminescence tomography through heterogeneous mouse models. Opt Express (2010) 0.87
Near infrared spectroscopy in combination with chemometrics as a process analytical technology (PAT) tool for on-line quantitative monitoring of alcohol precipitation. J Pharm Biomed Anal (2013) 0.87
Discovery and SAR of oxindole-pyridine-based protein kinase B/Akt inhibitors for treating cancers. Bioorg Med Chem Lett (2006) 0.87
A trust region method in adaptive finite element framework for bioluminescence tomography. Opt Express (2010) 0.87
Current status and future developments in preparation and application of colloidal crystals. Chem Soc Rev (2013) 0.87
Fast-specific tomography imaging via Cerenkov emission. Mol Imaging Biol (2012) 0.85
The effect of intermittent hypoxia on bodyweight, serum glucose and cholesterol in obesity mice. Pak J Biol Sci (2008) 0.85
Sertoli-Leydig cell tumor presenting hyperestrogenism in a postmenopausal woman: a case report and review of the literature. Taiwan J Obstet Gynecol (2012) 0.85
Platelet-activating factor-induced apoptosis is blocked by Bcl-2 in rat intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol (2003) 0.85
Physical properties and biocompatibility of a porous chitosan-based fiber-reinforced conduit for nerve regeneration. Biotechnol Lett (2007) 0.85
Trichoderone, a novel cytotoxic cyclopentenone and cholesta-7, 22-diene-3 beta, 5 alpha, 6 beta-triol, with new activities from the marine-derived fungus Trichoderma sp. J Ind Microbiol Biotechnol (2010) 0.85
9.1C3 is identical to LAIR-1, which is expressed on hematopoietic progenitors. Biochem Biophys Res Commun (2003) 0.83
Transcriptional activation by extradenticle in the Drosophila visceral mesoderm. Dev Biol (2006) 0.83
A novel nonsense mutation in PAX9 is associated with sporadic hypodontia. Mutagenesis (2011) 0.82
Isoquinoline-pyridine-based protein kinase B/Akt antagonists: SAR and in vivo antitumor activity. Bioorg Med Chem Lett (2006) 0.82
Discovery and SAR of 2-(1-propylpiperidin-4-yl)-1H-benzimidazole-4-carboxamide: A potent inhibitor of poly(ADP-ribose) polymerase (PARP) for the treatment of cancer. Bioorg Med Chem (2008) 0.82
[In-line monitoring of blending process of Zhongsheng pill powder using miniature near-infrared analyzer]. Zhongguo Zhong Yao Za Zhi (2011) 0.82
Synthesis and structure-activity relationship of 3,4'-bispyridinylethylenes: discovery of a potent 3-isoquinolinylpyridine inhibitor of protein kinase B (PKB/Akt) for the treatment of cancer. Bioorg Med Chem Lett (2006) 0.82
Separation and quantitative determination of sesquiterpene lactones in Lindera aggregata (wu-yao) by ultra-performance LC-MS/MS. J Sep Sci (2010) 0.81
Mimecan is involved in aortic hypertrophy induced by sinoaortic denervation in rats. Mol Cell Biochem (2011) 0.81
Synthesis and SAR of novel, potent and orally bioavailable benzimidazole inhibitors of poly(ADP-ribose) polymerase (PARP) with a quaternary methylene-amino substituent. Bioorg Med Chem Lett (2008) 0.81
Pharmacological characterization of recombinant N-type calcium channel (Cav2.2) mediated calcium mobilization using FLIPR. Biochem Pharmacol (2006) 0.81
Optimization of expression of an annexin V-hirudin chimeric protein in Escherichia coli. Microbiol Res (2004) 0.81
A modified inexpensive transobturator vaginal tape inside-out procedure versus tension-free vaginal tape for the treatment of SUI: a prospective comparative study. Arch Gynecol Obstet (2011) 0.80
Synthesis and evaluation of a new generation of orally efficacious benzimidazole-based poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors as anticancer agents. J Med Chem (2009) 0.80
Malaria sporozoite antigen-directed genome-wide response in transgenic Drosophila. Genesis (2009) 0.80
Overexpression of human SPATA17 protein induces germ cell apoptosis in transgenic male mice. Mol Biol Rep (2012) 0.80
Design and synthesis of pyridine-pyrazolopyridine-based inhibitors of protein kinase B/Akt. Bioorg Med Chem (2007) 0.79
PARP inhibitors attenuate chemotherapy-induced painful neuropathy. J Peripher Nerv Syst (2012) 0.79
Discovery and SAR of substituted 3-oxoisoindoline-4-carboxamides as potent inhibitors of poly(ADP-ribose) polymerase (PARP) for the treatment of cancer. Bioorg Med Chem Lett (2009) 0.79
Evaluation of adenosine preconditioning with 99mTc-His10-annexin V in a porcine model of myocardium ischemia and reperfusion injury: preliminary study. Nucl Med Biol (2010) 0.79
Discovery of trans-3,4'-bispyridinylethylenes as potent and novel inhibitors of protein kinase B (PKB/Akt) for the treatment of cancer: Synthesis and biological evaluation. Bioorg Med Chem Lett (2006) 0.79
Preparation and application of monoclonal antibody against hNDRG2. Appl Biochem Biotechnol (2008) 0.78
Protective effects of cationic bovine serum albumin-conjugated PEGylated tanshinone IIA nanoparticles on cerebral ischemia. Biomaterials (2012) 0.78
An inexpensive modified transobturator vaginal tape inside-out procedure for the surgical treatment of female stress urinary incontinence. Int Urogynecol J Pelvic Floor Dysfunct (2009) 0.78
GC-MS of volatile components of Schisandra chinensis obtained by supercritical fluid and conventional extraction. J Sep Sci (2008) 0.78
A rapid method with ultra-high-performance liquid chromatography-tandem mass spectrometry for simultaneous determination of five type B trichothecenes in traditional Chinese medicines. J Sep Sci (2010) 0.78
Penetration effect of ostrich oil as a promising vehicle on transdermal delivery of sinomenine. J Oleo Sci (2013) 0.77
[Research on technological process of two-pot countercurrent extraction of hydroxysafflor yellow A]. Zhongguo Zhong Yao Za Zhi (2009) 0.77
Characterization of the neutralizing activity of three anti-human TNF monoclonal antibodies and prediction of their TNF epitopes by molecular modeling and mutant protein approach. Immunol Lett (2005) 0.77
Novel antagonist antibody to TLR3 blocks poly(I:C)-induced inflammation in vivo and in vitro. Cell Immunol (2010) 0.77
Retinal whole genome microarray analysis and early morphological changes in the optic nerves of monkeys after an intraorbital nerve irradiated injury. Mol Vis (2011) 0.77
Primary pituitary lymphoma in an immunocompetent patient: a rare clinical entity. J Neurol (2011) 0.77
Investigation of an on-line detection method combining near infrared spectroscopy with local partial least squares regression for the elution process of sodium aescinate. Spectrochim Acta A Mol Biomol Spectrosc (2013) 0.77
Targeting PD-1 and Tim-3 Pathways to Reverse CD8 T-Cell Exhaustion and Enhance Ex Vivo T-Cell Responses to Autologous Dendritic/Tumor Vaccines. J Immunother (2016) 0.77
Identification of a novel 3,5-disubstituted pyridine as a potent, selective, and orally active inhibitor of Akt1 kinase. Bioorg Med Chem Lett (2006) 0.77
Altered microRNA expression profile in maternal and fetal liver of HBV transgenic mouse model. J Matern Fetal Neonatal Med (2012) 0.77
Chemical composition of essential oils and hydrosols from fresh flowers of Cerasus subhirtella and Cerasus serrulata from East China. Nat Prod Res (2014) 0.76
Isolated intracranial Rosai-Dorfman disease presenting as mental deterioration. Clin Neurol Neurosurg (2012) 0.76
Effects of vitamin C, vitamin E, and molecular hydrogen on the placental function in trophoblast cells. Arch Gynecol Obstet (2015) 0.75
Editorial advances on uncertain reasoning in intelligent systems. IEEE Trans Syst Man Cybern B Cybern (2002) 0.75
[The effect of oxidative stress on aorta endothelial cell in chronic intermittent hypoxia animal model]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi (2012) 0.75
[Preparation of monoclonal antibodies against flagellin core protein of Vibrio vulnificus and its application in testing Vibrio vulnificus from food products]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi (2013) 0.75
Radiological features of craniopharyngiomas located in the posterior fossa. J Neurol Sci (2009) 0.75
[Preparation of monoclonal antibodies against flagellin core protein of Vibrio cholerae and its application in establishing double-antibody sandwich ELISA for testing Vibrio cholerae from food products]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi (2013) 0.75
Formation mechanism and a universal period formula for the CCD moiré. Opt Express (2014) 0.75
Nano/microstructured ion exchange resins and their applications. J Nanosci Nanotechnol (2014) 0.75
Tuberculous abdominal aortic aneurysm with alimentary tract hemorrhage: a case report with medico-legal implications. Fa Yi Xue Za Zhi (2014) 0.75
Discovery and SAR of orally efficacious tetrahydropyridopyridazinone PARP inhibitors for the treatment of cancer. Bioorg Med Chem (2012) 0.75
[Research of repairing rabbit knee joint cartilage defect by compound material of fibrin glue and decalcified bone matrix (DBM) and chondrocytes]. Zhongguo Gu Shang (2009) 0.75
[Fast analytical method on content and transfer rate of marker component in ethanol precipitation of cinobufacini by near infrared spectroscopy]. Zhongguo Zhong Yao Za Zhi (2011) 0.75
In-line monitoring of extraction process of scutellarein from Erigeron breviscapus (vant.) Hand-Mazz based on qualitative and quantitative uses of near-infrared spectroscopy. Spectrochim Acta A Mol Biomol Spectrosc (2011) 0.75
Mature teratoma in cerebellopontine angle in a 70-year-old female: a rare tumor with exceptional location, age, and presentation. Neurol India (2013) 0.75
Orthogonal array design for the optimization of supercritical fluid extraction of tanshinones from Danshen. J Sep Sci (2008) 0.75
Diaphragmatic tear in pregnancy induced by intractable vomiting: a case report and review of the literature. J Matern Fetal Neonatal Med (2011) 0.75
Meningeal melanocytoma of the middle cranial fossa (the Meckel's cave). Neurol India (2015) 0.75
[Effect of prone position ventilation on respiratory mechanics and prognosis in patients with acute respiratory distress syndrome concurrent with interstitial lung disease]. Zhonghua Wei Zhong Bing Ji Jiu Yi Xue (2015) 0.75
[Treatment type C fracture of the distal radius with locking compression plate and external fixators]. Zhongguo Gu Shang (2013) 0.75
Experimental study on the subthreshold swing of silicon nanowire transistors. J Nanosci Nanotechnol (2010) 0.75
[Preparation of monoclonal antibodies against flagellin core protein of Vibrio parahaemolyticus and its activity analysis]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi (2013) 0.75
Dual-core antiresonant hollow core fibers. Opt Express (2016) 0.75
Low-temperature performance of accumulation-mode p-channel wrap-gated FinFETs. J Nanosci Nanotechnol (2013) 0.75
Generation and evaluation of mammalian secreted and membrane protein expression libraries for high-throughput target discovery. Protein Expr Purif (2011) 0.75