Published in Am J Clin Pathol on June 01, 2006
Incorporation of somatic BRAF mutation testing into an algorithm for the investigation of hereditary non-polyposis colorectal cancer. Fam Cancer (2007) 1.77
Endometrial tumour BRAF mutations and MLH1 promoter methylation as predictors of germline mismatch repair gene mutation status: a literature review. Fam Cancer (2014) 0.87
The gray area between heritable and cancer somatic (tumor phenotype) molecular genetic testing of colorectal adenocarcinomas. Am J Clin Pathol (2006) 0.77
Prognostic role of KRAS and BRAF in stage II and III resected colon cancer: results of the translational study on the PETACC-3, EORTC 40993, SAKK 60-00 trial. J Clin Oncol (2009) 7.04
Immunohistochemical expression of endothelial markers CD31, CD34, von Willebrand factor, and Fli-1 in normal human tissues. J Histochem Cytochem (2005) 3.43
Histologic grade, but not SYT-SSX fusion type, is an important prognostic factor in patients with synovial sarcoma: a multicenter, retrospective analysis. J Clin Oncol (2004) 3.28
Integrated analysis of molecular and clinical prognostic factors in stage II/III colon cancer. J Natl Cancer Inst (2012) 2.49
Tissue engineered fetal skin constructs for paediatric burns. Lancet (2005) 1.92
Extended co-expression of inhibitory receptors by human CD8 T-cells depending on differentiation, antigen-specificity and anatomical localization. PLoS One (2012) 1.77
Prognostic and predictive biomarkers in resected colon cancer: current status and future perspectives for integrating genomics into biomarker discovery. Oncologist (2010) 1.72
Gene expression patterns unveil a new level of molecular heterogeneity in colorectal cancer. J Pathol (2013) 1.71
Hypermethylation of the human telomerase catalytic subunit (hTERT) gene correlates with telomerase activity. Int J Cancer (2002) 1.64
Translocation-positive low-grade fibromyxoid sarcoma: clinicopathologic and molecular analysis of a series expanding the morphologic spectrum and suggesting potential relationship to sclerosing epithelioid fibrosarcoma: a study from the French Sarcoma Group. Am J Surg Pathol (2007) 1.63
Importance of tumor regression assessment in predicting the outcome in patients with locally advanced rectal carcinoma who are treated with preoperative radiotherapy. Cancer (2002) 1.60
Efficiency of recombinant human TNF in human cancer therapy. Cancer Immun (2006) 1.58
Early prediction of response to sunitinib after imatinib failure by 18F-fluorodeoxyglucose positron emission tomography in patients with gastrointestinal stromal tumor. J Clin Oncol (2008) 1.50
Evolution of intratumoral genetic heterogeneity during colorectal cancer progression. Carcinogenesis (2005) 1.45
The role of the pathologist in tissue banking: European Consensus Expert Group Report. Virchows Arch (2010) 1.44
Effect of timing of surgery on survival after preoperative hyperfractionated accelerated radiotherapy (HART) for locally advanced rectal cancer (LARC): is it a matter of days? Acta Oncol (2006) 1.43
p16 inactivation by methylation of the CDKN2A promoter occurs early during neoplastic progression in Barrett's esophagus. Gastroenterology (2002) 1.38
Small cell lung cancer: state of the art and future perspectives. Lung Cancer (2004) 1.37
Engineering a high-affinity methyl-CpG-binding protein. Nucleic Acids Res (2006) 1.36
Expression of NDRG1, a differentiation-related gene, in human tissues. Histochem Cell Biol (2002) 1.32
CTCF binds the proximal exonic region of hTERT and inhibits its transcription. Nucleic Acids Res (2005) 1.27
Demethylation of the human telomerase catalytic subunit (hTERT) gene promoter reduced hTERT expression and telomerase activity and shortened telomeres. Exp Cell Res (2003) 1.23
Expression of the CTCF-paralogous cancer-testis gene, brother of the regulator of imprinted sites (BORIS), is regulated by three alternative promoters modulated by CpG methylation and by CTCF and p53 transcription factors. Nucleic Acids Res (2007) 1.23
Systemic investigation of keratoepithelin deposits in TGFBI/BIGH3-related corneal dystrophy. Mol Vis (2006) 1.19
Serrated polyps of the colorectum: is sessile serrated adenoma distinguishable from hyperplastic polyp in a daily practice? Virchows Arch (2007) 1.15
Methylation of APC, TIMP3, and TERT: a new predictive marker to distinguish Barrett's oesophagus patients at risk for malignant transformation. J Pathol (2006) 1.12
Serrated polyps of the large intestine: a molecular study comparing sessile serrated adenomas and hyperplastic polyps. Histopathology (2009) 1.11
Loss of Smad4 expression predicts liver metastasis in human colorectal cancer. Oncol Rep (2007) 1.09
Immunohistochemical localization of hTERT protein in human tissues. Histochem Cell Biol (2004) 1.09
BORIS/CTCFL-mediated transcriptional regulation of the hTERT telomerase gene in testicular and ovarian tumor cells. Nucleic Acids Res (2010) 1.04
Beta amyloid and hyperphosphorylated tau deposits in the pancreas in type 2 diabetes. Neurobiol Aging (2008) 1.03
Unusual distribution of DNA methylation within the hTERT CpG island in tissues and cell lines. Biochem Biophys Res Commun (2004) 1.02
Multicentre validation study of nucleic acids extraction from FFPE tissues. Virchows Arch (2010) 1.01
Pattern and clinical significance of cancer-testis gene expression in head and neck squamous cell carcinoma. Int J Cancer (2010) 1.01
Selection of patients with germline MLH1 mutated Lynch syndrome by determination of MLH1 methylation and BRAF mutation. Fam Cancer (2010) 1.00
Microsatellite instability, prognosis and drug sensitivity of stage II and III colorectal cancer: more complexity to the puzzle. J Natl Cancer Inst (2011) 0.99
Impact of genomic methylation on radiation sensitivity of colorectal carcinoma. Int J Radiat Oncol Biol Phys (2010) 0.99
Vaccination-induced functional competence of circulating human tumor-specific CD8 T-cells. Int J Cancer (2011) 0.99
Naturally acquired MAGE-A10- and SSX-2-specific CD8+ T cell responses in patients with hepatocellular carcinoma. J Immunol (2005) 0.99
Comparison of microsatellite instability and chromosomal instability in predicting survival of patients with T3N0 colorectal cancer. Surgery (2002) 0.98
Medicolegal liability in pathology: an international perspective. Semin Diagn Pathol (2007) 0.98
The human telomerase RNA gene (hTERC) is regulated during carcinogenesis but is not dependent on DNA methylation. Carcinogenesis (2002) 0.94
Beta-catenin expression and its association with prognostic factors in adenocarcinoma developed in Barrett esophagus. Am J Clin Pathol (2002) 0.93
Epigenetic alteration of the Wnt inhibitory factor-1 promoter occurs early in the carcinogenesis of Barrett's esophagus. Cancer Sci (2007) 0.93
Telomerase activity and hTERT mRNA expression can be heterogeneous and does not correlate with telomere length in soft tissue sarcomas. Int J Cancer (2002) 0.93
Monoallelic methylation of the APC promoter is altered in normal gastric mucosa associated with neoplastic lesions. Cancer Res (2004) 0.93
Human melanoma-specific CD8(+) T-cells from metastases are capable of antigen-specific degranulation and cytolysis directly ex vivo. Oncoimmunology (2012) 0.92
Serrated polyps of the colon: how reproducible is their classification? Virchows Arch (2012) 0.91
An agarose matrix facilitates sectioning of tissue microarray blocks. J Histochem Cytochem (2006) 0.91
Kayexalate Intake (in Sorbitol) and Jejunal Diverticulitis, a Causative Role or an Innocent Bystander? Case Rep Gastroenterol (2007) 0.91
Targeting the Wnt signaling pathway to treat Barrett's esophagus. Expert Opin Ther Targets (2007) 0.89
Implication of the exon region in the regulation of the human telomerase reverse transcriptase gene promoter. Biochem Biophys Res Commun (2003) 0.89
Contribution of IgH-PCR to the evaluation of B-cell lymphoma involvement in paraffin-embedded bone marrow biopsy specimens. Am J Clin Pathol (2003) 0.89
Tumor budding in colorectal cancer revisited: results of a multicenter interobserver study. Virchows Arch (2015) 0.88
p16(INK4a) -mediated suppression of telomerase in normal and malignant human breast cells. Aging Cell (2010) 0.88
Methylation of the hTERT promoter: a novel cancer biomarker for leptomeningeal metastasis detection in cerebrospinal fluids. Clin Cancer Res (2013) 0.87
Imprinting of tumor-suppressor genes in human placenta. Epigenetics (2009) 0.87
PAX5 activates the transcription of the human telomerase reverse transcriptase gene in B cells. J Pathol (2010) 0.87
Specific association between the methyl-CpG-binding domain protein 2 and the hypermethylated region of the human telomerase reverse transcriptase promoter in cancer cells. Carcinogenesis (2008) 0.87
Monoamine oxidase A down-regulation contributes to high metanephrine concentration in pheochromocytoma. J Clin Endocrinol Metab (2012) 0.87
Superficial primitive Ewing's sarcoma: a clinicopathologic and molecular cytogenetic analysis of 14 cases. Mod Pathol (2008) 0.86
MBD2-mediated transcriptional repression of the p14ARF tumor suppressor gene in human colon cancer cells. Pathobiology (2008) 0.86
Lymphocoele: a rare and little known complication of anterior lumbar surgery. Eur Spine J (2009) 0.85
Heterogeneity of human glioblastoma: glutathione-S-transferase and methylguanine-methyltransferase. Cancer Invest (2008) 0.85
Simple appendicitis? Can J Surg (2008) 0.85
A multicenter study to validate the reproducibility of MSI testing with a panel of 5 quasimonomorphic mononucleotide repeats. Diagn Mol Pathol (2010) 0.85
Background staining of visualization systems in immunohistochemistry: comparison of the Avidin-Biotin Complex system and the EnVision+ system. Appl Immunohistochem Mol Morphol (2007) 0.85
EBV+ cutaneous B-cell lymphoproliferation of the leg in an elderly patient with mycosis fungoides and methotrexate treatment. APMIS (2012) 0.85
Sentinel lymph node biopsy in nonmelanoma skin cancer patients. J Skin Cancer (2013) 0.84
Tenascin-W, a new marker of cancer stroma, is elevated in sera of colon and breast cancer patients. Int J Cancer (2008) 0.84
Isolated limb perfusion with tumor necrosis factor and melphalan for non-resectable soft tissue sarcomas: long-term results on efficacy and limb salvage in a selected group of patients. J Surg Oncol (2008) 0.84
Predictive factors in locally advanced rectal cancer treated with preoperative hyperfractionated and accelerated radiotherapy. Hum Pathol (2003) 0.83
Preferential binding of the methyl-CpG binding domain protein 2 at methylated transcriptional start site regions. Epigenetics (2011) 0.83
The role of COX-2 in rectal cancer treated with preoperative radiotherapy. Virchows Arch (2008) 0.82
Intraneural synovial sarcoma: two cases. Mod Pathol (2004) 0.82
Molecular detection of the synovial sarcoma translocation t(X;18) by real-time polymerase chain reaction in paraffin-embedded material. Diagn Mol Pathol (2002) 0.81
Malignant peripheral nerve sheath tumors are t(X;18)-negative sarcomas. Molecular analysis of 25 cases occurring in neurofibromatosis type 1 patients, using two different RT-PCR-based methods of detection. Mod Pathol (2002) 0.81
The educational benefits of a multihead microscope in an academic hospital. Med Teach (2008) 0.80
Malakoplakia and colonic adenoma: a rare association. Ann Diagn Pathol (2004) 0.80
Preoperative hyper-fractionated accelerated radiotherapy (HART) in locally advanced rectal cancer (LARC) immediately followed by surgery. A prospective phase II trial. Radiother Oncol (2006) 0.80
Diagnosis and workup of 522 consecutive patients with neuroendocrine neoplasms in Switzerland. Swiss Med Wkly (2014) 0.79
hTERT methylation is necessary but not sufficient for telomerase activity in colorectal cells. Oncol Lett (2011) 0.79
Assessment of K-ras, Smad4 and p53 gene alterations in colorectal metastases and their role in the metastatic process. Oncol Rep (2004) 0.79
Preoperative hyperfractionated accelerated radiotherapy (HART) and concomitant CPT-11 in locally advanced rectal carcinoma: a phase I study. Int J Radiat Oncol Biol Phys (2003) 0.78
Microscopes and computers in small-group pathology learning. Med Educ (2006) 0.78
Early occurrence of lung adenocarcinoma and breast cancer after radiotherapy of a chest wall sarcoma in a patient with a de novo germline mutation in TP53. Fam Cancer (2011) 0.78
Small intestine without mucosa as a growing vascular conduit: a porcine experimental study. J Thorac Cardiovasc Surg (2002) 0.78
Detection of micrometastases in sentinel lymph nodes from melanoma patients: direct comparison of multimarker molecular and immunopathological methods. Melanoma Res (2003) 0.78
Risk-adjusted rates for potentially avoidable reoperations were computed from routine hospital data. J Clin Epidemiol (2006) 0.77
Efficacy and safety of universal valganciclovir prophylaxis combined with a tacrolimus/mycophenolate-based regimen in kidney transplantation. Swiss Med Wkly (2007) 0.77
An unusual case of metastatic melanoma sensitive to chemotherapy and immunotherapy, with late immune escape in the brain. Cancer Immun (2008) 0.77
Measurement of the whole body clearance of infused glycerol as a test of liver function after major hepatectomy. Clin Physiol Funct Imaging (2002) 0.77
Role of metallothioneins in irradiated human rectal carcinoma. Cancer (2002) 0.77
Radiation-associated synovial sarcoma: clinicopathologic and molecular analysis of two cases. Mod Pathol (2002) 0.77
SYT-SSX fusion is absent in sarcomatoid mesothelioma allowing its distinction from synovial sarcoma of the pleura. Mod Pathol (2007) 0.76