Published in Biochem Biophys Res Commun on May 04, 2006
ALK5- and TGFBR2-independent role of ALK1 in the pathogenesis of hereditary hemorrhagic telangiectasia type 2. Blood (2007) 2.17
Time-dependent patterning of the mesoderm and endoderm by Nodal signals in zebrafish. BMC Dev Biol (2007) 1.16
Two highly related regulatory subunits of PP2A exert opposite effects on TGF-beta/Activin/Nodal signalling. Development (2008) 1.11
Transforming growth factor: beta signaling is essential for limb regeneration in axolotls. PLoS One (2007) 1.06
The germ cell nuclear proteins hnRNP G-T and RBMY activate a testis-specific exon. PLoS Genet (2009) 1.03
Global identification of SMAD2 target genes reveals a role for multiple co-regulatory factors in zebrafish early gastrulas. J Biol Chem (2011) 0.93
Mesendodermal signals required for otic induction: Bmp-antagonists cooperate with Fgf and can facilitate formation of ectopic otic tissue. Dev Dyn (2009) 0.92
The stress-response gene redd1 regulates dorsoventral patterning by antagonizing Wnt/β-catenin activity in zebrafish. PLoS One (2012) 0.89
Churchill regulates cell movement and mesoderm specification by repressing Nodal signaling. BMC Dev Biol (2007) 0.84
A 190 base pair, TGF-β responsive tooth and fin enhancer is required for stickleback Bmp6 expression. Dev Biol (2015) 0.83
Stimulation of hepatocarcinogenesis by neutrophils upon induction of oncogenic kras expression in transgenic zebrafish. J Hepatol (2015) 0.80
Correct anteroposterior patterning of the zebrafish neurectoderm in the absence of the early dorsal organizer. BMC Dev Biol (2011) 0.80
Keeping a lid on nodal: transcriptional and translational repression of nodal signalling. Open Biol (2016) 0.78
Perineurial Glial Plasticity and the Role of TGF-β in the Development of the Blood-Nerve Barrier. J Neurosci (2017) 0.75
Fscn1 is required for the trafficking of TGF-β family type I receptors during endoderm formation. Nat Commun (2016) 0.75
Utility of Lymphoblastoid Cell Lines for Induced Pluripotent Stem Cell Generation. Stem Cells Int (2016) 0.75
Temporal and spatial requirements for Nodal-induced anterior mesendoderm and mesoderm in anterior neurulation. Genesis (2016) 0.75
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine. Nat Biotechnol (2010) 9.01
Base-resolution analysis of 5-hydroxymethylcytosine in the mammalian genome. Cell (2012) 7.09
Serum microRNA signatures identified in a genome-wide serum microRNA expression profiling predict survival of non-small-cell lung cancer. J Clin Oncol (2010) 5.92
PPM1A functions as a Smad phosphatase to terminate TGFbeta signaling. Cell (2006) 5.28
5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging. Nat Neurosci (2011) 4.15
Single nucleotide polymorphism associated with mature miR-125a alters the processing of pri-miRNA. Hum Mol Genet (2007) 4.08
Microenvironment determines lineage fate in a human model of MLL-AF9 leukemia. Cancer Cell (2008) 3.79
Genetic variants of miRNA sequences and non-small cell lung cancer survival. J Clin Invest (2008) 3.53
Dishevelled: The hub of Wnt signaling. Cell Signal (2009) 3.31
RNA-binding proteins hnRNP A2/B1 and CUGBP1 suppress fragile X CGG premutation repeat-induced neurodegeneration in a Drosophila model of FXTAS. Neuron (2007) 3.30
Cross talk between microRNA and epigenetic regulation in adult neurogenesis. J Cell Biol (2010) 3.16
Genome-wide profiling of 5-formylcytosine reveals its roles in epigenetic priming. Cell (2013) 3.13
MicroRNA miR-137 regulates neuronal maturation by targeting ubiquitin ligase mind bomb-1. Stem Cells (2010) 2.89
Integrating 5-hydroxymethylcytosine into the epigenomic landscape of human embryonic stem cells. PLoS Genet (2011) 2.87
Epidermal injury and infection during poxvirus immunization is crucial for the generation of highly protective T cell-mediated immunity. Nat Med (2010) 2.61
Common genetic variants in pre-microRNAs were associated with increased risk of breast cancer in Chinese women. Hum Mutat (2009) 2.60
MicroRNA miR-24 inhibits erythropoiesis by targeting activin type I receptor ALK4. Blood (2007) 2.40
Phosphoglycerate mutase 1 coordinates glycolysis and biosynthesis to promote tumor growth. Cancer Cell (2012) 2.39
Autophagy negatively regulates Wnt signalling by promoting Dishevelled degradation. Nat Cell Biol (2010) 2.37
Expanded GGGGCC repeat RNA associated with amyotrophic lateral sclerosis and frontotemporal dementia causes neurodegeneration. Proc Natl Acad Sci U S A (2013) 2.30
Endothelial Smad4 maintains cerebrovascular integrity by activating N-cadherin through cooperation with Notch. Dev Cell (2011) 2.17
Identification of small molecules rescuing fragile X syndrome phenotypes in Drosophila. Nat Chem Biol (2008) 2.04
Dynamic programming of CD8+ T cell trafficking after live viral immunization. Immunity (2006) 1.98
Functional variant in microRNA-196a2 contributes to the susceptibility of congenital heart disease in a Chinese population. Hum Mutat (2009) 1.90
Epigenetic regulation of miR-184 by MBD1 governs neural stem cell proliferation and differentiation. Cell Stem Cell (2010) 1.86
A small molecule enhances RNA interference and promotes microRNA processing. Nat Biotechnol (2008) 1.80
Fragile x mental retardation protein regulates proliferation and differentiation of adult neural stem/progenitor cells. PLoS Genet (2010) 1.77
Dapper 1 antagonizes Wnt signaling by promoting dishevelled degradation. J Biol Chem (2006) 1.70
MCP-1 mediates TGF-beta-induced angiogenesis by stimulating vascular smooth muscle cell migration. Blood (2006) 1.68
Smad7 antagonizes transforming growth factor beta signaling in the nucleus by interfering with functional Smad-DNA complex formation. Mol Cell Biol (2007) 1.68
Roles of small regulatory RNAs in determining neuronal identity. Nat Rev Neurosci (2010) 1.68
Direct differentiation of atrial and ventricular myocytes from human embryonic stem cells by alternating retinoid signals. Cell Res (2010) 1.67
Tet-assisted bisulfite sequencing of 5-hydroxymethylcytosine. Nat Protoc (2012) 1.66
An invasive podosome-like structure promotes fusion pore formation during myoblast fusion. J Cell Biol (2010) 1.59
Chemokine receptor CXCR7 regulates the invasion, angiogenesis and tumor growth of human hepatocellular carcinoma cells. J Exp Clin Cancer Res (2010) 1.59
Localization of Rac2 via the C terminus and aspartic acid 150 specifies superoxide generation, actin polarity and chemotaxis in neutrophils. Nat Immunol (2004) 1.56
Tailoring the performances of low operating voltage InAlAs/InGaAs avalanche photodetectors. Opt Express (2015) 1.52
Common genetic variants on 5p15.33 contribute to risk of lung adenocarcinoma in a Chinese population. Carcinogenesis (2009) 1.48
Ablation of Fmrp in adult neural stem cells disrupts hippocampus-dependent learning. Nat Med (2011) 1.47
Argonaute 1 regulates the fate of germline stem cells in Drosophila. Development (2007) 1.47
Axin is a scaffold protein in TGF-beta signaling that promotes degradation of Smad7 by Arkadia. EMBO J (2006) 1.47
Smad7: not only a regulator, but also a cross-talk mediator of TGF-β signalling. Biochem J (2011) 1.46
Functional genetic variations in cytotoxic T-lymphocyte antigen 4 and susceptibility to multiple types of cancer. Cancer Res (2008) 1.39
Physiological identification of human transcripts translationally regulated by a specific microRNA. Hum Mol Genet (2005) 1.39
Follistatin-like 1 (Fstl1) is a bone morphogenetic protein (BMP) 4 signaling antagonist in controlling mouse lung development. Proc Natl Acad Sci U S A (2011) 1.34
The Fused/Smurf complex controls the fate of Drosophila germline stem cells by generating a gradient BMP response. Cell (2010) 1.34
Identification of the proliferation/differentiation switch in the cellular network of multicellular organisms. PLoS Comput Biol (2006) 1.32
Zebrafish Dpr2 inhibits mesoderm induction by promoting degradation of nodal receptors. Science (2004) 1.31
Sp1-like transcription factors are regulators of embryonic development in vertebrates. Dev Growth Differ (2005) 1.31
BMP4 Signaling Acts via dual-specificity phosphatase 9 to control ERK activity in mouse embryonic stem cells. Cell Stem Cell (2012) 1.29
Human BAMBI cooperates with Smad7 to inhibit transforming growth factor-beta signaling. J Biol Chem (2009) 1.29
Subtelomeric hotspots of aberrant 5-hydroxymethylcytosine-mediated epigenetic modifications during reprogramming to pluripotency. Nat Cell Biol (2013) 1.27
Genome-wide mapping of SMAD target genes reveals the role of BMP signaling in embryonic stem cell fate determination. Genome Res (2009) 1.27
Dapper1 is a nucleocytoplasmic shuttling protein that negatively modulates Wnt signaling in the nucleus. J Biol Chem (2008) 1.26
Gambogic amide, a selective agonist for TrkA receptor that possesses robust neurotrophic activity, prevents neuronal cell death. Proc Natl Acad Sci U S A (2007) 1.24
U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer's disease. Proc Natl Acad Sci U S A (2013) 1.23
The loss of methyl-CpG binding protein 1 leads to autism-like behavioral deficits. Hum Mol Genet (2008) 1.23
Six1 promotes proliferation of pancreatic cancer cells via upregulation of cyclin D1 expression. PLoS One (2013) 1.23
Transforming growth factor beta activates Smad2 in the absence of receptor endocytosis. J Biol Chem (2002) 1.22
Actin-propelled invasive membrane protrusions promote fusogenic protein engagement during cell-cell fusion. Science (2013) 1.21
The bantam microRNA is associated with drosophila fragile X mental retardation protein and regulates the fate of germline stem cells. PLoS Genet (2009) 1.21
Genome-wide DNA hydroxymethylation changes are associated with neurodevelopmental genes in the developing human cerebellum. Hum Mol Genet (2012) 1.21
Phenotypes and genotypes of insulin-like growth factor 1, IGF-binding protein-3 and cancer risk: evidence from 96 studies. Eur J Hum Genet (2009) 1.20
TET1 plays an essential oncogenic role in MLL-rearranged leukemia. Proc Natl Acad Sci U S A (2013) 1.19
Tob1 controls dorsal development of zebrafish embryos by antagonizing maternal beta-catenin transcriptional activity. Dev Cell (2006) 1.19
Specific activation of mitogen-activated protein kinase by transforming growth factor-beta receptors in lipid rafts is required for epithelial cell plasticity. Mol Biol Cell (2008) 1.18
RNA-Seq analyses generate comprehensive transcriptomic landscape and reveal complex transcript patterns in hepatocellular carcinoma. PLoS One (2011) 1.18
Tob genes in development and homeostasis. Dev Dyn (2007) 1.17
Loss of Dact1 disrupts planar cell polarity signaling by altering dishevelled activity and leads to posterior malformation in mice. J Biol Chem (2010) 1.17
Neuronal morphogenesis is regulated by the interplay between cyclin-dependent kinase 5 and the ubiquitin ligase mind bomb 1. J Neurosci (2007) 1.17
A beta-catenin-independent dorsalization pathway activated by Axin/JNK signaling and antagonized by aida. Dev Cell (2007) 1.16
Human microRNA (miR29b) expression controls the amount of branched chain alpha-ketoacid dehydrogenase complex in a cell. Hum Mol Genet (2005) 1.16
Fragile X protein functions with lgl and the par complex in flies and mice. Dev Cell (2005) 1.14
Single-molecule imaging reveals transforming growth factor-beta-induced type II receptor dimerization. Proc Natl Acad Sci U S A (2009) 1.14
Dynamics of DNA methylation in aging and Alzheimer's disease. DNA Cell Biol (2012) 1.13
Cross-talk between RhoH and Rac1 in regulation of actin cytoskeleton and chemotaxis of hematopoietic progenitor cells. Blood (2007) 1.13
Enhanced apoptosis and tumor growth suppression elicited by combination of MEK (selumetinib) and mTOR kinase inhibitors (AZD8055). Cancer Res (2012) 1.12
The evolutionally conserved activity of Dapper2 in antagonizing TGF-beta signaling. FASEB J (2006) 1.11
PKCλ is critical in AMPA receptor phosphorylation and synaptic incorporation during LTP. EMBO J (2013) 1.10
Chiral Brønsted acid-catalyzed direct asymmetric Mannich reaction. J Am Chem Soc (2007) 1.10
XBP1 mRNA splicing triggers an autophagic response in endothelial cells through BECLIN-1 transcriptional activation. J Biol Chem (2012) 1.09
A genomewide survey of homeobox genes and identification of novel structure of the Hox cluster in the silkworm, Bombyx mori. Insect Biochem Mol Biol (2008) 1.09
Tyr26 phosphorylation of PGAM1 provides a metabolic advantage to tumours by stabilizing the active conformation. Nat Commun (2013) 1.08
c-Cbl-mediated neddylation antagonizes ubiquitination and degradation of the TGF-β type II receptor. Mol Cell (2013) 1.08
Regulation of TGF-β receptor activity. Cell Biosci (2012) 1.07
Distinct regulation of gene expression in human endothelial cells by TGF-beta and its receptors. Microvasc Res (2006) 1.07
PPM1A Functions as a Smad Phosphatase to Terminate TGFβ Signaling. Cell (2016) 1.07
Amotl2 is essential for cell movements in zebrafish embryo and regulates c-Src translocation. Development (2007) 1.07
Tumorigenic role of podoplanin in esophageal squamous-cell carcinoma. Ann Surg Oncol (2010) 1.05
β-Catenin 1 and β-catenin 2 play similar and distinct roles in left-right asymmetric development of zebrafish embryos. Development (2012) 1.05
RNA-binding protein FXR2 regulates adult hippocampal neurogenesis by reducing Noggin expression. Neuron (2011) 1.05