Published in J Exp Biol on June 01, 2006
AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha. Proc Natl Acad Sci U S A (2007) 8.23
The role of exercise and PGC1alpha in inflammation and chronic disease. Nature (2008) 5.31
Survival in critical illness is associated with early activation of mitochondrial biogenesis. Am J Respir Crit Care Med (2010) 2.48
MitoNEET is an iron-containing outer mitochondrial membrane protein that regulates oxidative capacity. Proc Natl Acad Sci U S A (2007) 2.28
A practical model of low-volume high-intensity interval training induces mitochondrial biogenesis in human skeletal muscle: potential mechanisms. J Physiol (2010) 2.28
Global transcript profiles of fat in monozygotic twins discordant for BMI: pathways behind acquired obesity. PLoS Med (2008) 1.94
Deficiency of electron transport chain in human skeletal muscle mitochondria in type 2 diabetes mellitus and obesity. Am J Physiol Endocrinol Metab (2009) 1.59
DNA extraction procedures meaningfully influence qPCR-based mtDNA copy number determination. Mitochondrion (2009) 1.50
Diet, exercise or diet with exercise: comparing the effectiveness of treatment options for weight-loss and changes in fitness for adults (18-65 years old) who are overfat, or obese; systematic review and meta-analysis. J Diabetes Metab Disord (2015) 1.47
Mitochondrial antioxidative capacity regulates muscle glucose uptake in the conscious mouse: effect of exercise and diet. J Appl Physiol (1985) (2012) 1.43
Nitric oxide inhibition of Drp1-mediated mitochondrial fission is critical for myogenic differentiation. Cell Death Differ (2010) 1.35
Skeletal muscle mitochondria and aging: a review. J Aging Res (2012) 1.27
Repeated bouts of aerobic exercise lead to reductions in skeletal muscle free radical generation and nuclear factor kappaB activation. J Physiol (2008) 1.24
Reactive oxygen species in skeletal muscle signaling. J Signal Transduct (2011) 1.23
Muscle oxidative capacity during IL-6-dependent cancer cachexia. Am J Physiol Regul Integr Comp Physiol (2010) 1.19
Oxidative stress, molecular inflammation and sarcopenia. Int J Mol Sci (2010) 1.17
The role of muscle insulin resistance in the pathogenesis of atherogenic dyslipidemia and nonalcoholic fatty liver disease associated with the metabolic syndrome. Annu Rev Nutr (2010) 1.15
VEGF stimulation of mitochondrial biogenesis: requirement of AKT3 kinase. FASEB J (2008) 1.14
Reactive oxygen species: impact on skeletal muscle. Compr Physiol (2011) 1.14
Low intrinsic running capacity is associated with reduced skeletal muscle substrate oxidation and lower mitochondrial content in white skeletal muscle. Am J Physiol Regul Integr Comp Physiol (2011) 1.11
Acute exercise remodels mitochondrial membrane interactions in mouse skeletal muscle. J Appl Physiol (1985) (2013) 1.10
NOS isoform-specific regulation of basal but not exercise-induced mitochondrial biogenesis in mouse skeletal muscle. J Physiol (2007) 1.05
Mitochondrial pathways in sarcopenia of aging and disuse muscle atrophy. Biol Chem (2013) 1.04
Delayed recovery of skeletal muscle mass following hindlimb immobilization in mTOR heterozygous mice. PLoS One (2012) 1.02
Age associated low mitochondrial biogenesis may be explained by lack of response of PGC-1α to exercise training. Age (Dordr) (2011) 1.02
Impaired muscle AMPK activation in the metabolic syndrome may attenuate improved insulin action after exercise training. J Clin Endocrinol Metab (2011) 1.02
Age-associated declines in mitochondrial biogenesis and protein quality control factors are minimized by exercise training. Am J Physiol Regul Integr Comp Physiol (2012) 1.02
Electrical pulse stimulation of cultured human skeletal muscle cells as an in vitro model of exercise. PLoS One (2012) 1.00
Carbon monoxide, skeletal muscle oxidative stress, and mitochondrial biogenesis in humans. Am J Physiol Heart Circ Physiol (2009) 0.99
Targeting the mitochondria to augment myocardial protection. Curr Opin Pharmacol (2008) 0.97
Effect of endurance exercise training on Ca2+ calmodulin-dependent protein kinase II expression and signalling in skeletal muscle of humans. J Physiol (2007) 0.97
Morphofunctional and Biochemical Approaches for Studying Mitochondrial Changes during Myoblasts Differentiation. J Aging Res (2011) 0.96
Successive bouts of cycling stimulates genes associated with mitochondrial biogenesis. Eur J Appl Physiol (2009) 0.95
Time course analysis reveals gene-specific transcript and protein kinetics of adaptation to short-term aerobic exercise training in human skeletal muscle. PLoS One (2013) 0.94
Electric pulse stimulation of cultured murine muscle cells reproduces gene expression changes of trained mouse muscle. PLoS One (2010) 0.93
Mitochondria as a potential regulator of myogenesis. ScientificWorldJournal (2013) 0.92
Lactate administration reproduces specific brain and liver exercise-related changes. J Neurochem (2013) 0.92
Systems analysis of biological networks in skeletal muscle function. Wiley Interdiscip Rev Syst Biol Med (2012) 0.90
Potential mechanisms of muscle mitochondrial dysfunction in aging and obesity and cellular consequences. Int J Mol Sci (2009) 0.89
Temporal and spatial patterns of gene expression in skeletal muscles in response to swim training in adult zebrafish (Danio rerio). J Comp Physiol B (2009) 0.87
Molecular basis for an attenuated mitochondrial adaptive plasticity in aged skeletal muscle. Aging (Albany NY) (2009) 0.86
Exercise training, energy metabolism, and heart failure. Appl Physiol Nutr Metab (2009) 0.86
Overexpression of PGC-1α increases fatty acid oxidative capacity of human skeletal muscle cells. Biochem Res Int (2011) 0.86
Lower prevalence of hypertension, hypercholesterolemia, and diabetes in marathoners. Med Sci Sports Exerc (2009) 0.86
Developmental origins of obesity: programming of food intake or physical activity? Adv Exp Med Biol (2009) 0.85
The formation and functional consequences of heterogeneous mitochondrial distributions in skeletal muscle. J Exp Biol (2012) 0.85
Tissue-specific changes in fatty acid oxidation in hypoxic heart and skeletal muscle. Am J Physiol Regul Integr Comp Physiol (2013) 0.85
An overview of the contribution of fatness and fitness factors, and the role of exercise, in the formation of health status for individuals who are overweight. J Diabetes Metab Disord (2012) 0.84
Alterations in peroxisome proliferator-activated receptor mRNA expression in skeletal muscle after acute and repeated bouts of exercise. Mol Cell Biochem (2009) 0.84
Mitochondrial haplotype divergences affect specific temperature sensitivity of mitochondrial respiration. J Bioenerg Biomembr (2012) 0.81
Cachectic skeletal muscle response to a novel bout of low-frequency stimulation. J Appl Physiol (1985) (2014) 0.81
Muscle transcriptome adaptations with mild eccentric ergometer exercise. Pflugers Arch (2007) 0.81
Regulation of PPARγ Coactivator-1α Function and Expression in Muscle: Effect of Exercise. PPAR Res (2010) 0.80
Effect of chronic contractile activity on mRNA stability in skeletal muscle. Am J Physiol Cell Physiol (2010) 0.80
An imbalance in C/EBPs and increased mitochondrial activity in asthmatic airway smooth muscle cells: novel targets in asthma therapy? Br J Pharmacol (2009) 0.80
To perform your best: work hard not long. J Physiol (2006) 0.79
Persistence of motor unit and muscle fiber types in the presence of inactivity. J Exp Biol (2008) 0.79
Physical exercise associated with NO production: signaling pathways and significance in health and disease. Front Cell Dev Biol (2015) 0.78
Changes of myogenic reactive oxygen species and interleukin-6 in contracting skeletal muscle cells. Oxid Med Cell Longev (2012) 0.78
Mitochondrial function in physically active elders with sarcopenia. Mech Ageing Dev (2009) 0.77
The emerging role of skeletal muscle oxidative metabolism as a biological target and cellular regulator of cancer-induced muscle wasting. Semin Cell Dev Biol (2015) 0.77
The HO-1/CO system regulates mitochondrial-capillary density relationships in human skeletal muscle. Am J Physiol Lung Cell Mol Physiol (2015) 0.77
Subproteomic analysis of basic proteins in aged skeletal muscle following offgel pre-fractionation. Mol Med Rep (2012) 0.77
Role of exercise duration on metabolic adaptations in working muscle to short-term moderate-to-heavy aerobic-based cycle training. Eur J Appl Physiol (2013) 0.76
Specific Intensity for Peaking: Is Race Pace the Best Option? Asian J Sports Med (2015) 0.75
Optimizing intramuscular adaptations to aerobic exercise: effects of carbohydrate restriction and protein supplementation on mitochondrial biogenesis. Adv Nutr (2013) 0.75
Oxygen control of intracellular distribution of mitochondria in muscle fibers. Biotechnol Bioeng (2013) 0.75
Mitochondrial co-chaperone protein Tid1 is required for energy homeostasis during skeletal myogenesis. Stem Cell Res Ther (2016) 0.75
Effect of eight weeks of quercetin supplementation on exercise performance, muscle damage and body muscle in male badminton players. Int J Prev Med (2013) 0.75
Improvement Characteristics of Bio-active Materials Coated Fabric on Rat Muscular Mitochondria. Korean J Physiol Pharmacol (2015) 0.75
Training Enhances Immune Cells Mitochondrial Biosynthesis, Fission, Fusion, and Their Antioxidant Capabilities Synergistically with Dietary Docosahexaenoic Supplementation. Oxid Med Cell Longev (2016) 0.75
Role of metabolic stress for enhancing muscle adaptations: Practical applications. World J Methodol (2017) 0.75
Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells. Mol Metab (2017) 0.75
The 12-day thermoregulatory metamorphosis of Red-winged Blackbirds (Agelaius phoeniceus). J Comp Physiol B (2016) 0.75
New insights into the role of mitochondria in aging: mitochondrial dynamics and more. J Cell Sci (2010) 2.03
PPARgamma coactivator-1alpha expression during thyroid hormone- and contractile activity-induced mitochondrial adaptations. Am J Physiol Cell Physiol (2003) 1.88
Mitochondrial function and apoptotic susceptibility in aging skeletal muscle. Aging Cell (2007) 1.71
Interactions between ROS and AMP kinase activity in the regulation of PGC-1alpha transcription in skeletal muscle cells. Am J Physiol Cell Physiol (2008) 1.57
Biogenesis of the mitochondrial Tom40 channel in skeletal muscle from aged animals and its adaptability to chronic contractile activity. Am J Physiol Cell Physiol (2010) 1.53
DJ-1 protects the nigrostriatal axis from the neurotoxin MPTP by modulation of the AKT pathway. Proc Natl Acad Sci U S A (2010) 1.38
AMP-activated protein kinase-regulated activation of the PGC-1alpha promoter in skeletal muscle cells. PLoS One (2008) 1.32
Plasticity of skeletal muscle mitochondria in response to contractile activity. Exp Physiol (2003) 1.25
Regulation of mitochondrial biogenesis in muscle by endurance exercise. Sports Med (2003) 1.24
Negligible direct lactate oxidation in subsarcolemmal and intermyofibrillar mitochondria obtained from red and white rat skeletal muscle. J Physiol (2007) 1.22
Transcriptional and post-transcriptional regulation of mitochondrial biogenesis in skeletal muscle: effects of exercise and aging. Biochim Biophys Acta (2009) 1.17
Differential susceptibility of subsarcolemmal and intermyofibrillar mitochondria to apoptotic stimuli. Am J Physiol Cell Physiol (2005) 1.16
How is mitochondrial biogenesis affected in mitochondrial disease? Med Sci Sports Exerc (2005) 1.09
Expression of mitochondrial fission and fusion regulatory proteins in skeletal muscle during chronic use and disuse. Muscle Nerve (2013) 1.06
Mitochondrial pathways in sarcopenia of aging and disuse muscle atrophy. Biol Chem (2013) 1.04
Expression of key regulators of mitochondrial biogenesis in growth hormone receptor knockout (GHRKO) mice is enhanced but is not further improved by other potential life-extending interventions. J Gerontol A Biol Sci Med Sci (2011) 0.95
Mitochondrial biogenesis and the role of the protein import pathway. Med Sci Sports Exerc (2003) 0.91
Calcium-regulated changes in mitochondrial phenotype in skeletal muscle cells. Am J Physiol Cell Physiol (2004) 0.91
Molecular basis for an attenuated mitochondrial adaptive plasticity in aged skeletal muscle. Aging (Albany NY) (2009) 0.86
Age- and calorie restriction-related changes in rat brain mitochondrial DNA and TFAM binding. Age (Dordr) (2012) 0.85
Effect of chronic contractile activity on SS and IMF mitochondrial apoptotic susceptibility in skeletal muscle. Am J Physiol Endocrinol Metab (2006) 0.84
Safety and Tolerability of Acetazolamide in the Idiopathic Intracranial Hypertension Treatment Trial. J Neuroophthalmol (2016) 0.83
Anaesthetic plus dilating gel improves pupil dilation for cataract surgery. Can J Ophthalmol (2012) 0.83
Aging and calorie restriction oppositely affect mitochondrial biogenesis through TFAM binding at both origins of mitochondrial DNA replication in rat liver. PLoS One (2013) 0.82
Mitochondrial assembly: protein import. Proc Nutr Soc (2004) 0.81
Effect of chronic contractile activity on mRNA stability in skeletal muscle. Am J Physiol Cell Physiol (2010) 0.80
Effect of age on the processing and import of matrix-destined mitochondrial proteins in skeletal muscle. J Gerontol A Biol Sci Med Sci (2010) 0.80
Mechanisms of mitochondrial disease and the role of exercise: a symposium. Med Sci Sports Exerc (2005) 0.75
A method of evaluating helmet rotational acceleration protection using the Kingston Impact Simulator (KIS Unit). Clin J Sport Med (2013) 0.75