Published in Stroke on June 01, 2006
Normobaric hyperoxia reduces the neurovascular complications associated with delayed tissue plasminogen activator treatment in a rat model of focal cerebral ischemia. Stroke (2009) 1.90
The neurovascular unit and combination treatment strategies for stroke. Trends Pharmacol Sci (2012) 1.66
Blood-brain barrier disruption in humans is independently associated with increased matrix metalloproteinase-9. Stroke (2009) 1.56
Matrix metalloproteinase inhibition reduces oxidative stress associated with cerebral amyloid angiopathy in vivo in transgenic mice. J Neurochem (2009) 1.08
Combination therapy of 17beta-estradiol and recombinant tissue plasminogen activator for experimental ischemic stroke. J Pharmacol Exp Ther (2009) 1.02
Plasmin-dependent modulation of the blood-brain barrier: a major consideration during tPA-induced thrombolysis? J Cereb Blood Flow Metab (2014) 0.97
Tissue-type plasminogen activator as a therapeutic target in stroke. Expert Opin Ther Targets (2008) 0.95
Endothelial cells and astrocytes: a concerto en duo in ischemic pathophysiology. Int J Cell Biol (2012) 0.86
Lipid profile, statin use, and outcome after intravenous thrombolysis for acute ischaemic stroke. J Neurol (2008) 0.84
Tissue plasminogen activator enhances the hypoxia/reoxygenation-induced impairment of the blood-brain barrier in a primary culture of rat brain endothelial cells. Cell Mol Neurobiol (2008) 0.84
Molecular mechanisms underlying the effects of statins in the central nervous system. Int J Mol Sci (2014) 0.83
Simvastatin improves clinical scores in a rabbit multiple infarct ischemic stroke model: synergism with a ROCK inhibitor but not the thrombolytic tissue plasminogen activator. Brain Res (2010) 0.81
Effect and Safety of Rosuvastatin in Acute Ischemic Stroke. J Stroke (2016) 0.80
Molecular contributions to neurovascular unit dysfunctions after brain injuries: lessons for target-specific drug development. Future Neurol (2013) 0.79
Hemostasis and alterations of the central nervous system. Semin Thromb Hemost (2013) 0.79
Early statin use in ischemic stroke patients treated with recanalization therapy: retrospective observational study. BMC Neurol (2015) 0.78
Update of the stroke therapy academic industry roundtable preclinical recommendations. Stroke (2009) 6.79
The science of stroke: mechanisms in search of treatments. Neuron (2010) 6.14
Emergence of fatal PRRSV variants: unparalleled outbreaks of atypical PRRS in China and molecular dissection of the unique hallmark. PLoS One (2007) 5.60
Ultrasound-enhanced systemic thrombolysis for acute ischemic stroke. N Engl J Med (2004) 5.32
Role of matrix metalloproteinases in delayed cortical responses after stroke. Nat Med (2006) 5.10
Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies. Lancet Neurol (2012) 3.93
Distinct roles of matrix metalloproteases in the early- and late-phase development of neuropathic pain. Nat Med (2008) 3.83
Plasma microRNA panel to diagnose hepatitis B virus-related hepatocellular carcinoma. J Clin Oncol (2011) 3.80
Lipoprotein receptor-mediated induction of matrix metalloproteinase by tissue plasminogen activator. Nat Med (2003) 3.10
B-type natriuretic peptides and mortality after stroke: a systematic review and meta-analysis. Neurology (2013) 2.98
SSeCKS regulates angiogenesis and tight junction formation in blood-brain barrier. Nat Med (2003) 2.78
European Stroke Organisation (ESO) guidelines for the management of spontaneous intracerebral hemorrhage. Int J Stroke (2014) 2.71
Fibroblast growth factor 21 levels are increased in nonalcoholic fatty liver disease patients and are correlated with hepatic triglyceride. J Hepatol (2010) 2.65
A pilot study of normobaric oxygen therapy in acute ischemic stroke. Stroke (2005) 2.58
Statin therapy and outcome after ischemic stroke: systematic review and meta-analysis of observational studies and randomized trials. Stroke (2013) 2.53
Two-photon high-resolution measurement of partial pressure of oxygen in cerebral vasculature and tissue. Nat Methods (2010) 2.37
New plasmid-mediated quinolone resistance gene, qnrC, found in a clinical isolate of Proteus mirabilis. Antimicrob Agents Chemother (2009) 2.32
Variants at APOE influence risk of deep and lobar intracerebral hemorrhage. Ann Neurol (2010) 2.31
Involvement of matrix metalloproteinase in thrombolysis-associated hemorrhagic transformation after embolic focal ischemia in rats. Stroke (2002) 2.30
Increased brain expression of matrix metalloproteinase-9 after ischemic and hemorrhagic human stroke. Stroke (2006) 2.27
Deficiency of a beta-arrestin-2 signal complex contributes to insulin resistance. Nature (2009) 2.27
Effects of neuroglobin overexpression on acute brain injury and long-term outcomes after focal cerebral ischemia. Stroke (2008) 2.25
Microbubble administration accelerates clot lysis during continuous 2-MHz ultrasound monitoring in stroke patients treated with intravenous tissue plasminogen activator. Stroke (2005) 2.24
Tandem internal carotid artery/middle cerebral artery occlusion: an independent predictor of poor outcome after systemic thrombolysis. Stroke (2006) 2.20
Effects of admission hyperglycemia on stroke outcome in reperfused tissue plasminogen activator--treated patients. Stroke (2003) 2.20
Upper limb ischemic preconditioning prevents recurrent stroke in intracranial arterial stenosis. Neurology (2012) 2.19
Mechanisms of hemorrhagic transformation after tissue plasminogen activator reperfusion therapy for ischemic stroke. Stroke (2004) 2.13
Extension of the thrombolytic time window with minocycline in experimental stroke. Stroke (2008) 2.10
Do you feel my pain? Racial group membership modulates empathic neural responses. J Neurosci (2009) 2.09
Neuroprotection via matrix-trophic coupling between cerebral endothelial cells and neurons. Proc Natl Acad Sci U S A (2008) 2.06
Correlation between brain reorganization, ischemic damage, and neurologic status after transient focal cerebral ischemia in rats: a functional magnetic resonance imaging study. J Neurosci (2003) 2.05
Patterns and predictors of early risk of recurrence after transient ischemic attack with respect to etiologic subtypes. Stroke (2007) 2.03
Cortical spreading depression activates and upregulates MMP-9. J Clin Invest (2004) 1.93
Normobaric hyperoxia improves cerebral blood flow and oxygenation, and inhibits peri-infarct depolarizations in experimental focal ischaemia. Brain (2007) 1.92
Cell-cell signaling in the neurovascular unit. Neurochem Res (2007) 1.92
Higher risk of further vascular events among transient ischemic attack patients with diffusion-weighted imaging acute ischemic lesions. Stroke (2004) 1.91
Stimulus-induced changes in blood flow and 2-deoxyglucose uptake dissociate in ipsilateral somatosensory cortex. J Neurosci (2008) 1.89
Involvement of matrix metalloproteinase in neuroblast cell migration from the subventricular zone after stroke. J Neurosci (2006) 1.85
Meta-analysis in more than 17,900 cases of ischemic stroke reveals a novel association at 12q24.12. Neurology (2014) 1.85
High prevalence of plasmid-mediated quinolone resistance determinants qnr, aac(6')-Ib-cr, and qepA among ceftiofur-resistant Enterobacteriaceae isolates from companion and food-producing animals. Antimicrob Agents Chemother (2008) 1.83
Brain angiogenesis in developmental and pathological processes: neurovascular injury and angiogenic recovery after stroke. FEBS J (2009) 1.82
Serum and urine metabolite profiling reveals potential biomarkers of human hepatocellular carcinoma. Mol Cell Proteomics (2011) 1.81
Temporal profile of matrix metalloproteinases and their inhibitors after spontaneous intracerebral hemorrhage: relationship to clinical and radiological outcome. Stroke (2004) 1.81
Prediction of early neurological deterioration using diffusion- and perfusion-weighted imaging in hyperacute middle cerebral artery ischemic stroke. Stroke (2002) 1.80
The neurotoxicity of tissue plasminogen activator? J Cereb Blood Flow Metab (2004) 1.80
Role for CD47-SIRPalpha signaling in xenograft rejection by macrophages. Proc Natl Acad Sci U S A (2007) 1.80
Multiphasic roles for matrix metalloproteinases after stroke. Curr Opin Pharmacol (2008) 1.79
C-reactive protein predicts further ischemic events in first-ever transient ischemic attack or stroke patients with intracranial large-artery occlusive disease. Stroke (2003) 1.78
Tissue plasminogen activator promotes matrix metalloproteinase-9 upregulation after focal cerebral ischemia. Stroke (2005) 1.77
Impact of admission hyperglycemia on stroke outcome after thrombolysis: risk stratification in relation to time to reperfusion. Stroke (2004) 1.70
Normobaric hyperoxia reduces MRI diffusion abnormalities and infarct size in experimental stroke. Neurology (2002) 1.67
3,4-Methylenedioxymethamphetamine (MDMA) neurotoxicity in rats: a reappraisal of past and present findings. Psychopharmacology (Berl) (2006) 1.66
Developmentally regulated role for Ras-GRFs in coupling NMDA glutamate receptors to Ras, Erk and CREB. EMBO J (2004) 1.65
An oligovascular niche: cerebral endothelial cells promote the survival and proliferation of oligodendrocyte precursor cells. J Neurosci (2009) 1.62
Fingolimod provides long-term protection in rodent models of cerebral ischemia. Ann Neurol (2010) 1.62
Beyond NMDA and AMPA glutamate receptors: emerging mechanisms for ionic imbalance and cell death in stroke. Trends Pharmacol Sci (2008) 1.62
Green tea polyphenol (-)-epigallocatechin gallate reduces neuronal cell damage and up-regulation of MMP-9 activity in hippocampal CA1 and CA2 areas following transient global cerebral ischemia. J Neurosci Res (2009) 1.60
Effects of normobaric hyperoxia in a rat model of focal cerebral ischemia-reperfusion. J Cereb Blood Flow Metab (2002) 1.59
Blood-neural barrier: intercellular communication at glio-vascular interface. J Biochem Mol Biol (2006) 1.59
OCT methods for capillary velocimetry. Biomed Opt Express (2012) 1.57
Role of matrix metalloproteinases in delayed neuronal damage after transient global cerebral ischemia. J Neurosci (2004) 1.56
Astrocytic induction of matrix metalloproteinase-9 and edema in brain hemorrhage. J Cereb Blood Flow Metab (2006) 1.56
Junctional complexes of the blood-brain barrier: permeability changes in neuroinflammation. Prog Neurobiol (2002) 1.55
Fas system activation in perihematomal areas after spontaneous intracerebral hemorrhage. Stroke (2008) 1.52
VEGF-induced BBB permeability is associated with an MMP-9 activity increase in cerebral ischemia: both effects decreased by Ang-1. J Cereb Blood Flow Metab (2005) 1.52
Baicalein and 12/15-lipoxygenase in the ischemic brain. Stroke (2006) 1.50
Experimental model of warfarin-associated intracerebral hemorrhage. Stroke (2008) 1.48
Granulocyte colony-stimulating factor enhances angiogenesis after focal cerebral ischemia. Brain Res (2005) 1.47
Neurovascular proteases in brain injury, hemorrhage and remodeling after stroke. Stroke (2007) 1.47
IL1B and VWF variants are associated with fibrinolytic early recanalization in patients with ischemic stroke. Stroke (2012) 1.45
Annexin A2 combined with low-dose tPA improves thrombolytic therapy in a rat model of focal embolic stroke. J Cereb Blood Flow Metab (2010) 1.44
Hemoglobin-induced cytotoxicity in rat cerebral cortical neurons: caspase activation and oxidative stress. Stroke (2002) 1.43
Normobaric hyperoxia extends the reperfusion window in focal cerebral ischemia. Ann Neurol (2005) 1.42
Extracellular proteolysis in brain injury and inflammation: role for plasminogen activators and matrix metalloproteinases. J Neurosci Res (2002) 1.42