Hermann Schindelin

Author PubWeight™ 60.89‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Crystal structure of the S-adenosylmethionine-dependent enzyme MoaA and its implications for molybdenum cofactor deficiency in humans. Proc Natl Acad Sci U S A 2004 2.51
2 The crystal structure of yeast protein disulfide isomerase suggests cooperativity between its active sites. Cell 2006 2.31
3 Structural insights into E1-catalyzed ubiquitin activation and transfer to conjugating enzymes. Cell 2008 2.28
4 Binding of 5'-GTP to the C-terminal FeS cluster of the radical S-adenosylmethionine enzyme MoaA provides insights into its mechanism. Proc Natl Acad Sci U S A 2006 2.16
5 Candidate amino acids involved in H+ gating of acid-sensing ion channel 1a. J Biol Chem 2007 1.59
6 ENDOR spectroscopy shows that guanine N1 binds to [4Fe-4S] cluster II of the S-adenosylmethionine-dependent enzyme MoaA: mechanistic implications. J Am Chem Soc 2009 1.54
7 The sulfurtransferase activity of Uba4 presents a link between ubiquitin-like protein conjugation and activation of sulfur carrier proteins. Biochemistry 2008 1.44
8 Complex formation between the postsynaptic scaffolding protein gephyrin, profilin, and Mena: a possible link to the microfilament system. J Neurosci 2003 1.40
9 Characterization of MOCS1A, an oxygen-sensitive iron-sulfur protein involved in human molybdenum cofactor biosynthesis. J Biol Chem 2004 1.36
10 The AAA ATPase p97 links peptide N-glycanase to the endoplasmic reticulum-associated E3 ligase autocrine motility factor receptor. Proc Natl Acad Sci U S A 2006 1.26
11 The residence time of GABA(A)Rs at inhibitory synapses is determined by direct binding of the receptor α1 subunit to gephyrin. J Neurosci 2011 1.25
12 Studies on peptide:N-glycanase-p97 interaction suggest that p97 phosphorylation modulates endoplasmic reticulum-associated degradation. Proc Natl Acad Sci U S A 2007 1.21
13 The crystal structure of Cdc42 in complex with collybistin II, a gephyrin-interacting guanine nucleotide exchange factor. J Mol Biol 2006 1.16
14 Hierarchical binding of cofactors to the AAA ATPase p97. Structure 2011 1.14
15 Structural biology of enzymes involved in NAD and molybdenum cofactor biosynthesis. Curr Opin Struct Biol 2002 1.13
16 Structural basis of assembly chaperone- mediated snRNP formation. Mol Cell 2013 1.13
17 The catalytic activity of protein-disulfide isomerase requires a conformationally flexible molecule. J Biol Chem 2008 1.12
18 Deciphering the structural framework of glycine receptor anchoring by gephyrin. EMBO J 2006 1.12
19 Structure of the oligosaccharyl transferase complex at 12 A resolution. Structure 2008 1.10
20 Gephyrin, the enigmatic organizer at GABAergic synapses. Front Cell Neurosci 2012 1.07
21 An Armadillo motif in Ufd3 interacts with Cdc48 and is involved in ubiquitin homeostasis and protein degradation. Proc Natl Acad Sci U S A 2009 1.06
22 Dimeric organization of the yeast oligosaccharyl transferase complex. Proc Natl Acad Sci U S A 2006 1.02
23 Biochemical characterization of the high affinity binding between the glycine receptor and gephyrin. J Biol Chem 2004 1.02
24 Structural and biochemical studies of the C-terminal domain of mouse peptide-N-glycanase identify it as a mannose-binding module. Proc Natl Acad Sci U S A 2006 1.01
25 Structure of the mouse peptide N-glycanase-HR23 complex suggests co-evolution of the endoplasmic reticulum-associated degradation and DNA repair pathways. J Biol Chem 2006 1.01
26 Molecular basis of the γ-aminobutyric acid A receptor α3 subunit interaction with the clustering protein gephyrin. J Biol Chem 2011 1.00
27 Rational design, structural and thermodynamic characterization of a hyperstable variant of the villin headpiece helical subdomain. Biochemistry 2007 0.99
28 The structural and functional basis of the p97/valosin-containing protein (VCP)-interacting motif (VIM): mutually exclusive binding of cofactors to the N-terminal domain of p97. J Biol Chem 2011 0.98
29 Structural studies of molybdopterin synthase provide insights into its catalytic mechanism. J Biol Chem 2003 0.97
30 Differential effects of N-glycans on surface expression suggest structural differences between the acid-sensing ion channel (ASIC) 1a and ASIC1b. Biochem J 2008 0.96
31 The yeast E4 ubiquitin ligase Ufd2 interacts with the ubiquitin-like domains of Rad23 and Dsk2 via a novel and distinct ubiquitin-like binding domain. J Biol Chem 2010 0.95
32 Structural and functional studies suggest a catalytic mechanism for the phosphotransacetylase from Methanosarcina thermophila. J Bacteriol 2006 0.92
33 Specificity of the E1-E2-E3 enzymatic cascade for ubiquitin C-terminal sequences identified by phage display. ACS Chem Biol 2012 0.91
34 Crystal structure of phosphotransacetylase from the methanogenic archaeon Methanosarcina thermophila. Structure 2004 0.91
35 Structural and mutational studies on the importance of oligosaccharide binding for the activity of yeast PNGase. Glycobiology 2008 0.90
36 Gephyrin-mediated γ-aminobutyric acid type A and glycine receptor clustering relies on a common binding site. J Biol Chem 2011 0.90
37 Crystal structure of a molybdopterin synthase-precursor Z complex: insight into its sulfur transfer mechanism and its role in molybdenum cofactor deficiency. Biochemistry 2007 0.89
38 Tyrosine phosphorylation of ATPase p97 regulates its activity during ERAD. Biochem Biophys Res Commun 2008 0.89
39 Site-specific labeling of cytoplasmic peptide:N-glycanase by N,N'-diacetylchitobiose-related compounds. J Biol Chem 2006 0.88
40 Mutational analysis of Escherichia coli MoeA: two functional activities map to the active site cleft. Biochemistry 2007 0.88
41 Multiple modes of interaction of the deglycosylation enzyme, mouse peptide N-glycanase, with the proteasome. Proc Natl Acad Sci U S A 2005 0.86
42 The N-terminus of yeast peptide: N-glycanase interacts with the DNA repair protein Rad23. Biochem Biophys Res Commun 2004 0.86
43 Crystal structure of YnjE from Escherichia coli, a sulfurtransferase with three rhodanese domains. Protein Sci 2009 0.85
44 Orthogonal ubiquitin transfer through engineered E1-E2 cascades for protein ubiquitination. Chem Biol 2012 0.84
45 Structural characterization of gephyrin by AFM and SAXS reveals a mixture of compact and extended states. Acta Crystallogr D Biol Crystallogr 2013 0.82
46 Evolutionary and structural analyses of mammalian haloacid dehalogenase-type phosphatases AUM and chronophin provide insight into the basis of their different substrate specificities. J Biol Chem 2013 0.82
47 Structural insights into functional modes of proteins involved in ubiquitin family pathways. Methods Mol Biol 2012 0.82
48 The crystal structure of the protein-disulfide isomerase family member ERp27 provides insights into its substrate binding capabilities. J Biol Chem 2012 0.80
49 Structural and mechanistic insights into lunatic fringe from a kinetic analysis of enzyme mutants. J Biol Chem 2008 0.80
50 Chronophin dimerization is required for proper positioning of its substrate specificity loop. J Biol Chem 2013 0.79
51 Design and synthesis of high-affinity dimeric inhibitors targeting the interactions between gephyrin and inhibitory neurotransmitter receptors. Angew Chem Int Ed Engl 2014 0.78
52 Phage display to identify Nedd8-mimicking peptides as inhibitors of the Nedd8 transfer cascade. Chembiochem 2013 0.78
53 Inhibiting the protein ubiquitination cascade by ubiquitin-mimicking short peptides. Org Lett 2012 0.78
54 And yet it moves: active site remodeling in the SUMO E1. Structure 2010 0.77
55 Profiling the cross reactivity of ubiquitin with the Nedd8 activating enzyme by phage display. PLoS One 2013 0.76
56 SUMO-mimicking peptides inhibiting protein SUMOylation. Chembiochem 2014 0.75
57 Modulation of gephyrin-glycine receptor affinity by multivalency. ACS Chem Biol 2014 0.75