Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Crystal structure of the S-adenosylmethionine-dependent enzyme MoaA and its implications for molybdenum cofactor deficiency in humans.
|
Proc Natl Acad Sci U S A
|
2004
|
2.51
|
2
|
The crystal structure of yeast protein disulfide isomerase suggests cooperativity between its active sites.
|
Cell
|
2006
|
2.31
|
3
|
Structural insights into E1-catalyzed ubiquitin activation and transfer to conjugating enzymes.
|
Cell
|
2008
|
2.28
|
4
|
Binding of 5'-GTP to the C-terminal FeS cluster of the radical S-adenosylmethionine enzyme MoaA provides insights into its mechanism.
|
Proc Natl Acad Sci U S A
|
2006
|
2.16
|
5
|
Candidate amino acids involved in H+ gating of acid-sensing ion channel 1a.
|
J Biol Chem
|
2007
|
1.59
|
6
|
ENDOR spectroscopy shows that guanine N1 binds to [4Fe-4S] cluster II of the S-adenosylmethionine-dependent enzyme MoaA: mechanistic implications.
|
J Am Chem Soc
|
2009
|
1.54
|
7
|
The sulfurtransferase activity of Uba4 presents a link between ubiquitin-like protein conjugation and activation of sulfur carrier proteins.
|
Biochemistry
|
2008
|
1.44
|
8
|
Complex formation between the postsynaptic scaffolding protein gephyrin, profilin, and Mena: a possible link to the microfilament system.
|
J Neurosci
|
2003
|
1.40
|
9
|
Characterization of MOCS1A, an oxygen-sensitive iron-sulfur protein involved in human molybdenum cofactor biosynthesis.
|
J Biol Chem
|
2004
|
1.36
|
10
|
The AAA ATPase p97 links peptide N-glycanase to the endoplasmic reticulum-associated E3 ligase autocrine motility factor receptor.
|
Proc Natl Acad Sci U S A
|
2006
|
1.26
|
11
|
The residence time of GABA(A)Rs at inhibitory synapses is determined by direct binding of the receptor α1 subunit to gephyrin.
|
J Neurosci
|
2011
|
1.25
|
12
|
Studies on peptide:N-glycanase-p97 interaction suggest that p97 phosphorylation modulates endoplasmic reticulum-associated degradation.
|
Proc Natl Acad Sci U S A
|
2007
|
1.21
|
13
|
The crystal structure of Cdc42 in complex with collybistin II, a gephyrin-interacting guanine nucleotide exchange factor.
|
J Mol Biol
|
2006
|
1.16
|
14
|
Hierarchical binding of cofactors to the AAA ATPase p97.
|
Structure
|
2011
|
1.14
|
15
|
Structural biology of enzymes involved in NAD and molybdenum cofactor biosynthesis.
|
Curr Opin Struct Biol
|
2002
|
1.13
|
16
|
Structural basis of assembly chaperone- mediated snRNP formation.
|
Mol Cell
|
2013
|
1.13
|
17
|
The catalytic activity of protein-disulfide isomerase requires a conformationally flexible molecule.
|
J Biol Chem
|
2008
|
1.12
|
18
|
Deciphering the structural framework of glycine receptor anchoring by gephyrin.
|
EMBO J
|
2006
|
1.12
|
19
|
Structure of the oligosaccharyl transferase complex at 12 A resolution.
|
Structure
|
2008
|
1.10
|
20
|
Gephyrin, the enigmatic organizer at GABAergic synapses.
|
Front Cell Neurosci
|
2012
|
1.07
|
21
|
An Armadillo motif in Ufd3 interacts with Cdc48 and is involved in ubiquitin homeostasis and protein degradation.
|
Proc Natl Acad Sci U S A
|
2009
|
1.06
|
22
|
Dimeric organization of the yeast oligosaccharyl transferase complex.
|
Proc Natl Acad Sci U S A
|
2006
|
1.02
|
23
|
Biochemical characterization of the high affinity binding between the glycine receptor and gephyrin.
|
J Biol Chem
|
2004
|
1.02
|
24
|
Structural and biochemical studies of the C-terminal domain of mouse peptide-N-glycanase identify it as a mannose-binding module.
|
Proc Natl Acad Sci U S A
|
2006
|
1.01
|
25
|
Structure of the mouse peptide N-glycanase-HR23 complex suggests co-evolution of the endoplasmic reticulum-associated degradation and DNA repair pathways.
|
J Biol Chem
|
2006
|
1.01
|
26
|
Molecular basis of the γ-aminobutyric acid A receptor α3 subunit interaction with the clustering protein gephyrin.
|
J Biol Chem
|
2011
|
1.00
|
27
|
Rational design, structural and thermodynamic characterization of a hyperstable variant of the villin headpiece helical subdomain.
|
Biochemistry
|
2007
|
0.99
|
28
|
The structural and functional basis of the p97/valosin-containing protein (VCP)-interacting motif (VIM): mutually exclusive binding of cofactors to the N-terminal domain of p97.
|
J Biol Chem
|
2011
|
0.98
|
29
|
Structural studies of molybdopterin synthase provide insights into its catalytic mechanism.
|
J Biol Chem
|
2003
|
0.97
|
30
|
Differential effects of N-glycans on surface expression suggest structural differences between the acid-sensing ion channel (ASIC) 1a and ASIC1b.
|
Biochem J
|
2008
|
0.96
|
31
|
The yeast E4 ubiquitin ligase Ufd2 interacts with the ubiquitin-like domains of Rad23 and Dsk2 via a novel and distinct ubiquitin-like binding domain.
|
J Biol Chem
|
2010
|
0.95
|
32
|
Structural and functional studies suggest a catalytic mechanism for the phosphotransacetylase from Methanosarcina thermophila.
|
J Bacteriol
|
2006
|
0.92
|
33
|
Specificity of the E1-E2-E3 enzymatic cascade for ubiquitin C-terminal sequences identified by phage display.
|
ACS Chem Biol
|
2012
|
0.91
|
34
|
Crystal structure of phosphotransacetylase from the methanogenic archaeon Methanosarcina thermophila.
|
Structure
|
2004
|
0.91
|
35
|
Structural and mutational studies on the importance of oligosaccharide binding for the activity of yeast PNGase.
|
Glycobiology
|
2008
|
0.90
|
36
|
Gephyrin-mediated γ-aminobutyric acid type A and glycine receptor clustering relies on a common binding site.
|
J Biol Chem
|
2011
|
0.90
|
37
|
Crystal structure of a molybdopterin synthase-precursor Z complex: insight into its sulfur transfer mechanism and its role in molybdenum cofactor deficiency.
|
Biochemistry
|
2007
|
0.89
|
38
|
Tyrosine phosphorylation of ATPase p97 regulates its activity during ERAD.
|
Biochem Biophys Res Commun
|
2008
|
0.89
|
39
|
Site-specific labeling of cytoplasmic peptide:N-glycanase by N,N'-diacetylchitobiose-related compounds.
|
J Biol Chem
|
2006
|
0.88
|
40
|
Mutational analysis of Escherichia coli MoeA: two functional activities map to the active site cleft.
|
Biochemistry
|
2007
|
0.88
|
41
|
Multiple modes of interaction of the deglycosylation enzyme, mouse peptide N-glycanase, with the proteasome.
|
Proc Natl Acad Sci U S A
|
2005
|
0.86
|
42
|
The N-terminus of yeast peptide: N-glycanase interacts with the DNA repair protein Rad23.
|
Biochem Biophys Res Commun
|
2004
|
0.86
|
43
|
Crystal structure of YnjE from Escherichia coli, a sulfurtransferase with three rhodanese domains.
|
Protein Sci
|
2009
|
0.85
|
44
|
Orthogonal ubiquitin transfer through engineered E1-E2 cascades for protein ubiquitination.
|
Chem Biol
|
2012
|
0.84
|
45
|
Structural characterization of gephyrin by AFM and SAXS reveals a mixture of compact and extended states.
|
Acta Crystallogr D Biol Crystallogr
|
2013
|
0.82
|
46
|
Evolutionary and structural analyses of mammalian haloacid dehalogenase-type phosphatases AUM and chronophin provide insight into the basis of their different substrate specificities.
|
J Biol Chem
|
2013
|
0.82
|
47
|
Structural insights into functional modes of proteins involved in ubiquitin family pathways.
|
Methods Mol Biol
|
2012
|
0.82
|
48
|
The crystal structure of the protein-disulfide isomerase family member ERp27 provides insights into its substrate binding capabilities.
|
J Biol Chem
|
2012
|
0.80
|
49
|
Structural and mechanistic insights into lunatic fringe from a kinetic analysis of enzyme mutants.
|
J Biol Chem
|
2008
|
0.80
|
50
|
Chronophin dimerization is required for proper positioning of its substrate specificity loop.
|
J Biol Chem
|
2013
|
0.79
|
51
|
Design and synthesis of high-affinity dimeric inhibitors targeting the interactions between gephyrin and inhibitory neurotransmitter receptors.
|
Angew Chem Int Ed Engl
|
2014
|
0.78
|
52
|
Phage display to identify Nedd8-mimicking peptides as inhibitors of the Nedd8 transfer cascade.
|
Chembiochem
|
2013
|
0.78
|
53
|
Inhibiting the protein ubiquitination cascade by ubiquitin-mimicking short peptides.
|
Org Lett
|
2012
|
0.78
|
54
|
And yet it moves: active site remodeling in the SUMO E1.
|
Structure
|
2010
|
0.77
|
55
|
Profiling the cross reactivity of ubiquitin with the Nedd8 activating enzyme by phage display.
|
PLoS One
|
2013
|
0.76
|
56
|
SUMO-mimicking peptides inhibiting protein SUMOylation.
|
Chembiochem
|
2014
|
0.75
|
57
|
Modulation of gephyrin-glycine receptor affinity by multivalency.
|
ACS Chem Biol
|
2014
|
0.75
|