Published in Mov Disord on September 01, 2006
Creatine Safety and Tolerability in Premanifest HD: PRECREST (PRECREST) | NCT00592995
FreeSurfer. Neuroimage (2012) 8.37
Sustained therapeutic reversal of Huntington's disease by transient repression of huntingtin synthesis. Neuron (2012) 4.48
Cerebral cortex and the clinical expression of Huntington's disease: complexity and heterogeneity. Brain (2008) 2.40
Neurocognitive signs in prodromal Huntington disease. Neuropsychology (2011) 2.14
Striatal and white matter predictors of estimated diagnosis for Huntington disease. Brain Res Bull (2010) 1.79
Extensive early motor and non-motor behavioral deficits are followed by striatal neuronal loss in knock-in Huntington's disease mice. Neuroscience (2008) 1.76
Tapping linked to function and structure in premanifest and symptomatic Huntington disease. Neurology (2010) 1.74
Altered white matter microstructure in the corpus callosum in Huntington's disease: implications for cortical "disconnection". Neuroimage (2009) 1.72
Pathophysiology of Huntington's disease: time-dependent alterations in synaptic and receptor function. Neuroscience (2011) 1.62
Longitudinal change in regional brain volumes in prodromal Huntington disease. J Neurol Neurosurg Psychiatry (2010) 1.53
Automatic detection of preclinical neurodegeneration: presymptomatic Huntington disease. Neurology (2009) 1.22
Magnetic resonance imaging of Huntington's disease: preparing for clinical trials. Neuroscience (2009) 1.14
Mouse models of Huntington's disease and methodological considerations for therapeutic trials. Biochim Biophys Acta (2009) 1.14
Functional compensation of motor function in pre-symptomatic Huntington's disease. Brain (2009) 1.11
Peroxisome-proliferator-activated receptor gamma coactivator 1 α contributes to dysmyelination in experimental models of Huntington's disease. J Neurosci (2011) 1.09
Structural MRI detects progressive regional brain atrophy and neuroprotective effects in N171-82Q Huntington's disease mouse model. Neuroimage (2011) 1.05
Role of cerebral cortex in the neuropathology of Huntington's disease. Front Neural Circuits (2013) 1.02
Contrasting gray and white matter changes in preclinical Huntington disease: an MRI study. Neurology (2010) 1.00
RAN Translation in Huntington Disease. Neuron (2015) 1.00
Assessment of cortical and striatal involvement in 523 Huntington disease brains. Neurology (2012) 1.00
Dopamine imbalance in Huntington's disease: a mechanism for the lack of behavioral flexibility. Front Neurosci (2013) 0.99
Multicenter reliability of diffusion tensor imaging. Brain Connect (2012) 0.97
Loss of corticostriatal and thalamostriatal synaptic terminals precedes striatal projection neuron pathology in heterozygous Q140 Huntington's disease mice. Neurobiol Dis (2013) 0.95
Improvement of neuropathology and transcriptional deficits in CAG 140 knock-in mice supports a beneficial effect of dietary curcumin in Huntington's disease. Mol Neurodegener (2012) 0.93
Neuroimaging biomarkers of neurodegenerative diseases and dementia. Semin Neurol (2013) 0.92
Abnormal motor cortex excitability in preclinical and very early Huntington's disease. Biol Psychiatry (2009) 0.92
Stability effects on results of diffusion tensor imaging analysis by reduction of the number of gradient directions due to motion artifacts: an application to presymptomatic Huntington's disease. PLoS Curr (2011) 0.92
Neuroprotection for Huntington's disease: ready, set, slow. Neurotherapeutics (2008) 0.92
Complexity and heterogeneity: what drives the ever-changing brain in Huntington's disease? Ann N Y Acad Sci (2008) 0.91
Early changes in the hypothalamic region in prodromal Huntington disease revealed by MRI analysis. Neurobiol Dis (2010) 0.91
The Trail Making Test in prodromal Huntington disease: contributions of disease progression to test performance. J Clin Exp Neuropsychol (2011) 0.90
Diffusion Tensor Imaging in Preclinical Huntington's Disease. Brain Imaging Behav (2009) 0.90
Diffusion weighted imaging of prefrontal cortex in prodromal Huntington's disease. Hum Brain Mapp (2013) 0.89
Multi-modal neuroimaging in premanifest and early Huntington's disease: 18 month longitudinal data from the IMAGE-HD study. PLoS One (2013) 0.89
Stability of white matter changes related to Huntington's disease in the presence of imaging noise: a DTI study. PLoS Curr (2011) 0.89
Diffusion-weighted versus volumetric imaging of the striatum in early symptomatic Huntington disease. J Neurol (2009) 0.88
Early white matter abnormalities, progressive brain pathology and motor deficits in a novel knock-in mouse model of Huntington's disease. Hum Mol Genet (2015) 0.87
Reduced functional brain connectivity prior to and after disease onset in Huntington's disease. Neuroimage Clin (2013) 0.87
Striatal atrophy and dendritic alterations in a knock-in mouse model of Huntington's disease. Brain Res Bull (2012) 0.86
CalDAG-GEFI down-regulation in the striatum as a neuroprotective change in Huntington's disease. Hum Mol Genet (2010) 0.86
Altered excitatory and inhibitory inputs to striatal medium-sized spiny neurons and cortical pyramidal neurons in the Q175 mouse model of Huntington's disease. J Neurophysiol (2015) 0.83
Prefrontal cortex white matter tracts in prodromal Huntington disease. Hum Brain Mapp (2015) 0.82
Evaluation of multi-modal, multi-site neuroimaging measures in Huntington's disease: Baseline results from the PADDINGTON study. Neuroimage Clin (2012) 0.82
Evaluating multicenter DTI data in Huntington's disease on site specific effects: An ex post facto approach. Neuroimage Clin (2013) 0.81
Differential loss of thalamostriatal and corticostriatal input to striatal projection neuron types prior to overt motor symptoms in the Q140 knock-in mouse model of Huntington's disease. Front Syst Neurosci (2014) 0.81
Mapping cortico-striatal connectivity onto the cortical surface: a new tractography-based approach to study Huntington disease. PLoS One (2013) 0.81
Oligodendroglia and neurotrophic factors in neurodegeneration. Neurosci Bull (2013) 0.81
Diffusion-prepared fast imaging with steady-state free precession (DP-FISP): a rapid diffusion MRI technique at 7 T. Magn Reson Med (2011) 0.81
Military blast exposure, ageing and white matter integrity. Brain (2015) 0.79
Joint reconstruction of white-matter pathways from longitudinal diffusion MRI data with anatomical priors. Neuroimage (2015) 0.79
Early Detection of Huntington Disease. Future Neurol (2010) 0.79
Clinical severity of Huntington's disease does not always correlate with neuropathologic stage. Mov Disord (2012) 0.79
Besides Huntington's disease, does brain-type creatine kinase play a role in other forms of hearing impairment resulting from a common pathological cause? Aging (Albany NY) (2011) 0.78
Functional Differences Between Direct and Indirect Striatal Output Pathways in Huntington's Disease. J Huntingtons Dis (2012) 0.78
Impact of the control for corrupted diffusion tensor imaging data in comparisons at the group level: an application in Huntington disease. Biomed Eng Online (2014) 0.78
Motor network structure and function are associated with motor performance in Huntington's disease. J Neurol (2016) 0.78
Neuroimaging in Huntington's disease. World J Radiol (2014) 0.78
Altered diffusion tensor imaging measurements in aged transgenic Huntington disease rats. Brain Struct Funct (2012) 0.78
Tau or neurofilament light-Which is the more suitable biomarker for Huntington's disease? PLoS One (2017) 0.77
Magnetization transfer imaging in 'premanifest' Huntington's disease. J Neurol (2009) 0.77
Cholinergic interneurons in the Q140 knockin mouse model of Huntington's disease: Reductions in dendritic branching and thalamostriatal input. J Comp Neurol (2016) 0.77
Cross-sectional and longitudinal multimodal structural imaging in prodromal Huntington's disease. Mov Disord (2016) 0.77
Linking white matter and deep gray matter alterations in premanifest Huntington disease. Neuroimage Clin (2016) 0.77
The evolving role of diffusion magnetic resonance imaging in movement disorders. Curr Neurol Neurosci Rep (2013) 0.77
The thalamic ultrastructural abnormalities in paroxysmal kinesigenic choreoathetosis: a diffusion tensor imaging study. J Neurol (2009) 0.76
Diffusion tensor imaging of spinocerebellar ataxia type 12. Med Sci Monit (2014) 0.76
Oligodendroglia and Myelin in Neurodegenerative Diseases: More Than Just Bystanders? Mol Neurobiol (2015) 0.76
The neuropsychiatry of hyperkinetic movement disorders: insights from neuroimaging into the neural circuit bases of dysfunction. Tremor Other Hyperkinet Mov (N Y) (2013) 0.76
The effects of modafinil on mood and cognition in Huntington's disease. Psychopharmacology (Berl) (2008) 0.76
Structural and molecular myelination deficits occur prior to neuronal loss in the YAC128 and BACHD models of Huntington disease. Hum Mol Genet (2016) 0.76
Test-Retest Reliability of Diffusion Tensor Imaging in Huntington's Disease. PLoS Curr (2014) 0.76
Novel Nut and Bolt Task Quantifies Motor Deficits in Premanifest and Manifest Huntington's Disease. PLoS Curr (2015) 0.75
Multivariate statistical analysis of diffusion imaging parameters using partial least squares: Application to white matter variations in Alzheimer's disease. Neuroimage (2016) 0.75
Major Superficial White Matter Abnormalities in Huntington's Disease. Front Neurosci (2016) 0.75
Correlation between relaxometry and diffusion tensor imaging in the globus pallidus of Huntington's disease patients. PLoS One (2015) 0.75
Spinal cord atrophy in early Huntington's disease. Ann Clin Transl Neurol (2014) 0.75
Monitoring Huntington's disease progression through preclinical and early stages. Neurodegener Dis Manag (2012) 0.75
Longitudinal diffusion changes in prodromal and early HD: Evidence of white-matter tract deterioration. Hum Brain Mapp (2017) 0.75
Progress in Huntington's disease: the search for markers of disease onset and progression. J Neurol (2015) 0.75
Whole brain segmentation: automated labeling of neuroanatomical structures in the human brain. Neuron (2002) 33.99
Automatically parcellating the human cerebral cortex. Cereb Cortex (2004) 18.32
Sequence-independent segmentation of magnetic resonance images. Neuroimage (2004) 11.36
The cortical signature of Alzheimer's disease: regionally specific cortical thinning relates to symptom severity in very mild to mild AD dementia and is detectable in asymptomatic amyloid-positive individuals. Cereb Cortex (2008) 5.36
Medial temporal lobe function and structure in mild cognitive impairment. Ann Neurol (2004) 4.89
Regionally localized thinning of the cerebral cortex in schizophrenia. Arch Gen Psychiatry (2003) 4.84
Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease. Science (2002) 4.72
Imaging of amyloid burden and distribution in cerebral amyloid angiopathy. Ann Neurol (2007) 4.11
Histone deacetylase inhibition by sodium butyrate chemotherapy ameliorates the neurodegenerative phenotype in Huntington's disease mice. J Neurosci (2003) 3.67
Brain morphometry with multiecho MPRAGE. Neuroimage (2008) 3.61
Mindfulness practice leads to increases in regional brain gray matter density. Psychiatry Res (2010) 3.48
Acupuncture de qi, from qualitative history to quantitative measurement. J Altern Complement Med (2007) 3.27
Trastuzumab in the treatment of advanced non-small-cell lung cancer: is there a role? Focus on Eastern Cooperative Oncology Group study 2598. J Clin Oncol (2004) 3.02
Use, costs and comparative effectiveness of robotic assisted, laparoscopic and open urological surgery. J Urol (2012) 2.94
High consistency of regional cortical thinning in aging across multiple samples. Cereb Cortex (2009) 2.88
Hospital volume, utilization, costs and outcomes of robot-assisted laparoscopic radical prostatectomy. J Urol (2012) 2.79
Test-retest and between-site reliability in a multicenter fMRI study. Hum Brain Mapp (2008) 2.63
On-line automatic slice positioning for brain MR imaging. Neuroimage (2005) 2.62
Automated MRI measures identify individuals with mild cognitive impairment and Alzheimer's disease. Brain (2009) 2.61
Choice reaction time performance correlates with diffusion anisotropy in white matter pathways supporting visuospatial attention. Proc Natl Acad Sci U S A (2005) 2.51
Cerebral cortex and the clinical expression of Huntington's disease: complexity and heterogeneity. Brain (2008) 2.40
Influence of surgeon and hospital volume on radical prostatectomy costs. J Urol (2012) 2.37
Activation of the fusiform gyrus when individuals with autism spectrum disorder view faces. Neuroimage (2004) 2.33
Thermal ablation vs surgery for localized kidney cancer: a Surveillance, Epidemiology, and End Results (SEER) database analysis. Urology (2011) 2.24
Automatic segmentation of thalamic nuclei from diffusion tensor magnetic resonance imaging. Neuroimage (2003) 2.12
Stepwise approach for nerve sparing without countertraction during robot-assisted radical prostatectomy: technique and outcomes. Eur Urol (2011) 2.09
Consistent neuroanatomical age-related volume differences across multiple samples. Neurobiol Aging (2009) 2.08
Preoperative electrocardiograms: patient factors predictive of abnormalities. Anesthesiology (2009) 2.05
Caspase cleavage of mutant huntingtin precedes neurodegeneration in Huntington's disease. J Neurosci (2002) 2.05
Detection of entorhinal layer II using 7Tesla [corrected] magnetic resonance imaging. Ann Neurol (2005) 2.02
Therapeutic effects of coenzyme Q10 and remacemide in transgenic mouse models of Huntington's disease. J Neurosci (2002) 2.01
Response monitoring, repetitive behaviour and anterior cingulate abnormalities in autism spectrum disorders (ASD). Brain (2008) 2.00
Chronology of behavioral symptoms and neuropathological sequela in R6/2 Huntington's disease transgenic mice. J Comp Neurol (2005) 1.95
Therapeutic effects of cystamine in a murine model of Huntington's disease. J Neurosci (2002) 1.92
Clinical- and imaging-based prediction of stroke risk after transient ischemic attack: the CIP model. Stroke (2008) 1.88
Comparative analysis of outcomes and costs following open radical cystectomy versus robot-assisted laparoscopic radical cystectomy: results from the US Nationwide Inpatient Sample. Eur Urol (2012) 1.86
A genome scan for modifiers of age at onset in Huntington disease: The HD MAPS study. Am J Hum Genet (2003) 1.85
Suggested objective performance goals and clinical trial design for evaluating catheter-based treatment of critical limb ischemia. J Vasc Surg (2009) 1.81
HIP14, a novel ankyrin domain-containing protein, links huntingtin to intracellular trafficking and endocytosis. Hum Mol Genet (2002) 1.79
Transcriptional modulator H2A histone family, member Y (H2AFY) marks Huntington disease activity in man and mouse. Proc Natl Acad Sci U S A (2011) 1.76
Comparative effectiveness, costs and trends in treatment of small renal masses from 2005 to 2007. BJU Int (2013) 1.73
Altered white matter microstructure in the corpus callosum in Huntington's disease: implications for cortical "disconnection". Neuroimage (2009) 1.72
A functional magnetic resonance imaging study on the neural mechanisms of hyperalgesic nocebo effect. J Neurosci (2008) 1.68
Physicians' needs in coping with emotional stressors: the case for peer support. Arch Surg (2011) 1.66
Selective disruption of the cerebral neocortex in Alzheimer's disease. PLoS One (2010) 1.65
Provision of a soy-based intravenous lipid emulsion at 1 g/kg/d does not prevent cholestasis in neonates. JPEN J Parenter Enteral Nutr (2012) 1.64
Acupuncture mobilizes the brain's default mode and its anti-correlated network in healthy subjects. Brain Res (2009) 1.60
Trends in the care of radical prostatectomy in the United States from 2003 to 2006. BJU Int (2010) 1.57
Age-associated reductions in cerebral blood flow are independent from regional atrophy. Neuroimage (2010) 1.55
PRECREST: a phase II prevention and biomarker trial of creatine in at-risk Huntington disease. Neurology (2014) 1.53
Using the wild bootstrap to quantify uncertainty in diffusion tensor imaging. Hum Brain Mapp (2008) 1.51
Spatial relation between microbleeds and amyloid deposits in amyloid angiopathy. Ann Neurol (2010) 1.50
Histones associated with downregulated genes are hypo-acetylated in Huntington's disease models. Hum Mol Genet (2007) 1.49
Neurovascular coupling, cerebral white matter integrity, and response to cocoa in older people. Neurology (2013) 1.47
Technical refinement and learning curve for attenuating neurapraxia during robotic-assisted radical prostatectomy to improve sexual function. Eur Urol (2012) 1.45
Cognition in healthy aging is related to regional white matter integrity, but not cortical thickness. Neurobiol Aging (2008) 1.45
Expectancy and treatment interactions: a dissociation between acupuncture analgesia and expectancy evoked placebo analgesia. Neuroimage (2008) 1.43
Report of two double-blind randomized placebo-controlled pilot studies of a carbohydrate-rich nutrient mixture for treatment of seasonal affective disorder (SAD). CNS Neurosci Ther (2009) 1.39
Conversion of ischemic brain tissue into infarction increases with age. Stroke (2005) 1.39
Frontal connections and cognitive changes in normal aging rhesus monkeys: a DTI study. Neurobiol Aging (2006) 1.37
Predicting the location of entorhinal cortex from MRI. Neuroimage (2009) 1.35
Cystamine increases L-cysteine levels in Huntington's disease transgenic mouse brain and in a PC12 model of polyglutamine aggregation. J Neurochem (2004) 1.33
An fMRI study on the interaction and dissociation between expectation of pain relief and acupuncture treatment. Neuroimage (2009) 1.32
Anatomical alterations of the visual motion processing network in migraine with and without aura. PLoS Med (2006) 1.32
Boosting the sampling efficiency of q-Ball imaging using multiple wavevector fusion. Magn Reson Med (2007) 1.31
Genome-wide significance for a modifier of age at neurological onset in Huntington's disease at 6q23-24: the HD MAPS study. BMC Med Genet (2006) 1.30
Functional magnetic resonance imaging detection of vascular reactivity in cerebral amyloid angiopathy. Ann Neurol (2012) 1.29
Cancer-related direct-to-consumer advertising: awareness, perceptions, and reported impact among patients undergoing active cancer treatment. J Clin Oncol (2009) 1.28
Statistical group comparison of diffusion tensors via multivariate hypothesis testing. Magn Reson Med (2007) 1.26
Automated MRI measures predict progression to Alzheimer's disease. Neurobiol Aging (2010) 1.25
Thickness of the human cerebral cortex is associated with metrics of cerebrovascular health in a normative sample of community dwelling older adults. Neuroimage (2010) 1.23
Detailed semiautomated MRI based morphometry of the neonatal brain: preliminary results. Neuroimage (2006) 1.22
Magnetic resonance spectroscopy study of oxygen therapy in ischemic stroke. Stroke (2007) 1.22
Sp1 is up-regulated in cellular and transgenic models of Huntington disease, and its reduction is neuroprotective. J Biol Chem (2006) 1.21
Creatine therapy provides neuroprotection after onset of clinical symptoms in Huntington's disease transgenic mice. J Neurochem (2003) 1.20
Multi-site characterization of an fMRI working memory paradigm: reliability of activation indices. Neuroimage (2010) 1.19
The mTOR kinase inhibitor Everolimus decreases S6 kinase phosphorylation but fails to reduce mutant huntingtin levels in brain and is not neuroprotective in the R6/2 mouse model of Huntington's disease. Mol Neurodegener (2010) 1.18
The Sirtuin 2 microtubule deacetylase is an abundant neuronal protein that accumulates in the aging CNS. Hum Mol Genet (2011) 1.17
Validation of the Society for Vascular Surgery's objective performance goals for critical limb ischemia in everyday vascular surgery practice. J Vasc Surg (2011) 1.16
Association between white matter microstructure, executive functions, and processing speed in older adults: the impact of vascular health. Hum Brain Mapp (2011) 1.16
Brain encoding of acupuncture sensation--coupling on-line rating with fMRI. Neuroimage (2009) 1.15
Interexaminer difference in infarct volume measurements on MRI: a source of variance in stroke research. Stroke (2008) 1.14
The neural substrate of arithmetic operations and procedure complexity. Brain Res Cogn Brain Res (2004) 1.14
Interictal alterations of the trigeminal somatosensory pathway and periaqueductal gray matter in migraine. Neuroreport (2007) 1.13
Differing neuropsychological and neuroanatomical correlates of abnormal reading in early-stage semantic dementia and dementia of the Alzheimer type. Neuropsychologia (2004) 1.11
Reduced microstructural integrity of the white matter underlying anterior cingulate cortex is associated with increased saccadic latency in schizophrenia. Neuroimage (2007) 1.10
Patterns of care for radical prostatectomy in the United States from 2003 to 2005. J Urol (2008) 1.08
Neuroprotective effects of synaptic modulation in Huntington's disease R6/2 mice. J Neurosci (2007) 1.07
Reduced density of cholinergic interneurons in the ventral striatum in schizophrenia: an in situ hybridization study. Biol Psychiatry (2005) 1.07
Common SNP-based haplotype analysis of the 4p16.3 Huntington disease gene region. Am J Hum Genet (2012) 1.05
White matter alterations in cerebral amyloid angiopathy measured by diffusion tensor imaging. Stroke (2006) 1.05