Published in Neuroimage on February 12, 2011
Reinstating aberrant mTORC1 activity in Huntington's disease mice improves disease phenotypes. Neuron (2014) 1.51
Choosing an animal model for the study of Huntington's disease. Nat Rev Neurosci (2013) 1.47
Peroxisome-proliferator-activated receptor gamma coactivator 1 α contributes to dysmyelination in experimental models of Huntington's disease. J Neurosci (2011) 1.09
Small-molecule TrkB receptor agonists improve motor function and extend survival in a mouse model of Huntington's disease. Hum Mol Genet (2013) 1.08
Interrogation of brain miRNA and mRNA expression profiles reveals a molecular regulatory network that is perturbed by mutant huntingtin. J Neurochem (2012) 1.05
Quantitative mouse brain phenotyping based on single and multispectral MR protocols. Neuroimage (2012) 0.94
Intrajugular vein delivery of AAV9-RNAi prevents neuropathological changes and weight loss in Huntington's disease mice. Mol Ther (2014) 0.92
Neuroprotective effects of psychotropic drugs in Huntington's disease. Int J Mol Sci (2013) 0.88
Mouse model of intrauterine inflammation: sex-specific differences in long-term neurologic and immune sequelae. Brain Behav Immun (2014) 0.88
Mouse models of polyglutamine diseases in therapeutic approaches: review and data table. Part II. Mol Neurobiol (2012) 0.86
Treatment of depressive-like behaviour in Huntington's disease mice by chronic sertraline and exercise. Br J Pharmacol (2012) 0.85
Mouse models of polyglutamine diseases: review and data table. Part I. Mol Neurobiol (2012) 0.84
Sirtuin 1 activator SRT2104 protects Huntington's disease mice. Ann Clin Transl Neurol (2014) 0.81
Design, manufacture, and analysis of customized phantoms for enhanced quality control in small animal MRI systems. Magn Reson Med (2014) 0.81
Spatiotemporal mapping of brain atrophy in mouse models of Huntington's disease using longitudinal in vivo magnetic resonance imaging. Neuroimage (2012) 0.79
Rhes suppression enhances disease phenotypes in Huntington's disease mice. J Huntingtons Dis (2014) 0.76
Thiol-disulfide Oxidoreductases TRX1 and TMX3 Decrease Neuronal Atrophy in a Lentiviral Mouse Model of Huntington's Disease. PLoS Curr (2015) 0.75
Voxel-based morphometry--the methods. Neuroimage (2000) 34.79
Thresholding of statistical maps in functional neuroimaging using the false discovery rate. Neuroimage (2002) 29.63
Detection of Huntington's disease decades before diagnosis: the Predict-HD study. J Neurol Neurosurg Psychiatry (2007) 5.49
On the metrics and euler-lagrange equations of computational anatomy. Annu Rev Biomed Eng (2002) 4.59
Why voxel-based morphometric analysis should be used with great caution when characterizing group differences. Neuroimage (2004) 4.09
Biological and clinical manifestations of Huntington's disease in the longitudinal TRACK-HD study: cross-sectional analysis of baseline data. Lancet Neurol (2009) 3.82
Onset and rate of striatal atrophy in preclinical Huntington disease. Neurology (2004) 2.81
Diffusion tensor imaging in presymptomatic and early Huntington's disease: Selective white matter pathology and its relationship to clinical measures. Mov Disord (2006) 2.23
Brain structure in preclinical Huntington's disease. Biol Psychiatry (2005) 2.05
Regional specificity of brain atrophy in Huntington's disease. Exp Neurol (1998) 2.02
Therapeutic effects of coenzyme Q10 and remacemide in transgenic mouse models of Huntington's disease. J Neurosci (2002) 2.01
Brain white-matter volume loss and glucose hypometabolism precede the clinical symptoms of Huntington's disease. J Nucl Med (2006) 1.83
Neuroprotective effects of creatine in a transgenic mouse model of Huntington's disease. J Neurosci (2000) 1.79
Striatal and white matter predictors of estimated diagnosis for Huntington disease. Brain Res Bull (2010) 1.79
Voxel-based morphometry in the R6/2 transgenic mouse reveals differences between genotypes not seen with manual 2D morphometry. Neurobiol Dis (2008) 1.73
Altered white matter microstructure in the corpus callosum in Huntington's disease: implications for cortical "disconnection". Neuroimage (2009) 1.72
Rate of caudate atrophy in presymptomatic and symptomatic stages of Huntington's disease. Mov Disord (2000) 1.67
Myelin breakdown and iron changes in Huntington's disease: pathogenesis and treatment implications. Neurochem Res (2007) 1.63
Reduced basal ganglia blood flow and volume in pre-symptomatic, gene-tested persons at-risk for Huntington's disease. Brain (1999) 1.56
Longitudinal change in basal ganglia volume in patients with Huntington's disease. Neurology (1997) 1.56
Quantitative neuropathological changes in presymptomatic Huntington's disease. Ann Neurol (2001) 1.44
Regional white matter change in pre-symptomatic Huntington's disease: a diffusion tensor imaging study. Psychiatry Res (2005) 1.43
Magnetic resonance imaging and micro-computed tomography combined atlas of developing and adult mouse brains for stereotaxic surgery. Neuroscience (2009) 1.39
Striatal volume loss in HD as measured by MRI and the influence of CAG repeat. Neurology (2001) 1.33
Putamen volume reduction on magnetic resonance imaging exceeds caudate changes in mild Huntington's disease. Ann Neurol (1992) 1.31
The antidepressant sertraline improves the phenotype, promotes neurogenesis and increases BDNF levels in the R6/2 Huntington's disease mouse model. Exp Neurol (2007) 1.22
Sertraline slows disease progression and increases neurogenesis in N171-82Q mouse model of Huntington's disease. Neurobiol Dis (2008) 1.22
Cerebral cortex structure in prodromal Huntington disease. Neurobiol Dis (2010) 1.17
Longitudinal characterization of brain atrophy of a Huntington's disease mouse model by automated morphological analyses of magnetic resonance images. Neuroimage (2009) 1.15
Magnetic resonance imaging of Huntington's disease: preparing for clinical trials. Neuroscience (2009) 1.14
Onset and progression of pathologic atrophy in Huntington disease: a longitudinal MR imaging study. AJNR Am J Neuroradiol (2010) 1.13
The progression of regional atrophy in premanifest and early Huntington's disease: a longitudinal voxel-based morphometry study. J Neurol Neurosurg Psychiatry (2009) 1.09
Use of magnetic resonance imaging for anatomical phenotyping of the R6/2 mouse model of Huntington's disease. Neurobiol Dis (2008) 1.06
Analysis of serial magnetic resonance images of mouse brains using image registration. Neuroimage (2008) 1.02
Global cerebral atrophy in early stages of Huntington's disease: quantitative MRI study. Neuroreport (2004) 0.96
Single photon emission computed tomographic blood flow and magnetic resonance volume imaging of basal ganglia in Huntington's disease. Arch Neurol (1996) 0.89
Rate and acceleration of whole-brain atrophy in premanifest and early Huntington's disease. Mov Disord (2010) 0.79
Fiber tract-based atlas of human white matter anatomy. Radiology (2003) 10.18
DtiStudio: resource program for diffusion tensor computation and fiber bundle tracking. Comput Methods Programs Biomed (2006) 7.65
Reproducibility of quantitative tractography methods applied to cerebral white matter. Neuroimage (2007) 7.14
Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity. Proc Natl Acad Sci U S A (2005) 6.98
Stereotaxic white matter atlas based on diffusion tensor imaging in an ICBM template. Neuroimage (2008) 6.58
Principles of diffusion tensor imaging and its applications to basic neuroscience research. Neuron (2006) 6.51
Kinase activity of mutant LRRK2 mediates neuronal toxicity. Nat Neurosci (2006) 5.32
Tract probability maps in stereotaxic spaces: analyses of white matter anatomy and tract-specific quantification. Neuroimage (2007) 5.23
Parkin mediates nonclassical, proteasomal-independent ubiquitination of synphilin-1: implications for Lewy body formation. J Neurosci (2005) 3.92
A schizophrenia-associated mutation of DISC1 perturbs cerebral cortex development. Nat Cell Biol (2005) 3.89
Atlas-based whole brain white matter analysis using large deformation diffeomorphic metric mapping: application to normal elderly and Alzheimer's disease participants. Neuroimage (2009) 3.74
Preparing for preventive clinical trials: the Predict-HD study. Arch Neurol (2006) 3.57
NOTCH pathway blockade depletes CD133-positive glioblastoma cells and inhibits growth of tumor neurospheres and xenografts. Stem Cells (2010) 3.42
Disrupted-in-Schizophrenia-1 (DISC-1): mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowth. Proc Natl Acad Sci U S A (2002) 3.34
Multi-parametric neuroimaging reproducibility: a 3-T resource study. Neuroimage (2010) 3.32
Evidence that brain-derived neurotrophic factor is required for basal neurogenesis and mediates, in part, the enhancement of neurogenesis by dietary restriction in the hippocampus of adult mice. J Neurochem (2002) 3.27
p53 mediates cellular dysfunction and behavioral abnormalities in Huntington's disease. Neuron (2005) 3.13
Pediatric diffusion tensor imaging: normal database and observation of the white matter maturation in early childhood. Neuroimage (2005) 3.11
Dominant-negative DISC1 transgenic mice display schizophrenia-associated phenotypes detected by measures translatable to humans. Proc Natl Acad Sci U S A (2007) 3.02
Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degeneration. Proc Natl Acad Sci U S A (2005) 3.00
Effects of diffusion weighting schemes on the reproducibility of DTI-derived fractional anisotropy, mean diffusivity, and principal eigenvector measurements at 1.5T. Neuroimage (2007) 2.92
Human brain white matter atlas: identification and assignment of common anatomical structures in superficial white matter. Neuroimage (2008) 2.86
Diffusion tensor imaging and beyond. Magn Reson Med (2011) 2.78
Spatial normalization of diffusion tensor fields. Magn Reson Med (2003) 2.70
White and gray matter development in human fetal, newborn and pediatric brains. Neuroimage (2006) 2.55
Psychopathology in patients with degenerative cerebellar diseases: a comparison to Huntington's disease. Am J Psychiatry (2002) 2.52
Filopodia are required for cortical neurite initiation. Nat Cell Biol (2007) 2.49
Effects of signal-to-noise ratio on the accuracy and reproducibility of diffusion tensor imaging-derived fractional anisotropy, mean diffusivity, and principal eigenvector measurements at 1.5 T. J Magn Reson Imaging (2007) 2.44
Multi-contrast human neonatal brain atlas: application to normal neonate development analysis. Neuroimage (2011) 2.41
Towards multimodal atlases of the human brain. Nat Rev Neurosci (2006) 2.37
Electric field and stimulating influence generated by deep brain stimulation of the subthalamic nucleus. Clin Neurophysiol (2004) 2.37
Analysis of noise effects on DTI-based tractography using the brute-force and multi-ROI approach. Magn Reson Med (2004) 2.35
Sensory and motor deficits in children with cerebral palsy born preterm correlate with diffusion tensor imaging abnormalities in thalamocortical pathways. Dev Med Child Neurol (2009) 2.34
Towards effective and rewarding data sharing. Neuroinformatics (2003) 2.24
Diffusion tensor imaging in children and adolescents: reproducibility, hemispheric, and age-related differences. Neuroimage (2006) 2.21
Atlas-guided tract reconstruction for automated and comprehensive examination of the white matter anatomy. Neuroimage (2010) 2.21
Beyond disgust: impaired recognition of negative emotions prior to diagnosis in Huntington's disease. Brain (2007) 2.17
Mechanism of magnetization transfer during on-resonance water saturation. A new approach to detect mobile proteins, peptides, and lipids. Magn Reson Med (2003) 2.14
DTI tractography based parcellation of white matter: application to the mid-sagittal morphology of corpus callosum. Neuroimage (2005) 2.13
Huntingtin spheroids and protofibrils as precursors in polyglutamine fibrilization. J Biol Chem (2002) 2.12
A Drosophila model for LRRK2-linked parkinsonism. Proc Natl Acad Sci U S A (2008) 2.12
Prenatal interaction of mutant DISC1 and immune activation produces adult psychopathology. Biol Psychiatry (2010) 2.11
High resolution diffusion tensor imaging of axonal damage in focal inflammatory and demyelinating lesions in rat spinal cord. Brain (2007) 2.03
Acute kidney injury leads to inflammation and functional changes in the brain. J Am Soc Nephrol (2008) 2.03
Multi-contrast large deformation diffeomorphic metric mapping for diffusion tensor imaging. Neuroimage (2009) 2.01
Ena/VASP Is Required for neuritogenesis in the developing cortex. Neuron (2007) 2.01
An MRI-based atlas and database of the developing mouse brain. Neuroimage (2010) 1.99
Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets. Nat Med (2011) 1.97
Endoplasmic reticulum stress and mitochondrial cell death pathways mediate A53T mutant alpha-synuclein-induced toxicity. Hum Mol Genet (2005) 1.92
Fiber density index correlates with reduced fractional anisotropy in white matter of patients with glioblastoma. AJNR Am J Neuroradiol (2005) 1.90
Atlas-based analysis of neurodevelopment from infancy to adulthood using diffusion tensor imaging and applications for automated abnormality detection. Neuroimage (2010) 1.89
A framework for callosal fiber distribution analysis. Neuroimage (2002) 1.87
Diffusion-tensor MR imaging and fiber tractography: a new method of describing aberrant fiber connections in developmental CNS anomalies. Radiographics (2005) 1.86
A genome scan for modifiers of age at onset in Huntington disease: The HD MAPS study. Am J Hum Genet (2003) 1.85
Robo1 regulates the development of major axon tracts and interneuron migration in the forebrain. Development (2006) 1.83
Three-dimensional anatomical characterization of the developing mouse brain by diffusion tensor microimaging. Neuroimage (2003) 1.80
Diffusion tensor magnetic resonance imaging of Wallerian degeneration in rat spinal cord after dorsal root axotomy. J Neurosci (2009) 1.79
Striatal and white matter predictors of estimated diagnosis for Huntington disease. Brain Res Bull (2010) 1.79
Modification of brain aging and neurodegenerative disorders by genes, diet, and behavior. Physiol Rev (2002) 1.77
"Frontal" behaviors before the diagnosis of Huntington's disease and their relationship to markers of disease progression: evidence of early lack of awareness. J Neuropsychiatry Clin Neurosci (2010) 1.76
Alpha-synuclein phosphorylation enhances eosinophilic cytoplasmic inclusion formation in SH-SY5Y cells. J Neurosci (2005) 1.75
Motor abnormalities in premanifest persons with Huntington's disease: the PREDICT-HD study. Mov Disord (2009) 1.73
Anatomical characterization of human fetal brain development with diffusion tensor magnetic resonance imaging. J Neurosci (2009) 1.66
Axonal growth and guidance defects in Frizzled3 knock-out mice: a comparison of diffusion tensor magnetic resonance imaging, neurofilament staining, and genetically directed cell labeling. J Neurosci (2006) 1.64
CHIP regulates leucine-rich repeat kinase-2 ubiquitination, degradation, and toxicity. Proc Natl Acad Sci U S A (2009) 1.64
Multiparametric magnetic resonance imaging analysis of the corticospinal tract in multiple sclerosis. Neuroimage (2007) 1.62
Polyglutamine expansion of huntingtin impairs its nuclear export. Nat Genet (2005) 1.62
Huntington's disease--like 2 is associated with CUG repeat-containing RNA foci. Ann Neurol (2007) 1.61
Single particle characterization of iron-induced pore-forming alpha-synuclein oligomers. J Biol Chem (2008) 1.56
Verbal episodic memory declines prior to diagnosis in Huntington's disease. Neuropsychologia (2007) 1.54
Mapping postnatal mouse brain development with diffusion tensor microimaging. Neuroimage (2005) 1.53
Longitudinal change in regional brain volumes in prodromal Huntington disease. J Neurol Neurosurg Psychiatry (2010) 1.53
Correction of B0 susceptibility induced distortion in diffusion-weighted images using large-deformation diffeomorphic metric mapping. Magn Reson Imaging (2008) 1.48
Diffusion tensor imaging to assess axonal regeneration in peripheral nerves. Exp Neurol (2009) 1.48
Mutant huntingtin N-terminal fragments of specific size mediate aggregation and toxicity in neuronal cells. J Biol Chem (2009) 1.47