Suppression of the interferon-mediated innate immune response by pseudorabies virus.

PubWeight™: 1.01‹?› | Rank: Top 15%

🔗 View Article (PMC 1488972)

Published in J Virol on July 01, 2006

Authors

Alla Brukman1, L W Enquist

Author Affiliations

1: Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA.

Articles citing this

Gene expression patterns in blood leukocytes discriminate patients with acute infections. Blood (2006) 5.05

Comparison of the biological and biochemical activities of several members of the alphaherpesvirus ICP0 family of proteins. J Virol (2010) 1.32

Whole-genome analysis of pseudorabies virus gene expression by real-time quantitative RT-PCR assay. BMC Genomics (2009) 1.07

Transcriptomic analysis of the dialogue between Pseudorabies virus and porcine epithelial cells during infection. BMC Genomics (2008) 1.05

A common neuronal response to alphaherpesvirus infection. J Neuroimmune Pharmacol (2010) 1.02

M135R is a novel cell surface virulence factor of myxoma virus. J Virol (2006) 0.94

Pseudorabies virus EP0 protein counteracts an interferon-induced antiviral state in a species-specific manner. J Virol (2006) 0.85

HSV-2 inhibits type-I interferon signaling via multiple complementary and compensatory STAT2-associated mechanisms. Virus Res (2012) 0.83

A limited innate immune response is induced by a replication-defective herpes simplex virus vector following delivery to the murine central nervous system. J Neurovirol (2009) 0.81

Cytokine protein expression levels in tracheobronchial lymph node homogenates of pigs infected with pseudorabies virus. Clin Vaccine Immunol (2010) 0.79

Extremes of Interferon-Stimulated Gene Expression Associate with Worse Outcomes in the Acute Respiratory Distress Syndrome. PLoS One (2016) 0.75

Pseudorabies Virus dUTPase UL50 Induces Lysosomal Degradation of Type I Interferon Receptor 1 and Antagonizes the Alpha Interferon Response. J Virol (2017) 0.75

Articles cited by this

Antiviral actions of interferons. Clin Microbiol Rev (2001) 13.06

Viruses and interferon: a fight for supremacy. Nat Rev Immunol (2002) 7.92

Viruses and interferons. Annu Rev Microbiol (2001) 7.12

The gamma(1)34.5 protein of herpes simplex virus 1 complexes with protein phosphatase 1alpha to dephosphorylate the alpha subunit of the eukaryotic translation initiation factor 2 and preclude the shutoff of protein synthesis by double-stranded RNA-activated protein kinase. Proc Natl Acad Sci U S A (1997) 6.08

Characterization of the envelope proteins of pseudorabies virus. J Virol (1984) 3.57

The virus battles: IFN induction of the antiviral state and mechanisms of viral evasion. Cytokine Growth Factor Rev (2001) 3.34

Molecular biology of pseudorabies virus: impact on neurovirology and veterinary medicine. Microbiol Mol Biol Rev (2005) 3.06

Aujeszky's disease (pseudorabies) virus: the virus and molecular pathogenesis--state of the art, June 1999. Vet Res (2000) 2.94

Herpes simplex virus triggers and then disarms a host antiviral response. J Virol (2001) 2.82

Expression of herpes simplex virus ICP0 inhibits the induction of interferon-stimulated genes by viral infection. J Virol (2002) 2.38

The herpes simplex virus ICP0 RING finger domain inhibits IRF3- and IRF7-mediated activation of interferon-stimulated genes. J Virol (2004) 2.32

Alphaherpesvirus proteins related to herpes simplex virus type 1 ICP0 affect cellular structures and proteins. J Virol (2000) 2.25

Requirement for IRF-1 in the microenvironment supporting development of natural killer cells. Nature (1998) 2.17

The herpes simplex virus US11 protein effectively compensates for the gamma1(34.5) gene if present before activation of protein kinase R by precluding its phosphorylation and that of the alpha subunit of eukaryotic translation initiation factor 2. J Virol (1998) 2.13

Molecular phylogeny of the alphaherpesvirinae subfamily and a proposed evolutionary timescale. J Mol Biol (1994) 2.09

Stats: multifaceted regulators of transcription. J Interferon Cytokine Res (2005) 2.02

Antibody-dependent enhancement of viral infection: molecular mechanisms and in vivo implications. Rev Med Virol (2003) 1.88

Inhibition of PKR activation by the proline-rich RNA binding domain of the herpes simplex virus type 1 Us11 protein. J Virol (2000) 1.78

Ringing the interferon alarm: differential regulation of gene expression at the interface between innate and adaptive immunity. Curr Opin Immunol (2003) 1.78

Differentiation of vaccine strains and field isolates of pseudorabies (Aujeszky's disease) virus: thermal sensitivity and rabbit virulence markers. Arch Virol (1979) 1.58

Infection of neonatal mice with sindbis virus results in a systemic inflammatory response syndrome. J Virol (1999) 1.56

Two modes of pseudorabies virus neuroinvasion and lethality in mice. J Virol (2004) 1.51

Interference with antigen processing by viruses. Curr Opin Immunol (1997) 1.40

TLR3-mediated signal induces proinflammatory cytokine and chemokine gene expression in astrocytes: differential signaling mechanisms of TLR3-induced IP-10 and IL-8 gene expression. Glia (2006) 1.38

Induction of suppressor of cytokine signaling-3 by herpes simplex virus type 1 contributes to inhibition of the interferon signaling pathway. J Virol (2004) 1.36

Herpes simplex virus 1 gene products occlude the interferon signaling pathway at multiple sites. J Virol (2004) 1.34

Herpes simplex virus type 1 suppresses the interferon signaling pathway by inhibiting phosphorylation of STATs and janus kinases during an early infection stage. Virology (2001) 1.34

Studies on immunisation of pigs with the Bartha strain of Aujeszky's disease virus. Res Vet Sci (1975) 1.32

Transcriptional response of a common permissive cell type to infection by two diverse alphaherpesviruses. J Virol (2004) 1.31

Herpesviruses and the innate immune response. Viral Immunol (2005) 1.27

cC1q-R (calreticulin) and gC1q-R/p33: ubiquitously expressed multi-ligand binding cellular proteins involved in inflammation and infection. Mol Immunol (2004) 1.25

Interplay between alpha/beta and gamma interferons with B, T, and natural killer cells in the defense against herpes simplex virus type 1. J Virol (2004) 1.24

Alternative and accessory pathways in the regulation of IFN-beta-mediated gene expression. J Interferon Cytokine Res (2005) 1.11

Differential effect of murine alpha/beta interferon transgenes on antagonization of herpes simplex virus type 1 replication. J Virol (2002) 1.10

Pseudorabies virus glycoprotein gI: in vitro and in vivo analysis of immunorelevant epitopes. J Gen Virol (1990) 1.10

A role for IFN-alpha beta in virus infection-induced sensitization to endotoxin. J Immunol (2001) 1.09

The comparative anti-herpes simplex virus effects of human interferons. J Interferon Cytokine Res (1998) 0.98

The antiviral cytomegalovirus inducible gene 5/viperin is expressed in atherosclerosis and regulated by proinflammatory agents. Arterioscler Thromb Vasc Biol (2005) 0.95

Pseudorabies virus (PRV) early protein 0 activates PRV gene transcription in combination with the immediate-early protein IE180 and enhances the infectivity of PRV genomic DNA. Vet Microbiol (1998) 0.87

Transcriptome signature of virulent and attenuated pseudorabies virus-infected rodent brain. J Virol (2006) 0.87

Articles by these authors

(truncated to the top 100)

Nucleotide sequences of integrated Moloney sarcoma provirus long terminal repeats and their host and viral junctions. Proc Natl Acad Sci U S A (1980) 7.77

Cloning specific segments of the mammalian genome: bacteriophage lambda containing mouse globin and surrounding gene sequences. Proc Natl Acad Sci U S A (1977) 5.28

Construction and characterization of a recombinant plasmid encoding the gene for the thymidine kinase of Herpes simplex type 1 virus. Gene (1979) 5.09

Herpes simplex virus type-1 glycoprotein D gene: nucleotide sequence and expression in Escherichia coli. Science (1982) 4.28

Construction and transposon mutagenesis in Escherichia coli of a full-length infectious clone of pseudorabies virus, an alphaherpesvirus. J Virol (1999) 4.19

Replication of bacteriophage lambda DNA dependent on the function of host and viral genes. I. Interaction of red, gam and rec. J Mol Biol (1973) 4.04

Effect of brefeldin A on alphaherpesvirus membrane protein glycosylation and virus egress. J Virol (1991) 3.58

Cloning of herpes simplex type 1 DNA fragments in a bacteriophage lambda vector. Science (1979) 3.47

A self-recombining bacterial artificial chromosome and its application for analysis of herpesvirus pathogenesis. Proc Natl Acad Sci U S A (2000) 3.45

Herpesviruses use bidirectional fast-axonal transport to spread in sensory neurons. Proc Natl Acad Sci U S A (2001) 3.34

Neurotropic properties of pseudorabies virus: uptake and transneuronal passage in the rat central nervous system. J Neurosci (1990) 3.01

Cloning of integrated Moloney sarcoma proviral DNA sequences in bacteriophage lambda. Proc Natl Acad Sci U S A (1979) 2.98

Specific pseudorabies virus infection of the rat visual system requires both gI and gp63 glycoproteins. J Virol (1993) 2.92

Characterization of a pseudorabies virus glycoprotein gene with homology to herpes simplex virus type 1 and type 2 glycoprotein C. J Virol (1986) 2.79

Olfactory inputs to hypothalamic neurons controlling reproduction and fertility. Cell (2005) 2.73

Pseudorabies virus envelope glycoprotein gI influences both neurotropism and virulence during infection of the rat visual system. J Virol (1992) 2.69

Pseudorabies virus infection of the rat central nervous system: ultrastructural characterization of viral replication, transport, and pathogenesis. J Neurosci (1993) 2.64

Pseudorabies virus gene encoding glycoprotein gIII is not essential for growth in tissue culture. J Virol (1986) 2.47

Two alpha-herpesvirus strains are transported differentially in the rodent visual system. Neuron (1991) 2.46

Role of envelope protein gE endocytosis in the pseudorabies virus life cycle. J Virol (1998) 2.32

A genetic analysis of the att-int-xis region of coliphage lambda. J Mol Biol (1977) 2.29

Role for DNA homology in site-specific recombination. The isolation and characterization of a site affinity mutant of coliphage lambda. J Mol Biol (1983) 2.20

Pseudorabies virus expressing enhanced green fluorescent protein: A tool for in vitro electrophysiological analysis of transsynaptically labeled neurons in identified central nervous system circuits. Proc Natl Acad Sci U S A (2000) 2.18

Role of the cytoplasmic tail of pseudorabies virus glycoprotein E in virion formation. J Virol (2000) 2.17

Local modulation of plus-end transport targets herpesvirus entry and egress in sensory axons. Proc Natl Acad Sci U S A (2004) 2.17

Mutation of the YXXL endocytosis motif in the cytoplasmic tail of pseudorabies virus gE. J Virol (1999) 2.13

A conserved alpha-herpesvirus protein necessary for axonal localization of viral membrane proteins. J Cell Biol (2001) 2.09

Neuron-to-cell spread of pseudorabies virus in a compartmented neuronal culture system. J Virol (2005) 2.05

Role of pseudorabies virus Us9, a type II membrane protein, in infection of tissue culture cells and the rat nervous system. J Virol (2000) 1.97

Heterogeneity of a fluorescent tegument component in single pseudorabies virus virions and enveloped axonal assemblies. J Virol (2005) 1.92

The red plaque test: a rapid method for identification of excision defective variants of bacteriophage lambda. Virology (1976) 1.87

Pseudorabies virus glycoprotein gIII is required for efficient virus growth in tissue culture. J Virol (1988) 1.85

Transfection of Escherichia coli spheroplasts. V. Activity of recBC nuclease in rec+ and rec minus spheroplasts measured with different forms of bacteriophage DNA. J Virol (1975) 1.85

The Us9 gene product of pseudorabies virus, an alphaherpesvirus, is a phosphorylated, tail-anchored type II membrane protein. J Virol (1998) 1.84

Analysis of pseudorabies virus glycoprotein gIII localization and modification by using novel infectious viral mutants carrying unique EcoRI sites. J Virol (1987) 1.80

Characterization of pseudorabies virus mutants expressing carboxy-terminal truncations of gE: evidence for envelope incorporation, virulence, and neurotropism domains. J Virol (1997) 1.79

Sorting and transport of alpha herpesviruses in axons. Traffic (2001) 1.76

Innervation of the heart and its central medullary origin defined by viral tracing. Science (1994) 1.71

Sequence variability in clinical and laboratory isolates of herpes simplex virus 1 reveals new mutations. J Virol (2010) 1.71

A wide extent of inter-strain diversity in virulent and vaccine strains of alphaherpesviruses. PLoS Pathog (2011) 1.63

Making the case: married versus separate models of alphaherpes virus anterograde transport in axons. Rev Med Virol (2012) 1.63

Two modes of pseudorabies virus neuroinvasion and lethality in mice. J Virol (2004) 1.51

The export pathway of the pseudorabies virus gB homolog gII involves oligomer formation in the endoplasmic reticulum and protease processing in the Golgi apparatus. J Virol (1990) 1.49

A chicken embryo eye model for the analysis of alphaherpesvirus neuronal spread and virulence. J Virol (1998) 1.48

Pseudorabies virus Us9 directs axonal sorting of viral capsids. J Virol (2007) 1.48

Definition of neuronal circuitry controlling the activity of phrenic and abdominal motoneurons in the ferret using recombinant strains of pseudorabies virus. J Neurosci (2000) 1.47

Influence of infectious dose upon productive replication and transynaptic passage of pseudorabies virus in rat central nervous system. J Neurovirol (1995) 1.47

Intracellular trafficking and localization of the pseudorabies virus Us9 type II envelope protein to host and viral membranes. J Virol (1999) 1.47

The pseudorabies virus VP22 homologue (UL49) is dispensable for virus growth in vitro and has no effect on virulence and neuronal spread in rodents. J Virol (2002) 1.45

The gene encoding the gIII envelope protein of pseudorabies virus vaccine strain Bartha contains a mutation affecting protein localization. J Virol (1989) 1.44

Directional transneuronal infection by pseudorabies virus is dependent on an acidic internalization motif in the Us9 cytoplasmic tail. J Virol (2000) 1.42

Reiterated sequences within the intron of an immediate-early gene of herpes simplex virus type 1. Nucleic Acids Res (1981) 1.42

Construction of E. coli expression plasmid libraries: localization of a pseudorabies virus glycoprotein gene. J Mol Appl Genet (1984) 1.41

An immunologically active chimaeric protein containing herpes simplex virus type 1 glycoprotein D. Nature (1983) 1.40

Strand exchange in site-specific recombination. Proc Natl Acad Sci U S A (1979) 1.39

Spatiotemporal responses of astrocytes, ramified microglia, and brain macrophages to central neuronal infection with pseudorabies virus. J Neurosci (1993) 1.37

Pseudorabies virus membrane proteins gI and gE facilitate anterograde spread of infection in projection-specific neurons in the rat. J Virol (2000) 1.37

Strand exchange in lambda integrative recombination: genetics, biochemistry, and models. Cold Spring Harb Symp Quant Biol (1981) 1.36

Characterization of coliphage lambda hybrids carrying DNA fragments from Herpes simplex virus type 1 defective interfering particles. Gene (1981) 1.36

Efficient axonal localization of alphaherpesvirus structural proteins in cultured sympathetic neurons requires viral glycoprotein E. J Virol (2005) 1.36

In vitro analysis of transneuronal spread of an alphaherpesvirus infection in peripheral nervous system neurons. J Virol (2007) 1.35

The alpha-herpesviruses: molecular pathfinders in nervous system circuits. Trends Mol Med (2008) 1.31

A microfluidic chamber for analysis of neuron-to-cell spread and axonal transport of an alpha-herpesvirus. PLoS One (2008) 1.31

Transcriptional response of a common permissive cell type to infection by two diverse alphaherpesviruses. J Virol (2004) 1.31

Role of the pseudorabies virus gI cytoplasmic domain in neuroinvasion, virulence, and posttranslational N-linked glycosylation. J Virol (2000) 1.31

Proteomic characterization of pseudorabies virus extracellular virions. J Virol (2011) 1.30

Retrograde, transneuronal spread of pseudorabies virus in defined neuronal circuitry of the rat brain is facilitated by gE mutations that reduce virulence. J Virol (1999) 1.29

Dendritic morphology of cardiac related medullary neurons defined by circuit-specific infection by a recombinant pseudorabies virus expressing beta-galactosidase. J Neurovirol (1995) 1.28

Pseudorabies virus recombinants expressing functional virulence determinants gE and gI from bovine herpesvirus 1.1. J Virol (1997) 1.27

Insertions in the gG gene of pseudorabies virus reduce expression of the upstream Us3 protein and inhibit cell-to-cell spread of virus infection. J Virol (2001) 1.27

Neurovirulence of pseudorabies virus. Crit Rev Neurobiol (1995) 1.26

Construction of an infectious pseudorabies virus recombinant expressing a glycoprotein gIII-beta-galactosidase fusion protein. Gene (1986) 1.26

The cloning of mouse globin and surrounding gene sequences in bacteriophage lambda. Cold Spring Harb Symp Quant Biol (1978) 1.24

Characterization of integrated Moloney Sarcoma proviruses and flanking host sequences cloned in bacteriophage lambda. Cold Spring Harb Symp Quant Biol (1980) 1.24

Bacterial synthesis of herpes simplex virus types 1 and 2 glycoprotein D antigens. J Invest Dermatol (1984) 1.23

Different patterns of neuronal infection after intracerebral injection of two strains of pseudorabies virus. J Virol (1998) 1.20

The role of virion membrane protein endocytosis in the herpesvirus life cycle. J Clin Virol (2000) 1.17

The gIII glycoprotein of pseudorabies virus is involved in two distinct steps of virus attachment. J Virol (1991) 1.17

Circuit-specific coinfection of neurons in the rat central nervous system with two pseudorabies virus recombinants. J Virol (1999) 1.16

Characterization of the herpes simplex virus type 1 glycoprotein D mRNA and expression of this protein in Xenopus oocytes. Nucleic Acids Res (1983) 1.16

Central neuronal circuit innervating the rat heart defined by transneuronal transport of pseudorabies virus. J Neurosci (1995) 1.15

Characterization of the multisynaptic neuronal control of the rat pineal gland using viral transneuronal tracing. Eur J Neurosci (1998) 1.15

Interconnected parallel circuits between rat nucleus accumbens and thalamus revealed by retrograde transynaptic transport of pseudorabies virus. J Neurosci (1997) 1.14

Neuroinvasiveness of pseudorabies virus injected intracerebrally is dependent on viral concentration and terminal field density. J Comp Neurol (1999) 1.14

Actin and Rho GTPases in herpesvirus biology. Trends Microbiol (2007) 1.13

Visualization of an alphaherpesvirus membrane protein that is essential for anterograde axonal spread of infection in neurons. MBio (2012) 1.12

Glycoprotein D-independent spread of pseudorabies virus infection in cultured peripheral nervous system neurons in a compartmented system. J Virol (2007) 1.11

The secondary attachment site for bacteriophage lambda in the proA/B gene of Escherichia coli. J Mol Biol (1980) 1.11

Synthesis, processing, and oligomerization of bovine herpesvirus 1 gE and gI membrane proteins. J Virol (1996) 1.10

Isolation and characterization of a cloned DNA sequence associated with the murine Ah locus and a 3-methylcholanthrene-induced form of cytochrome P-450. Proc Natl Acad Sci U S A (1981) 1.10

Genetic homologies among Streptomyces violaceoruber strains. J Bacteriol (1969) 1.09

A cellular function is required for pseudorabies virus envelope glycoprotein processing and virus egress. J Virol (1992) 1.09

The gE and gI homologs from two alphaherpesviruses have conserved and divergent neuroinvasive properties. J Virol (1997) 1.08

Frequent site-specific deletion of coliphage lambda murine sarcoma virus recombinants and its use in the identification of a retrovirus integration site. J Virol (1980) 1.08

Overexpression in bacterial and identification in infected cells of the pseudorabies virus protein homologous to herpes simplex virus type 1 ICP18.5. J Virol (1991) 1.07

The pseudorabies virus Us2 protein, a virion tegument component, is prenylated in infected cells. J Virol (2003) 1.04

The role of lambda integrase in integration and excision. Cold Spring Harb Symp Quant Biol (1979) 1.03

Isolation of novel herpes simplex virus type 1 derivatives with tandem duplications of DNA sequences encoding immediate-early mRNA-5 and an origin of replication. J Virol (1985) 1.02

Transneuronal circuit analysis with pseudorabies viruses. Curr Protoc Neurosci (2001) 0.99

Comparison of the pseudorabies virus Us9 protein with homologs from other veterinary and human alphaherpesviruses. J Virol (2009) 0.98