Extremes of Interferon-Stimulated Gene Expression Associate with Worse Outcomes in the Acute Respiratory Distress Syndrome.

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Published in PLoS One on September 08, 2016

Authors

Jerry A Nick1,2, Silvia M Caceres1, Jennifer E Kret3, Katie R Poch1, Matthew Strand4, Anna V Faino4, David P Nichols5, Milene T Saavedra1,2, Jennifer L Taylor-Cousar1,2, Mark W Geraci2, Ellen L Burnham2, Michael B Fessler6, Benjamin T Suratt7, Edward Abraham8, Marc Moss2, Kenneth C Malcolm1,2

Author Affiliations

1: Department of Medicine, National Jewish Health, Denver, Colorado, United States of America.
2: Division of Pulmonary Science and Critical Care Medicine, Department of Medicine, University of Colorado Denver School of Medicine, Aurora, Colorado, United States of America.
3: St Louis County Department of Public Health, Berkeley, Missouri, United States of America.
4: Division of Biostatistics and Bioinformatics, National Jewish Health, Denver, Colorado, United States of America.
5: Department of Pediatrics, National Jewish Health, Denver, Colorado, United States of America.
6: Immunity, Inflammation, and Disease Laboratory, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, North Carolina, United States of America.
7: Department of Medicine, University of Vermont College of Medicine, Burlington, Vermont, United States of America.
8: Office of the Dean, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America.

Associated clinical trials:

Statins for Acutely Injured Lungs From Sepsis (SAILS) | NCT00979121

Early Versus Delayed Enteral Feeding and Omega-3 Fatty Acid/Antioxidant Supplementation for Treating People With Acute Lung Injury or Acute Respiratory Distress Syndrome (The EDEN-Omega Study) (EDEN-Omega) | NCT00609180

Drug Study of Albuterol to Treat Acute Lung Injury (ALTA) | NCT00434993

Early Versus Delayed Enteral Feeding to Treat People With Acute Lung Injury or Acute Respiratory Distress Syndrome (The EDEN Study) (EDEN) | NCT00883948

Viral-Related Neutrophil Response and Condition Severity in People With ARDS | NCT00548795

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