Association between GABRA1 and drinking behaviors in the collaborative study on the genetics of alcoholism sample.

PubWeight™: 1.39‹?› | Rank: Top 5%

🔗 View Article (PMID 16792556)

Published in Alcohol Clin Exp Res on July 01, 2006

Authors

Danielle M Dick1, Jevon Plunkett, Leah Flury Wetherill, Xiaoling Xuei, Alison Goate, Victor Hesselbrock, Marc Schuckit, Raymond Crowe, Howard J Edenberg, Tatiana Foroud

Author Affiliations

1: Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri 63110, USA. dickd@wustl.edu

Articles citing this

Genome-wide association study of alcohol dependence implicates a region on chromosome 11. Alcohol Clin Exp Res (2010) 2.99

Beyond classical benzodiazepines: novel therapeutic potential of GABAA receptor subtypes. Nat Rev Drug Discov (2011) 2.65

Neuropharmacology of alcohol addiction. Br J Pharmacol (2008) 2.65

The role of GABA(A) receptors in the acute and chronic effects of ethanol: a decade of progress. Psychopharmacology (Berl) (2009) 2.50

The role of GABA(A) receptors in the development of alcoholism. Pharmacol Biochem Behav (2008) 1.82

Molecular genetics of addiction and related heritable phenotypes: genome-wide association approaches identify "connectivity constellation" and drug target genes with pleiotropic effects. Ann N Y Acad Sci (2008) 1.69

Binge alcohol drinking is associated with GABAA alpha2-regulated Toll-like receptor 4 (TLR4) expression in the central amygdala. Proc Natl Acad Sci U S A (2011) 1.31

"Higher order" addiction molecular genetics: convergent data from genome-wide association in humans and mice. Biochem Pharmacol (2007) 1.22

Genetic and environmental risk factors for adolescent-onset substance use disorders. Child Adolesc Psychiatr Clin N Am (2010) 1.06

Pharmacogenetics of alcohol and alcohol dependence treatment. Curr Pharm Des (2010) 1.05

Association of gamma-aminobutyric acid A receptor α2 gene (GABRA2) with alcohol use disorder. Neuropsychopharmacology (2013) 0.99

Associations among GABRG1, level of response to alcohol, and drinking behaviors. Alcohol Clin Exp Res (2009) 0.98

A comparison of selected quantitative trait loci associated with alcohol use phenotypes in humans and mouse models. Addict Biol (2010) 0.98

How adaptation of the brain to alcohol leads to dependence: a pharmacological perspective. Alcohol Res Health (2008) 0.96

Candidate genes for alcohol preference identified by expression profiling in alcohol-preferring and -nonpreferring reciprocal congenic rats. Genome Biol (2010) 0.96

The genetics of alcohol and other drug dependence. Alcohol Res Health (2008) 0.93

GABAergic contributions to alcohol responsivity during adolescence: insights from preclinical and clinical studies. Pharmacol Ther (2014) 0.92

GABRR1 and GABRR2, encoding the GABA-A receptor subunits rho1 and rho2, are associated with alcohol dependence. Am J Med Genet B Neuropsychiatr Genet (2010) 0.92

Heritability and molecular-genetic basis of resting EEG activity: a genome-wide association study. Psychophysiology (2014) 0.92

The investigation into CYP2E1 in relation to the level of response to alcohol through a combination of linkage and association analysis. Alcohol Clin Exp Res (2010) 0.90

Binge Drinking: In Search of its Molecular Target via the GABA(A) Receptor. Front Neurosci (2011) 0.89

Addiction genetics and pleiotropic effects of common haplotypes that make polygenic contributions to vulnerability to substance dependence. J Neurogenet (2009) 0.88

Brain electrophysiological endophenotypes for externalizing psychopathology: a multivariate approach. Behav Genet (2010) 0.88

A brief history of research on the genetics of alcohol and other drug use disorders. J Stud Alcohol Drugs Suppl (2014) 0.88

Effect of homozygous deletions at 22q13.1 on alcohol dependence severity and cue-elicited BOLD response in the precuneus. Addict Biol (2011) 0.86

Genetic influences on alcohol use across stages of development: GABRA2 and longitudinal trajectories of drunkenness from adolescence to young adulthood. Addict Biol (2013) 0.86

Knowns and unknowns for psychophysiological endophenotypes: integration and response to commentaries. Psychophysiology (2014) 0.85

Genetic research: who is at risk for alcoholism. Alcohol Res Health (2010) 0.85

Genome-wide association study identifies 5q21 and 9p24.1 (KDM4C) loci associated with alcohol withdrawal symptoms. J Neural Transm (Vienna) (2011) 0.85

Effects of vigabatrin, an irreversible GABA transaminase inhibitor, on ethanol reinforcement and ethanol discriminative stimuli in mice. Behav Pharmacol (2012) 0.84

Stability of scores and correlations with drinking behaviors over 15 years for the Self-Report of the Effects of Alcohol Questionnaire. Drug Alcohol Depend (2012) 0.83

Genetically selected alcohol preferring rats to model human alcoholism. Curr Top Behav Neurosci (2013) 0.81

Candidate genes for alcohol dependence: A genetic association study from India. Indian J Med Res (2016) 0.80

ANKRD7 and CYTL1 are novel risk genes for alcohol drinking behavior. Chin Med J (Engl) (2012) 0.80

Altering the relative abundance of GABA A receptor subunits changes GABA- and ethanol-responses in Xenopus oocytes. Alcohol Clin Exp Res (2009) 0.79

Amygdala 14-3-3ζ as a novel modulator of escalating alcohol intake in mice. PLoS One (2012) 0.79

Alcohol-induced tolerance and physical dependence in mice with ethanol insensitive alpha1 GABA A receptors. Alcohol Clin Exp Res (2008) 0.79

Alcohol Dependence and Genes Encoding α2 and γ1 GABAA Receptor Subunits: Insights from Humans and Mice. Alcohol Res (2012) 0.78

GABA-A receptor genes do not play a role in genetics of Lesch's typology in Caucasian subjects. Arch Med Sci (2012) 0.77

A Genetic Animal Model of Alcoholism for Screening Medications to Treat Addiction. Int Rev Neurobiol (2016) 0.77

Neurotransmitters in alcoholism: A review of neurobiological and genetic studies. Indian J Hum Genet (2014) 0.75

Association between GABA(A) receptor subunit gene cluster and zolpidem-induced complex sleep behaviors in Han Chinese. Sleep (2013) 0.75

GABA Receptors Genes Polymorphisms and Alcohol Dependence: No Evidence of an Association in an Italian Male Population. Clin Psychopharmacol Neurosci (2014) 0.75

Need for power in genetic explorations of alcoholism in India. Indian J Med Res (2016) 0.75

miR-181a is a negative regulator of GRIA2 in methamphetamine-use disorder. Sci Rep (2016) 0.75

Articles by these authors

Clinical and biomarker changes in dominantly inherited Alzheimer's disease. N Engl J Med (2012) 14.14

TREM2 variants in Alzheimer's disease. N Engl J Med (2012) 11.35

Genome-wide association study reveals genetic risk underlying Parkinson's disease. Nat Genet (2009) 10.34

Common genetic determinants of vitamin D insufficiency: a genome-wide association study. Lancet (2010) 8.89

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet (2013) 8.02

Variants in nicotinic receptors and risk for nicotine dependence. Am J Psychiatry (2008) 6.73

Genomewide association study for susceptibility genes contributing to familial Parkinson disease. Hum Genet (2008) 5.04

Variations in GABRA2, encoding the alpha 2 subunit of the GABA(A) receptor, are associated with alcohol dependence and with brain oscillations. Am J Hum Genet (2004) 5.02

A genome-wide association study of alcohol dependence. Proc Natl Acad Sci U S A (2010) 4.94

Quality control and quality assurance in genotypic data for genome-wide association studies. Genet Epidemiol (2010) 4.83

Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database. PLoS Genet (2012) 4.27

Effects of filtering by Present call on analysis of microarray experiments. BMC Bioinformatics (2006) 3.86

Genetic screening for a single common LRRK2 mutation in familial Parkinson's disease. Lancet (2005) 3.63

Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nat Genet (2010) 3.37

Splicing factor SFRS1 recognizes a functionally diverse landscape of RNA transcripts. Genome Res (2008) 3.33

Whole genome association study of brain-wide imaging phenotypes for identifying quantitative trait loci in MCI and AD: A study of the ADNI cohort. Neuroimage (2010) 3.27

Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q. Am J Hum Genet (2005) 3.24

Allelic and haplotypic association of GABRA2 with alcohol dependence. Am J Med Genet B Neuropsychiatr Genet (2004) 3.10

Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorder. Am J Hum Genet (2003) 3.02

Genome-wide association study of alcohol dependence implicates a region on chromosome 11. Alcohol Clin Exp Res (2010) 2.99

APOE4 allele disrupts resting state fMRI connectivity in the absence of amyloid plaques or decreased CSF Aβ42. J Neurosci (2010) 2.99

Genetics of osteoporosis. Endocr Rev (2002) 2.91

DSM-5 criteria for substance use disorders: recommendations and rationale. Am J Psychiatry (2013) 2.89

Evidence for novel susceptibility genes for late-onset Alzheimer's disease from a genome-wide association study of putative functional variants. Hum Mol Genet (2007) 2.73

Voxelwise genome-wide association study (vGWAS). Neuroimage (2010) 2.69

Nicotinic receptor gene variants influence susceptibility to heavy smoking. Cancer Epidemiol Biomarkers Prev (2008) 2.58

Genomewide linkage analyses of bipolar disorder: a new sample of 250 pedigrees from the National Institute of Mental Health Genetics Initiative. Am J Hum Genet (2003) 2.55

Association of alcohol dehydrogenase genes with alcohol dependence: a comprehensive analysis. Hum Mol Genet (2006) 2.49

Linkage disequilibrium between the beta frequency of the human EEG and a GABAA receptor gene locus. Proc Natl Acad Sci U S A (2002) 2.47

Evidence of common and specific genetic effects: association of the muscarinic acetylcholine receptor M2 (CHRM2) gene with alcohol dependence and major depressive syndrome. Hum Mol Genet (2004) 2.47

Changes in gene expression during pegylated interferon and ribavirin therapy of chronic hepatitis C virus distinguish responders from nonresponders to antiviral therapy. J Virol (2007) 2.45

Murine embryonic stem cell differentiation is promoted by SOCS-3 and inhibited by the zinc finger transcription factor Klf4. Blood (2004) 2.35

A multicenter study of glucocerebrosidase mutations in dementia with Lewy bodies. JAMA Neurol (2013) 2.32

Clearance of amyloid-beta by circulating lipoprotein receptors. Nat Med (2007) 2.32

The role of GABRA2 in risk for conduct disorder and alcohol and drug dependence across developmental stages. Behav Genet (2006) 2.26

Genomewide linkage scan for cocaine dependence and related traits: significant linkages for a cocaine-related trait and cocaine-induced paranoia. Am J Med Genet B Neuropsychiatr Genet (2005) 2.24

Meta-analysis of Parkinson's disease: identification of a novel locus, RIT2. Ann Neurol (2012) 2.20

Genomewide linkage scan for opioid dependence and related traits. Am J Hum Genet (2006) 2.15

The genetics of alcoholism: identifying specific genes through family studies. Addict Biol (2006) 2.12

A commonly carried allele of the obesity-related FTO gene is associated with reduced brain volume in the healthy elderly. Proc Natl Acad Sci U S A (2010) 2.12

Pooled association genome scanning for alcohol dependence using 104,268 SNPs: validation and use to identify alcoholism vulnerability loci in unrelated individuals from the collaborative study on the genetics of alcoholism. Am J Med Genet B Neuropsychiatr Genet (2006) 2.09

Linkage and linkage disequilibrium mapping of ERP and EEG phenotypes. Biol Psychol (2002) 2.08

A family study of alcohol dependence: coaggregation of multiple disorders in relatives of alcohol-dependent probands. Arch Gen Psychiatry (2004) 2.06

A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. Am J Hum Genet (2005) 2.04

Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption. Proc Natl Acad Sci U S A (2011) 2.01

Translation initiator EIF4G1 mutations in familial Parkinson disease. Am J Hum Genet (2011) 2.00

Global effect of PEG-IFN-alpha and ribavirin on gene expression in PBMC in vitro. J Interferon Cytokine Res (2004) 1.98

Association of late-onset Alzheimer's disease with genetic variation in multiple members of the GAPD gene family. Proc Natl Acad Sci U S A (2004) 1.95

Genome-wide analysis reveals novel genes influencing temporal lobe structure with relevance to neurodegeneration in Alzheimer's disease. Neuroimage (2010) 1.94

Genome screen to identify susceptibility genes for Parkinson disease in a sample without parkin mutations. Am J Hum Genet (2002) 1.93

A presenilin dimer at the core of the gamma-secretase enzyme: insights from parallel analysis of Notch 1 and APP proteolysis. Proc Natl Acad Sci U S A (2003) 1.92

Death-associated protein kinase 1 phosphorylates Pin1 and inhibits its prolyl isomerase activity and cellular function. Mol Cell (2011) 1.90

The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data. Brain Imaging Behav (2014) 1.90

A genomic scan for habitual smoking in families of alcoholics: common and specific genetic factors in substance dependence. Am J Med Genet A (2004) 1.88

A risk allele for nicotine dependence in CHRNA5 is a protective allele for cocaine dependence. Biol Psychiatry (2008) 1.88

Association of GABRA2 with drug dependence in the collaborative study of the genetics of alcoholism sample. Behav Genet (2006) 1.87

Candidate genes for alcohol dependence: a review of genetic evidence from human studies. Alcohol Clin Exp Res (2003) 1.85

Linkage and linkage disequilibrium of evoked EEG oscillations with CHRM2 receptor gene polymorphisms: implications for human brain dynamics and cognition. Int J Psychophysiol (2004) 1.79