Genetics of osteoporosis.

PubWeight™: 2.91‹?› | Rank: Top 1%

🔗 View Article (PMID 12050122)

Published in Endocr Rev on June 01, 2002

Authors

Munro Peacock1, Charles H Turner, Michael J Econs, Tatiana Foroud

Author Affiliations

1: Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA. mpeacock@iupui.edu

Articles citing this

(truncated to the top 100)

Five years of GWAS discovery. Am J Hum Genet (2012) 12.97

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nat Genet (2012) 5.48

Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies. Nat Genet (2009) 5.32

New sequence variants associated with bone mineral density. Nat Genet (2008) 3.43

African Americans, 25-hydroxyvitamin D, and osteoporosis: a paradox. Am J Clin Nutr (2008) 2.37

Polymorphisms in the low-density lipoprotein receptor-related protein 5 (LRP5) gene are associated with variation in vertebral bone mass, vertebral bone size, and stature in whites. Am J Hum Genet (2004) 1.97

The continuing value of twin studies in the omics era. Nat Rev Genet (2012) 1.88

Linkage of osteoporosis to chromosome 20p12 and association to BMP2. PLoS Biol (2003) 1.64

Use of multivariate linkage analysis for dissection of a complex cognitive trait. Am J Hum Genet (2003) 1.62

Molecular genetic studies of gene identification for osteoporosis: a 2004 update. J Bone Miner Res (2006) 1.52

Wnt signaling in bone metabolism. J Bone Miner Metab (2009) 1.48

Quantitative trait loci for bone mineral density and femoral morphology in an advanced intercross population of mice. Bone (2013) 1.40

Genome-wide association study of bone mineral density in premenopausal European-American women and replication in African-American women. J Clin Endocrinol Metab (2010) 1.30

European bone mineral density loci are also associated with BMD in East-Asian populations. PLoS One (2010) 1.29

Varying coefficient model for gene-environment interaction: a non-linear look. Bioinformatics (2011) 1.29

Genetic variation at the low-density lipoprotein receptor-related protein 5 (LRP5) locus modulates Wnt signaling and the relationship of physical activity with bone mineral density in men. Bone (2006) 1.27

Peak bone mineral density at the hip is linked to chromosomes 14q and 15q. Osteoporos Int (2004) 1.17

Multistage genome-wide association meta-analyses identified two new loci for bone mineral density. Hum Mol Genet (2013) 1.17

Genome screen for bone mineral density phenotypes in Fisher 344 and Lewis rat strains. Mamm Genome (2005) 1.10

Genome-wide pleiotropy of osteoporosis-related phenotypes: the Framingham Study. J Bone Miner Res (2010) 1.09

Association between a variation in the phosphodiesterase 4D gene and bone mineral density. BMC Med Genet (2005) 1.05

Weight-bearing bones are more sensitive to physical exercise in boys than in girls during pre- and early puberty: a cross-sectional study. Osteoporos Int (2008) 1.05

Confirmation of linkage to chromosome 1q for peak vertebral bone mineral density in premenopausal white women. Am J Hum Genet (2004) 1.04

Association analysis of estrogen receptor alpha gene polymorphisms with cross-sectional geometry of the femoral neck in Caucasian nuclear families. Osteoporos Int (2005) 1.03

Sex-specific quantitative trait loci contribute to normal variation in bone structure at the proximal femur in men. Bone (2005) 1.01

A novel method for identifying nonlinear gene-environment interactions in case-control association studies. Hum Genet (2013) 1.00

Epistatic effects contribute to variation in BMD in Fischer 344 x Lewis F2 rats. J Bone Miner Res (2008) 0.98

Multiscale mechanical simulations of cell compacted collagen gels. J Biomech Eng (2013) 0.95

A functional haplotype in EIF2AK3, an ER stress sensor, is associated with lower bone mineral density. J Bone Miner Res (2012) 0.93

Genome-wide association of an integrated osteoporosis-related phenotype: is there evidence for pleiotropic genes? J Bone Miner Res (2012) 0.92

Common variants in a novel gene, FONG on chromosome 2q33.1 confer risk of osteoporosis in Japanese. PLoS One (2011) 0.92

Inhibition of the progesterone nuclear receptor during the bone linear growth phase increases peak bone mass in female mice. PLoS One (2010) 0.92

A look behind the scenes: the risk and pathogenesis of primary osteoporosis. Nat Rev Rheumatol (2015) 0.90

Bone mineral density variation in men is influenced by sex-specific and non sex-specific quantitative trait loci. Bone (2009) 0.90

Linkage screen for BMD phenotypes in male and female COP and DA rat strains. J Bone Miner Res (2008) 0.89

Polymorphisms in the estrogen receptor beta (ESR2) gene are associated with bone mineral density in Caucasian men and women. J Clin Endocrinol Metab (2005) 0.88

Association of alpha2-HS glycoprotein (AHSG, fetuin-A) polymorphism with AHSG and phosphate serum levels. Hum Genet (2004) 0.88

Integrating Epigenomic Elements and GWASs Identifies BDNF Gene Affecting Bone Mineral Density and Osteoporotic Fracture Risk. Sci Rep (2016) 0.88

Replication of previous genome-wide association studies of bone mineral density in premenopausal American women. J Bone Miner Res (2010) 0.87

Sex-specific genetic loci for femoral neck bone mass and strength identified in inbred COP and DA rats. J Bone Miner Res (2008) 0.87

Meta-analysis identifies a MECOM gene as a novel predisposing factor of osteoporotic fracture. J Med Genet (2013) 0.86

Genetic polymorphisms are associated with serum levels of sex hormone binding globulin in postmenopausal women. BMC Med Genet (2008) 0.85

Genetic and environmental factors in human osteoporosis from Sub-Saharan to Mediterranean areas. J Bone Miner Metab (2009) 0.85

Velocities of bone mineral accrual in black and white American children. J Bone Miner Res (2010) 0.84

Prospective study of physical activity and risk of developing a stress fracture among preadolescent and adolescent girls. Arch Pediatr Adolesc Med (2011) 0.84

Vitamin D receptor gene BsmI polymorphisms in Thai patients with systemic lupus erythematosus. Arthritis Res Ther (2006) 0.84

ALOX12 polymorphisms are associated with fat mass but not peak bone mineral density in Chinese nuclear families. Int J Obes (Lond) (2010) 0.84

Bone mineral density and osteoporosis after preterm birth: the role of early life factors and nutrition. Int J Endocrinol (2013) 0.84

Identification of quantitative trait loci influencing skeletal architecture in mice: emergence of Cdh11 as a primary candidate gene regulating femoral morphology. J Bone Miner Res (2011) 0.83

Do epigenetic marks govern bone mass and homeostasis? Curr Genomics (2012) 0.83

Contribution of the sclerostin domain-containing protein 1 (SOSTDC1) gene to normal variation of peak bone mineral density in Chinese women and men. J Bone Miner Metab (2011) 0.83

Associations of catalase gene polymorphisms with bone mineral density and bone turnover markers in postmenopausal women. J Med Genet (2007) 0.82

A single nucleotide polymorphism in osteonectin 3' untranslated region regulates bone volume and is targeted by miR-433. J Bone Miner Res (2015) 0.81

SIBLING family genes and bone mineral density: association and allele-specific expression in humans. Bone (2014) 0.81

Cortical bone health shows significant linkage to chromosomes 2p, 3p, and 17q in 10-year-old children. Bone (2011) 0.81

Heritability of impaired balance: a nationwide cohort study in twins. Osteoporos Int (2008) 0.81

Association of adenylate cyclase 10 (ADCY10) polymorphisms and bone mineral density in healthy adults. Calcif Tissue Int (2008) 0.81

Association of aromatase and estrogen receptor gene polymorphisms with hip fractures. Osteoporos Int (2008) 0.81

Pubertal timing and body mass index gain from birth to maturity in relation with femoral neck BMD and distal tibia microstructure in healthy female subjects. Osteoporos Int (2011) 0.81

Skeletal site-related variation in human trabecular bone transcriptome and signaling. PLoS One (2010) 0.81

Systems genetics: a novel approach to dissect the genetic basis of osteoporosis. Curr Osteoporos Rep (2012) 0.81

Association between vitamin D receptor gene polymorphisms (Fok1 and Bsm1) and osteoporosis: a systematic review. J Diabetes Metab Disord (2014) 0.81

On genetic studies of bone loss. J Bone Miner Res (2006) 0.80

Functional significance of genetic variation underlying limb bone diaphyseal structure. Am J Phys Anthropol (2010) 0.80

Genetic influence on bone phenotypes and body composition: a Swedish twin study. J Bone Miner Metab (2013) 0.80

Epistasis between QTLs for bone density variation in Copenhagen x dark agouti F2 rats. Mamm Genome (2009) 0.80

Family-based association study of ROR2 polymorphisms with an array of radiographic hand bone strength phenotypes. Osteoporos Int (2007) 0.80

Nucleotide variations in genes encoding carbonic anhydrase 8 and 10 associated with femoral bone mineral density in Japanese female with osteoporosis. J Bone Miner Metab (2009) 0.80

Predicting fracture using 2D finite element modelling. Med Eng Phys (2011) 0.79

Association studies of ALOX5 and bone mineral density in healthy adults. Osteoporos Int (2007) 0.79

Clinical impact of recent genetic discoveries in osteoporosis. Appl Clin Genet (2013) 0.79

Skeletal growth and the changing genetic landscape during childhood and adulthood. Am J Phys Anthropol (2013) 0.79

Polymorphisms in the bone morphogenetic protein 2 (BMP2) gene do not affect bone mineral density in white men or women. Osteoporos Int (2006) 0.79

The role of genetics in estrogen responses: a critical piece of an intricate puzzle. FASEB J (2014) 0.78

Identification of a linkage disequilibrium block in chromosome 1q associated with BMD in premenopausal white women. J Bone Miner Res (2008) 0.78

Fracture, bone mineral density, and the effects of calcitonin receptor gene in postmenopausal Koreans. Osteoporos Int (2009) 0.78

Cooperative effect of serum 25-hydroxyvitamin D concentration and a polymorphism of transforming growth factor-beta1 gene on the prevalence of vertebral fractures in postmenopausal osteoporosis. J Bone Miner Metab (2010) 0.78

Identification of candidate gene regions in the rat by co-localization of QTLs for bone density, size, structure and strength. PLoS One (2011) 0.78

Limited clinical utility of a genetic risk score for the prediction of fracture risk in elderly subjects. J Bone Miner Res (2015) 0.78

Identification of a novel FGFRL1 MicroRNA target site polymorphism for bone mineral density in meta-analyses of genome-wide association studies. Hum Mol Genet (2015) 0.78

Strong association between polymorphisms in ANKH locus and skeletal size traits. Hum Genet (2006) 0.78

Genetic risk score based on the lifetime prevalence of femoral fracture in 924 consecutive autopsies of Japanese males. J Bone Miner Metab (2015) 0.77

Lack of association of bone morphogenetic protein 2 gene haplotypes with bone mineral density, bone loss, or risk of fractures in men. J Osteoporos (2011) 0.77

A Follow-up Association Study of Genetic Variants for Bone Mineral Density in a Korean Population. Genomics Inform (2014) 0.77

Bone quality in osteopenic postmenopausal women is not improved after 12 months of whole-body vibration training. Osteoporos Int (2015) 0.77

Association of SMAD2 polymorphisms with bone mineral density in postmenopausal Korean women. Osteoporos Int (2010) 0.77

Association between estrogen receptor-β dinucleotide repeat polymorphism and incidence of femoral fracture. J Bone Miner Metab (2012) 0.77

Genetic analysis identifies DDR2 as a novel gene affecting bone mineral density and osteoporotic fractures in Chinese population. PLoS One (2015) 0.77

Genetic markers of bone and joint health and physical capability in older adults: the HALCyon programme. Bone (2012) 0.77

Genome-wide Survey of Runs of Homozygosity Identifies Recessive Loci for Bone Mineral Density in Caucasian and Chinese Populations. J Bone Miner Res (2015) 0.77

Common genetic variants are associated with accelerated bone mineral density loss after hematopoietic cell transplantation. PLoS One (2011) 0.76

Association of microstructural and mechanical properties of cancellous bone and their fracture risk assessment tool scores. Int J Clin Exp Med (2015) 0.75

Genome-wide association meta-analyses identified 1q43 and 2q32.2 for hip Ward's triangle areal bone mineral density. Bone (2016) 0.75

Limited Trabecular Bone Density Heterogeneity in the Human Skeleton. Anat Res Int (2016) 0.75

Genome-Wide Association Study of Bone Mineral Density in Korean Men. Genomics Inform (2016) 0.75

Premenopausal Trabecular Bone Loss is Associated with a Family History of Fragility Fracture. Geburtshilfe Frauenheilkd (2016) 0.75

CLCN7 polymorphisms and bone mineral density in healthy premenopausal white women and in white men. Bone (2008) 0.75

Deficiency of ATP6V1H Causes Bone Loss by Inhibiting Bone Resorption and Bone Formation through the TGF-β1 Pathway. Theranostics (2016) 0.75

Genetic Contribution of Femoral Neck Bone Geometry to the Risk of Developing Osteoporosis: A Family-Based Study. PLoS One (2016) 0.75

Genetic risk score based on the prevalence of vertebral fracture in Japanese women with osteoporosis. Bone Rep (2016) 0.75

Articles by these authors

Common genetic determinants of vitamin D insufficiency: a genome-wide association study. Lancet (2010) 8.89

Fibroblast growth factor 23 in oncogenic osteomalacia and X-linked hypophosphatemia. N Engl J Med (2003) 8.87

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet (2013) 8.02

Variants in nicotinic receptors and risk for nicotine dependence. Am J Psychiatry (2008) 6.73

CD44+/CD24- breast cancer cells exhibit enhanced invasive properties: an early step necessary for metastasis. Breast Cancer Res (2006) 6.35

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nat Genet (2012) 5.48

Genomewide association study for susceptibility genes contributing to familial Parkinson disease. Hum Genet (2008) 5.04

Variations in GABRA2, encoding the alpha 2 subunit of the GABA(A) receptor, are associated with alcohol dependence and with brain oscillations. Am J Hum Genet (2004) 5.02

A genome-wide association study of alcohol dependence. Proc Natl Acad Sci U S A (2010) 4.94

Mechanical stimulation of bone in vivo reduces osteocyte expression of Sost/sclerostin. J Biol Chem (2007) 4.74

Bone loss and bone size after menopause. N Engl J Med (2003) 4.64

Most osteomalacia-associated mesenchymal tumors are a single histopathologic entity: an analysis of 32 cases and a comprehensive review of the literature. Am J Surg Pathol (2004) 4.46

Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database. PLoS Genet (2012) 4.27

Genetic screening for a single common LRRK2 mutation in familial Parkinson's disease. Lancet (2005) 3.63

FGF-23 in fibrous dysplasia of bone and its relationship to renal phosphate wasting. J Clin Invest (2003) 3.60

Biomechanical and molecular regulation of bone remodeling. Annu Rev Biomed Eng (2006) 3.46

Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nat Genet (2010) 3.37

Whole genome association study of brain-wide imaging phenotypes for identifying quantitative trait loci in MCI and AD: A study of the ADNI cohort. Neuroimage (2010) 3.27

Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q. Am J Hum Genet (2005) 3.24

The Wnt co-receptor LRP5 is essential for skeletal mechanotransduction but not for the anabolic bone response to parathyroid hormone treatment. J Biol Chem (2006) 3.04

Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorder. Am J Hum Genet (2003) 3.02

Genome-wide association study of alcohol dependence implicates a region on chromosome 11. Alcohol Clin Exp Res (2010) 2.99

Control of bone mass and remodeling by PTH receptor signaling in osteocytes. PLoS One (2008) 2.96

A homozygous missense mutation in human KLOTHO causes severe tumoral calcinosis. J Clin Invest (2007) 2.79

Voxelwise genome-wide association study (vGWAS). Neuroimage (2010) 2.69

Genomewide linkage analyses of bipolar disorder: a new sample of 250 pedigrees from the National Institute of Mental Health Genetics Initiative. Am J Hum Genet (2003) 2.55

Association of alcohol dehydrogenase genes with alcohol dependence: a comprehensive analysis. Hum Mol Genet (2006) 2.49

Linkage disequilibrium between the beta frequency of the human EEG and a GABAA receptor gene locus. Proc Natl Acad Sci U S A (2002) 2.47

A multicenter study of glucocerebrosidase mutations in dementia with Lewy bodies. JAMA Neurol (2013) 2.32

A novel GALNT3 mutation in a pseudoautosomal dominant form of tumoral calcinosis: evidence that the disorder is autosomal recessive. J Clin Endocrinol Metab (2005) 2.30

The role of GABRA2 in risk for conduct disorder and alcohol and drug dependence across developmental stages. Behav Genet (2006) 2.26

Meta-analysis of Parkinson's disease: identification of a novel locus, RIT2. Ann Neurol (2012) 2.20

Establishment of sandwich ELISA for soluble alpha-Klotho measurement: Age-dependent change of soluble alpha-Klotho levels in healthy subjects. Biochem Biophys Res Commun (2010) 2.20

The genetics of alcoholism: identifying specific genes through family studies. Addict Biol (2006) 2.12

A commonly carried allele of the obesity-related FTO gene is associated with reduced brain volume in the healthy elderly. Proc Natl Acad Sci U S A (2010) 2.12

Pooled association genome scanning for alcohol dependence using 104,268 SNPs: validation and use to identify alcoholism vulnerability loci in unrelated individuals from the collaborative study on the genetics of alcoholism. Am J Med Genet B Neuropsychiatr Genet (2006) 2.09

Improved bone structure and strength after long-term mechanical loading is greatest if loading is separated into short bouts. J Bone Miner Res (2002) 2.08

Inhibition of the serotonin (5-hydroxytryptamine) transporter reduces bone accrual during growth. Endocrinology (2004) 2.02

Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption. Proc Natl Acad Sci U S A (2011) 2.01

Translation initiator EIF4G1 mutations in familial Parkinson disease. Am J Hum Genet (2011) 2.00

Sost downregulation and local Wnt signaling are required for the osteogenic response to mechanical loading. Bone (2011) 1.96

Genome-wide analysis reveals novel genes influencing temporal lobe structure with relevance to neurodegeneration in Alzheimer's disease. Neuroimage (2010) 1.94

Genome screen to identify susceptibility genes for Parkinson disease in a sample without parkin mutations. Am J Hum Genet (2002) 1.93

Mutations that cause osteoglophonic dysplasia define novel roles for FGFR1 in bone elongation. Am J Hum Genet (2004) 1.92

Sensitivity of fibroblast growth factor 23 measurements in tumor-induced osteomalacia. J Clin Endocrinol Metab (2006) 1.91

The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data. Brain Imaging Behav (2014) 1.90

A genomic scan for habitual smoking in families of alcoholics: common and specific genetic factors in substance dependence. Am J Med Genet A (2004) 1.88

Association of GABRA2 with drug dependence in the collaborative study of the genetics of alcoholism sample. Behav Genet (2006) 1.87

Candidate genes for alcohol dependence: a review of genetic evidence from human studies. Alcohol Clin Exp Res (2003) 1.85

The effects of dynamic axial loading on the rat growth plate. J Bone Miner Res (2002) 1.82

The P2X7 nucleotide receptor mediates skeletal mechanotransduction. J Biol Chem (2005) 1.81

Linkage and linkage disequilibrium of evoked EEG oscillations with CHRM2 receptor gene polymorphisms: implications for human brain dynamics and cognition. Int J Psychophysiol (2004) 1.79

FGF23 is processed by proprotein convertases but not by PHEX. Bone (2004) 1.79

Predicting sensation seeking from dopamine genes. A candidate-system approach. Psychol Sci (2010) 1.78

Iron modifies plasma FGF23 differently in autosomal dominant hypophosphatemic rickets and healthy humans. J Clin Endocrinol Metab (2011) 1.75

Cinacalcet hydrochloride maintains long-term normocalcemia in patients with primary hyperparathyroidism. J Clin Endocrinol Metab (2004) 1.71

Screening for brain aneurysm in the Familial Intracranial Aneurysm study: frequency and predictors of lesion detection. J Neurosurg (2008) 1.68

Copy-number disorders are a common cause of congenital kidney malformations. Am J Hum Genet (2012) 1.63

The roles of specific genes implicated as circulating factors involved in normal and disordered phosphate homeostasis: frizzled related protein-4, matrix extracellular phosphoglycoprotein, and fibroblast growth factor 23. Endocr Rev (2006) 1.58

Dentin matrix protein 1 gene cis-regulation: use in osteocytes to characterize local responses to mechanical loading in vitro and in vivo. J Biol Chem (2005) 1.57

Effects of raloxifene on bone density, biomarkers, and histomorphometric and biomechanical measures in ovariectomized cynomolgus monkeys. Menopause (2002) 1.55

Mapping quantitative trait loci for vertebral trabecular bone volume fraction and microarchitecture in mice. J Bone Miner Res (2003) 1.52

Functional variant in a bitter-taste receptor (hTAS2R16) influences risk of alcohol dependence. Am J Hum Genet (2005) 1.49

Intronic deletions in the SLC34A3 gene cause hereditary hypophosphatemic rickets with hypercalciuria. J Clin Endocrinol Metab (2006) 1.49

Voxelwise gene-wide association study (vGeneWAS): multivariate gene-based association testing in 731 elderly subjects. Neuroimage (2011) 1.48

Association of GABA(A) receptors and alcohol dependence and the effects of genetic imprinting. Am J Med Genet B Neuropsychiatr Genet (2003) 1.47

Genome-wide linkage analysis and evidence of gene-by-gene interactions in a sample of 362 multiplex Parkinson disease families. Hum Mol Genet (2003) 1.47

A model for mechanotransduction in bone cells: the load-bearing mechanosomes. J Cell Biochem (2003) 1.45

Linkage mapping of beta 2 EEG waves via non-parametric regression. Am J Med Genet B Neuropsychiatr Genet (2003) 1.45

Measurement invariance of DSM-IV alcohol, marijuana and cocaine dependence between community-sampled and clinically overselected studies. Addiction (2013) 1.45

The Familial Intracranial Aneurysm (FIA) study protocol. BMC Med Genet (2005) 1.45

Analyses of the National Institute on Aging Late-Onset Alzheimer's Disease Family Study: implication of additional loci. Arch Neurol (2008) 1.44

Marital status, alcohol dependence, and GABRA2: evidence for gene-environment correlation and interaction. J Stud Alcohol (2006) 1.42

Exercise when young provides lifelong benefits to bone structure and strength. J Bone Miner Res (2007) 1.40

Association between GABRA1 and drinking behaviors in the collaborative study on the genetics of alcoholism sample. Alcohol Clin Exp Res (2006) 1.39

Genetic effects for femoral biomechanics, structure, and density in C57BL/6J and C3H/HeJ inbred mouse strains. J Bone Miner Res (2003) 1.37

Ablation of the Galnt3 gene leads to low-circulating intact fibroblast growth factor 23 (Fgf23) concentrations and hyperphosphatemia despite increased Fgf23 expression. Endocrinology (2009) 1.37

FGF23 concentrations vary with disease status in autosomal dominant hypophosphatemic rickets. J Bone Miner Res (2007) 1.36

Unique facial features distinguish fetal alcohol syndrome patients and controls in diverse ethnic populations. Alcohol Clin Exp Res (2007) 1.35

Collaborative initiative on fetal alcohol spectrum disorders: methodology of clinical projects. Alcohol (2009) 1.34

Mechanical signaling for bone modeling and remodeling. Crit Rev Eukaryot Gene Expr (2009) 1.33

Gene expression patterns in bone following mechanical loading. J Bone Miner Res (2011) 1.32

Endophenotypes successfully lead to gene identification: results from the collaborative study on the genetics of alcoholism. Behav Genet (2005) 1.32

The use of micro-CT to evaluate cortical bone geometry and strength in nude rats: correlation with mechanical testing, pQCT and DXA. Bone (2005) 1.32

Treatment of X-linked hypophosphatemia with calcitriol and phosphate increases circulating fibroblast growth factor 23 concentrations. J Clin Endocrinol Metab (2010) 1.31

Clinical variability of familial tumoral calcinosis caused by novel GALNT3 mutations. Am J Med Genet A (2010) 1.30

Combined sequence-based and genetic mapping analysis of complex traits in outbred rats. Nat Genet (2013) 1.30

Genome-wide association study of bone mineral density in premenopausal European-American women and replication in African-American women. J Clin Endocrinol Metab (2010) 1.30

Suggestive linkage on chromosome 1 for a quantitative alcohol-related phenotype. Alcohol Clin Exp Res (2002) 1.29

A variant in XPNPEP2 is associated with angioedema induced by angiotensin I-converting enzyme inhibitors. Am J Hum Genet (2005) 1.29

Association of GABRG3 with alcohol dependence. Alcohol Clin Exp Res (2004) 1.28

Generation of a new congenic mouse strain to test the relationships among serum insulin-like growth factor I, bone mineral density, and skeletal morphology in vivo. J Bone Miner Res (2002) 1.28

Defining alcohol-related phenotypes in humans. The Collaborative Study on the Genetics of Alcoholism. Alcohol Res Health (2002) 1.27

A comparison of mechanical properties derived from multiple skeletal sites in mice. J Biomech (2005) 1.27

Fibroblast growth factor 23: roles in health and disease. J Am Soc Nephrol (2005) 1.27

Sclerostin: a gem from the genome leads to bone-building antibodies. J Bone Miner Res (2010) 1.26