Published in J Clin Endocrinol Metab on June 27, 2006
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Fetal loss associated with excess thyroid hormone exposure. JAMA (2004) 3.03
A novel syndrome combining thyroid and neurological abnormalities is associated with mutations in a monocarboxylate transporter gene. Am J Hum Genet (2003) 2.80
Mutations in SECISBP2 result in abnormal thyroid hormone metabolism. Nat Genet (2005) 2.69
Tissue-specific thyroid hormone deprivation and excess in monocarboxylate transporter (mct) 8-deficient mice. Endocrinology (2006) 2.56
Generation of functional thyroid from embryonic stem cells. Nature (2012) 2.33
Targeted expression of BRAFV600E in thyroid cells of transgenic mice results in papillary thyroid cancers that undergo dedifferentiation. Cancer Res (2005) 2.23
Syndromes of reduced sensitivity to thyroid hormone: genetic defects in hormone receptors, cell transporters and deiodination. Best Pract Res Clin Endocrinol Metab (2007) 2.13
Identification of the maturation factor for dual oxidase. Evolution of an eukaryotic operon equivalent. J Biol Chem (2006) 2.08
Small-molecule MAPK inhibitors restore radioiodine incorporation in mouse thyroid cancers with conditional BRAF activation. J Clin Invest (2011) 1.97
Diiodothyropropionic acid (DITPA) in the treatment of MCT8 deficiency. J Clin Endocrinol Metab (2012) 1.85
Thyrotrophin receptor signaling dependence of Braf-induced thyroid tumor initiation in mice. Proc Natl Acad Sci U S A (2011) 1.82
Partial deficiency of thyroid transcription factor 1 produces predominantly neurological defects in humans and mice. J Clin Invest (2002) 1.76
Oncogenic Kras requires simultaneous PI3K signaling to induce ERK activation and transform thyroid epithelial cells in vivo. Cancer Res (2009) 1.65
Research funding. Science funding and short-term economic activity. Science (2014) 1.57
Steroid-induced diabetes: a clinical and molecular approach to understanding and treatment. Diabetes Metab Res Rev (2014) 1.55
The relationship between premature ejaculation and hyperthyroidism. J Urol (2009) 1.50
Thyroid hormone induces rapid activation of Akt/protein kinase B-mammalian target of rapamycin-p70S6K cascade through phosphatidylinositol 3-kinase in human fibroblasts. Mol Endocrinol (2004) 1.45
Transsphenoidal surgery for Cushing disease: experience with 136 patients. Neurosurgery (2012) 1.44
American Thyroid Association Guide to investigating thyroid hormone economy and action in rodent and cell models. Thyroid (2013) 1.41
Biallelic inactivation of the dual oxidase maturation factor 2 (DUOXA2) gene as a novel cause of congenital hypothyroidism. J Clin Endocrinol Metab (2007) 1.41
Predictive value of cardiothoracic ratio as a marker of severity of aortic regurgitation and mitral regurgitation. Anadolu Kardiyol Derg (2007) 1.38
The syndromes of reduced sensitivity to thyroid hormone. Biochim Biophys Acta (2012) 1.35
Thyroid hormone excess rather than thyrotropin deficiency induces osteoporosis in hyperthyroidism. Mol Endocrinol (2007) 1.33
A study of recurrence and death from papillary thyroid cancer with 27 years of median follow-up. Surgery (2013) 1.30
Mice deficient in MCT8 reveal a mechanism regulating thyroid hormone secretion. J Clin Invest (2010) 1.28
A lack of thyroid hormones rather than excess thyrotropin causes abnormal skeletal development in hypothyroidism. Mol Endocrinol (2007) 1.27
Importance of monocarboxylate transporter 8 for the blood-brain barrier-dependent availability of 3,5,3'-triiodo-L-thyronine. Endocrinology (2009) 1.23
A thyroid hormone analog with reduced dependence on the monocarboxylate transporter 8 for tissue transport. Endocrinology (2009) 1.21
Type 3 deiodinase deficiency results in functional abnormalities at multiple levels of the thyroid axis. Endocrinology (2007) 1.21
Hypothyroidism in thyroid transcription factor 1 haploinsufficiency is caused by reduced expression of the thyroid-stimulating hormone receptor. Mol Endocrinol (2003) 1.19
Thyrocyte-specific inactivation of p53 and Pten results in anaplastic thyroid carcinomas faithfully recapitulating human tumors. Oncotarget (2011) 1.19
Missense mutations of dual oxidase 2 (DUOX2) implicated in congenital hypothyroidism have impaired trafficking in cells reconstituted with DUOX2 maturation factor. Mol Endocrinol (2007) 1.17
Thyroid hormone action in the absence of thyroid hormone receptor DNA-binding in vivo. J Clin Invest (2003) 1.16
Genetic causes of congenital hypothyroidism due to dyshormonogenesis. Curr Opin Pediatr (2011) 1.14
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International Union of Pharmacology. LIX. The pharmacology and classification of the nuclear receptor superfamily: thyroid hormone receptors. Pharmacol Rev (2006) 1.14
Thyroid hormone-regulated mouse cerebral cortex genes are differentially dependent on the source of the hormone: a study in monocarboxylate transporter-8- and deiodinase-2-deficient mice. Endocrinology (2010) 1.13
Effects of ligand and thyroid hormone receptor isoforms on hepatic gene expression profiles of thyroid hormone receptor knockout mice. EMBO Rep (2003) 1.12
The nuclear receptor corepressor (NCoR) controls thyroid hormone sensitivity and the set point of the hypothalamic-pituitary-thyroid axis. Mol Endocrinol (2011) 1.10
Cytosolic action of thyroid hormone leads to induction of hypoxia-inducible factor-1alpha and glycolytic genes. Mol Endocrinol (2005) 1.10
Thyroid hormone responsive genes in cultured human fibroblasts. J Clin Endocrinol Metab (2004) 1.09
Changes in thyroid status during perinatal development of MCT8-deficient male mice. Endocrinology (2013) 1.09
X-linked paroxysmal dyskinesia and severe global retardation caused by defective MCT8 gene. J Neurol (2005) 1.08
Regression of a large goiter in a patient with resistance to thyroid hormone by every other day treatment with triiodothyronine. Thyroid (2004) 1.07
The interaction between nuclear receptor corepressor and histone deacetylase 3 regulates both positive and negative thyroid hormone action in vivo. Mol Endocrinol (2010) 1.05
White matter abnormalities and dystonic motor disorder associated with mutations in the SLC16A2 gene. Dev Med Child Neurol (2009) 1.05
QT dispersion and diastolic functions in differential diagnosis of primary mitral valve prolapse and rheumatic mitral valve prolapse. Pediatr Cardiol (2007) 1.05
Negative regulation by thyroid hormone receptor requires an intact coactivator-binding surface. J Clin Invest (2005) 1.05
Distinct roles of deiodinases on the phenotype of Mct8 defect: a comparison of eight different mouse genotypes. Endocrinology (2011) 1.03
Thyroid transcription factor 1 rescues PAX8/p300 synergism impaired by a natural PAX8 paired domain mutation with dominant negative activity. Mol Endocrinol (2005) 1.03
Delineation of the discontinuous-conformational epitope of a monoclonal antibody displaying full in vitro and in vivo thyrotropin activity. Mol Endocrinol (2004) 1.02
A novel thyroid hormone receptor-beta mutation that fails to bind nuclear receptor corepressor in a patient as an apparent cause of severe, predominantly pituitary resistance to thyroid hormone. J Clin Endocrinol Metab (2006) 1.02
Autoimmunity in patients with resistance to thyroid hormone. J Clin Endocrinol Metab (2010) 1.00
A familial thyrotropin (TSH) receptor mutation provides in vivo evidence that the inositol phosphates/Ca2+ cascade mediates TSH action on thyroid hormone synthesis. J Clin Endocrinol Metab (2007) 0.99
Evaluation of postpartum carbohydrate intolerance and cardiovascular risk factors in women with gestational diabetes. Gynecol Endocrinol (2010) 0.99
Temperature homeostasis in transgenic mice lacking thyroid hormone receptor-alpha gene products. Endocrinology (2005) 0.99
A single copy of the recently identified dual oxidase maturation factor (DUOXA) 1 gene produces only mild transient hypothyroidism in a patient with a novel biallelic DUOXA2 mutation and monoallelic DUOXA1 deletion. J Clin Endocrinol Metab (2011) 0.99