Published in Oncogene on July 03, 2006
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Mig-6 controls EGFR trafficking and suppresses gliomagenesis. Proc Natl Acad Sci U S A (2010) 1.38
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Mig-6 modulates uterine steroid hormone responsiveness and exhibits altered expression in endometrial disease. Proc Natl Acad Sci U S A (2009) 1.28
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Mitogen-inducible gene 6 triggers apoptosis and exacerbates ER stress-induced β-cell death. Mol Endocrinol (2012) 0.92
Cartilage-specific deletion of Mig-6 results in osteoarthritis-like disorder with excessive articular chondrocyte proliferation. Proc Natl Acad Sci U S A (2014) 0.91
Perifosine induces differentiation and cell death in prostate cancer cells. Cancer Lett (2008) 0.90
Mig-6 is required for appropriate lung development and to ensure normal adult lung homeostasis. Development (2009) 0.90
Overexpression and knockout of miR-126 both promote leukemogenesis. Blood (2015) 0.88
Disturbed cartilage and joint homeostasis resulting from a loss of mitogen-inducible gene 6 in a mouse model of joint dysfunction. Arthritis Rheumatol (2014) 0.86
ERBB receptor feedback inhibitor 1 regulation of estrogen receptor activity is critical for uterine implantation in mice. Biol Reprod (2009) 0.85
Mig-6 plays a critical role in the regulation of cholesterol homeostasis and bile acid synthesis. PLoS One (2012) 0.82
Structure and mechanism of activity-based inhibition of the EGF receptor by Mig6. Nat Struct Mol Biol (2015) 0.82
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Whole genome sequencing of glioblastoma multiforme identifies multiple structural variations involved in EGFR activation. Mutagenesis (2014) 0.81
Chk1 phosphorylates the tumour suppressor Mig-6, regulating the activation of EGF signalling. EMBO J (2012) 0.81
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GADD45gamma: a new vitamin D-regulated gene that is antiproliferative in prostate cancer cells. Endocrinology (2010) 0.80
Glucocorticoid-induced suppression of β-cell proliferation is mediated by Mig6. Endocrinology (2013) 0.80
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Thyroid-specific knockout of the tumor suppressor mitogen-inducible gene 6 activates epidermal growth factor receptor signaling pathways and suppresses nuclear factor-κB activity. Surgery (2011) 0.79
Mig-6 regulates endometrial genes involved in cell cycle and progesterone signaling. Biochem Biophys Res Commun (2015) 0.79
Mig-6 suppresses endometrial cancer associated with Pten deficiency and ERK activation. Cancer Res (2014) 0.79
Gene 33/Mig6 inhibits hexavalent chromium-induced DNA damage and cell transformation in human lung epithelial cells. Oncotarget (2016) 0.78
The induction of MIG6 under hypoxic conditions is critical for dormancy in primary cultured lung cancer cells with activating EGFR mutations. Oncogene (2016) 0.78
The role of small adaptor proteins in the control of oncogenic signalingr driven by tyrosine kinases in human cancer. Oncotarget (2016) 0.77
A pervasive role for MIG6 in restraining cell proliferation. Cell Death Differ (2013) 0.77
The antitumorigenic function of EGFR in metastatic breast cancer is regulated by expression of Mig6. Neoplasia (2015) 0.76
Mitogen-Inducible Gene-6 Mediates Feedback Inhibition from Mutated BRAF towards the Epidermal Growth Factor Receptor and Thereby Limits Malignant Transformation. PLoS One (2015) 0.76
Mig-6 gene knockout induces neointimal hyperplasia in the vascular smooth muscle cell. Dis Markers (2014) 0.75
Decreased Mitogen Inducible Gene 6 (MIG-6) Associated with Symptom Severity in Children with Autism. Biomark Insights (2014) 0.75
Understanding the molecular basis of EGFR kinase domain/MIG-6 peptide recognition complex using computational analyses. BMC Bioinformatics (2015) 0.75
Fatty Liver and Insulin Resistance in the Liver-Specific Knockout Mice of Mitogen Inducible Gene-6. J Diabetes Res (2016) 0.75
Upregulation of mitogen-inducible gene 6 triggers antitumor effect and attenuates progesterone resistance in endometrial carcinoma cells. Cancer Gene Ther (2015) 0.75
Inhibition of Cdc42 is essential for Mig-6 suppression of cell migration induced by EGF. Oncotarget (2016) 0.75
Nuclear Gene 33/Mig6 Regulates the DNA Damage Response through an ATM-dependent Mechanism. J Biol Chem (2017) 0.75
Single-cell RNA sequencing reveals an altered gene expression pattern as a result of CRISPR/cas9-mediated deletion of Gene 33/Mig6 and chronic exposure to hexavalent chromium in human lung epithelial cells. Toxicol Appl Pharmacol (2017) 0.75
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