p53 mutation in hepatocellular carcinoma after aflatoxin exposure.

PubWeight™: 1.81‹?› | Rank: Top 3%

🔗 View Article (PMID 1682737)

Published in Lancet on November 30, 1991

Authors

M Ozturk1

Author Affiliations

1: Massachusetts General Hospital Cancer Center.

Articles citing this

The global epidemiology of hepatocellular carcinoma: present and future. Clin Liver Dis (2011) 2.96

Genetics of hepatocellular carcinoma. World J Gastroenterol (2007) 1.64

Mutational signatures: the patterns of somatic mutations hidden in cancer genomes. Curr Opin Genet Dev (2013) 1.62

UV and skin cancer: specific p53 gene mutation in normal skin as a biologically relevant exposure measurement. Proc Natl Acad Sci U S A (1994) 1.50

Susceptibility to hepatocellular carcinoma is associated with genetic variation in the enzymatic detoxification of aflatoxin B1. Proc Natl Acad Sci U S A (1995) 1.41

Classification of hepatocellular carcinoma according to hepatocellular and biliary differentiation markers. Clinical and biological implications. Am J Pathol (1996) 1.35

Immunohistochemical study on p53, H-rasp21, c-erbB-2 protein and PCNA expression in HCC tissues of Han and minority ethnic patients. World J Gastroenterol (2000) 1.29

Genetic heterogeneity of hepatocellular carcinoma. Proc Natl Acad Sci U S A (1994) 1.28

Association of TP53 mutations with stem cell-like gene expression and survival of patients with hepatocellular carcinoma. Gastroenterology (2010) 1.28

Molecular genetics of hepatocellular neoplasia. Am J Transl Res (2010) 1.16

The genetic and epigenetic alterations in human hepatocellular carcinoma: a recent update. Protein Cell (2014) 1.10

The mutagenic potential of duodenoesophageal reflux. Ann Surg (2005) 1.08

Aflatoxin B1-induced hepatocellular carcinoma in developing countries: Geographical distribution, mechanism of action and prevention. Oncol Lett (2013) 1.08

Aspergillus oxylipin signaling and quorum sensing pathways depend on g protein-coupled receptors. Toxins (Basel) (2012) 1.06

Comprehensive assessment of cancer missense mutation clustering in protein structures. Proc Natl Acad Sci U S A (2015) 1.06

Current understanding on aflatoxin biosynthesis and future perspective in reducing aflatoxin contamination. Toxins (Basel) (2012) 1.05

The clonal origin and clonal evolution of epithelial tumours. Int J Exp Pathol (2000) 1.04

Aflatoxin sufferer and p53 gene mutation in hepatocellular carcinoma. World J Gastroenterol (1998) 1.03

Database and software for the analysis of mutations at the human p53 gene. Nucleic Acids Res (1994) 1.03

Mutation signatures of carcinogen exposure: genome-wide detection and new opportunities for cancer prevention. Genome Med (2014) 0.89

Detoxification of Aflatoxin-Contaminated Maize by Neutral Electrolyzed Oxidizing Water. Toxins (Basel) (2015) 0.88

249 TP53 mutation has high prevalence and is correlated with larger and poorly differentiated HCC in Brazilian patients. BMC Cancer (2009) 0.88

Experimental evidence for mutagenic potential of duodenogastric juice on Barrett's esophagus. World J Surg (2003) 0.87

Expression of mutant p53 protein in hepatocellular carcinoma. Gut (1994) 0.86

Risk factors for hepatocellular carcinoma in India. J Clin Exp Hepatol (2014) 0.85

Involvement of DNA damage response pathways in hepatocellular carcinoma. Biomed Res Int (2014) 0.84

Selective induction of apoptosis in Hep 3B cells by topoisomerase I inhibitors: evidence for a protease-dependent pathway that does not activate cysteine protease P32. J Clin Invest (1996) 0.83

SIP1 is downregulated in hepatocellular carcinoma by promoter hypermethylation. BMC Cancer (2011) 0.82

Critical roles of p53 in epithelial-mesenchymal transition and metastasis of hepatocellular carcinoma cells. PLoS One (2013) 0.81

Association among polymorphisms in EGFR gene exons, lifestyle and risk of gastric cancer with gender differences in Chinese Han subjects. PLoS One (2013) 0.81

Target genes discovery through copy number alteration analysis in human hepatocellular carcinoma. World J Gastroenterol (2013) 0.81

Identification of drivers from cancer genome diversity in hepatocellular carcinoma. Int J Mol Sci (2014) 0.81

Hepatocellular carcinoma p53 G > T transversions at codon 249: the fingerprint of aflatoxin exposure? Environ Health Perspect (1997) 0.80

Molecular dosimetry of aflatoxin exposure: contribution to understanding the multifactorial etiopathogenesis of primary hepatocellular carcinoma with particular reference to hepatitis B virus. Environ Health Perspect (1993) 0.79

Molecular pathogenesis of hepatocellular carcinoma and impact of therapeutic advances. F1000Res (2016) 0.78

Hepatocellular carcinoma and the underlying mechanisms. Afr Health Sci (2010) 0.78

Aflatoxins and fumonisins contamination of home-made food (weanimix) from cereal-legume blends for children. Ghana Med J (2014) 0.78

Codon 249 mutation of the p53 gene is a rare event in hepatocellular carcinomas from ethnic Chinese in Singapore. Br J Cancer (1995) 0.78

Mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression. Carcinogenesis (2015) 0.77

Detection of mutant p53 in hepatocellular cancer from Turkey and its correlation with clinicopathologic parameters. Dig Dis Sci (2003) 0.77

p53 expression in hepatocellular carcinoma in a population in Singapore with endemic hepatitis B virus infection. J Clin Pathol (1995) 0.76

Mutation inactivation of Nijmegen breakage syndrome gene (NBS1) in hepatocellular carcinoma and intrahepatic cholangiocarcinoma. PLoS One (2013) 0.76

Separate origins of hepatitis B virus surface antigen-negative foci and hepatocellular carcinomas in transgenic HBsAg (alb/psx) mice. Am J Pathol (2006) 0.76

Liver disease. Postgrad Med J (1994) 0.76

Current evidence for the hepatoprotective activities of the medicinal mushroom Antrodia cinnamomea. Chin Med (2013) 0.76

Endomyocardial fibrosis and hepatocellular carcinoma in Inhambane Province in Mozambique. Can J Cardiol (2007) 0.75

Duck hepatitis B virus infection, aflatoxin B1 and liver cancer in domestic Chinese ducks. Br J Cancer (1994) 0.75

The Molecular Basis of Toxins' Interactions with Intracellular Signaling via Discrete Portals. Toxins (Basel) (2017) 0.75