The 3' CCACCA sequence of tRNAAla(UGC) is the motif that is important in inducing Th1-like immune response, and this motif can be recognized by Toll-like receptor 3.

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Published in Clin Vaccine Immunol on July 01, 2006

Authors

Zhijun Wang1, Li Xiang, Junjie Shao, Zhenghong Yuan

Author Affiliations

1: Key Laboratory of Medical Molecular Virology, Shanghai Medical College, Fudan University, 200032, Shanghai, People's Republic of China. zjwang@shmu.edu.cn

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