Published in Ann N Y Acad Sci on April 01, 2006
The WWOX tumor suppressor is essential for postnatal survival and normal bone metabolism. J Biol Chem (2008) 1.67
Follicle-stimulating hormone stimulates TNF production from immune cells to enhance osteoblast and osteoclast formation. Proc Natl Acad Sci U S A (2006) 1.64
Intermittent recombinant TSH injections prevent ovariectomy-induced bone loss. Proc Natl Acad Sci U S A (2008) 1.46
Cocaine and amphetamine-regulated transcript may regulate bone remodeling as a circulating molecule. Endocrinology (2008) 0.92
FSH and TSH in the regulation of bone mass: the pituitary/immune/bone axis. Clin Dev Immunol (2013) 0.92
Metabolic and clinical consequences of hyperthyroidism on bone density. Int J Endocrinol (2013) 0.87
Newly reported roles of thyroid-stimulating hormone and follicle-stimulating hormone in bone remodelling. Int Orthop (2007) 0.86
Can bone loss be reversed by antithyroid drug therapy in premenopausal women with Graves' disease? Nutr Metab (Lond) (2010) 0.81
Energy expenditure and bone formation share a common sensitivity to AP-1 transcription in the hypothalamus. J Bone Miner Res (2012) 0.80
Thyrotropin serum levels are differentially associated with biochemical markers of bone turnover and stiffness in women and men: results from the SHIP cohorts. Osteoporos Int (2015) 0.78
Thyroid hormone receptors control developmental maturation of the middle ear and the size of the ossicular bones. Endocrinology (2012) 0.78
Low BMI and low TSH value as risk factors related to lower bone mineral density in postmenospausal women under levothyroxine therapy for differentiated thyroid carcinoma. Thyroid Res (2015) 0.77
PROXIMAL FEMORAL EPIPHYSIOLYSIS AND SUBCLINICAL HYPOTHYROIDISM: CASE REPORT. Rev Bras Ortop (2015) 0.75
Expanding the Role of Thyroid-Stimulating Hormone in Skeletal Physiology. Front Endocrinol (Lausanne) (2017) 0.75
FSH directly regulates bone mass. Cell (2006) 4.64
TSH is a negative regulator of skeletal remodeling. Cell (2003) 4.34
Searching for the autoimmune thyroid disease susceptibility genes: from gene mapping to gene function. Endocr Rev (2003) 1.85
Thyrotrophin receptor signaling dependence of Braf-induced thyroid tumor initiation in mice. Proc Natl Acad Sci U S A (2011) 1.82
The thyroid and pregnancy: a novel risk factor for very preterm delivery. Thyroid (2005) 1.82
Hyperthyroid-associated osteoporosis is exacerbated by the loss of TSH signaling. J Clin Invest (2012) 1.77
Mitochondria to nucleus stress signaling: a distinctive mechanism of NFkappaB/Rel activation through calcineurin-mediated inactivation of IkappaBbeta. J Cell Biol (2003) 1.69
Thyroid-stimulating hormone induces a Wnt-dependent, feed-forward loop for osteoblastogenesis in embryonic stem cell cultures. Proc Natl Acad Sci U S A (2011) 1.67
Epidermal growth factor as a candidate for ex vivo expansion of bone marrow-derived mesenchymal stem cells. Stem Cells (2005) 1.66
Follicle-stimulating hormone stimulates TNF production from immune cells to enhance osteoblast and osteoclast formation. Proc Natl Acad Sci U S A (2006) 1.64
Impaired osteoblastic differentiation, reduced bone formation, and severe osteoporosis in noggin-overexpressing mice. J Clin Invest (2003) 1.63
Glucocerebrosidase gene-deficient mouse recapitulates Gaucher disease displaying cellular and molecular dysregulation beyond the macrophage. Proc Natl Acad Sci U S A (2010) 1.60
Common and unique susceptibility loci in Graves and Hashimoto diseases: results of whole-genome screening in a data set of 102 multiplex families. Am J Hum Genet (2003) 1.59
Loss of MMP-2 disrupts skeletal and craniofacial development and results in decreased bone mineralization, joint erosion and defects in osteoblast and osteoclast growth. Hum Mol Genet (2007) 1.56
Smoke carcinogens cause bone loss through the aryl hydrocarbon receptor and induction of Cyp1 enzymes. Proc Natl Acad Sci U S A (2013) 1.54
Na+/H+ exchanger regulatory factor 1 (NHERF1) directly regulates osteogenesis. J Biol Chem (2012) 1.52
Molecular regulation of mechanotransduction. Biochem Biophys Res Commun (2005) 1.51
Intermittent recombinant TSH injections prevent ovariectomy-induced bone loss. Proc Natl Acad Sci U S A (2008) 1.46
A comparison of short-term changes in health-related quality of life in thyroid carcinoma patients undergoing diagnostic evaluation with recombinant human thyrotropin compared with thyroid hormone withdrawal. J Clin Endocrinol Metab (2006) 1.45
Oxytocin is an anabolic bone hormone. Proc Natl Acad Sci U S A (2009) 1.44
Ord-Hashimoto's disease: renaming a common disorder--again. Thyroid (2003) 1.41
Characterization of thyrotropin receptor antibody-induced signaling cascades. Endocrinology (2008) 1.37
Osteoclast signalling pathways. Biochem Biophys Res Commun (2005) 1.36
Directed differentiation of mouse embryonic stem cells into thyroid follicular cells. Endocrinology (2006) 1.35
Interferon-inducible protein 9 (CXCL11)-induced cell motility in keratinocytes requires calcium flux-dependent activation of mu-calpain. Mol Cell Biol (2005) 1.35
Genotype-phenotype correlation in 1,507 families with congenital adrenal hyperplasia owing to 21-hydroxylase deficiency. Proc Natl Acad Sci U S A (2013) 1.31
DNA damage drives accelerated bone aging via an NF-κB-dependent mechanism. J Bone Miner Res (2013) 1.31
BMP-12 treatment of adult mesenchymal stem cells in vitro augments tendon-like tissue formation and defect repair in vivo. PLoS One (2011) 1.29
Structure-phenotype correlations of human CYP21A2 mutations in congenital adrenal hyperplasia. Proc Natl Acad Sci U S A (2013) 1.28
TNFalpha mediates the skeletal effects of thyroid-stimulating hormone. Proc Natl Acad Sci U S A (2006) 1.27
Activating autoantibodies to the beta-1 adrenergic and m2 muscarinic receptors facilitate atrial fibrillation in patients with Graves' hyperthyroidism. J Am Coll Cardiol (2009) 1.26
ACTH protects against glucocorticoid-induced osteonecrosis of bone. Proc Natl Acad Sci U S A (2010) 1.26
PINCH-1 regulates the ERK-Bim pathway and contributes to apoptosis resistance in cancer cells. J Biol Chem (2007) 1.26
Parathyroid hormone receptor directly interacts with dishevelled to regulate beta-Catenin signaling and osteoclastogenesis. J Biol Chem (2010) 1.25
Committing embryonic stem cells to differentiate into thyrocyte-like cells in vitro. Endocrinology (2003) 1.25
A monoclonal thyroid-stimulating antibody. J Clin Invest (2002) 1.22
Efficacy and tolerability of intravenous ibandronate injections in postmenopausal osteoporosis: 2-year results from the DIVA study. J Rheumatol (2008) 1.18
Dissecting genetic heterogeneity in autoimmune thyroid diseases by subset analysis. J Autoimmun (2007) 1.18
Regulation of bone remodeling by vasopressin explains the bone loss in hyponatremia. Proc Natl Acad Sci U S A (2013) 1.17
Thyroglobulin is a thyroid specific gene for the familial autoimmune thyroid diseases. J Clin Endocrinol Metab (2002) 1.17
Calcineurin regulates bone formation by the osteoblast. Proc Natl Acad Sci U S A (2005) 1.16
Ligand-dependent inhibition of oligomerization at the human thyrotropin receptor. J Biol Chem (2002) 1.16
Possible interaction between HLA-DRbeta1 and thyroglobulin variants in Graves' disease. Thyroid (2006) 1.15
Estrogen inhibits RANKL-stimulated osteoclastic differentiation of human monocytes through estrogen and RANKL-regulated interaction of estrogen receptor-alpha with BCAR1 and Traf6. Exp Cell Res (2009) 1.15
Thyrotropin-independent induction of thyroid endoderm from embryonic stem cells by activin A. Endocrinology (2008) 1.14
FSH-receptor isoforms and FSH-dependent gene transcription in human monocytes and osteoclasts. Biochem Biophys Res Commun (2010) 1.12
Mechanisms balancing skeletal matrix synthesis and degradation. Biochem J (2002) 1.12
Expression and function of TNF-family proteins and receptors in human osteoblasts. Bone (2003) 1.12
Physiological loading of joints prevents cartilage degradation through CITED2. FASEB J (2010) 1.12
American Thyroid Association statement on optimal surgical management of goiter. Thyroid (2014) 1.11
Induction of a program gene expression during osteoblast differentiation with strontium ranelate. Biochem Biophys Res Commun (2007) 1.11
Follistatin-like protein 1 is a mesenchyme-derived inflammatory protein and may represent a biomarker for systemic-onset juvenile rheumatoid arthritis. Arthritis Rheum (2010) 1.10
Noninvasive prenatal diagnosis of congenital adrenal hyperplasia using cell-free fetal DNA in maternal plasma. J Clin Endocrinol Metab (2014) 1.09
The thyroid-stimulating hormone receptor: impact of thyroid-stimulating hormone and thyroid-stimulating hormone receptor antibodies on multimerization, cleavage, and signaling. Endocrinol Metab Clin North Am (2009) 1.08
Adenosine A(1) receptors regulate bone resorption in mice: adenosine A(1) receptor blockade or deletion increases bone density and prevents ovariectomy-induced bone loss in adenosine A(1) receptor-knockout mice. Arthritis Rheum (2010) 1.08
TSH receptor autoantibodies. Autoimmun Rev (2009) 1.08
Osteoclasts are important for bone angiogenesis. Blood (2009) 1.08
Molecular amino acid signatures in the MHC class II peptide-binding pocket predispose to autoimmune thyroiditis in humans and in mice. Proc Natl Acad Sci U S A (2008) 1.08
Neutral antibodies to the TSH receptor are present in Graves' disease and regulate selective signaling cascades. Endocrinology (2010) 1.08
Matrix metalloproteinase-1 treatment of muscle fibrosis. Acta Biomater (2008) 1.07
The influence of human leucocyte antigen (HLA) genes on autoimmune thyroid disease (AITD): results of studies in HLA-DR3 positive AITD families. Clin Endocrinol (Oxf) (2002) 1.07
TNF regulates cellular NAD+ metabolism in primary macrophages. Biochem Biophys Res Commun (2006) 1.06
Alpha9beta1: a novel osteoclast integrin that regulates osteoclast formation and function. J Bone Miner Res (2006) 1.06
Autoimmune thyroid disease in pregnancy: a review. J Womens Health (Larchmt) (2009) 1.05
Bone marrow oxytocin mediates the anabolic action of estrogen on the skeleton. J Biol Chem (2012) 1.05
Gene disruption of the calcium channel Orai1 results in inhibition of osteoclast and osteoblast differentiation and impairs skeletal development. Lab Invest (2012) 1.04
Intrathyroidal fetal microchimerism in Graves' disease. J Clin Endocrinol Metab (2002) 1.04
Blocking antibody to the β-subunit of FSH prevents bone loss by inhibiting bone resorption and stimulating bone synthesis. Proc Natl Acad Sci U S A (2012) 1.04
A multilocus model of the genetic architecture of autoimmune thyroid disorder, with clinical implications. Am J Hum Genet (2008) 1.03
Retarded developmental expression and patterning of retinal cone opsins in hypothyroid mice. Endocrinology (2008) 1.03
Disordered osteoclast formation and function in a CD38 (ADP-ribosyl cyclase)-deficient mouse establishes an essential role for CD38 in bone resorption. FASEB J (2003) 1.03
Negative regulation of RANKL-induced osteoclastic differentiation in RAW264.7 Cells by estrogen and phytoestrogens. J Biol Chem (2005) 1.02
Calcium and bone disease. Biofactors (2011) 1.02
Osteoclastogenesis, bone resorption, and osteoclast-based therapeutics. J Bone Miner Res (2003) 1.02
Gaucher disease gene GBA functions in immune regulation. Proc Natl Acad Sci U S A (2012) 1.02
Tenascin cytotactin epidermal growth factor-like repeat binds epidermal growth factor receptor with low affinity. J Cell Physiol (2007) 1.02
Fine mapping of loci linked to autoimmune thyroid disease identifies novel susceptibility genes. J Clin Endocrinol Metab (2012) 1.01