Published in Biochem Biophys Res Commun on March 18, 2005
Morphine treatment accelerates sarcoma-induced bone pain, bone loss, and spontaneous fracture in a murine model of bone cancer. Pain (2007) 1.88
Bone regeneration and stem cells. J Cell Mol Med (2011) 1.41
TRAF6 ubiquitin ligase is essential for RANKL signaling and osteoclast differentiation. Biochem Biophys Res Commun (2007) 1.30
Inactivation of IL11 signaling causes craniosynostosis, delayed tooth eruption, and supernumerary teeth. Am J Hum Genet (2011) 1.17
Estrogen inhibits RANKL-stimulated osteoclastic differentiation of human monocytes through estrogen and RANKL-regulated interaction of estrogen receptor-alpha with BCAR1 and Traf6. Exp Cell Res (2009) 1.15
Green tea and bone metabolism. Nutr Res (2009) 1.12
Expression of bone resorption genes in osteoarthritis and in osteoporosis. J Bone Miner Metab (2007) 1.12
Gene disruption of the calcium channel Orai1 results in inhibition of osteoclast and osteoblast differentiation and impairs skeletal development. Lab Invest (2012) 1.04
Syk-dependent actin dynamics regulate endocytic trafficking and processing of antigens internalized through the B-cell receptor. Mol Biol Cell (2007) 1.02
Hedgehog signaling induced by breast cancer cells promotes osteoclastogenesis and osteolysis. J Biol Chem (2010) 1.01
Activation of adenosine A(2A) receptor reduces osteoclast formation via PKA- and ERK1/2-mediated suppression of NFκB nuclear translocation. Br J Pharmacol (2013) 1.00
TRPV-5 mediates a receptor activator of NF-kappaB (RANK) ligand-induced increase in cytosolic Ca2+ in human osteoclasts and down-regulates bone resorption. J Biol Chem (2010) 0.96
RANKL, osteopontin, and osteoclast homeostasis in a hyperocclusion mouse model. Eur J Oral Sci (2008) 0.94
The hedgehog pathway conditions the bone microenvironment for osteolytic metastasis of breast cancer. Int J Breast Cancer (2011) 0.91
Inhibition of Rgs10 Expression Prevents Immune Cell Infiltration in Bacteria-induced Inflammatory Lesions and Osteoclast-mediated Bone Destruction. Bone Res (2013) 0.90
Bioceramics composition modulate resorption of human osteoclasts. J Mater Sci Mater Med (2005) 0.88
(-)-Epigallocatechin gallate reduces platelet-derived growth factor-BB-stimulated interleukin-6 synthesis in osteoblasts: suppression of SAPK/JNK. Mediators Inflamm (2009) 0.88
Activation of EPAC1/2 is essential for osteoclast formation by modulating NFκB nuclear translocation and actin cytoskeleton rearrangements. FASEB J (2014) 0.88
Gene expression responses in male fathead minnows exposed to binary mixtures of an estrogen and antiestrogen. BMC Genomics (2009) 0.86
Ameloblastin modulates osteoclastogenesis through the integrin/ERK pathway. Bone (2013) 0.84
Correlating RANK ligand/RANK binding kinetics with osteoclast formation and function. J Cell Biochem (2015) 0.83
Src mediates the mechanical activation of myogenesis by activating TNFα-converting enzyme. J Cell Sci (2013) 0.83
Understanding resolvin signaling pathways to improve oral health. Int J Mol Sci (2013) 0.82
Role of protein-tyrosine phosphatases in regulation of osteoclastic activity. Cell Mol Life Sci (2009) 0.82
An inducible, ligand-independent receptor activator of NF-κB gene to control osteoclast differentiation from monocytic precursors. PLoS One (2013) 0.82
Macrophage migration inhibitory factor is essential for osteoclastogenic mechanisms in vitro and in vivo mouse model of arthritis. Cytokine (2015) 0.81
Selective Regulation of MAPK Signaling Mediates RANKL-dependent Osteoclast Differentiation. Int J Biol Sci (2016) 0.78
Involvement of the Ca²⁺ signaling pathway in osteoprotegerin inhibition of osteoclast differentiation and maturation. J Vet Sci (2014) 0.78
Negative autoregulation of RANKL and c-Src signaling in osteoclasts. J Bone Miner Metab (2007) 0.77
Thiazolidinediones and bone. Clin Cases Miner Bone Metab (2007) 0.77
Single nucleotide polymorphisms in bone turnover-related genes in Koreans: ethnic differences in linkage disequilibrium and haplotype. BMC Med Genet (2007) 0.77
Comparison of Signaling Pathways Gene Expression in CD34(-) Umbilical Cord Blood and Bone Marrow Stem Cells. Stem Cells Int (2015) 0.76
Genetic studies of bone diseases: evidence for involvement of DNA damage response proteins in bone remodeling. Int J Biomed Sci (2007) 0.75
Three-Dimensional Mechanical Loading Modulates the Osteogenic Response of Mesenchymal Stem Cells to Tumor-Derived Soluble Signals. Tissue Eng Part A (2016) 0.75
Adenovirus-mediated siRNA targeting TNF-α and overexpression of bone morphogenetic protein-2 promotes early osteoblast differentiation on a cell model of Ti particle-induced inflammatory response in vitro. Braz J Med Biol Res (2013) 0.75
Combination of IL-6 and sIL-6R differentially regulate varying levels of RANKL-induced osteoclastogenesis through NF-κB, ERK and JNK signaling pathways. Sci Rep (2017) 0.75
Barley Seedling Extracts Inhibit RANKL-Induced Differentiation, Fusion, and Maturation of Osteoclasts in the Early-to-Late Stages of Osteoclastogenesis. Evid Based Complement Alternat Med (2017) 0.75
The inhibitors of cyclin-dependent kinases and GSK-3β enhance osteoclastogenesis. Biochem Biophys Rep (2015) 0.75
FSH directly regulates bone mass. Cell (2006) 4.64
TSH is a negative regulator of skeletal remodeling. Cell (2003) 4.34
Hyperthyroid-associated osteoporosis is exacerbated by the loss of TSH signaling. J Clin Invest (2012) 1.77
Mitochondria to nucleus stress signaling: a distinctive mechanism of NFkappaB/Rel activation through calcineurin-mediated inactivation of IkappaBbeta. J Cell Biol (2003) 1.69
Thyroid-stimulating hormone induces a Wnt-dependent, feed-forward loop for osteoblastogenesis in embryonic stem cell cultures. Proc Natl Acad Sci U S A (2011) 1.67
Follicle-stimulating hormone stimulates TNF production from immune cells to enhance osteoblast and osteoclast formation. Proc Natl Acad Sci U S A (2006) 1.64
Impaired osteoblastic differentiation, reduced bone formation, and severe osteoporosis in noggin-overexpressing mice. J Clin Invest (2003) 1.63
Glucocerebrosidase gene-deficient mouse recapitulates Gaucher disease displaying cellular and molecular dysregulation beyond the macrophage. Proc Natl Acad Sci U S A (2010) 1.60
Loss of MMP-2 disrupts skeletal and craniofacial development and results in decreased bone mineralization, joint erosion and defects in osteoblast and osteoclast growth. Hum Mol Genet (2007) 1.56
Smoke carcinogens cause bone loss through the aryl hydrocarbon receptor and induction of Cyp1 enzymes. Proc Natl Acad Sci U S A (2013) 1.54
Molecular regulation of mechanotransduction. Biochem Biophys Res Commun (2005) 1.51
Intermittent recombinant TSH injections prevent ovariectomy-induced bone loss. Proc Natl Acad Sci U S A (2008) 1.46
Oxytocin is an anabolic bone hormone. Proc Natl Acad Sci U S A (2009) 1.44
Genotype-phenotype correlation in 1,507 families with congenital adrenal hyperplasia owing to 21-hydroxylase deficiency. Proc Natl Acad Sci U S A (2013) 1.31
BMP-12 treatment of adult mesenchymal stem cells in vitro augments tendon-like tissue formation and defect repair in vivo. PLoS One (2011) 1.29
Structure-phenotype correlations of human CYP21A2 mutations in congenital adrenal hyperplasia. Proc Natl Acad Sci U S A (2013) 1.28
TNFalpha mediates the skeletal effects of thyroid-stimulating hormone. Proc Natl Acad Sci U S A (2006) 1.27
ACTH protects against glucocorticoid-induced osteonecrosis of bone. Proc Natl Acad Sci U S A (2010) 1.26
Efficacy and tolerability of intravenous ibandronate injections in postmenopausal osteoporosis: 2-year results from the DIVA study. J Rheumatol (2008) 1.18
Regulation of bone remodeling by vasopressin explains the bone loss in hyponatremia. Proc Natl Acad Sci U S A (2013) 1.17
G-CSF-induced tyrosine phosphorylation of Gab2 is Lyn kinase dependent and associated with enhanced Akt and differentiative, not proliferative, responses. Blood (2003) 1.17
Calcineurin regulates bone formation by the osteoblast. Proc Natl Acad Sci U S A (2005) 1.16
Loss of DNA polymerase zeta enhances spontaneous tumorigenesis. Cancer Res (2010) 1.15
TSH and bone loss. Ann N Y Acad Sci (2006) 1.12
FSH-receptor isoforms and FSH-dependent gene transcription in human monocytes and osteoclasts. Biochem Biophys Res Commun (2010) 1.12
Mechanisms balancing skeletal matrix synthesis and degradation. Biochem J (2002) 1.12
Physiological loading of joints prevents cartilage degradation through CITED2. FASEB J (2010) 1.12
Induction of a program gene expression during osteoblast differentiation with strontium ranelate. Biochem Biophys Res Commun (2007) 1.11
Noninvasive prenatal diagnosis of congenital adrenal hyperplasia using cell-free fetal DNA in maternal plasma. J Clin Endocrinol Metab (2014) 1.09
The thyroid-stimulating hormone receptor: impact of thyroid-stimulating hormone and thyroid-stimulating hormone receptor antibodies on multimerization, cleavage, and signaling. Endocrinol Metab Clin North Am (2009) 1.08
Adenosine A(1) receptors regulate bone resorption in mice: adenosine A(1) receptor blockade or deletion increases bone density and prevents ovariectomy-induced bone loss in adenosine A(1) receptor-knockout mice. Arthritis Rheum (2010) 1.08
TNF regulates cellular NAD+ metabolism in primary macrophages. Biochem Biophys Res Commun (2006) 1.06
Bone marrow oxytocin mediates the anabolic action of estrogen on the skeleton. J Biol Chem (2012) 1.05
Blocking antibody to the β-subunit of FSH prevents bone loss by inhibiting bone resorption and stimulating bone synthesis. Proc Natl Acad Sci U S A (2012) 1.04
Disordered osteoclast formation and function in a CD38 (ADP-ribosyl cyclase)-deficient mouse establishes an essential role for CD38 in bone resorption. FASEB J (2003) 1.03
Calcium and bone disease. Biofactors (2011) 1.02
Negative regulation of RANKL-induced osteoclastic differentiation in RAW264.7 Cells by estrogen and phytoestrogens. J Biol Chem (2005) 1.02
Gaucher disease gene GBA functions in immune regulation. Proc Natl Acad Sci U S A (2012) 1.02
Osteoclastic differentiation and function regulated by old and new pathways. Rev Endocr Metab Disord (2006) 1.01
Dasatinib inhibits the growth of molecularly heterogeneous myeloid leukemias. Clin Cancer Res (2010) 1.01
TNF-induced gene expression oscillates in time. Biochem Biophys Res Commun (2008) 1.01
Functional grouping of osteoclast genes revealed through microarray analysis. Biochem Biophys Res Commun (2007) 1.00
Skeletal receptors for steroid-family regulating glycoprotein hormones: A multilevel, integrated physiological control system. Ann N Y Acad Sci (2011) 1.00
Oxytocin deficiency impairs maternal skeletal remodeling. Biochem Biophys Res Commun (2009) 1.00
ACTH is a novel regulator of bone mass. Ann N Y Acad Sci (2010) 0.99
Regulated production of the pituitary hormone oxytocin from murine and human osteoblasts. Biochem Biophys Res Commun (2011) 0.99
Mechanisms of action of adrenocorticotropic hormone and other melanocortins relevant to the clinical management of patients with multiple sclerosis. Mult Scler (2012) 0.99
NO-dependent osteoclast motility: reliance on cGMP-dependent protein kinase I and VASP. J Cell Sci (2005) 0.96
The influence of thyroid-stimulating hormone and thyroid-stimulating hormone receptor antibodies on osteoclastogenesis. Thyroid (2011) 0.95
Selective upregulation of the ADP-ribosyl cyclases CD38 and CD157 by TNF but not by RANK-L reveals differences in downstream signaling. Am J Physiol Renal Physiol (2006) 0.95
Role of mitochondrial reactive oxygen species in osteoclast differentiation. Ann N Y Acad Sci (2010) 0.95
Glucocerebrosidase 2 gene deletion rescues type 1 Gaucher disease. Proc Natl Acad Sci U S A (2014) 0.94
Translational musculoskeletal science: is sarcopenia the next clinical target after osteoporosis? Ann N Y Acad Sci (2011) 0.93
Evidence that calcineurin is required for the genesis of bone-resorbing osteoclasts. Am J Physiol Renal Physiol (2006) 0.92
Blocking FSH action attenuates osteoclastogenesis. Biochem Biophys Res Commun (2012) 0.91
Necessity of inositol (1,4,5)-trisphosphate receptor 1 and mu-calpain in NO-induced osteoclast motility. J Cell Sci (2007) 0.91
HIV and bone loss. Curr Osteoporos Rep (2010) 0.90
The developmental basis of skeletal cell differentiation and the molecular basis of major skeletal defects. Biol Rev Camb Philos Soc (2008) 0.89
Bone loss in thyroid disease: role of low TSH and high thyroid hormone. Ann N Y Acad Sci (2007) 0.89
G-CSF stimulates Jak2-dependent Gab2 phosphorylation leading to Erk1/2 activation and cell proliferation. Cell Signal (2008) 0.89
A novel mechanism for coupling cellular intermediary metabolism to cytosolic Ca2+ signaling via CD38/ADP-ribosyl cyclase, a putative intracellular NAD+ sensor. FASEB J (2002) 0.89
Ca(2+) influx through the osteoclastic plasma membrane ryanodine receptor. Am J Physiol Renal Physiol (2002) 0.88
Male osteoporosis: epidemiology and the pathogenesis of aging bones. Curr Osteoporos Rep (2011) 0.87
Osteopetrosis with micro-lacunar resorption because of defective integrin organization. Lab Invest (2009) 0.87
Kaposi sarcoma-associated herpesvirus-encoded viral FLICE inhibitory protein (vFLIP) K13 cooperates with Myc to promote lymphoma in mice. Cancer Biol Ther (2010) 0.87
Disorders associated with acute rapid and severe bone loss. J Bone Miner Res (2003) 0.87
Evaluating the antifracture efficacy of bisphosphonates. Rev Recent Clin Trials (2009) 0.87
The role of FSH and TSH in bone loss and its clinical relevance. Curr Osteoporos Rep (2010) 0.86
Translational medicine: Double protection for weakened bones. Nature (2012) 0.86
Vitamin C prevents hypogonadal bone loss. PLoS One (2012) 0.85
TNF-induced oscillations in combinatorial transcription factor binding. Biochem Biophys Res Commun (2008) 0.85
Commentary-FSH and bone 2010: evolving evidence. Eur J Endocrinol (2010) 0.85
Deletion of the RNA-editing enzyme ADAR1 causes regression of established chronic myelogenous leukemia in mice. Int J Cancer (2012) 0.84
The central nervous system (CNS)-independent anti-bone-resorptive activity of muscle contraction and the underlying molecular and cellular signatures. J Biol Chem (2013) 0.84
Identification of CITED2 as a negative regulator of fracture healing. Biochem Biophys Res Commun (2009) 0.84
Pediatric myelodysplastic syndromes: they do exist! J Pediatr Hematol Oncol (2014) 0.84
CD38 is required for priming by TNF-alpha: a mechanism for extracellular coordination of cell fate. Am J Physiol Renal Physiol (2006) 0.84
A diarylheptanoid phytoestrogen from Curcuma comosa, 1,7-diphenyl-4,6-heptadien-3-ol, accelerates human osteoblast proliferation and differentiation. Phytomedicine (2013) 0.83
Regulation of bone turnover by calcium-regulated calcium channels. Ann N Y Acad Sci (2010) 0.83
Bone, inflammation, and inflammatory bowel disease. Curr Osteoporos Rep (2011) 0.83
Functional osteoclast attachment requires inositol-1,4,5-trisphosphate receptor-associated cGMP-dependent kinase substrate. Lab Invest (2010) 0.82
Understanding estrogen action during menopause. Endocrinology (2009) 0.82
Regulation of FSH receptor promoter activation in the osteoclast. Biochem Biophys Res Commun (2007) 0.82
Genetic confirmation for a central role for TNFα in the direct action of thyroid stimulating hormone on the skeleton. Proc Natl Acad Sci U S A (2013) 0.82
Complexity in signal transduction. Ann N Y Acad Sci (2010) 0.82
Nandrolone slows hindlimb bone loss in a rat model of bone loss due to denervation. Ann N Y Acad Sci (2010) 0.82
Follicle stimulating hormone receptor in mesenchymal stem cells integrates effects of glycoprotein reproductive hormones. Ann N Y Acad Sci (2014) 0.82
Disease-drug pairs revealed by computational genomic connectivity mapping on GBA1 deficient, Gaucher disease mice. Biochem Biophys Res Commun (2012) 0.81
Cellular and molecular consequences of calcineurin A alpha gene deletion. Ann N Y Acad Sci (2007) 0.81
Intravenous injections of soluble drag-reducing polymers reduce foreign body reaction to implants. ASAIO J (2009) 0.81
Low TSH triggers bone loss: fact or fiction? Thyroid (2006) 0.81
Structure and functional regulation of the CD38 promoter. Biochem Biophys Res Commun (2006) 0.81
Bisphosphonates induce inflammation and rupture of atherosclerotic plaques in apolipoprotein-E null mice. Biochem Biophys Res Commun (2005) 0.81
Osteoporosis: trends and intervention. Mt Sinai J Med (2002) 0.80
Further evidence for direct pro-resorptive actions of FSH. Biochem Biophys Res Commun (2010) 0.80
Further evidence that FSH causes bone loss independently of low estrogen. Endocrine (2012) 0.80