Published in Circ Res on July 13, 2006
Interaction between alk1 and blood flow in the development of arteriovenous malformations. Development (2011) 1.42
TGFβ signaling and cardiovascular diseases. Int J Biol Sci (2012) 1.35
Novel biochemical pathways of endoglin in vascular cell physiology. J Cell Biochem (2007) 1.34
Generation of a floxed allele of the mouse Endoglin gene. Genesis (2007) 1.02
Increased plasma soluble endoglin levels as an indicator of cardiovascular alterations in hypertensive and diabetic patients. BMC Med (2010) 0.99
Endoglin regulates the activation and quiescence of endothelium by participating in canonical and non-canonical TGF-β signaling pathways. J Cell Sci (2013) 0.93
Overexpression of endoglin modulates TGF-β1-signalling pathways in a novel immortalized mouse hepatic stellate cell line. PLoS One (2013) 0.82
Endoglin: a critical mediator of cardiovascular health. Vasc Health Risk Manag (2013) 0.81
Endoglin regulates mural cell adhesion in the circulatory system. Cell Mol Life Sci (2015) 0.79
Heterozygous deficiency of endoglin decreases insulin and hepatic triglyceride levels during high fat diet. PLoS One (2013) 0.79
Impaired wound repair in adult endoglin heterozygous mice associated with lower NO bioavailability. J Invest Dermatol (2013) 0.79
Endoglin haploinsufficiency promotes fibroblast accumulation during wound healing through Akt activation. PLoS One (2013) 0.78
Endoglin in liver fibrogenesis: Bridging basic science and clinical practice. World J Biol Chem (2014) 0.78
Soluble endoglin contributes to the pathogenesis of preeclampsia. Nat Med (2006) 6.21
Metformin prevents experimental gentamicin-induced nephropathy by a mitochondria-dependent pathway. Kidney Int (2010) 3.08
TGF-β/TGF-β receptor system and its role in physiological and pathological conditions. Clin Sci (Lond) (2011) 1.90
Reduced angiogenic responses in adult Endoglin heterozygous mice. Cardiovasc Res (2006) 1.88
Vascular injury induces expression of periostin: implications for vascular cell differentiation and migration. Arterioscler Thromb Vasc Biol (2004) 1.76
SETBP1 overexpression is a novel leukemogenic mechanism that predicts adverse outcome in elderly patients with acute myeloid leukemia. Blood (2009) 1.76
A role for endoglin in coupling eNOS activity and regulating vascular tone revealed in hereditary hemorrhagic telangiectasia. Circ Res (2005) 1.76
Interaction and functional interplay between endoglin and ALK-1, two components of the endothelial transforming growth factor-beta receptor complex. J Cell Physiol (2005) 1.64
Pulmonary hypertension in adult Alk1 heterozygous mice due to oxidative stress. Cardiovasc Res (2011) 1.59
Extracellular and cytoplasmic domains of endoglin interact with the transforming growth factor-beta receptors I and II. J Biol Chem (2002) 1.49
Role of TGF-β in chronic kidney disease: an integration of tubular, glomerular and vascular effects. Cell Tissue Res (2011) 1.49
Endoglin null endothelial cells proliferate faster and are more responsive to transforming growth factor beta1 with higher affinity receptors and an activated Alk1 pathway. J Biol Chem (2005) 1.47
Endoglin regulates nitric oxide-dependent vasodilatation. FASEB J (2004) 1.47
Nocturia in Spanish patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia (LUTS/BPH). Curr Med Res Opin (2008) 1.44
The physiological role of endoglin in the cardiovascular system. Am J Physiol Heart Circ Physiol (2010) 1.44
Notch and transforming growth factor-beta (TGFbeta) signaling pathways cooperatively regulate vascular smooth muscle cell differentiation. J Biol Chem (2010) 1.38
Novel biochemical pathways of endoglin in vascular cell physiology. J Cell Biochem (2007) 1.34
Endoglin regulates cytoskeletal organization through binding to ZRP-1, a member of the Lim family of proteins. J Biol Chem (2004) 1.34
Endoglin structure and function: Determinants of endoglin phosphorylation by transforming growth factor-beta receptors. J Biol Chem (2006) 1.34
CD105 prevents apoptosis in hypoxic endothelial cells. J Cell Sci (2003) 1.30
BMP9 mutations cause a vascular-anomaly syndrome with phenotypic overlap with hereditary hemorrhagic telangiectasia. Am J Hum Genet (2013) 1.29
Vav3 proto-oncogene deficiency leads to sympathetic hyperactivity and cardiovascular dysfunction. Nat Med (2006) 1.27
Cerebral vascular abnormalities in a murine model of hereditary hemorrhagic telangiectasia. Stroke (2003) 1.25
ROS-NFkappaB mediates TGF-beta1-induced expression of urokinase-type plasminogen activator, matrix metalloproteinase-9 and cell invasion. Mol Cell Biochem (2010) 1.25
VE-cadherin is a critical endothelial regulator of TGF-beta signalling. EMBO J (2008) 1.22
Endoglin controls cell migration and composition of focal adhesions: function of the cytosolic domain. J Biol Chem (2004) 1.20
Structural model of human endoglin, a transmembrane receptor responsible for hereditary hemorrhagic telangiectasia. J Mol Biol (2006) 1.17
Reduced endoglin activity limits cardiac fibrosis and improves survival in heart failure. Circulation (2012) 1.12
Multivalent recombinant proteins for probing functions of leucocyte surface proteins such as the CD200 receptor. Immunology (2005) 1.10
Endothelial endoglin is involved in inflammation: role in leukocyte adhesion and transmigration. Blood (2012) 1.08
Caveolin-1 interacts and cooperates with the transforming growth factor-beta type I receptor ALK1 in endothelial caveolae. Cardiovasc Res (2007) 1.07
Reduced tumor growth and angiogenesis in endoglin-haploinsufficient mice. Tumour Biol (2006) 1.07
Novel mutations and polymorphisms in genes causing hereditary hemorrhagic telangiectasia. Hum Mutat (2005) 1.07
IQGAP1 suppresses TβRII-mediated myofibroblastic activation and metastatic growth in liver. J Clin Invest (2013) 1.06
L- and S-endoglin differentially modulate TGFbeta1 signaling mediated by ALK1 and ALK5 in L6E9 myoblasts. J Cell Sci (2008) 1.05
Endoglin suppresses human prostate cancer metastasis. Clin Exp Metastasis (2010) 1.04
Endoglin upregulation during experimental renal interstitial fibrosis in mice. Hypertension (2002) 1.04
Expression and characterization of recombinant osteopontin peptides representing matrix metalloproteinase proteolytic fragments. Matrix Biol (2004) 1.03
Endoglin increases eNOS expression by modulating Smad2 protein levels and Smad2-dependent TGF-beta signaling. J Cell Physiol (2007) 1.02
Structural and functional insights into endoglin ligand recognition and binding. PLoS One (2012) 1.02
Endoglin regulates cancer-stromal cell interactions in prostate tumors. Cancer Res (2011) 1.02
Matrix metalloproteinase 13 mediates nitric oxide activation of endothelial cell migration. Proc Natl Acad Sci U S A (2005) 1.02
Disease-associated mutations in conserved residues of ALK-1 kinase domain. Eur J Hum Genet (2003) 1.02
Endoglin is required for myogenic differentiation potential of neural crest stem cells. Dev Biol (2007) 1.02
BMP9 regulates endoglin-dependent chemokine responses in endothelial cells. Blood (2012) 1.01
Subcellular targets of cisplatin cytotoxicity: an integrated view. Pharmacol Ther (2012) 1.01
Increases in serum estrogen levels during major illness are caused by increased peripheral aromatization. Am J Physiol Endocrinol Metab (2006) 1.00
Functional blockade of Smad4 leads to a decrease in beta-catenin levels and signaling activity in human pancreatic carcinoma cells. Carcinogenesis (2008) 1.00
Mice deficient in telomerase activity develop hypertension because of an excess of endothelin production. Circulation (2006) 1.00
Quercetin reduces cisplatin nephrotoxicity in rats without compromising its anti-tumour activity. Nephrol Dial Transplant (2011) 0.99
Soluble endoglin modulates aberrant cerebral vascular remodeling. Ann Neurol (2009) 0.98
Endoglin plays distinct roles in vascular smooth muscle cell recruitment and regulation of arteriovenous identity during angiogenesis. Dev Dyn (2009) 0.98
Expression of endoglin in human mesangial cells: modulation of extracellular matrix synthesis. Biochim Biophys Acta (2002) 0.97
RhoA-mediated signaling in Notch-induced senescence-like growth arrest and endothelial barrier dysfunction. Arterioscler Thromb Vasc Biol (2011) 0.97
Deletion of H-Ras decreases renal fibrosis and myofibroblast activation following ureteral obstruction in mice. Kidney Int (2009) 0.97
Activation of Erk1/2 and Akt following unilateral ureteral obstruction. Kidney Int (2008) 0.96
Spontaneous adult-onset pulmonary arterial hypertension attributable to increased endothelial oxidative stress in a murine model of hereditary hemorrhagic telangiectasia. Arterioscler Thromb Vasc Biol (2009) 0.95
Mutation analysis in Spanish patients with hereditary hemorrhagic telangiectasia: deficient endoglin up-regulation in activated monocytes. Clin Chem (2004) 0.95
Characterization of 17 novel endoglin mutations associated with hereditary hemorrhagic telangiectasia. Hum Mutat (2003) 0.95
Expression of the TGF-beta coreceptor endoglin in epidermal keratinocytes and its dual role in multistage mouse skin carcinogenesis. Oncogene (2003) 0.95
A critical role for endoglin in the emergence of blood during embryonic development. Blood (2012) 0.95
Collagen, type V, alpha1 (COL5A1) is regulated by TGF-beta in osteoblasts. Matrix Biol (2004) 0.94
Gene expression fingerprinting for human hereditary hemorrhagic telangiectasia. Hum Mol Genet (2007) 0.93
Characterization of murine S-endoglin isoform and its effects on tumor development. Oncogene (2005) 0.93
Mutation study of Spanish patients with hereditary hemorrhagic telangiectasia and expression analysis of Endoglin and ALK1. Hum Mutat (2006) 0.93
CD105 inhibits transforming growth factor-beta-Smad3 signalling. Anticancer Res (2004) 0.93
S-endoglin expression is induced in senescent endothelial cells and contributes to vascular pathology. Circ Res (2008) 0.92
Long-term nebivolol administration reduces renal fibrosis and prevents endothelial dysfunction in rats with hypertension induced by renal mass reduction. J Hypertens (2007) 0.92
Endoglin expression regulates basal and TGF-beta1-induced extracellular matrix synthesis in cultured L6E9 myoblasts. Cell Physiol Biochem (2004) 0.91
Identification of serum endoglin as a novel prognostic marker after acute myocardial infarction. J Cell Mol Med (2008) 0.90
Endoglin-mediated suppression of prostate cancer invasion is regulated by activin and bone morphogenetic protein type II receptors. PLoS One (2013) 0.90
Coordinate gene expression patterns during osteoblast maturation and retinoic acid treatment of MC3T3-E1 cells. J Bone Miner Metab (2002) 0.89
Genistein induces phenotypic reversion of endoglin deficiency in human prostate cancer cells. Mol Pharmacol (2007) 0.89
Oxysterol-induced soluble endoglin release and its involvement in hypertension. Circulation (2012) 0.89
Identification of an invasion and tumor-suppressing gene, Endoglin (ENG), silenced by both epigenetic inactivation and allelic loss in esophageal squamous cell carcinoma. Int J Cancer (2008) 0.89
Relative roles of endothelin-1 and angiotensin II in experimental post-ischaemic acute renal failure. Nephrol Dial Transplant (2004) 0.89
Endoglin phosphorylation by ALK2 contributes to the regulation of prostate cancer cell migration. Carcinogenesis (2009) 0.89
Mutation study of Spanish patients with hereditary hemorrhagic telangiectasia. BMC Med Genet (2008) 0.89
5'UTR mutations of ENG cause hereditary hemorrhagic telangiectasia. Orphanet J Rare Dis (2011) 0.89