Published in J Biol Chem on May 17, 2004
Endoglin (CD105) up-regulation in pulmonary microvasculature of ventilated preterm infants. Am J Respir Crit Care Med (2008) 1.67
Novel biochemical pathways of endoglin in vascular cell physiology. J Cell Biochem (2007) 1.34
Endoglin promotes transforming growth factor beta-mediated Smad 1/5/8 signaling and inhibits endothelial cell migration through its association with GIPC. J Biol Chem (2008) 1.27
The mouse lymph node as an ectopic transplantation site for multiple tissues. Nat Biotechnol (2012) 1.27
Cell origin of human mesenchymal stem cells determines a different healing performance in cardiac regeneration. PLoS One (2011) 1.22
Relative percentage and zonal distribution of mesenchymal progenitor cells in human osteoarthritic and normal cartilage. Arthritis Res Ther (2011) 1.19
Hereditary hemorrhagic telangiectasia, a vascular dysplasia affecting the TGF-beta signaling pathway. Clin Med Res (2006) 1.17
CEACAM engagement by human pathogens enhances cell adhesion and counteracts bacteria-induced detachment of epithelial cells. J Cell Biol (2005) 1.17
Supervillin modulation of focal adhesions involving TRIP6/ZRP-1. J Cell Biol (2006) 1.11
ALK5 phosphorylation of the endoglin cytoplasmic domain regulates Smad1/5/8 signaling and endothelial cell migration. Carcinogenesis (2009) 1.02
Endoglin is required for myogenic differentiation potential of neural crest stem cells. Dev Biol (2007) 1.02
SPARC promotes pericyte recruitment via inhibition of endoglin-dependent TGF-β1 activity. J Cell Biol (2011) 1.02
CD105 (endoglin)-negative murine mesenchymal stromal cells define a new multipotent subpopulation with distinct differentiation and immunomodulatory capacities. PLoS One (2013) 1.00
Endoglin regulates PI3-kinase/Akt trafficking and signaling to alter endothelial capillary stability during angiogenesis. Mol Biol Cell (2012) 0.98
Casein kinase 2beta as a novel enhancer of activin-like receptor-1 signaling. FASEB J (2009) 0.92
Endoglin-mediated suppression of prostate cancer invasion is regulated by activin and bone morphogenetic protein type II receptors. PLoS One (2013) 0.90
TRIP6: an adaptor protein that regulates cell motility, antiapoptotic signaling and transcriptional activity. Cell Signal (2011) 0.89
Antibody-directed coupling of endoglin and MMP-14 is a key mechanism for endoglin shedding and deregulation of TGF-β signaling. Oncogene (2013) 0.89
Endoglin phosphorylation by ALK2 contributes to the regulation of prostate cancer cell migration. Carcinogenesis (2009) 0.89
PTPL1/FAP-1 negatively regulates TRIP6 function in lysophosphatidic acid-induced cell migration. J Biol Chem (2007) 0.88
Isolation and morphological characterisation of ovine adipose-derived mesenchymal stem cells in culture. Int J Stem Cells (2011) 0.84
Endoglin - a marker of vascular endothelial cell proliferation in cancer. Contemp Oncol (Pozn) (2012) 0.84
Effects of the combination of TRC105 and bevacizumab on endothelial cell biology. Invest New Drugs (2014) 0.82
Endoglin: a critical mediator of cardiovascular health. Vasc Health Risk Manag (2013) 0.81
Single cell-derived clones from human adipose stem cells present different immunomodulatory properties. Clin Exp Immunol (2014) 0.80
Investigation of endoglin wild-type and missense mutant protein heterodimerisation using fluorescence microscopy based IF, BiFC and FRET analyses. PLoS One (2014) 0.79
Endoglin haploinsufficiency promotes fibroblast accumulation during wound healing through Akt activation. PLoS One (2013) 0.78
Endoglin in liver fibrogenesis: Bridging basic science and clinical practice. World J Biol Chem (2014) 0.78
Endoglin inhibits ERK-induced c-Myc and cyclin D1 expression to impede endothelial cell proliferation. Biochem Biophys Res Commun (2012) 0.77
Quantitative proteomic analysis revealed N'-nitrosonornicotine-induced down-regulation of nonmuscle myosin II and reduced cell migration in cultured human skin fibroblast cells. J Proteome Res (2013) 0.77
Dynamics of circulating microparticles in chronic kidney disease and transplantation: Is it really reliable marker? World J Transplant (2015) 0.77
Novel protein interactions with endoglin and activin receptor-like kinase 1: potential role in vascular networks. Mol Cell Proteomics (2013) 0.77
Osteogenic stem cell selection for repair and regeneration. Bone Rep (2016) 0.75
BMP9 Crosstalk with the Hippo Pathway Regulates Endothelial Cell Matricellular and Chemokine Responses. PLoS One (2015) 0.75
ALK1 signaling in development and disease: new paradigms. Cell Mol Life Sci (2017) 0.75
Proenkephalin A gene products activate a new family of sensory neuron--specific GPCRs. Nat Neurosci (2002) 2.92
Activin A skews macrophage polarization by promoting a proinflammatory phenotype and inhibiting the acquisition of anti-inflammatory macrophage markers. Blood (2011) 1.98
Endoglin expression is regulated by transcriptional cooperation between the hypoxia and transforming growth factor-beta pathways. J Biol Chem (2002) 1.95
Reduced angiogenic responses in adult Endoglin heterozygous mice. Cardiovasc Res (2006) 1.88
Vascular injury induces expression of periostin: implications for vascular cell differentiation and migration. Arterioscler Thromb Vasc Biol (2004) 1.76
Blood outgrowth endothelial cells from Hereditary Haemorrhagic Telangiectasia patients reveal abnormalities compatible with vascular lesions. Cardiovasc Res (2005) 1.76
Propranolol as antiangiogenic candidate for the therapy of hereditary haemorrhagic telangiectasia. Thromb Haemost (2012) 1.67
Interaction and functional interplay between endoglin and ALK-1, two components of the endothelial transforming growth factor-beta receptor complex. J Cell Physiol (2005) 1.64
Endoglin regulates nitric oxide-dependent vasodilatation. FASEB J (2004) 1.47
PTEN associates with the vault particles in HeLa cells. J Biol Chem (2002) 1.45
Notch and transforming growth factor-beta (TGFbeta) signaling pathways cooperatively regulate vascular smooth muscle cell differentiation. J Biol Chem (2010) 1.38
Novel biochemical pathways of endoglin in vascular cell physiology. J Cell Biochem (2007) 1.34
A cross-talk between hypoxia and TGF-beta orchestrates erythropoietin gene regulation through SP1 and Smads. J Mol Biol (2004) 1.34
Endoglin structure and function: Determinants of endoglin phosphorylation by transforming growth factor-beta receptors. J Biol Chem (2006) 1.34
Structural insights into molecular function of the metastasis-associated phosphatase PRL-3. J Biol Chem (2004) 1.22
The role of the TGF-β coreceptor endoglin in cancer. ScientificWorldJournal (2010) 1.21
Endoglin controls cell migration and composition of focal adhesions: function of the cytosolic domain. J Biol Chem (2004) 1.20
Hereditary hemorrhagic telangiectasia, a vascular dysplasia affecting the TGF-beta signaling pathway. Clin Med Res (2006) 1.17
Involvement of the PI 3-kinase signaling pathway in progression of colon adenocarcinoma. Carcinogenesis (2003) 1.16
Solution structure of the PDZ2 domain from cytosolic human phosphatase hPTP1E complexed with a peptide reveals contribution of the beta2-beta3 loop to PDZ domain-ligand interactions. J Mol Biol (2002) 1.11
Reviewing the mechanism of action of thiopurine drugs: towards a new paradigm in clinical practice. Med Sci Monit (2004) 1.07
L- and S-endoglin differentially modulate TGFbeta1 signaling mediated by ALK1 and ALK5 in L6E9 myoblasts. J Cell Sci (2008) 1.05
Endoglin suppresses human prostate cancer metastasis. Clin Exp Metastasis (2010) 1.04
Expression and characterization of recombinant osteopontin peptides representing matrix metalloproteinase proteolytic fragments. Matrix Biol (2004) 1.03
Endoglin increases eNOS expression by modulating Smad2 protein levels and Smad2-dependent TGF-beta signaling. J Cell Physiol (2007) 1.02
Endoglin is required for myogenic differentiation potential of neural crest stem cells. Dev Biol (2007) 1.02
Endoglin regulates cancer-stromal cell interactions in prostate tumors. Cancer Res (2011) 1.02
BMP9 regulates endoglin-dependent chemokine responses in endothelial cells. Blood (2012) 1.01
Endoglin modulation of TGF-beta1-induced collagen synthesis is dependent on ERK1/2 MAPK activation. Cell Physiol Biochem (2006) 1.00
Increases in serum estrogen levels during major illness are caused by increased peripheral aromatization. Am J Physiol Endocrinol Metab (2006) 1.00
Functional blockade of Smad4 leads to a decrease in beta-catenin levels and signaling activity in human pancreatic carcinoma cells. Carcinogenesis (2008) 1.00
Endoglin plays distinct roles in vascular smooth muscle cell recruitment and regulation of arteriovenous identity during angiogenesis. Dev Dyn (2009) 0.98
RhoA-mediated signaling in Notch-induced senescence-like growth arrest and endothelial barrier dysfunction. Arterioscler Thromb Vasc Biol (2011) 0.97
Expression of the TGF-beta coreceptor endoglin in epidermal keratinocytes and its dual role in multistage mouse skin carcinogenesis. Oncogene (2003) 0.95
Collagen, type V, alpha1 (COL5A1) is regulated by TGF-beta in osteoblasts. Matrix Biol (2004) 0.94
Estrogen therapy for hereditary haemorrhagic telangiectasia (HHT): Effects of raloxifene, on Endoglin and ALK1 expression in endothelial cells. Thromb Haemost (2010) 0.94
Characterization of murine S-endoglin isoform and its effects on tumor development. Oncogene (2005) 0.93
Endoglin regulates cyclooxygenase-2 expression and activity. Circ Res (2006) 0.93
Endoglin expression regulates basal and TGF-beta1-induced extracellular matrix synthesis in cultured L6E9 myoblasts. Cell Physiol Biochem (2004) 0.91
A review on clinical management and pharmacological therapy on hereditary haemorrhagic telangiectasia (HHT). Curr Vasc Pharmacol (2010) 0.90
Endoglin-mediated suppression of prostate cancer invasion is regulated by activin and bone morphogenetic protein type II receptors. PLoS One (2013) 0.90
Coordinate gene expression patterns during osteoblast maturation and retinoic acid treatment of MC3T3-E1 cells. J Bone Miner Metab (2002) 0.89
Genistein induces phenotypic reversion of endoglin deficiency in human prostate cancer cells. Mol Pharmacol (2007) 0.89
A role for endoglin as a suppressor of malignancy during mouse skin carcinogenesis. Cancer Res (2007) 0.89
Endoglin phosphorylation by ALK2 contributes to the regulation of prostate cancer cell migration. Carcinogenesis (2009) 0.89
Mechanisms of TGF-β-induced differentiation in human vascular smooth muscle cells. J Vasc Res (2011) 0.88
The Splicing Factor SRSF1 as a Marker for Endothelial Senescence. Front Physiol (2012) 0.88
Interactions of ribosomal protein S1 with DsrA and rpoS mRNA. Biochem Biophys Res Commun (2006) 0.88
Sprouty4 regulates endothelial cell migration via modulating integrin β3 stability through c-Src. Angiogenesis (2013) 0.87
Solution structure of a two-repeat fragment of major vault protein. J Mol Biol (2005) 0.87
The TGF-beta co-receptor endoglin modulates the expression and transforming potential of H-Ras. Carcinogenesis (2010) 0.86
Therapeutic action of tranexamic acid in hereditary haemorrhagic telangiectasia (HHT): regulation of ALK-1/endoglin pathway in endothelial cells. Thromb Haemost (2007) 0.85
Phosphatidylserine colocalizes with epichromatin in interphase nuclei and mitotic chromosomes. Nucleus (2012) 0.84
Immunosuppressor FK506 increases endoglin and activin receptor-like kinase 1 expression and modulates transforming growth factor-β1 signaling in endothelial cells. Mol Pharmacol (2011) 0.83
Targeting gene expression to endothelium in transgenic animals: a comparison of the human ICAM-2, PECAM-1 and endoglin promoters. Xenotransplantation (2003) 0.82
MiR-205 is downregulated in hereditary hemorrhagic telangiectasia and impairs TGF-beta signaling pathways in endothelial cells. Angiogenesis (2013) 0.82
Targeting a marker of the tumour neovasculature using a novel anti-human CD105-immunotoxin containing the non-toxic type 2 ribosome-inactivating protein nigrin b. Cancer Lett (2007) 0.82
In vitro and in vivo effects of an anti-mouse endoglin (CD105)-immunotoxin on the early stages of mouse B16MEL4A5 melanoma tumours. Cancer Immunol Immunother (2012) 0.81
TGF-{beta} signaling of human T cells is modulated by the ancillary TGF-{beta} receptor endoglin. Int Immunol (2005) 0.80
1H, 13C and 15N resonance assignments of the human phosphatase PRL-3. J Biomol NMR (2002) 0.80
A mammalian genetic system to screen for small molecules capable of disrupting protein-protein interactions. Anal Chem (2004) 0.80
Notch signal integration in the vasculature during remodeling. Vascul Pharmacol (2014) 0.80
Copy number variations in endoglin locus: mapping of large deletions in Spanish families with hereditary hemorrhagic telangiectasia type 1. BMC Med Genet (2013) 0.79
Cryptic collagen IV promotes cell migration and adhesion in myeloid leukemia. Cancer Med (2014) 0.79
Bazedoxifene, a new orphan drug for the treatment of bleeding in hereditary haemorrhagic telangiectasia. Thromb Haemost (2016) 0.78
The LTR promoter of the rat oncomodulin gene is regulated by cell-line specific accessibility in the LTR U3 region. Arch Biochem Biophys (2006) 0.77
Transient injury-dependent up-regulation of CD105 and its specific targeting with an anti-vascular anti-mouse endoglin-nigrin b immunotoxin. Med Chem (2012) 0.75
Co-injection of mesenchymal stem cells with endothelial progenitor cells accelerates muscle recovery in hind limb ischemia through an endoglin-dependent mechanism. Thromb Haemost (2017) 0.75
Effect of metamizol on promyelocytic and terminally differentiated granulocytic cells. Comparative analysis with acetylsalicylic acid and diclofenac. Biochem Pharmacol (2003) 0.75