Published in Lung Cancer on July 13, 2006
Therapeutic targeting of the focal adhesion complex prevents oncogenic TGF-beta signaling and metastasis. Breast Cancer Res (2009) 1.67
TGF-β stimulates Pyk2 expression as part of an epithelial-mesenchymal transition program required for metastatic outgrowth of breast cancer. Oncogene (2012) 1.43
Focal adhesion kinase as a cancer therapy target. Anticancer Agents Med Chem (2010) 1.19
Small molecule chloropyramine hydrochloride (C4) targets the binding site of focal adhesion kinase and vascular endothelial growth factor receptor 3 and suppresses breast cancer growth in vivo. J Med Chem (2009) 1.11
Lung cancer cell migration is regulated via repressing growth factor PTN/RPTP β/ζ signaling by menin. Oncogene (2010) 1.03
Targeting FAK in human cancer: from finding to first clinical trials. Front Biosci (Landmark Ed) (2014) 0.99
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FAK-heterozygous mice display enhanced tumour angiogenesis. Nat Commun (2013) 0.92
Overexpression of focal adhesion kinase correlates with increased lymph node metastasis and poor prognosis in non-small-cell lung cancer. J Cancer Res Clin Oncol (2012) 0.89
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Role of NEDD9 in invasion and metastasis of lung adenocarcinoma. Exp Ther Med (2012) 0.81
Varied pathways of stage IA lung adenocarcinomas discovered by integrated gene expression analysis. Int J Biol Sci (2011) 0.79
The prognostic significance of focal adhesion kinase expression in stage I non-small-cell lung cancer. J Thorac Oncol (2014) 0.78
Classification of non-small cell lung cancer based on copy number alterations. PLoS One (2014) 0.77
Inhibition of cell growth and invasion by epidermal growth factor-targeted phagemid particles carrying siRNA against focal adhesion kinase in the presence of hydroxycamptothecin. BMC Biotechnol (2008) 0.77
Combination of heat shock protein 90 and focal adhesion kinase inhibitors synergistically inhibits the growth of non-small cell lung cancer cells. Oncoscience (2015) 0.77
Efficacy of focal adhesion kinase inhibition in non-small cell lung cancer with oncogenically activated MAPK pathways. Br J Cancer (2016) 0.77
Expression of pY397 FAK promotes the development of non-small cell lung cancer. Oncol Lett (2015) 0.76
Yes-mediated phosphorylation of focal adhesion kinase at tyrosine 861 increases metastatic potential of prostate cancer cells. Oncotarget (2015) 0.76
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Efficient Drug-Pathway Association Analysis via Integrative Penalized Matrix Decomposition. IEEE/ACM Trans Comput Biol Bioinform (2016) 0.75
Focal Adhesion Kinase Inhibitors in Combination with Erlotinib Demonstrate Enhanced Anti-Tumor Activity in Non-Small Cell Lung Cancer. PLoS One (2016) 0.75
Enterolactone alters FAK-Src signaling and suppresses migration and invasion of lung cancer cell lines. BMC Complement Altern Med (2017) 0.75
Prognostic Value of Focal Adhesion Kinase (FAK) in Human Solid Carcinomas: A Meta-Analysis. PLoS One (2016) 0.75
Focal adhesion kinase as an immunotherapeutic target. Cancer Immunol Immunother (2008) 0.75
Daurinol blocks breast and lung cancer metastasis and development by inhibition of focal adhesion kinase (FAK). Oncotarget (2017) 0.75
Enhanced efficacy of AKT and FAK kinase combined inhibition in squamous cell lung carcinomas with stable reduction in PTEN. Oncotarget (2017) 0.75
miR-151a induces partial EMT by regulating E-cadherin in NSCLC cells. Oncogenesis (2017) 0.75
Fatty acid synthase: a metabolic enzyme and candidate oncogene in prostate cancer. J Natl Cancer Inst (2009) 2.53
Intrapericardial left pneumonectomy after induction chemotherapy: the risk of cardiac herniation. J Thorac Cardiovasc Surg (2002) 2.05
Organ allocation waiting time during extracorporeal bridge to lung transplant affects outcomes. Chest (2013) 1.99
Pathological complete response after preoperative systemic therapy and outcome: relevance of clinical and biologic baseline features. Breast Cancer Res Treat (2010) 1.97
Banking together. A unified model of informed consent for biobanking. EMBO Rep (2008) 1.67
Tailored preoperative treatment of locally advanced triple negative (hormone receptor negative and HER2 negative) breast cancer with epirubicin, cisplatin, and infusional fluorouracil followed by weekly paclitaxel. Cancer Chemother Pharmacol (2007) 1.66
Recombinant human erythropoietin counteracts secondary injury and markedly enhances neurological recovery from experimental spinal cord trauma. Proc Natl Acad Sci U S A (2002) 1.66
Invasive ductal carcinoma of the breast with the "triple-negative" phenotype: prognostic implications of EGFR immunoreactivity. Breast Cancer Res Treat (2008) 1.62
Preclinical model of organotypic culture for pharmacodynamic profiling of human tumors. Proc Natl Acad Sci U S A (2010) 1.55
Pseudohypoparathyroidism and GNAS epigenetic defects: clinical evaluation of albright hereditary osteodystrophy and molecular analysis in 40 patients. J Clin Endocrinol Metab (2010) 1.53
Homing of peripherally injected bone marrow cells in rat after experimental myocardial injury. Haematologica (2003) 1.49
Does lobectomy for lung cancer in patients with chronic obstructive pulmonary disease affect lung function? A multicenter national study. J Thorac Cardiovasc Surg (2005) 1.47
Molecular and immunohistochemical analysis of HER2/neu oncogene in synovial sarcoma. Hum Pathol (2003) 1.47
Inhibitors of apoptosis proteins (IAPs) expression and their prognostic significance in hepatocellular carcinoma. BMC Cancer (2009) 1.40
Survivin gene expression in early-stage non-small cell lung cancer. J Pathol (2003) 1.35
Met activation in non-small cell lung cancer is associated with de novo resistance to EGFR inhibitors and the development of brain metastasis. Am J Pathol (2010) 1.30
Overexpression of fatty acid synthase is associated with palmitoylation of Wnt1 and cytoplasmic stabilization of beta-catenin in prostate cancer. Lab Invest (2008) 1.30
Breast phyllodes tumor: a review of literature and a single center retrospective series analysis. Crit Rev Oncol Hematol (2013) 1.30
Metabolic stress regulates cytoskeletal dynamics and metastasis of cancer cells. J Clin Invest (2013) 1.28
Metabolic alterations and targeted therapies in prostate cancer. J Pathol (2010) 1.28
High incidence of benign testicular neoplasms diagnosed by ultrasound. J Urol (2003) 1.23
Molecular and phenotypic characterization of human amniotic fluid cells and their differentiation potential. Cell Res (2006) 1.23
Genome-wide screening of copy number alterations and LOH events in renal cell carcinomas and integration with gene expression profile. Mol Cancer (2008) 1.22
MicroRNA profiling of hepatocarcinogenesis identifies C19MC cluster as a novel prognostic biomarker in hepatocellular carcinoma. Liver Int (2012) 1.18
Control of tumor bioenergetics and survival stress signaling by mitochondrial HSP90s. Cancer Cell (2012) 1.17
EGFR-targeted therapy for non-small cell lung cancer: focus on EGFR oncogenic mutation. Int J Med Sci (2013) 1.14
Biofilms formed by Candida albicans bloodstream isolates display phenotypic and transcriptional heterogeneity that are associated with resistance and pathogenicity. BMC Microbiol (2014) 1.14
The European Consensus on grading of bone marrow fibrosis allows a better prognostication of patients with primary myelofibrosis. Mod Pathol (2012) 1.13
Quantitative PCR and HER2 testing in breast cancer: a technical and cost-effectiveness analysis. Am J Clin Pathol (2008) 1.12
Invasive lobular breast cancer: subtypes and outcome. Breast Cancer Res Treat (2012) 1.11
Carcinosarcoma of the colon: report of a case with morphological, ultrastructural and molecular analysis. BMC Cancer (2006) 1.11
Ultrasonography-guided transbronchial needle aspiration and microRNA: return to the past? Ann Thorac Surg (2013) 1.08
Helicobacter pylori-negative Russell body gastritis: case report. World J Gastroenterol (2011) 1.07
Methylprednisolone neutralizes the beneficial effects of erythropoietin in experimental spinal cord injury. Proc Natl Acad Sci U S A (2005) 1.07
Clinicopathologic characteristics of invasive lobular carcinoma of the breast: results of an analysis of 530 cases from a single institution. Cancer (2008) 1.06
Survivin gene expression in chronic liver disease and hepatocellular carcinoma. Hepatogastroenterology (2008) 1.05
Heterogeneity of triple-negative breast cancer: histologic subtyping to inform the outcome. Clin Breast Cancer (2012) 1.05
HER-2/Neu alterations in non-small cell lung cancer: a comprehensive evaluation by real time reverse transcription-PCR, fluorescence in situ hybridization, and immunohistochemistry. Clin Cancer Res (2003) 1.00
Schwann cell hamartoma: case report. BMC Gastroenterol (2011) 1.00
Isolation and growth of smooth muscle-like cells derived from tuberous sclerosis complex-2 human renal angiomyolipoma: epidermal growth factor is the required growth factor. Am J Pathol (2005) 1.00
Proliferation of transformed somatotroph cells related to low or absent expression of protein kinase a regulatory subunit 1A protein. Cancer Res (2004) 0.99
Reparixin, an inhibitor of CXCR2 function, attenuates inflammatory responses and promotes recovery of function after traumatic lesion to the spinal cord. J Pharmacol Exp Ther (2007) 0.99
Pathologic complete remission rate after cisplatin-based primary chemotherapy in breast cancer: correlation with p63 expression. Cancer Chemother Pharmacol (2007) 0.98
Quantitative real-time polymerase chain reaction detection of lymph node lung cancer micrometastasis using carcinoembryonic antigen marker. Chest (2005) 0.97
Identification of potential therapeutic targets in malignant mesothelioma using cell-cycle gene expression analysis. Am J Pathol (2009) 0.96
The microRNA cluster C19MC is deregulated in parathyroid tumours. J Mol Endocrinol (2012) 0.95
Serum biomarkers of renal cell carcinoma assessed using a protein profiling approach based on ClinProt technique. Urology (2009) 0.95
Prediction of survival in stage I lung carcinoma patients by telomerase function evaluation. Lab Invest (2002) 0.94
Survivin family proteins as novel molecular determinants of doxorubicin resistance in organotypic human breast tumors. Breast Cancer Res (2014) 0.93
Role of Strain Rate in the Pathogenesis of Ventilator-Induced Lung Edema. Crit Care Med (2016) 0.93
MicroRNA-425-3p predicts response to sorafenib therapy in patients with hepatocellular carcinoma. Liver Int (2014) 0.93
Expression of endothelial protein C receptor and thrombomodulin in the intestinal tissue of patients with inflammatory bowel disease. Crit Care Med (2004) 0.92
HER2 in gastric cancer: a digital image analysis in pre-neoplastic, primary and metastatic lesions. Mod Pathol (2013) 0.92
Pirin inhibits cellular senescence in melanocytic cells. Am J Pathol (2011) 0.92
Adult neural precursors isolated from post mortem brain yield mostly neurons: an erythropoietin-dependent process. Neurobiol Dis (2011) 0.91
Regulation of lung cancer metastasis by Klf4-Numb-like signaling. Cancer Res (2013) 0.91
Protein kinase A regulatory subunits in human adipose tissue: decreased R2B expression and activity in adipocytes from obese subjects. Diabetes (2008) 0.91
FGFR4 Gly388Arg polymorphism may affect the clinical stage of patients with lung cancer by modulating the transcriptional profile of normal lung. Int J Cancer (2009) 0.91
Aberrant overexpression of the cell polarity module scribble in human cancer. Am J Pathol (2011) 0.91
Lymphomas of the bone: a pathological and clinical study of 54 cases. Int J Surg Pathol (2002) 0.91
The methylation of the TSC2 promoter underlies the abnormal growth of TSC2 angiomyolipoma-derived smooth muscle cells. Am J Pathol (2009) 0.90
Sarcoma of the breast: outcome and reconstructive options. Clin Breast Cancer (2012) 0.89
SEL1L expression in non-small cell lung cancer. Hum Pathol (2006) 0.89
Viability-dependent promoting action of adult neural precursors in spinal cord injury. Mol Med (2008) 0.88
The significance of bone marrow biopsy and JAK2V617F mutation in the differential diagnosis between the "early" prepolycythemic phase of polycythemia vera and essential thrombocythemia. Am J Clin Pathol (2008) 0.88
Survivin expression in tuberous sclerosis complex cells. Mol Med (2007) 0.88
Gene expression signature of non-involved lung tissue associated with survival in lung adenocarcinoma patients. Carcinogenesis (2013) 0.88
Anti-EGFR antibody efficiently and specifically inhibits human TSC2-/- smooth muscle cell proliferation. Possible treatment options for TSC and LAM. PLoS One (2008) 0.87
Single exposure to erythropoietin modulates Nerve Growth Factor expression in the spinal cord following traumatic injury: comparison with methylprednisolone. Eur J Pharmacol (2007) 0.87
Lymphangioleiomyomatosis and TSC2-/- cells. Lymphat Res Biol (2010) 0.87
Multiple genetic loci modulate lung adenocarcinoma clinical staging. Clin Cancer Res (2011) 0.86