Published in Biochim Biophys Acta on June 07, 2006
Untargeted metabolomics identifies enterobiome metabolites and putative uremic toxins as substrates of organic anion transporter 1 (Oat1). J Proteome Res (2011) 1.18
Oat5 and NaDC1 protein abundance in kidney and urine after renal ischemic reperfusion injury. J Histochem Cytochem (2008) 0.84
Drug disposition alterations in liver disease: extrahepatic effects in cholestasis and nonalcoholic steatohepatitis. Expert Opin Drug Metab Toxicol (2014) 0.81
Endocrine and metabolic regulation of renal drug transporters. J Biochem Mol Toxicol (2012) 0.80
Renal elimination of organic anions in cholestasis. World J Gastroenterol (2008) 0.79
Expression and function of renal and hepatic organic anion transporters in extrahepatic cholestasis. World J Gastroenterol (2012) 0.79
Adaptive response to increased bile acids: induction of MDR1 gene expression and P-glycoprotein activity in renal epithelial cells. Pflugers Arch (2007) 0.78
Renal xenobiotic transporter expression is altered in multiple experimental models of nonalcoholic steatohepatitis. Drug Metab Dispos (2014) 0.77
Evaluation of chinese-herbal-medicine-induced herb-drug interactions: focusing on organic anion transporter 1. Evid Based Complement Alternat Med (2012) 0.77
Expression of renal Oat5 and NaDC1 transporters in rats with acute biliary obstruction. World J Gastroenterol (2015) 0.75
Arsenic and Mercury Containing Traditional Chinese Medicine (Realgar and Cinnabar) Strongly Inhibit Organic Anion Transporters, Oat1 and Oat3, In Vivo in Mice. Biomed Res Int (2015) 0.75
Posttranslational Regulation of Organic Anion Transporters by Ubiquitination: Known and Novel. Med Res Rev (2016) 0.75
Molecular identification of a renal urate anion exchanger that regulates blood urate levels. Nature (2002) 5.62
CATs and HATs: the SLC7 family of amino acid transporters. Pflugers Arch (2003) 2.69
Common defects of ABCG2, a high-capacity urate exporter, cause gout: a function-based genetic analysis in a Japanese population. Sci Transl Med (2009) 2.25
Mutations in glucose transporter 9 gene SLC2A9 cause renal hypouricemia. Am J Hum Genet (2008) 2.21
Plasma urate level is directly regulated by a voltage-driven urate efflux transporter URATv1 (SLC2A9) in humans. J Biol Chem (2008) 2.09
New insights into renal transport of urate. Curr Opin Rheumatol (2007) 2.07
The SLC22 drug transporter family. Pflugers Arch (2003) 1.95
Clinical and molecular analysis of patients with renal hypouricemia in Japan-influence of URAT1 gene on urinary urate excretion. J Am Soc Nephrol (2004) 1.87
Human vascular smooth muscle cells express a urate transporter. J Am Soc Nephrol (2006) 1.83
Molecular physiology of urate transport. Physiology (Bethesda) (2005) 1.69
Transport of 99mTc-MAG3 via rat renal organic anion transporter 1. J Nucl Med (2004) 1.66
L-type amino acid transporter 1 as a potential molecular target in human astrocytic tumors. Int J Cancer (2006) 1.57
L-type amino-acid transporter 1 as a novel biomarker for high-grade malignancy in prostate cancer. Pathol Int (2009) 1.57
Human organic anion transporter 4 is a renal apical organic anion/dicarboxylate exchanger in the proximal tubules. J Pharmacol Sci (2004) 1.52
Mutations in SLC6A19, encoding B0AT1, cause Hartnup disorder. Nat Genet (2004) 1.45
Molecular physiology of renal organic anion transporters. Am J Physiol Renal Physiol (2006) 1.44
Transport of amino acid-related compounds mediated by L-type amino acid transporter 1 (LAT1): insights into the mechanisms of substrate recognition. Mol Pharmacol (2002) 1.44
Rat renal cortical OAT1 and OAT3 exhibit gender differences determined by both androgen stimulation and estrogen inhibition. Am J Physiol Renal Physiol (2004) 1.43
A novel role of the C-terminus of b 0,+ AT in the ER-Golgi trafficking of the rBAT-b 0,+ AT heterodimeric amino acid transporter. Biochem J (2009) 1.41
The multivalent PDZ domain-containing protein PDZK1 regulates transport activity of renal urate-anion exchanger URAT1 via its C terminus. J Biol Chem (2004) 1.40
l-type amino acid transporter 1 and CD98 expression in primary and metastatic sites of human neoplasms. Cancer Sci (2008) 1.37
The SLC3 and SLC7 families of amino acid transporters. Mol Aspects Med (2013) 1.36
Identification of a novel system L amino acid transporter structurally distinct from heterodimeric amino acid transporters. J Biol Chem (2003) 1.34
Organic anion transporter family: current knowledge. J Pharmacol Sci (2006) 1.34
Uric acid causes vascular smooth muscle cell proliferation by entering cells via a functional urate transporter. Am J Nephrol (2005) 1.33
Role of organic anion transporters in the tubular transport of indoxyl sulfate and the induction of its nephrotoxicity. J Am Soc Nephrol (2002) 1.32
Human organic anion transporters and human organic cation transporters mediate renal antiviral transport. J Pharmacol Exp Ther (2002) 1.31
Common dysfunctional variants in ABCG2 are a major cause of early-onset gout. Sci Rep (2013) 1.28
Roles of organic anion transporters (OATs) and a urate transporter (URAT1) in the pathophysiology of human disease. Clin Exp Nephrol (2005) 1.27
Interactions of human organic anion transporters with diuretics. J Pharmacol Exp Ther (2003) 1.25
A high prevalence of renal hypouricemia caused by inactive SLC22A12 in Japanese. Kidney Int (2004) 1.24
Mammalian target of rapamycin signalling modulates amino acid uptake by regulating transporter cell surface abundance in primary human trophoblast cells. J Physiol (2012) 1.23
Maternal protein restriction in the rat inhibits placental insulin, mTOR, and STAT3 signaling and down-regulates placental amino acid transporters. Endocrinology (2011) 1.23
High expression of L-type amino-acid transporter 1 (LAT1) in gastric carcinomas: comparison with non-cancerous lesions. Pathol Int (2011) 1.22
Inhibition of L-type amino acid transporter 1 has antitumor activity in non-small cell lung cancer. Anticancer Res (2010) 1.20
Mutational and functional analysis of SLC4A4 in a patient with proximal renal tubular acidosis. Pflugers Arch (2004) 1.19
Cyclosporin A and its analogs inhibit hepatitis B virus entry into cultured hepatocytes through targeting a membrane transporter, sodium taurocholate cotransporting polypeptide (NTCP). Hepatology (2014) 1.19
LAT1 expression is closely associated with hypoxic markers and mTOR in resected non-small cell lung cancer. Am J Transl Res (2011) 1.16
Sodium-dependent phosphate cotransporter type 1 sequence polymorphisms in male patients with gout. Ann Rheum Dis (2009) 1.16
Localization of Ang-1, -2, Tie-2, and VEGF expression at endothelial-pericyte interdigitation in rat angiogenesis. Lab Invest (2006) 1.15
Immunolocalization of multispecific organic anion transporters, OAT1, OAT2, and OAT3, in rat kidney. J Am Soc Nephrol (2002) 1.14
Enhanced tumor growth elicited by L-type amino acid transporter 1 in human malignant glioma cells. Neurosurgery (2008) 1.14
L-type amino acid transporter 1 inhibitors inhibit tumor cell growth. Cancer Sci (2009) 1.13
Characterization of uremic toxin transport by organic anion transporters in the kidney. Kidney Int (2004) 1.11
Correlation of L-type amino acid transporter 1 and CD98 expression with triple negative breast cancer prognosis. Cancer Sci (2011) 1.11
Function and localization of urate transporter 1 in mouse kidney. J Am Soc Nephrol (2004) 1.11
Characterization of the system L amino acid transporter in T24 human bladder carcinoma cells. Biochim Biophys Acta (2002) 1.10
Characterization of methotrexate transport and its drug interactions with human organic anion transporters. J Pharmacol Exp Ther (2002) 1.10
Novel liver-specific organic anion transporter OAT7 that operates the exchange of sulfate conjugates for short chain fatty acid butyrate. Hepatology (2007) 1.09
Human sodium phosphate transporter 4 (hNPT4/SLC17A3) as a common renal secretory pathway for drugs and urate. J Biol Chem (2010) 1.09
Novel single nucleotide polymorphisms of organic cation transporter 1 (SLC22A1) affecting transport functions. Biochem Biophys Res Commun (2004) 1.09
System L amino acid transporter inhibitor enhances anti-tumor activity of cisplatin in a head and neck squamous cell carcinoma cell line. Cancer Lett (2008) 1.08
Fluorine-18-alpha-methyltyrosine positron emission tomography for diagnosis and staging of lung cancer: a clinicopathologic study. Clin Cancer Res (2007) 1.07
The human T-type amino acid transporter-1: characterization, gene organization, and chromosomal location. Genomics (2002) 1.07
CD98 expression is associated with poor prognosis in resected non-small-cell lung cancer with lymph node metastases. Ann Surg Oncol (2009) 1.07
LAT1 is a critical transporter of essential amino acids for immune reactions in activated human T cells. J Immunol (2013) 1.07
Amino acid transporter LAT3 is required for podocyte development and function. J Am Soc Nephrol (2009) 1.06
Chronic maternal infusion of full-length adiponectin in pregnant mice down-regulates placental amino acid transporter activity and expression and decreases fetal growth. J Physiol (2012) 1.06
Interaction of human organic anion transporters 2 and 4 with organic anion transport inhibitors. J Pharmacol Exp Ther (2002) 1.05
Expression of LAT1 predicts risk of progression of transitional cell carcinoma of the upper urinary tract. Virchows Arch (2007) 1.05
Dual-color imaging of nuclear-cytoplasmic dynamics, viability, and proliferation of cancer cells in the portal vein area. Cancer Res (2006) 1.04
Disease-causing missense mutations in NPHS2 gene alter normal nephrin trafficking to the plasma membrane. Kidney Int (2004) 1.04
Lysophosphatidylcholine enhances cytokine production of endothelial cells via induction of L-type amino acid transporter 1 and cell surface antigen 4F2. Arterioscler Thromb Vasc Biol (2004) 1.03
Type 1 sodium-dependent phosphate transporter (SLC17A1 Protein) is a Cl(-)-dependent urate exporter. J Biol Chem (2010) 1.03
Modulation of renal apical organic anion transporter 4 function by two PDZ domain-containing proteins. J Am Soc Nephrol (2005) 1.03