Published in Bioconjug Chem on July 19, 2006
Dependence of self-tolerance on TRAF6-directed development of thymic stroma. Science (2005) 1.91
Potent antitumor activity of interleukin-27. Cancer Res (2004) 1.80
An indispensable role for STAT1 in IL-27-induced T-bet expression but not proliferation of naive CD4+ T cells. J Immunol (2004) 1.66
Regulation of antitumor immune responses by the IL-12 family cytokines, IL-12, IL-23, and IL-27. Clin Dev Immunol (2010) 1.59
MR analysis of the substantia innominata in normal aging, Alzheimer disease, and other types of dementia. AJNR Am J Neuroradiol (2002) 1.59
Phosphorylation of the adaptor ASC acts as a molecular switch that controls the formation of speck-like aggregates and inflammasome activity. Nat Immunol (2013) 1.51
Antiangiogenic and antitumor activities of IL-27. J Immunol (2006) 1.50
Augmentation of effector CD8+ T cell generation with enhanced granzyme B expression by IL-27. J Immunol (2005) 1.50
IL-27 suppresses Th2 cell development and Th2 cytokines production from polarized Th2 cells: a novel therapeutic way for Th2-mediated allergic inflammation. J Immunol (2007) 1.50
Evaluation of pharmacogenetic algorithm for warfarin dose requirements in Japanese patients. Circ J (2010) 1.49
A role for IL-27 in early regulation of Th1 differentiation. J Immunol (2005) 1.45
IL-27 suppresses CD28-mediated [correction of medicated] IL-2 production through suppressor of cytokine signaling 3. J Immunol (2006) 1.34
Antiproliferative activity of IL-27 on melanoma. J Immunol (2008) 1.33
Pivotal roles of T-helper 17-related cytokines, IL-17, IL-22, and IL-23, in inflammatory diseases. Clin Dev Immunol (2013) 1.20
Calpain-induced Bax-cleavage product is a more potent inducer of apoptotic cell death than wild-type Bax. Cancer Lett (2003) 1.18
IL-27 induces Th1 differentiation via p38 MAPK/T-bet- and intercellular adhesion molecule-1/LFA-1/ERK1/2-dependent pathways. J Immunol (2006) 1.15
Phase I study of alpha-galactosylceramide-pulsed antigen presenting cells administration to the nasal submucosa in unresectable or recurrent head and neck cancer. Cancer Immunol Immunother (2007) 1.14
CCR7 ligands are required for development of experimental autoimmune encephalomyelitis through generating IL-23-dependent Th17 cells. J Immunol (2009) 1.13
Cerebral microbleeds in Alzheimer's disease. J Neurol (2003) 1.07
Essential role of IkappaB kinase alpha in thymic organogenesis required for the establishment of self-tolerance. J Immunol (2006) 1.07
Induction of IgG2a class switching in B cells by IL-27. J Immunol (2004) 1.07
TGF-beta is necessary for induction of IL-23R and Th17 differentiation by IL-6 and IL-23. Biochem Biophys Res Commun (2009) 1.05
Interleukin-27 directly induces differentiation in hematopoietic stem cells. Blood (2007) 1.05
Cloning and analysis of the telomere and terminal inverted repeat of the linear chromosome of Streptomyces griseus. J Bacteriol (2002) 1.03
Increased blood-brain barrier permeability in white matter lesions of Binswanger's disease evaluated by contrast-enhanced MRI. Dement Geriatr Cogn Disord (2002) 1.02
Antigen chemically coupled to the surface of liposomes are cross-presented to CD8+ T cells and induce potent antitumor immunity. J Immunol (2006) 1.02
STAT3 is indispensable to IL-27-mediated cell proliferation but not to IL-27-induced Th1 differentiation and suppression of proinflammatory cytokine production. J Immunol (2008) 1.01
Experimental manufacture of equine antivenom against yamakagashi (Rhabdophis tigrinus). Jpn J Infect Dis (2011) 0.99
Regulation of osteoclastogenesis by three human RANKL isoforms expressed in NIH3T3 cells. Biochem Biophys Res Commun (2004) 0.96
Multimerization of the receptor activator of nuclear factor-kappaB ligand (RANKL) isoforms and regulation of osteoclastogenesis. J Biol Chem (2003) 0.96
Induction of apoptosis and/or necrosis following exposure to antitumour agents in a melanoma cell line, probably through modulation of Bcl-2 family proteins. Melanoma Res (2003) 0.95
Catechin safely improved higher levels of fatness, blood pressure, and cholesterol in children. Obesity (Silver Spring) (2008) 0.95
Regulation of the development of acute hepatitis by IL-23 through IL-22 and IL-17 production. Eur J Immunol (2011) 0.93
The prokinetic effect of mosapride citrate combined with omeprazole therapy improves clinical symptoms and gastric emptying in PPI-resistant NERD patients with delayed gastric emptying. J Gastroenterol (2009) 0.93
Transient lower esophageal sphincter relaxations (TLESRs) are the major mechanism of gastroesophageal reflux but are not the cause of reflux disease. Dig Dis Sci (2005) 0.93
Sustained upregulation of effector natural killer cells in chronic myeloid leukemia after discontinuation of imatinib. Cancer Sci (2013) 0.93
A pivotal role for interleukin-27 in CD8+ T cell functions and generation of cytotoxic T lymphocytes. J Biomed Biotechnol (2010) 0.93
Role for Btg1 and Btg2 in growth arrest of WEHI-231 cells through arginine methylation following membrane immunoglobulin engagement. Exp Cell Res (2007) 0.92
MR features of the substantia innominata and therapeutic implications in dementias. Neurobiol Aging (2006) 0.92
Possible recruitment of peripheral blood CXCR3+ CD27+ CD19+ B cells to the liver of chronic hepatitis C patients. J Interferon Cytokine Res (2010) 0.92
Positive modulation of IL-12 signaling by sphingosine kinase 2 associating with the IL-12 receptor beta 1 cytoplasmic region. J Immunol (2003) 0.91
A CTL-based liposomal vaccine capable of inducing protection against heterosubtypic influenza viruses in HLA-A*0201 transgenic mice. Biochem Biophys Res Commun (2010) 0.89
IL-27 enhances the expression of TRAIL and TLR3 in human melanomas and inhibits their tumor growth in cooperation with a TLR3 agonist poly(I:C) partly in a TRAIL-dependent manner. PLoS One (2013) 0.89
Nocardioides aromaticivorans sp. nov., a dibenzofuran-degrading bacterium isolated from dioxin-polluted environments. Syst Appl Microbiol (2005) 0.89
Requirement of c-Jun NH2-terminal kinase activation in interferon-alpha-induced apoptosis through upregulation of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) in Daudi B lymphoma cells. Exp Cell Res (2005) 0.89
Synthetic peptides coupled to the surface of liposomes effectively induce SARS coronavirus-specific cytotoxic T lymphocytes and viral clearance in HLA-A*0201 transgenic mice. Vaccine (2009) 0.88
Tumor necrosis factor-related apoptosis-inducing ligand induces apoptotic cell death through c-Jun NH2-terminal kinase activation in squamous cell carcinoma cells. Oncol Rep (2009) 0.87
Synergistic antitumor effect by coexpression of chemokine CCL21/SLC and costimulatory molecule LIGHT. Cancer Gene Ther (2004) 0.86
Peptides coupled to the surface of a kind of liposome protect infection of influenza viruses. Vaccine (2007) 0.86
Liposome-coupled antigens are internalized by antigen-presenting cells via pinocytosis and cross-presented to CD8 T cells. PLoS One (2010) 0.86
The appearance of rosette-like esophageal folds ("esophageal rosette") in the lower esophagus after a deep inspiration is a characteristic endoscopic finding of primary achalasia. J Gastroenterol (2009) 0.86
Acid and non-acid reflux in Japanese patients with non-erosive reflux disease with persistent reflux symptoms, despite taking a double-dose of proton pump inhibitor: a study using combined pH-impedance monitoring. J Gastroenterol (2009) 0.86
IL-27 suppresses RANKL expression in CD4+ T cells in part through STAT3. Immunol Lett (2011) 0.85
Interferon-alpha induces transient upregulation of c-FLIP through NF-kappaB activation. Exp Cell Res (2007) 0.85
Dendritic cell maturation by CD11c- T cells and Valpha24+ natural killer T-cell activation by alpha-galactosylceramide. Int J Cancer (2005) 0.85
Interferon-alpha-induced apoptosis via tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-dependent and -independent manner. Oncol Rep (2007) 0.85
CCR7 ligands up-regulate IL-23 through PI3-kinase and NF-κ B pathway in dendritic cells. J Leukoc Biol (2012) 0.84
Differences in MR features of the substantia innominata between dementia with Lewy bodies and Alzheimer's disease. J Neurol (2005) 0.84
Blockade of the OX40 ligand prolongs corneal allograft survival. Eur J Immunol (2007) 0.84
Chromosomal circularization in Streptomyces griseus by nonhomologous recombination of deletion ends. Biosci Biotechnol Biochem (2003) 0.83
Irradiation up-regulates CD80 expression through two different mechanisms in spleen B cells, B lymphoma cells, and dendritic cells. Immunology (2004) 0.83
Cerebral microbleeds in Binswanger's disease: a gradient-echo T2*-weighted magnetic resonance imaging study. Neurosci Lett (2003) 0.83
Interleukins and cancer immunotherapy. Immunotherapy (2009) 0.83
Chemotherapeutic agents sensitize sarcoma cell lines to tumor necrosis factor-related apoptosis-inducing ligand-induced caspase-8 activation, apoptosis and loss of mitochondrial membrane potential. J Orthop Res (2003) 0.83
Apoptosis induced by chemotherapeutic agents involves c-Jun N-terminal kinase activation in sarcoma cell lines. J Orthop Res (2006) 0.82
Highly efficient antiviral CD8+ T-cell induction by peptides coupled to the surfaces of liposomes. Clin Vaccine Immunol (2009) 0.82
Atrophy of the substantia innominata on magnetic resonance imaging and response to donepezil treatment in Alzheimer's disease. Neurosci Lett (2002) 0.82
DNA vaccine using invariant chain gene for delivery of CD4+ T cell epitope peptide derived from Japanese cedar pollen allergen inhibits allergen-specific IgE response. Eur J Immunol (2002) 0.81
PKC-δ mediates interferon-α-induced apoptosis through c-Jun NH₂-terminal kinase activation. BMC Cell Biol (2012) 0.81
Defective triggering of secondary peristalsis in patients with non-erosive reflux disease. J Gastroenterol Hepatol (2007) 0.81
Development and function of cortical thymic epithelial cells. Curr Top Microbiol Immunol (2014) 0.81
C-jun N-terminal kinase activation is required for apoptotic cell death induced by TNF-related apoptosis-inducing ligand plus DNA-damaging agents in sarcoma cell lines. Anticancer Res (2006) 0.81
Interferon-beta-induced activation of c-Jun NH2-terminal kinase mediates apoptosis through up-regulation of CD95 in CH31 B lymphoma cells. Exp Cell Res (2004) 0.81
Efficient induction of cytotoxic T lymphocytes specific for severe acute respiratory syndrome (SARS)-associated coronavirus by immunization with surface-linked liposomal peptides derived from a non-structural polyprotein 1a. Antiviral Res (2009) 0.81
Irradiation up-regulates CD80 expression through induction of tumour necrosis factor-alpha and CD40 ligand expression on B lymphoma cells. Immunology (2002) 0.81
Intracellular calcium response and adhesiveness of chick embryonic retinal neurons to photoelectric dye-coupled polyethylene films as prototypes of retinal prostheses. Artif Organs (2006) 0.81
Differences in magnetization transfer ratios of the hippocampus between dementia with Lewy bodies and Alzheimer's disease. Neurosci Lett (2005) 0.81
Glial reaction to photoelectric dye-based retinal prostheses implanted in the subretinal space of rats. J Artif Organs (2008) 0.81
Requirement for JNK-dependent upregulation of BimL in anti-IgM-induced apoptosis in murine B lymphoma cell lines WEHI-231 and CH31. Exp Cell Res (2006) 0.80
Enforced expression of a truncated form of Bax-alpha (tBax) driven by human telomerase reverse transcriptase (hTERT) promoter sensitizes tumor cells to chemotherapeutic agents or tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). Anticancer Res (2006) 0.80
Id3-mediated enhancement of cisplatin-induced apoptosis in a sarcoma cell line MG-63. Anticancer Res (2004) 0.80
Anticancer effects of phenoxazine derivatives combined with tumor necrosis factor-related apoptosis-inducing ligand on pancreatic cancer cell lines, KLM-1 and MIA-PaCa-2. Oncol Rep (2006) 0.80
Growth arrest and DNA damage-inducible protein (GADD34) enhanced liver inflammation and tumorigenesis in a diethylnitrosamine (DEN)-treated murine model. Cancer Immunol Immunother (2015) 0.80
Exacerbation of BMI after cessation of growth hormone therapy in patients with Prader-Willi syndrome. Am J Med Genet A (2014) 0.79
Association between reflux esophagitis and/or hiatus hernia and gastric mucosal atrophy level in Japan. J Gastroenterol Hepatol (2007) 0.79