Published in Curr Top Microbiol Immunol on January 01, 2014
Prolongevity hormone FGF21 protects against immune senescence by delaying age-related thymic involution. Proc Natl Acad Sci U S A (2016) 1.41
From pre-DP, post-DP, SP4, and SP8 Thymocyte Cell Counts to a Dynamical Model of Cortical and Medullary Selection. Front Immunol (2014) 0.83
The Thymic Orchestration Involving Aire, miRNAs, and Cell-Cell Interactions during the Induction of Central Tolerance. Front Immunol (2015) 0.82
Inhibins tune the thymocyte selection process by regulating thymic stromal cell differentiation. J Immunol Res (2015) 0.78
Bioengineering Thymus Organoids to Restore Thymic Function and Induce Donor-Specific Immune Tolerance to Allografts. Mol Ther (2015) 0.77
Generation of diversity in thymic epithelial cells. Nat Rev Immunol (2017) 0.76
LTβR controls thymic portal endothelial cells for haematopoietic progenitor cell homing and T-cell regeneration. Nat Commun (2016) 0.75
Regulation of CD8+ T cell development by thymus-specific proteasomes. Science (2007) 3.11
The tumor necrosis factor family receptors RANK and CD40 cooperatively establish the thymic medullary microenvironment and self-tolerance. Immunity (2008) 2.81
The cytokine RANKL produced by positively selected thymocytes fosters medullary thymic epithelial cells that express autoimmune regulator. Immunity (2008) 2.57
CCR7 signals are essential for cortex-medulla migration of developing thymocytes. J Exp Med (2004) 2.52
Reduced Numbers and Proapoptotic Features of Mucosal-associated Invariant T Cells as a Characteristic Finding in Patients with Inflammatory Bowel Disease. Inflamm Bowel Dis (2015) 2.13
CCR7-dependent cortex-to-medulla migration of positively selected thymocytes is essential for establishing central tolerance. Immunity (2006) 2.12
Autoantigen-specific interactions with CD4+ thymocytes control mature medullary thymic epithelial cell cellularity. Immunity (2008) 2.07
IAN family critically regulates survival and development of T lymphocytes. PLoS Biol (2006) 1.95
Rank signaling links the development of invariant γδ T cell progenitors and Aire(+) medullary epithelium. Immunity (2012) 1.94
NF-kappa B-inducing kinase establishes self-tolerance in a thymic stroma-dependent manner. J Immunol (2004) 1.92
Dependence of self-tolerance on TRAF6-directed development of thymic stroma. Science (2005) 1.91
Development of autoimmunity against transcriptionally unrepressed target antigen in the thymus of Aire-deficient mice. J Immunol (2005) 1.88
Aire-dependent production of XCL1 mediates medullary accumulation of thymic dendritic cells and contributes to regulatory T cell development. J Exp Med (2011) 1.87
Thymic epithelial cells: working class heroes for T cell development and repertoire selection. Trends Immunol (2012) 1.85
Defective brain development in mice lacking the Hif-1alpha gene in neural cells. Mol Cell Biol (2003) 1.75
Coordination between CCR7- and CCR9-mediated chemokine signals in prevascular fetal thymus colonization. Blood (2006) 1.66
A systematic genome-wide screen for mutations affecting organogenesis in Medaka, Oryzias latipes. Mech Dev (2004) 1.65
Possible link between ulcerative colitis and in situ adenocarcinoma of an appendiceal mucocele: importance of inflammation in the appendiceal orifice related to UC. Inflamm Bowel Dis (2008) 1.59
Keratinocyte growth factor (KGF) enhances postnatal T-cell development via enhancements in proliferation and function of thymic epithelial cells. Blood (2007) 1.51
Effect and safety of granulocyte-monocyte adsorption apheresis for patients with ulcerative colitis positive for cytomegalovirus in comparison with immunosuppressants. Digestion (2011) 1.50
Deletion of the RAG2 C terminus leads to impaired lymphoid development in mice. Proc Natl Acad Sci U S A (2003) 1.49
Tacrolimus therapy as an alternative to thiopurines for maintaining remission in patients with refractory ulcerative colitis. J Clin Gastroenterol (2011) 1.47
Role for CCR7 ligands in the emigration of newly generated T lymphocytes from the neonatal thymus. Immunity (2002) 1.46
Activation-induced cytidine deaminase links between inflammation and the development of colitis-associated colorectal cancers. Gastroenterology (2008) 1.37
Direct comparison of Dll1- and Dll4-mediated Notch activation levels shows differential lymphomyeloid lineage commitment outcomes. J Immunol (2010) 1.37
The lymphocyte guard-IANs: regulation of lymphocyte survival by IAN/GIMAP family proteins. Trends Immunol (2006) 1.34
Experimental immune-mediated pancreatitis in neonatally thymectomized mice immunized with carbonic anhydrase II and lactoferrin. Lab Invest (2002) 1.31
Thymoproteasome shapes immunocompetent repertoire of CD8+ T cells. Immunity (2009) 1.29
Usefulness of quantitative real-time PCR assay for early detection of cytomegalovirus infection in patients with ulcerative colitis refractory to immunosuppressive therapies. Inflamm Bowel Dis (2007) 1.28
Elimination of local macrophages in intestine prevents chronic colitis in interleukin-10-deficient mice. Dig Dis Sci (2003) 1.28
Role of double-balloon endoscopy in the diagnosis of small-bowel tumors: the first Japanese multicenter study. Gastrointest Endosc (2009) 1.26
Gastrointestinal follicular lymphoma: review of the literature. J Gastroenterol (2010) 1.26
Increased frequency of aberrant V(D)J recombination products in core RAG-expressing mice. Nucleic Acids Res (2004) 1.26
An open-label prospective randomized multicenter study shows very rapid remission of ulcerative colitis by intensive granulocyte and monocyte adsorptive apheresis as compared with routine weekly treatment. Am J Gastroenterol (2009) 1.24
The role of CCL21 in recruitment of T-precursor cells to fetal thymi. Blood (2004) 1.24
Spatial mapping of thymic stromal microenvironments reveals unique features influencing T lymphoid differentiation. Immunity (2009) 1.20
Lymphotoxin signals from positively selected thymocytes regulate the terminal differentiation of medullary thymic epithelial cells. J Immunol (2010) 1.20
Identification of a novel autoantibody against pancreatic secretory trypsin inhibitor in patients with autoimmune pancreatitis. Pancreas (2006) 1.20
Cellular and molecular events during early thymus development. Immunol Rev (2006) 1.19
The role of Hes genes in intestinal development, homeostasis and tumor formation. Development (2012) 1.16
Prevalence of non-steroidal anti-inflammatory drug-induced enteropathy determined by double-balloon endoscopy: a Japanese multicenter study. Scand J Gastroenterol (2008) 1.15
Thymoproteasome: probable role in generating positively selecting peptides. Curr Opin Immunol (2008) 1.14
CCR7-mediated migration of developing thymocytes to the medulla is essential for negative selection to tissue-restricted antigens. Proc Natl Acad Sci U S A (2009) 1.12
Thymic microenvironments for T-cell repertoire formation. Adv Immunol (2008) 1.11
Human thioredoxin-1 ameliorates experimental murine colitis in association with suppressed macrophage inhibitory factor production. Gastroenterology (2006) 1.11
Ontogeny of thymic cortical epithelial cells expressing the thymoproteasome subunit β5t. Eur J Immunol (2011) 1.09
Blockade of CXCL12/CXCR4 axis ameliorates murine experimental colitis. J Pharmacol Exp Ther (2008) 1.08
Essential role of IkappaB kinase alpha in thymic organogenesis required for the establishment of self-tolerance. J Immunol (2006) 1.07
Controlling the thymic microenvironment. Curr Opin Immunol (2005) 1.04
Aire-expressing thymic medullary epithelial cells originate from β5t-expressing progenitor cells. Proc Natl Acad Sci U S A (2013) 1.04
T cell-specific disruption of arylhydrocarbon receptor nuclear translocator (Arnt) gene causes resistance to 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced thymic involution. J Immunol (2003) 1.04
Involvement of myeloid dendritic cells in the development of gastric secondary lymphoid follicles in Helicobacter pylori-infected neonatally thymectomized BALB/c mice. Infect Immun (2003) 1.03
Antigen chemically coupled to the surface of liposomes are cross-presented to CD8+ T cells and induce potent antitumor immunity. J Immunol (2006) 1.02
Lymphotoxin β receptor regulates the development of CCL21-expressing subset of postnatal medullary thymic epithelial cells. J Immunol (2013) 1.01
A case of autoimmune pancreatitis associated with sclerosing cholangitis, retroperitoneal fibrosis and Sjögren's syndrome. Pancreatology (2005) 1.01
Serial progression of cortical and medullary thymic epithelial microenvironments. Eur J Immunol (2013) 1.01
Therapeutic effects of rectal administration of basic fibroblast growth factor on experimental murine colitis. Gastroenterology (2005) 1.01
In vitro systems for the study of T cell development: fetal thymus organ culture and OP9-DL1 cell coculture. Curr Protoc Immunol (2006) 0.99
MicroRNAs control the maintenance of thymic epithelia and their competence for T lineage commitment and thymocyte selection. J Immunol (2012) 0.97
Multimerization of the receptor activator of nuclear factor-kappaB ligand (RANKL) isoforms and regulation of osteoclastogenesis. J Biol Chem (2003) 0.96
Regulation of osteoclastogenesis by three human RANKL isoforms expressed in NIH3T3 cells. Biochem Biophys Res Commun (2004) 0.96
XCL1 and XCR1 in the immune system. Microbes Infect (2011) 0.95
Cytokine crosstalk for thymic medulla formation. Curr Opin Immunol (2010) 0.93
The effect of medical treatment on patients with fistulizing Crohn's disease: a retrospective study. Intern Med (2008) 0.92
Protective roles of redox-active protein thioredoxin-1 for severe acute pancreatitis. Am J Physiol Gastrointest Liver Physiol (2005) 0.92
CCR7 deficiency in NOD mice leads to thyroiditis and primary hypothyroidism. J Immunol (2009) 0.92
Possible recruitment of peripheral blood CXCR3+ CD27+ CD19+ B cells to the liver of chronic hepatitis C patients. J Interferon Cytokine Res (2010) 0.92
Gimap3 and Gimap5 cooperate to maintain T-cell numbers in the mouse. Eur J Immunol (2013) 0.91
SR-PSOX/CXCL16 plays a critical role in the progression of colonic inflammation. Gut (2011) 0.91
IL-7 produced by thymic epithelial cells plays a major role in the development of thymocytes and TCRγδ+ intraepithelial lymphocytes. J Immunol (2013) 0.91
Solitary rectal ulcer syndrome associated with ulcerative colitis. Gastrointest Endosc (2006) 0.90
Chemokine receptor expression defines heterogeneity in the earliest thymic migrants. Eur J Immunol (2007) 0.89
Clinical features of Japanese patients with colonic angiodysplasia. J Gastroenterol Hepatol (2007) 0.88
In vivo treatment of class II MHC-deficient mice with anti-TCR antibody restores the generation of circulating CD4 T cells and optimal architecture of thymic medulla. J Immunol (2003) 0.88
Effect of EP4 agonist (ONO-4819CD) for patients with mild to moderate ulcerative colitis refractory to 5-aminosalicylates: a randomized phase II, placebo-controlled trial. Inflamm Bowel Dis (2010) 0.88
Diffuse hepatoid adenocarcinoma in the peritoneal cavity. Intern Med (2006) 0.88
Immunosuppressive effects of tacrolimus on macrophages ameliorate experimental colitis. Inflamm Bowel Dis (2010) 0.87
Sustained abdominal discomfort in a 57-year-old woman. Idiopathic mesenteric phlebosclerosis. Gut (2010) 0.87
Chemokines CCL19 and CCL21 promote activation-induced cell death of antigen-responding T cells. Blood (2006) 0.87
Refractoriness of intestinal Behçet's disease with myelodysplastic syndrome involving trisomy 8 to medical therapies - our case experience and review of the literature. Digestion (2013) 0.87
Thymic medullary epithelium and thymocyte self-tolerance require cooperation between CD28-CD80/86 and CD40-CD40L costimulatory pathways. J Immunol (2013) 0.86
A novel human fibroblast growth factor treats experimental intestinal inflammation. Gastroenterology (2002) 0.86
Liposome-coupled antigens are internalized by antigen-presenting cells via pinocytosis and cross-presented to CD8 T cells. PLoS One (2010) 0.86
Cytomegalovirus infection in patients with ulcerative colitis diagnosed by quantitative real-time PCR analysis. Dig Dis Sci (2006) 0.86
Efficacy of oral tacrolimus on intestinal Behcet's disease. Inflamm Bowel Dis (2010) 0.85
Environmental pollutant tributyltin promotes Th2 polarization and exacerbates airway inflammation. Eur J Immunol (2004) 0.85
WDR55 is a nucleolar modulator of ribosomal RNA synthesis, cell cycle progression, and teleost organ development. PLoS Genet (2008) 0.85
Thymic nurse cells provide microenvironment for secondary T cell receptor α rearrangement in cortical thymocytes. Proc Natl Acad Sci U S A (2012) 0.85
Low prevalence of CMV infection in patients with Crohn's disease in comparison with ulcerative colitis: effect of different immune response on prevalence of CMV infection. Dig Dis Sci (2010) 0.85