Published in J Huazhong Univ Sci Technolog Med Sci on January 01, 2006
A robust DNA mechanical device controlled by hybridization topology. Nature (2002) 4.45
Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor. Science (2012) 3.52
Acrolein is a major cigarette-related lung cancer agent: Preferential binding at p53 mutational hotspots and inhibition of DNA repair. Proc Natl Acad Sci U S A (2006) 2.74
Therapeutic potential of human umbilical cord mesenchymal stem cells in the treatment of rheumatoid arthritis. Arthritis Res Ther (2010) 1.90
Dipeptidyl peptidase IV inhibition for the treatment of type 2 diabetes: potential importance of selectivity over dipeptidyl peptidases 8 and 9. Diabetes (2005) 1.70
SIRT5 regulates the mitochondrial lysine succinylome and metabolic networks. Cell Metab (2013) 1.70
Mutagenicity and sequence specificity of acrolein-DNA adducts. Chem Res Toxicol (2009) 1.65
Glucagon-like peptide 1/glucagon receptor dual agonism reverses obesity in mice. Diabetes (2009) 1.65
Hypoxia-inducible factor linked to differential kidney cancer risk seen with type 2A and type 2B VHL mutations. Mol Cell Biol (2007) 1.62
Liver fat content is associated with increased carotid atherosclerosis in a Chinese middle-aged and elderly population: the Shanghai Changfeng study. Atherosclerosis (2012) 1.60
Mitochondrial protein acylation and intermediary metabolism: regulation by sirtuins and implications for metabolic disease. J Biol Chem (2012) 1.58
Nitric oxide suppresses NLRP3 inflammasome activation and protects against LPS-induced septic shock. Cell Res (2013) 1.54
pVHL acts as an adaptor to promote the inhibitory phosphorylation of the NF-kappaB agonist Card9 by CK2. Mol Cell (2007) 1.47
(E)-1-{4-[Bis(4-meth-oxy-phen-yl)meth-yl]piperazin-1-yl}-3-(3,4-dieth-oxy-phen-yl)prop-2-en-1-one ethanol disolvate. Acta Crystallogr Sect E Struct Rep Online (2012) 1.39
Elevated Th22 cells correlated with Th17 cells in patients with rheumatoid arthritis. J Clin Immunol (2011) 1.38
Association between MTR A2756G polymorphism and childhood acute lymphoblastic leukemia: a meta-analysis. Leuk Lymphoma (2013) 1.37
Double cohesion in structural DNA nanotechnology. Org Biomol Chem (2006) 1.26
Anterograde trafficking of G protein-coupled receptors: function of the C-terminal F(X)6LL motif in export from the endoplasmic reticulum. Mol Pharmacol (2008) 1.25
miR-15a and miR-16 affect the angiogenesis of multiple myeloma by targeting VEGF. Carcinogenesis (2012) 1.24
Randomized trial of the anti-FGF23 antibody KRN23 in X-linked hypophosphatemia. J Clin Invest (2014) 1.24
Lipid raft distribution of CD4 depends on its palmitoylation and association with Lck, and evidence for CD4-induced lipid raft aggregation as an additional mechanism to enhance CD3 signaling. J Immunol (2003) 1.23
Baicalin attenuates global cerebral ischemia/reperfusion injury in gerbils via anti-oxidative and anti-apoptotic pathways. Brain Res Bull (2011) 1.23
Negative regulation of Toll-like receptor signaling pathway. Microbes Infect (2009) 1.22
Omarigliptin (MK-3102): a novel long-acting DPP-4 inhibitor for once-weekly treatment of type 2 diabetes. J Med Chem (2014) 1.22
MG-132 sensitizes TRAIL-resistant prostate cancer cells by activating c-Fos/c-Jun heterodimers and repressing c-FLIP(L). Cancer Res (2007) 1.20
(E)-1-{4-[Bis(4-bromo-phen-yl)meth-yl]piperazin-1-yl}-3-(4-eth-oxy-3-meth-oxy-phen-yl)prop-2-en-1-one. Acta Crystallogr Sect E Struct Rep Online (2011) 1.19
Human organic anion-transporting polypeptide OATP-A (SLC21A3) acts in concert with P-glycoprotein and multidrug resistance protein 2 in the vectorial transport of Saquinavir in Hep G2 cells. Mol Pharm (2004) 1.18
miR-124, miR-137 and miR-340 regulate colorectal cancer growth via inhibition of the Warburg effect. Oncol Rep (2012) 1.16
Retinoblastoma tumor suppressor targets dNTP metabolism to regulate DNA replication. J Biol Chem (2002) 1.16
Bone marrow and the control of immunity. Cell Mol Immunol (2011) 1.15
miR-21 promotes migration and invasion by the miR-21-PDCD4-AP-1 feedback loop in human hepatocellular carcinoma. Oncol Rep (2012) 1.12
Impact of network structure and cellular response on spike time correlations. PLoS Comput Biol (2012) 1.12
(E)-1-{4-[Bis(4-fluoro-phen-yl)meth-yl]piperazin-1-yl}-3-(4-eth-oxy-phen-yl)prop-2-en-1-one. Acta Crystallogr Sect E Struct Rep Online (2011) 1.11
MiR-138 inhibits tumor growth through repression of EZH2 in non-small cell lung cancer. Cell Physiol Biochem (2013) 1.11
The diversity and anti-microbial activity of endophytic actinomycetes isolated from medicinal plants in Panxi plateau, China. Curr Microbiol (2010) 1.10
HIV Nef-mediated CD4 down-regulation is adaptor protein complex 2 dependent. J Immunol (2005) 1.09
The sirtuins, oxidative stress and aging: an emerging link. Aging (Albany NY) (2013) 1.08
A single conserved leucine residue on the first intracellular loop regulates ER export of G protein-coupled receptors. Traffic (2009) 1.07
Effect of carcinogenic acrolein on DNA repair and mutagenic susceptibility. J Biol Chem (2012) 1.07
(E)-1-{4-[Bis(4-bromo-phen-yl)meth-yl]piperazin-1-yl}-3-(4-bromo-phen-yl)prop-2-en-1-one. Acta Crystallogr Sect E Struct Rep Online (2011) 1.07
Lexatumumab (TRAIL-receptor 2 mAb) induces expression of DR5 and promotes apoptosis in primary and metastatic renal cell carcinoma in a mouse orthotopic model. Cancer Lett (2006) 1.05
miR-129-3p, as a diagnostic and prognostic biomarker for renal cell carcinoma, attenuates cell migration and invasion via downregulating multiple metastasis-related genes. J Cancer Res Clin Oncol (2014) 1.05
Overexpression of EphA2, MMP-9, and MVD-CD34 in hepatocellular carcinoma: Implications for tumor progression and prognosis. Hepatol Res (2009) 1.05
Discrete signaling pathways participate in RB-dependent responses to chemotherapeutic agents. Oncogene (2004) 1.05
Rab8 interacts with distinct motifs in alpha2B- and beta2-adrenergic receptors and differentially modulates their transport. J Biol Chem (2010) 1.04
ADP-ribosylation factors modulate the cell surface transport of G protein-coupled receptors. J Pharmacol Exp Ther (2010) 1.01
Common genetic risk factors for venous thrombosis in the Chinese population. Am J Hum Genet (2013) 1.01
In vitro panning of a targeting peptide to hepatocarcinoma from a phage display peptide library. Biochem Biophys Res Commun (2006) 1.00
Resveratrol downregulates the constitutional activation of nuclear factor-kappaB in multiple myeloma cells, leading to suppression of proliferation and invasion, arrest of cell cycle, and induction of apoptosis. Cancer Genet Cytogenet (2006) 0.99
Combined antitumor activity of cucurbitacin B and docetaxel in laryngeal cancer. Eur J Pharmacol (2008) 0.99
Surface modifications of nanocarriers for effective intracellular delivery of anti-HIV drugs. Adv Drug Deliv Rev (2009) 0.99
A novel NF-kappaB binding site controls human granzyme B gene transcription. J Immunol (2006) 0.99
Discovery of a highly potent, selective, and bioavailable soluble epoxide hydrolase inhibitor with excellent ex vivo target engagement. J Med Chem (2009) 0.99
Prevalence of human papillomavirus infection in Guangdong Province, China: a population-based survey of 78,355 women. Sex Transm Dis (2014) 0.99
Quantitative analysis of multiple methylated genes in plasma for the diagnosis and prognosis of hepatocellular carcinoma. Exp Mol Pathol (2011) 0.97
NFAT3 is specifically required for TNF-alpha-induced cyclooxygenase-2 (COX-2) expression and transformation of Cl41 cells. J Cell Sci (2006) 0.97
Acrolein induced DNA damage, mutagenicity and effect on DNA repair. Mol Nutr Food Res (2011) 0.97
Involvement of FLIP in 2-methoxyestradiol-induced tumor regression in transgenic adenocarcinoma of mouse prostate model. Clin Cancer Res (2009) 0.97
Long-term antiepileptic drug administration during early life inhibits hippocampal neurogenesis in the developing brain. J Neurosci Res (2009) 0.96
The Shanghai Changfeng Study: a community-based prospective cohort study of chronic diseases among middle-aged and elderly: objectives and design. Eur J Epidemiol (2010) 0.96
Lyn and PECAM-1 function as interdependent inhibitors of platelet aggregation. Blood (2011) 0.95
Targeted constitutive activation of signal transducer and activator of transcription 3 in human hepatocellular carcinoma cells by cucurbitacin B. Cancer Chemother Pharmacol (2008) 0.95
Increased dietary NaCl induces renal medullary PGE2 production and natriuresis via the EP2 receptor. Am J Physiol Renal Physiol (2008) 0.95
MiR-214 inhibits cell growth in hepatocellular carcinoma through suppression of β-catenin. Biochem Biophys Res Commun (2012) 0.95
Self-assembly of a series of extended architectures based on polyoxometalate clusters and silver coordination complexes. Inorg Chem (2005) 0.94
MiR-145 regulates PAK4 via the MAPK pathway and exhibits an antitumor effect in human colon cells. Biochem Biophys Res Commun (2012) 0.94
Discovery of spirocyclic secondary amine-derived tertiary ureas as highly potent, selective and bioavailable soluble epoxide hydrolase inhibitors. Bioorg Med Chem Lett (2009) 0.94
Description of a new species of Myxobolus (Myxozoa: myxobolidae) based on morphological and molecular data. J Parasitol (2008) 0.94
MicroRNA-326 functions as a tumor suppressor in glioma by targeting the Nin one binding protein (NOB1). PLoS One (2013) 0.93
Phosphorylation of tau by death-associated protein kinase 1 antagonizes the kinase-induced cell apoptosis. J Alzheimers Dis (2013) 0.93
Double-stranded DNA homology produces a physical signature. Proc Natl Acad Sci U S A (2010) 0.93
Three-stage enzymatic hydrolysis of steam-exploded corn stover at high substrate concentration. Bioresour Technol (2010) 0.92
Genetic background analysis of protein C deficiency demonstrates a recurrent mutation associated with venous thrombosis in Chinese population. PLoS One (2012) 0.92
Downregulation of microRNA-130a contributes to endothelial progenitor cell dysfunction in diabetic patients via its target Runx3. PLoS One (2013) 0.92
Quantitative methylation analysis of multiple genes using methylation-sensitive restriction enzyme-based quantitative PCR for the detection of hepatocellular carcinoma. Exp Mol Pathol (2011) 0.91
Upregulated microRNA-155 expression in peripheral blood mononuclear cells and fibroblast-like synoviocytes in rheumatoid arthritis. Clin Dev Immunol (2013) 0.91
MiR-146b-5p promotes metastasis and induces epithelial-mesenchymal transition in thyroid cancer by targeting ZNRF3. Cell Physiol Biochem (2015) 0.91
HPV genotypes and associated cervical cytological abnormalities in women from the Pearl River Delta region of Guangdong province, China: a cross-sectional study. BMC Infect Dis (2014) 0.91
Diversity and infectivity of arbuscular mycorrhizal fungi in agricultural soils of the Sichuan Province of mainland China. Mycorrhiza (2008) 0.91
Population pharmacokinetics and exposure-response relationship of enfuvirtide in treatment-experienced human immunodeficiency virus type 1-infected patients. Clin Pharmacol Ther (2005) 0.90
The Fas/Fas ligand death receptor pathway contributes to phenylalanine-induced apoptosis in cortical neurons. PLoS One (2013) 0.90
Specific role of polysorbate 80 coating on the targeting of nanoparticles to the brain. Biomaterials (2004) 0.90
microRNA-200c modulates the epithelial-to-mesenchymal transition in human renal cell carcinoma metastasis. Oncol Rep (2013) 0.90
Ligustrazine attenuates oxidative stress-induced activation of hepatic stellate cells by interrupting platelet-derived growth factor-β receptor-mediated ERK and p38 pathways. Toxicol Appl Pharmacol (2012) 0.90
Rosuvastatin enhances angiogenesis via eNOS-dependent mobilization of endothelial progenitor cells. PLoS One (2013) 0.90
Curcumin attenuates angiogenesis in liver fibrosis and inhibits angiogenic properties of hepatic stellate cells. J Cell Mol Med (2014) 0.90
Isolation and partial characterization of cyclic lipopeptide antibiotics produced by Paenibacillus ehimensis B7. BMC Microbiol (2013) 0.90
Glycated haemoglobin in diagnosis of diabetes mellitus and pre-diabetes among middle-aged and elderly population: Shanghai Changfeng study. Biomed Environ Sci (2013) 0.89
Negative regulation of Nmi on virus-triggered type I IFN production by targeting IRF7. J Immunol (2013) 0.89
Lysine 144, a ubiquitin attachment site in HIV-1 Nef, is required for Nef-mediated CD4 down-regulation. J Immunol (2008) 0.89
Direct evidence for the critical role of NFAT3 in benzo[a]pyrene diol-epoxide-induced cell transformation through mediation of inflammatory cytokine TNF induction in mouse epidermal Cl41 cells. Carcinogenesis (2007) 0.89
Discovery of 3,3-disubstituted piperidine-derived trisubstituted ureas as highly potent soluble epoxide hydrolase inhibitors. Bioorg Med Chem Lett (2009) 0.89
Genotypes and toxin gene profiles of Staphylococcus aureus clinical isolates from China. PLoS One (2011) 0.89
Three-stage hydrolysis to enhance enzymatic saccharification of steam-exploded corn stover. Bioresour Technol (2009) 0.89
Novel association of a PROC variant with ischemic stroke in a Chinese Han population. Hum Genet (2012) 0.88