Published in Lab Invest on July 03, 2006
Animal models of acute lung injury. Am J Physiol Lung Cell Mol Physiol (2008) 6.10
Prevention of LPS-induced acute lung injury in mice by mesenchymal stem cells overexpressing angiopoietin 1. PLoS Med (2007) 3.64
Mechanical ventilation using non-injurious ventilation settings causes lung injury in the absence of pre-existing lung injury in healthy mice. Crit Care (2009) 1.92
Acute kidney injury in critically ill newborns: what do we know? What do we need to learn? Pediatr Nephrol (2008) 1.90
Toll-like receptor 4 mediates neutrophil sequestration and lung injury induced by endotoxin and hyperinflation. Crit Care Med (2010) 1.87
Both high level pressure support ventilation and controlled mechanical ventilation induce diaphragm dysfunction and atrophy. Crit Care Med (2012) 1.87
Nicotinamide exacerbates hypoxemia in ventilator-induced lung injury independent of neutrophil infiltration. PLoS One (2015) 1.39
Simvastatin attenuates ventilator-induced lung injury in mice. Crit Care (2010) 1.34
Role of the pulmonary epithelium and inflammatory signals in acute lung injury. Expert Rev Clin Immunol (2009) 1.10
Integrating microRNAs into a system biology approach to acute lung injury. Transl Res (2011) 1.10
Recent advances and new opportunities in lung mechanobiology. J Biomech (2009) 1.06
A transgenic mouse with vascular endothelial over-expression of the non-muscle myosin light chain kinase-2 isoform is susceptible to inflammatory lung injury: role of sexual dimorphism and age. Transl Res (2008) 1.06
Bench-to-bedside review: Damage-associated molecular patterns in the onset of ventilator-induced lung injury. Crit Care (2011) 0.99
Noninjurious mechanical ventilation activates a proinflammatory transcriptional program in the lung. Physiol Genomics (2009) 0.98
Renal hypoperfusion and impaired endothelium-dependent vasodilation in an animal model of VILI: the role of the peroxynitrite-PARP pathway. Crit Care (2010) 0.98
Of mice and men: comparative proteomics of bronchoalveolar fluid. Eur Respir J (2009) 0.96
The NLRP3 inflammasome is required for the development of hypoxemia in LPS/mechanical ventilation acute lung injury. Am J Respir Cell Mol Biol (2014) 0.95
Mechanical ventilation enhances lung inflammation and caspase activity in a model of mouse pneumovirus infection. Am J Physiol Lung Cell Mol Physiol (2008) 0.94
Mechanical ventilation drives pneumococcal pneumonia into lung injury and sepsis in mice: protection by adrenomedullin. Crit Care (2014) 0.92
Interactions between mechanical and biological processes in acute lung injury. Proc Am Thorac Soc (2008) 0.90
Mechanical ventilation modulates Toll-like receptor-3-induced lung inflammation via a MyD88-dependent, TLR4-independent pathway: a controlled animal study. BMC Pulm Med (2010) 0.90
NF-κB activation in myeloid cells mediates ventilator-induced lung injury. Respir Res (2013) 0.88
Platelets enhance endothelial adhesiveness in high tidal volume ventilation. Am J Respir Cell Mol Biol (2008) 0.87
Intermedin stabilized endothelial barrier function and attenuated ventilator-induced lung injury in mice. PLoS One (2012) 0.86
Role of the Fas/FasL system in a model of RSV infection in mechanically ventilated mice. Am J Physiol Lung Cell Mol Physiol (2011) 0.85
Clara cell protein in bronchoalveolar lavage fluid: a predictor of ventilator-associated pneumonia? Crit Care (2011) 0.84
Experimental acute lung injury induces multi-organ epigenetic modifications in key angiogenic genes implicated in sepsis-associated endothelial dysfunction. Crit Care (2015) 0.83
Cyclic stretch magnitude and duration affect rat alveolar epithelial gene expression. Cell Physiol Biochem (2009) 0.82
Ventilator-induced inflammatory response in lipopolysaccharide-exposed rat lung is mediated by angiotensin-converting enzyme. Am J Pathol (2010) 0.82
SB203580, a p38 inhibitor, improved cardiac function but worsened lung injury and survival during Escherichia coli pneumonia in mice. J Trauma (2010) 0.82
Bench-to-bedside review: Ventilation-induced renal injury through systemic mediator release--just theory or a causal relationship? Crit Care (2011) 0.81
Risk factors for acute organ failure in intensive care unit patients who receive respiratory support in the absence of non-respiratory organ failure: an international prospective cohort study. Crit Care (2012) 0.79
Mitochondrial Targeted Endonuclease III DNA Repair Enzyme Protects against Ventilator Induced Lung Injury in Mice. Pharmaceuticals (Basel) (2014) 0.77
Comparison of pulmonary inflammatory and antioxidant responses to intranasal live and heat-killed Streptococcus pneumoniae in mice. Inflammation (2011) 0.77
Zinc-deficient diet aggravates ventilation-induced lung injury in rats. J Biomed Res (2012) 0.77
Murine mechanical ventilation stimulates alveolar epithelial cell proliferation. Exp Lung Res (2010) 0.76
Variable ventilation improves pulmonary function and reduces lung damage without increasing bacterial translocation in a rat model of experimental pneumonia. Respir Res (2016) 0.75
Pseudomonas aeruginosa Ventilator-Associated Pneumonia Induces Lung Injury through TNF-α/c-Jun NH2-Terminal Kinase Pathways. PLoS One (2017) 0.75
The effects of exogenous surfactant administration on ventilation-induced inflammation in mouse models of lung injury. BMC Pulm Med (2013) 0.75
Animal models of hospital-acquired pneumonia: current practices and future perspectives. Ann Transl Med (2017) 0.75
Tidal volume in animal models of hemorrhagic and endotoxic shock. Exp Ther Med (2013) 0.75
Mechanical Ventilation Alters the Development of Staphylococcus aureus Pneumonia in Rabbit. PLoS One (2016) 0.75
The receptor for advanced glycation end products in ventilator-induced lung injury. Intensive Care Med Exp (2014) 0.75
Pseudomonas aeruginosa colonization enhances ventilator-associated pneumonia-induced lung injury. Respir Res (2016) 0.75
SYSTEM-WIDE MAPPING OF ACTIVATED CIRCUITRY IN EXPERIMENTAL SYSTEMIC INFLAMMATORY RESPONSE SYNDROME. Shock (2016) 0.75
Rapid mobilization of murine and human hematopoietic stem and progenitor cells with AMD3100, a CXCR4 antagonist. J Exp Med (2005) 7.01
Animal models of acute lung injury. Am J Physiol Lung Cell Mol Physiol (2008) 6.10
An official American Thoracic Society workshop report: features and measurements of experimental acute lung injury in animals. Am J Respir Cell Mol Biol (2011) 4.65
Mesenchymal stem cells reduce inflammation while enhancing bacterial clearance and improving survival in sepsis. Am J Respir Crit Care Med (2010) 3.83
Prevention of LPS-induced acute lung injury in mice by mesenchymal stem cells overexpressing angiopoietin 1. PLoS Med (2007) 3.64
Polymorphonuclear leukocytes mediate Staphylococcus aureus Panton-Valentine leukocidin-induced lung inflammation and injury. Proc Natl Acad Sci U S A (2010) 3.05
Stabilized imaging of immune surveillance in the mouse lung. Nat Methods (2010) 2.66
Use of peroxisome proliferator-activated receptor gamma agonists as adjunctive treatment for Plasmodium falciparum malaria: a randomized, double-blind, placebo-controlled trial. Clin Infect Dis (2009) 2.66
Toll-like receptor 1 polymorphisms affect innate immune responses and outcomes in sepsis. Am J Respir Crit Care Med (2008) 2.64
Angiopoietin-1 and angiopoietin-2 as clinically informative prognostic biomarkers of morbidity and mortality in severe sepsis. Crit Care Med (2011) 2.59
Into the eye of the cytokine storm. Microbiol Mol Biol Rev (2012) 2.58
Relationship between cystic fibrosis respiratory tract bacterial communities and age, genotype, antibiotics and Pseudomonas aeruginosa. Environ Microbiol (2010) 2.55
Augmented lung injury due to interaction between hyperoxia and mechanical ventilation. Crit Care Med (2004) 2.29
A phase II randomized placebo-controlled trial of omega-3 fatty acids for the treatment of acute lung injury. Crit Care Med (2011) 2.27
Cellular and molecular abnormalities in severe congenital neutropenia predisposing to leukemia. Exp Hematol (2003) 2.25
The phagocytes: neutrophils and monocytes. Blood (2008) 2.25
The murine CCR3 receptor regulates both the role of eosinophils and mast cells in allergen-induced airway inflammation and hyperresponsiveness. Proc Natl Acad Sci U S A (2002) 2.24
Prognostic and pathogenetic value of combining clinical and biochemical indices in patients with acute lung injury. Chest (2009) 2.17
Essential role of MMP-12 in Fas-induced lung fibrosis. Am J Respir Cell Mol Biol (2007) 2.16
Modulation of lipopolysaccharide-induced gene transcription and promotion of lung injury by mechanical ventilation. J Immunol (2005) 2.05
Serum angiopoietin-1 and -2 levels discriminate cerebral malaria from uncomplicated malaria and predict clinical outcome in African children. PLoS One (2009) 1.93
Granulocyte transfusion therapy for infections in candidates and recipients of HPC transplantation: a comparative analysis of feasibility and outcome for community donors versus related donors. Transfusion (2002) 1.89
Elevation of KL-6, a lung epithelial cell marker, in plasma and epithelial lining fluid in acute respiratory distress syndrome. Am J Physiol Lung Cell Mol Physiol (2003) 1.82
Effects of leukoreduced blood on acute lung injury after trauma: a randomized controlled trial. Crit Care Med (2008) 1.82
Mechanical ventilation with moderate tidal volumes synergistically increases lung cytokine response to systemic endotoxin. Am J Physiol Lung Cell Mol Physiol (2004) 1.81
Role of lung pericytes and resident fibroblasts in the pathogenesis of pulmonary fibrosis. Am J Respir Crit Care Med (2013) 1.67
Spatial distribution of ventilation and perfusion in anesthetized dogs in lateral postures. J Appl Physiol (1985) (2002) 1.66
Identification of high and low responders to lipopolysaccharide in normal subjects: an unbiased approach to identify modulators of innate immunity. J Immunol (2005) 1.66
Duffy antigen facilitates movement of chemokine across the endothelium in vitro and promotes neutrophil transmigration in vitro and in vivo. J Immunol (2003) 1.62
Whole blood angiopoietin-1 and -2 levels discriminate cerebral and severe (non-cerebral) malaria from uncomplicated malaria. Malar J (2009) 1.59
Fas (CD95) induces proinflammatory cytokine responses by human monocytes and monocyte-derived macrophages. J Immunol (2003) 1.57
Combinations of host biomarkers predict mortality among Ugandan children with severe malaria: a retrospective case-control study. PLoS One (2011) 1.55
Apoptosis and epithelial injury in the lungs. Proc Am Thorac Soc (2005) 1.53
Phenazine content in the cystic fibrosis respiratory tract negatively correlates with lung function and microbial complexity. Am J Respir Cell Mol Biol (2012) 1.52
Regulation and function of epithelial secreted phospholipase A2 group X in asthma. Am J Respir Crit Care Med (2013) 1.51
The Duffy antigen modifies systemic and local tissue chemokine responses following lipopolysaccharide stimulation. J Immunol (2006) 1.50
Lung epithelial cell apoptosis during acute lung injury in infancy. Pediatr Crit Care Med (2007) 1.50
Effects of anemia and hypotension on porcine optic nerve blood flow and oxygen delivery. Anesthesiology (2008) 1.49
Patients with COPD with higher levels of anxiety are more physically active. Chest (2013) 1.47
Science review: apoptosis in acute lung injury. Crit Care (2003) 1.45
The role of apoptosis in acute lung injury. Crit Care Med (2003) 1.43
Biomarkers of endothelial activation/dysfunction in infectious diseases. Virulence (2013) 1.42
Pericyte MyD88 and IRAK4 control inflammatory and fibrotic responses to tissue injury. J Clin Invest (2016) 1.39
A porcine model for initial surge mechanical ventilator assessment and evaluation of two limited-function ventilators. Crit Care Med (2011) 1.39
C5 deficiency and C5a or C5aR blockade protects against cerebral malaria. J Exp Med (2008) 1.38
The ethical conduct of clinical research involving critically ill patients in the United States and Canada: principles and recommendations. Am J Respir Crit Care Med (2004) 1.36
Mechanical ventilation affects lung function and cytokine production in an experimental model of endotoxemia. Anesthesiology (2005) 1.34
Optimal timing to repopulation of resident alveolar macrophages with donor cells following total body irradiation and bone marrow transplantation in mice. J Immunol Methods (2004) 1.32
TLR-4 pathway mediates the inflammatory response but not bacterial elimination in E. coli pneumonia. Am J Physiol Lung Cell Mol Physiol (2005) 1.32
Parasite burden and CD36-mediated sequestration are determinants of acute lung injury in an experimental malaria model. PLoS Pathog (2008) 1.28
Differential response of human lung epithelial cells to fas-induced apoptosis. Am J Pathol (2004) 1.27
Mechanical ventilation interacts with endotoxemia to induce extrapulmonary organ dysfunction. Crit Care (2006) 1.25
Differential constitutive and cytokine-modulated expression of human Toll-like receptors in primary neutrophils, monocytes, and macrophages. Int J Med Sci (2008) 1.24
Kinetics of chemokine-glycosaminoglycan interactions control neutrophil migration into the airspaces of the lungs. J Immunol (2010) 1.23
Physiological functions of caspases beyond cell death. Am J Pathol (2006) 1.22
Fas-mediated acute lung injury requires fas expression on nonmyeloid cells of the lung. J Immunol (2005) 1.22
Expression microarray analysis implicates apoptosis and interferon-responsive mechanisms in susceptibility to experimental cerebral malaria. Am J Pathol (2007) 1.20
Simultaneous host and parasite expression profiling identifies tissue-specific transcriptional programs associated with susceptibility or resistance to experimental cerebral malaria. BMC Genomics (2006) 1.20
Genetic variation in the FAS gene and associations with acute lung injury. Am J Respir Crit Care Med (2010) 1.19
The CXCR4/CXCR7/SDF-1 pathway contributes to the pathogenesis of Shiga toxin-associated hemolytic uremic syndrome in humans and mice. J Clin Invest (2012) 1.18
Proteomic and computational analysis of bronchoalveolar proteins during the course of the acute respiratory distress syndrome. Am J Respir Crit Care Med (2008) 1.17
Binding of interleukin-8 to heparan sulfate and chondroitin sulfate in lung tissue. Am J Respir Cell Mol Biol (2003) 1.17
Leukocytosis and Mobilization of CD34+ Hematopoietic Progenitor Cells by AMD3100, a CXCR4 Antagonist. Support Cancer Ther (2004) 1.16
C5a enhances dysregulated inflammatory and angiogenic responses to malaria in vitro: potential implications for placental malaria. PLoS One (2009) 1.16
Computational identification of key biological modules and transcription factors in acute lung injury. Am J Respir Crit Care Med (2005) 1.15
Enhancement of the endotoxin recognition pathway by ventilation with a large tidal volume in rabbits. Am J Physiol Lung Cell Mol Physiol (2003) 1.13
Inflammatory cells as a source of airspace extracellular superoxide dismutase after pulmonary injury. Am J Respir Cell Mol Biol (2005) 1.13
Apoptosis of vascular smooth muscle cells is induced by Fas ligand derived from monocytes/macrophage. Atherosclerosis (2002) 1.12
Endothelial activation, dysfunction and permeability during severe infections. Curr Opin Hematol (2011) 1.11
Differential role of MyD88 in macrophage-mediated responses to opportunistic fungal pathogens. Infect Immun (2003) 1.11
Sustained lipopolysaccharide-induced lung inflammation in mice is attenuated by functional deficiency of the Fas/Fas ligand system. Clin Diagn Lab Immunol (2004) 1.08
Pandemic H1N1 influenza infection and vascular thrombosis. Clin Infect Dis (2011) 1.08
Use of a three-band HRP2/pLDH combination rapid diagnostic test increases diagnostic specificity for falciparum malaria in Ugandan children. Malar J (2014) 1.07
Blockade of the Fas/FasL system improves pneumococcal clearance from the lungs without preventing dissemination of bacteria to the spleen. J Infect Dis (2005) 1.06
Myeloperoxidase inactivates TIMP-1 by oxidizing its N-terminal cysteine residue: an oxidative mechanism for regulating proteolysis during inflammation. J Biol Chem (2007) 1.06
PSGL-1 and mTOR regulate translation of ROCK-1 and physiological functions of macrophages. EMBO J (2007) 1.06