Published in Curr Biol on July 25, 2006
Polo-like kinases: conservation and divergence in their functions and regulation. Nat Rev Mol Cell Biol (2009) 4.09
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Tension-sensitive Plk1 phosphorylation on BubR1 regulates the stability of kinetochore microtubule interactions. Genes Dev (2007) 2.92
Age-associated increase in aneuploidy and changes in gene expression in mouse eggs. Dev Biol (2008) 1.85
Making an effective switch at the kinetochore by phosphorylation and dephosphorylation. Chromosoma (2013) 1.39
The chromosomal passenger complex activates Polo kinase at centromeres. PLoS Biol (2012) 1.33
Transcriptional response to stress in the dynamic chromatin environment of cycling and mitotic cells. Proc Natl Acad Sci U S A (2013) 1.15
Cdk1 and Plk1 mediate a CLASP2 phospho-switch that stabilizes kinetochore-microtubule attachments. J Cell Biol (2012) 1.13
Phosphorylation of the Ndc80 complex protein, HEC1, by Nek2 kinase modulates chromosome alignment and signaling of the spindle assembly checkpoint. Mol Biol Cell (2011) 1.12
Graft-versus-leukemia antigen CML66 elicits coordinated B-cell and T-cell immunity after donor lymphocyte infusion. Clin Cancer Res (2010) 1.09
Understanding cytokinesis failure. Adv Exp Med Biol (2010) 1.06
Autoinhibition and Polo-dependent multisite phosphorylation restrict activity of the histone H3 kinase Haspin to mitosis. Mol Cell (2013) 1.03
BOBBER1 is a noncanonical Arabidopsis small heat shock protein required for both development and thermotolerance. Plant Physiol (2009) 0.99
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CENP-V is required for centromere organization, chromosome alignment and cytokinesis. EMBO J (2008) 0.91
Development and application of in vivo molecular traps reveals that dynein light chain occupancy differentially affects dynein-mediated processes. Proc Natl Acad Sci U S A (2010) 0.89
Aurora B is regulated by acetylation/deacetylation during mitosis in prostate cancer cells. FASEB J (2012) 0.89
NudC is required for interkinetic nuclear migration and neuronal migration during neocortical development. Dev Biol (2011) 0.88
NudC-like protein 2 regulates the LIS1/dynein pathway by stabilizing LIS1 with Hsp90. Proc Natl Acad Sci U S A (2010) 0.86
The nuclear migration protein NUDF/LIS1 forms a complex with NUDC and BNFA at spindle pole bodies. Eukaryot Cell (2008) 0.86
The microtubule-associated protein, NUD-1, exhibits chaperone activity in vitro. Cell Stress Chaperones (2008) 0.85
Plk1 phosphorylates Sgt1 at the kinetochores to promote timely kinetochore-microtubule attachment. Mol Cell Biol (2012) 0.84
Polo-like kinase 1, on the rise from cell cycle regulation to prostate cancer development. Protein Cell (2012) 0.83
Myosin light chain kinases and phosphatase in mitosis and cytokinesis. Arch Biochem Biophys (2011) 0.83
Illumination of mitotic orchestra during cell division: a Polo view. Cell Signal (2010) 0.82
Mechanisms of Chromosome Congression during Mitosis. Biology (Basel) (2017) 0.82
Structural features and chaperone activity of the NudC protein family. J Mol Biol (2011) 0.81
A stringent requirement for Plk1 T210 phosphorylation during K-fiber assembly and chromosome congression. Chromosoma (2012) 0.80
NudC deacetylation regulates mitotic progression. PLoS One (2013) 0.79
Usp16 regulates kinetochore localization of Plk1 to promote proper chromosome alignment in mitosis. J Cell Biol (2015) 0.77
Multiplex imaging and cellular target identification of kinase inhibitors via an affinity-based proteome profiling approach. Sci Rep (2015) 0.77
Chromosome congression is promoted by CENP-Q- and CENP-E-dependent pathways. J Cell Sci (2014) 0.76
EML4 promotes the loading of NUDC to the spindle for mitotic progression. Cell Cycle (2015) 0.75
Dynamic Phosphorylation of NudC by Aurora B in Cytokinesis. PLoS One (2016) 0.75
Decoding Polo-like kinase 1 signaling along the kinetochore-centromere axis. Nat Chem Biol (2016) 0.75
Osteoblasts in prostate cancer metastasis to bone. Nat Rev Cancer (2005) 2.86
SRC-3 is required for prostate cancer cell proliferation and survival. Cancer Res (2005) 2.07
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Androgen receptor-negative human prostate cancer cells induce osteogenesis in mice through FGF9-mediated mechanisms. J Clin Invest (2008) 1.87
Aurora-C kinase supports mitotic progression in the absence of Aurora-B. Cell Cycle (2009) 1.82
Stem-cell origin of metastasis and heterogeneity in solid tumours. Lancet Oncol (2002) 1.74
Cadherin-11 promotes the metastasis of prostate cancer cells to bone. Mol Cancer Res (2008) 1.67
An inducible mouse model for skin cancer reveals distinct roles for gain- and loss-of-function p53 mutations. J Clin Invest (2007) 1.64
Identification of a novel protein, LYRIC, localized to tight junctions of polarized epithelial cells. Exp Cell Res (2004) 1.59
A role for Plk1 phosphorylation of NudC in cytokinesis. Dev Cell (2003) 1.55
Cadherin-11 increases migration and invasion of prostate cancer cells and enhances their interaction with osteoblasts. Cancer Res (2010) 1.46
CXCR2 promotes ovarian cancer growth through dysregulated cell cycle, diminished apoptosis, and enhanced angiogenesis. Clin Cancer Res (2010) 1.42
A novel mechanism of action of methyl-2-cyano-3,12 dioxoolean-1,9 diene-28-oate: direct permeabilization of the inner mitochondrial membrane to inhibit electron transport and induce apoptosis. Mol Pharmacol (2006) 1.41
Stanniocalcin 1 and ovarian tumorigenesis. J Natl Cancer Inst (2010) 1.33
SHP1 phosphatase-dependent T cell inhibition by CEACAM1 adhesion molecule isoforms. Immunity (2006) 1.33
2-Cyano-3,12-dioxooleana-1,9-dien-28-imidazolide (CDDO-Im) directly targets mitochondrial glutathione to induce apoptosis in pancreatic cancer. J Biol Chem (2005) 1.32
Histone deacetylase 3 localizes to the mitotic spindle and is required for kinetochore-microtubule attachment. Proc Natl Acad Sci U S A (2008) 1.30
Forkhead box transcription factor FOXO3a suppresses estrogen-dependent breast cancer cell proliferation and tumorigenesis. Breast Cancer Res (2008) 1.30
SENP1 induces prostatic intraepithelial neoplasia through multiple mechanisms. J Biol Chem (2010) 1.29
BMP4 promotes prostate tumor growth in bone through osteogenesis. Cancer Res (2011) 1.23
Understanding the biology of bone metastases: key to the effective treatment of prostate cancer. Clin Cancer Res (2008) 1.22
Role for NudC, a dynein-associated nuclear movement protein, in mitosis and cytokinesis. J Cell Sci (2003) 1.21
Nuclear receptor COUP-TFII controls pancreatic islet tumor angiogenesis by regulating vascular endothelial growth factor/vascular endothelial growth factor receptor-2 signaling. Cancer Res (2010) 1.19
Molecular classification of prostate cancer progression: foundation for marker-driven treatment of prostate cancer. Cancer Discov (2013) 1.18
A secreted isoform of ErbB3 promotes osteonectin expression in bone and enhances the invasiveness of prostate cancer cells. Cancer Res (2007) 1.07
Nuclear receptor chicken ovalbumin upstream promoter-transcription factor II (COUP-TFII) modulates mesenchymal cell commitment and differentiation. Proc Natl Acad Sci U S A (2011) 1.06
Identification of Sp2 as a transcriptional repressor of carcinoembryonic antigen-related cell adhesion molecule 1 in tumorigenesis. Cancer Res (2004) 1.06
Androgen depletion up-regulates cadherin-11 expression in prostate cancer. J Pathol (2010) 1.04
Biology and clinical management of prostate cancer bone metastasis. Front Biosci (2007) 1.04
Up-regulation of MDA-BF-1, a secreted isoform of ErbB3, in metastatic prostate cancer cells and activated osteoblasts in bone marrow. J Pathol (2004) 1.03
Therapy tolerance in selected patients with androgen-independent prostate cancer following strontium-89 combined with chemotherapy. J Clin Oncol (2005) 1.03
CEACAM1 modulates epidermal growth factor receptor--mediated cell proliferation. J Clin Invest (2004) 1.02
Targeting constitutively activated β1 integrins inhibits prostate cancer metastasis. Mol Cancer Res (2013) 1.01
mNUDC is required for plus-end-directed transport of cytoplasmic dynein and dynactins by kinesin-1. EMBO J (2009) 1.01
Bone microenvironment and androgen status modulate subcellular localization of ErbB3 in prostate cancer cells. Mol Cancer Res (2007) 1.00
16-kDa prolactin inhibits endothelial cell migration by down-regulating the Ras-Tiam1-Rac1-Pak1 signaling pathway. Cancer Res (2007) 1.00
Aurora kinase-A regulates kinetochore/chromatin associated microtubule assembly in human cells. Cell Cycle (2008) 0.99
The central role of osteoblasts in the metastasis of prostate cancer. Cancer Metastasis Rev (2006) 0.99
Hypoxia-inducible factor-2α regulates GM-CSF-derived soluble vascular endothelial growth factor receptor 1 production from macrophages and inhibits tumor growth and angiogenesis. J Immunol (2011) 0.98
Expression of the extracellular domain of OB-cadherin as an Fc fusion protein using bicistronic retroviral expression vector. Protein Expr Purif (2008) 0.96
Prostate cancer stem cells. Clin Genitourin Cancer (2012) 0.96
Loss of let-7 microRNA upregulates IL-6 in bone marrow-derived mesenchymal stem cells triggering a reactive stromal response to prostate cancer. PLoS One (2013) 0.95
Hp95 promotes anoikis and inhibits tumorigenicity of HeLa cells. Oncogene (2002) 0.94
Aurora-C and Aurora-B share phosphorylation and regulation of CENP-A and Borealin during mitosis. Cell Cycle (2008) 0.94
Inhibition of FOXO3 tumor suppressor function by betaTrCP1 through ubiquitin-mediated degradation in a tumor mouse model. PLoS One (2010) 0.93
Acetylation of RNA processing proteins and cell cycle proteins in mitosis. J Proteome Res (2010) 0.93
The HIV-1 p6/EIAV p9 docking site in Alix is autoinhibited as revealed by a conformation-sensitive anti-Alix monoclonal antibody. Biochem J (2008) 0.92
The CHMP4b- and Src-docking sites in the Bro1 domain are autoinhibited in the native state of Alix. Biochem J (2009) 0.92
Caenorhabditis elegans cyclin B3 is required for multiple mitotic processes including alleviation of a spindle checkpoint-dependent block in anaphase chromosome segregation. PLoS Genet (2010) 0.92
Biological significance of c-met over expression in papillary renal cell carcinoma. J Urol (2002) 0.92
Current trials using bone-targeting agents in prostate cancer. Cancer J (2008) 0.91
Lithium chloride attenuates BMP-2 signaling and inhibits osteogenic differentiation through a novel WNT/GSK3- independent mechanism. Bone (2010) 0.90
16K-prolactin inhibits activation of endothelial nitric oxide synthase, intracellular calcium mobilization, and endothelium-dependent vasorelaxation. Endocrinology (2004) 0.90
Vasoinhibins prevent retinal vasopermeability associated with diabetic retinopathy in rats via protein phosphatase 2A-dependent eNOS inactivation. J Clin Invest (2008) 0.89
Expression of recombinant MDA-BF-1 with a kinase recognition site and a 7-histidine tag for receptor binding and purification. Protein Expr Purif (2005) 0.89
Aurora B is regulated by acetylation/deacetylation during mitosis in prostate cancer cells. FASEB J (2012) 0.89
Inhibition of prostate tumor angiogenesis by the tumor suppressor CEACAM1. J Biol Chem (2002) 0.88
Modulation of prostate cancer cell gene expression by cell-to-cell contact with bone marrow stromal cells or osteoblasts. Clin Exp Metastasis (2009) 0.87
Small-molecule protein tyrosine kinase inhibitors for the treatment of metastatic prostate cancer. Future Med Chem (2012) 0.87
Soluble ErbB3 levels in bone marrow and plasma of men with prostate cancer. Clin Cancer Res (2008) 0.87
Extracellular Alix regulates integrin-mediated cell adhesions and extracellular matrix assembly. EMBO J (2008) 0.86
16-kDa prolactin down-regulates inducible nitric oxide synthase expression through inhibition of the signal transducer and activator of transcription 1/IFN regulatory factor-1 pathway. Cancer Res (2005) 0.86
Clinical aspects of bone metastases in prostate cancer. Cancer Treat Res (2004) 0.86
Thrombopoietin-induced CXC chemokines, NAP-2 and PF4, suppress polyploidization and proplatelet formation during megakaryocyte maturation. Genes Cells (2003) 0.84
Antitumor activity of the 16-kDa prolactin fragment in prostate cancer. Cancer Res (2003) 0.84
One-step isolation of plasma membrane proteins using magnetic beads with immobilized concanavalin A. Protein Expr Purif (2008) 0.83
Expression and purification of the angiogenesis inhibitor 16-kDa prolactin fragment from insect cells. Protein Expr Purif (2003) 0.83
Ectopic expression of FGF-3 results in abnormal prostate and Wolffian duct development. Oncogene (2002) 0.83
The germinal center kinase GCK-1 is a negative regulator of MAP kinase activation and apoptosis in the C. elegans germline. PLoS One (2009) 0.82
Osteolytic and osteoblastic bone metastases: two extremes of the same spectrum? Recent Results Cancer Res (2012) 0.82
Multimodality therapy: bone-targeted radioisotope therapy of prostate cancer. Clin Adv Hematol Oncol (2010) 0.82
Metabolic activation of CaMKII by coenzyme A. Mol Cell (2013) 0.82
Dissecting the M phase-specific phosphorylation of serine-proline or threonine-proline motifs. Mol Biol Cell (2010) 0.82
Aberrant expression of katanin p60 in prostate cancer bone metastasis. Prostate (2011) 0.81
Inhibition of prostate tumor growth by overexpression of NudC, a microtubule motor-associated protein. Oncogene (2004) 0.80
Gene selection for oligonucleotide array: an approach using PM probe level data. Bioinformatics (2004) 0.80
Pilot trial of bone-targeted therapy with zoledronate, thalidomide, and interferon-gamma for metastatic renal cell carcinoma. Cancer (2006) 0.80
Metabolic regulation of CaMKII protein and caspases in Xenopus laevis egg extracts. J Biol Chem (2013) 0.80
NudC deacetylation regulates mitotic progression. PLoS One (2013) 0.79
The transcription factor E74-like factor 4 suppresses differentiation of proliferating CD4+ T cells to the Th17 lineage. J Immunol (2013) 0.77
A framework for image-based classification of mitotic cells in asynchronous populations. Assay Drug Dev Technol (2011) 0.77