Published in Curr Biol on July 25, 2006
mRNA localization: gene expression in the spatial dimension. Cell (2009) 5.50
Regulators of the cytoplasmic dynein motor. Nat Rev Mol Cell Biol (2009) 4.05
In vivo imaging of oskar mRNA transport reveals the mechanism of posterior localization. Cell (2008) 2.63
Subcellular mRNA localization in animal cells and why it matters. Science (2009) 2.54
Egalitarian is a selective RNA-binding protein linking mRNA localization signals to the dynein motor. Genes Dev (2009) 2.26
Bicaudal D2, dynein, and kinesin-1 associate with nuclear pore complexes and regulate centrosome and nuclear positioning during mitotic entry. PLoS Biol (2010) 2.07
Polarity and differential inheritance--universal attributes of life? Cell (2008) 1.72
In the right place at the right time: visualizing and understanding mRNA localization. Nat Rev Mol Cell Biol (2014) 1.72
Kinesin and dynein-dynactin at intersecting microtubules: motor density affects dynein function. Biophys J (2008) 1.70
Dynein and kinesin regulate stress-granule and P-body dynamics. J Cell Sci (2009) 1.46
Multiple kinesin motors coordinate cytoplasmic RNA transport on a subpopulation of microtubules in Xenopus oocytes. Dev Cell (2008) 1.45
BICD2, dynactin, and LIS1 cooperate in regulating dynein recruitment to cellular structures. Mol Biol Cell (2012) 1.44
Bicaudal-D binds clathrin heavy chain to promote its transport and augments synaptic vesicle recycling. EMBO J (2010) 1.24
Direct observation of regulated ribonucleoprotein transport across the nurse cell/oocyte boundary. Mol Biol Cell (2007) 1.24
Protein expression redirects vesicular stomatitis virus RNA synthesis to cytoplasmic inclusions. PLoS Pathog (2010) 1.23
Principles and roles of mRNA localization in animal development. Development (2012) 1.23
A'-form RNA helices are required for cytoplasmic mRNA transport in Drosophila. Nat Struct Mol Biol (2010) 1.19
Single-molecule assays reveal that RNA localization signals regulate dynein-dynactin copy number on individual transcript cargoes. Nat Cell Biol (2012) 1.17
BicaudalD actively regulates microtubule motor activity in lipid droplet transport. PLoS One (2008) 1.16
A dual role for actin and microtubule cytoskeleton in the transport of Golgi units from the nurse cells to the oocyte across ring canals. Mol Biol Cell (2008) 1.15
The fungal RNA-binding protein Rrm4 mediates long-distance transport of ubi1 and rho3 mRNAs. EMBO J (2009) 1.10
C. elegans bicd-1, homolog of the Drosophila dynein accessory factor Bicaudal D, regulates the branching of PVD sensory neuron dendrites. Development (2011) 1.03
Multiple Myo4 motors enhance ASH1 mRNA transport in Saccharomyces cerevisiae. J Cell Biol (2010) 1.02
Single-molecule reconstitution of mRNA transport by a class V myosin. Nat Struct Mol Biol (2013) 1.01
Mechanism and Regulation of Cytoplasmic Dynein. Annu Rev Cell Dev Biol (2015) 1.00
Bicaudal-D uses a parallel, homodimeric coiled coil with heterotypic registry to coordinate recruitment of cargos to dynein. Genes Dev (2013) 0.98
Dynactin suppresses the retrograde movement of apically localized mRNA in Drosophila blastoderm embryos. RNA (2007) 0.96
Assembly of mRNA-protein complexes for directional mRNA transport in eukaryotes--an overview. Curr Protein Pept Sci (2012) 0.95
Motility screen identifies Drosophila IGF-II mRNA-binding protein--zipcode-binding protein acting in oogenesis and synaptogenesis. PLoS Genet (2008) 0.95
The influence of dynein processivity control, MAPs, and microtubule ends on directional movement of a localising mRNA. Elife (2014) 0.94
Molecular motors: directing traffic during RNA localization. Crit Rev Biochem Mol Biol (2011) 0.93
Bicaudal-D regulates fragile X mental retardation protein levels, motility, and function during neuronal morphogenesis. Curr Biol (2010) 0.93
Lissencephaly-1 promotes the recruitment of dynein and dynactin to transported mRNAs. J Cell Biol (2013) 0.93
Dynein-dependent transport of nanos RNA in Drosophila sensory neurons requires Rumpelstiltskin and the germ plasm organizer Oskar. J Neurosci (2013) 0.89
Microtubule-dependent mRNA transport in fungi. Eukaryot Cell (2010) 0.89
Directional transport is mediated by a Dynein-dependent step in an RNA localization pathway. PLoS Biol (2013) 0.89
How does an mRNA find its way? Intracellular localisation of transcripts. Semin Cell Dev Biol (2007) 0.88
Conservation of the RNA Transport Machineries and Their Coupling to Translation Control across Eukaryotes. Comp Funct Genomics (2012) 0.88
RNA localization signals: deciphering the message with bioinformatics. Semin Cell Dev Biol (2007) 0.86
Regulation of zipcode binding protein 1 transport dynamics in axons by myosin Va. J Neurosci (2012) 0.86
RNA localization in neurite morphogenesis and synaptic regulation: current evidence and novel approaches. J Comp Physiol A Neuroethol Sens Neural Behav Physiol (2010) 0.85
A targeted gain-of-function screen identifies genes affecting salivary gland morphogenesis/tubulogenesis in Drosophila. Genetics (2008) 0.85
The RNA-binding protein Rrm4 is essential for efficient secretion of endochitinase Cts1. Mol Cell Proteomics (2011) 0.85
Molecular insights into intracellular RNA localization. Int Rev Cell Mol Biol (2013) 0.84
Of social molecules: The interactive assembly of ASH1 mRNA-transport complexes in yeast. RNA Biol (2014) 0.83
Altered dynein-dependent transport in piRNA pathway mutants. Proc Natl Acad Sci U S A (2009) 0.82
Hitchhiking: A Non-Canonical Mode of Microtubule-Based Transport. Trends Cell Biol (2016) 0.80
mRNA localization: assembly of transport complexes and their incorporation into particles. Curr Opin Genet Dev (2011) 0.79
As the fat flies: The dynamic lipid droplets of Drosophila embryos. Biochim Biophys Acta (2015) 0.79
In vivo monitoring of mRNA movement in Drosophila body wall muscle cells reveals the presence of myofiber domains. PLoS One (2009) 0.79
The Drosophila MAST kinase Drop out is required to initiate membrane compartmentalisation during cellularisation and regulates dynein-based transport. Development (2014) 0.77
A physical model reveals the mechanochemistry responsible for dynein's processive motion. Biophys J (2011) 0.77
RNA localization to the Balbiani body in Xenopus oocytes is regulated by the energy state of the cell and is facilitated by kinesin II. RNA (2009) 0.77
bicoid mRNA localises to the Drosophila oocyte anterior by random Dynein-mediated transport and anchoring. Elife (2016) 0.76
A numbers game underpins cytoplasmic mRNA transport. Nat Cell Biol (2012) 0.76
CK2 activates kinesin via induction of a conformational change. Proc Natl Acad Sci U S A (2014) 0.76
Microtubule motors: moving forward on many fronts. F1000 Biol Rep (2009) 0.75
Temporal control of bidirectional lipid-droplet motion in Drosophila depends on the ratio of kinesin-1 and its co-factor Halo. J Cell Sci (2016) 0.75
Crystallographic characterization of the C-terminal coiled-coil region of mouse Bicaudal-D1 (BICD1). Acta Crystallogr F Struct Biol Commun (2014) 0.75
Cytoplasmic dynein functions as a gear in response to load. Nature (2004) 4.74
Consequences of motor copy number on the intracellular transport of kinesin-1-driven lipid droplets. Cell (2008) 4.11
The lipid-droplet proteome reveals that droplets are a protein-storage depot. Curr Biol (2006) 3.93
Ephrin-B2 controls cell motility and adhesion during blood-vessel-wall assembly. Cell (2006) 3.51
Multiple-motor based transport and its regulation by Tau. Proc Natl Acad Sci U S A (2006) 3.35
LIS1 and NudE induce a persistent dynein force-producing state. Cell (2010) 2.88
Molecular motors: strategies to get along. Curr Biol (2004) 2.41
A cytoplasmic dynein tail mutation impairs motor processivity. Nat Cell Biol (2010) 2.20
A comparison of step-detection methods: how well can you do? Biophys J (2007) 2.16
Tracking single particles: a user-friendly quantitative evaluation. Phys Biol (2005) 2.13
Regulation of lipid-droplet transport by the perilipin homolog LSD2. Curr Biol (2005) 2.05
Effective neutrophil chemotaxis is strongly influenced by mean IL-8 concentration. Biochem Biophys Res Commun (2004) 1.83
Stepping, strain gating, and an unexpected force-velocity curve for multiple-motor-based transport. Curr Biol (2008) 1.75
Cell-to-cell heterogeneity in lipid droplets suggests a mechanism to reduce lipotoxicity. Curr Biol (2013) 1.66
Cluster analysis of networks generated through homology: automatic identification of important protein communities involved in cancer metastasis. BMC Bioinformatics (2006) 1.57
Switching between microtubule- and actin-based transport systems in melanophores is controlled by cAMP levels. Curr Biol (2003) 1.54
PKC controls HGF-dependent c-Met traffic, signalling and cell migration. EMBO J (2004) 1.51
Review: biogenesis of the multifunctional lipid droplet: lipids, proteins, and sites. J Cell Biol (2014) 1.45
Intracellular actin-based transport: how far you go depends on how often you switch. Proc Natl Acad Sci U S A (2004) 1.43
Neutrophil migration in opposing chemoattractant gradients using microfluidic chemotaxis devices. Ann Biomed Eng (2005) 1.41
Intermediate-affinity LFA-1 binds alpha-actinin-1 to control migration at the leading edge of the T cell. EMBO J (2007) 1.39
Localization of DNA polymerases eta and iota to the replication machinery is tightly co-ordinated in human cells. EMBO J (2002) 1.36
Caveolin-1 deficiency causes cholesterol-dependent mitochondrial dysfunction and apoptotic susceptibility. Curr Biol (2011) 1.31
Adenovirus transport via direct interaction of cytoplasmic dynein with the viral capsid hexon subunit. Cell Host Microbe (2009) 1.30
Localization of DNA polymerases eta and iota to the replication machinery is tightly co-ordinated in human cells. EMBO J (2003) 1.29
Tuning microtubule-based transport through filamentous MAPs: the problem of dynein. Traffic (2008) 1.29
Cdc42 and Rac family GTPases regulate mode and speed but not direction of primary fibroblast migration during platelet-derived growth factor-dependent chemotaxis. Mol Cell Biol (2009) 1.29
Ice-water immersion and delayed-onset muscle soreness: a randomised controlled trial. Br J Sports Med (2007) 1.28
Mechanical stochastic tug-of-war models cannot explain bidirectional lipid-droplet transport. Proc Natl Acad Sci U S A (2011) 1.26
The Herpesvirus capsid surface protein, VP26, and the majority of the tegument proteins are dispensable for capsid transport toward the nucleus. J Virol (2006) 1.23
Hydrophobic and basic domains target proteins to lipid droplets. Traffic (2009) 1.22
The Drosophila hairy RNA localization signal modulates the kinetics of cytoplasmic mRNA transport. EMBO J (2003) 1.21
Spatially distinct binding of Cdc42 to PAK1 and N-WASP in breast carcinoma cells. Mol Cell Biol (2005) 1.21
High-resolution imaging reveals indirect coordination of opposite motors and a role for LIS1 in high-load axonal transport. J Cell Biol (2011) 1.19
BicaudalD actively regulates microtubule motor activity in lipid droplet transport. PLoS One (2008) 1.16
Protein kinase C controls microtubule-based traffic but not proteasomal degradation of c-Met. J Biol Chem (2003) 1.13
Restoration of podosomes and chemotaxis in Wiskott-Aldrich syndrome macrophages following induced expression of WASp. Int J Biochem Cell Biol (2002) 1.12
Acyl-CoA synthetase 3 promotes lipid droplet biogenesis in ER microdomains. J Cell Biol (2013) 1.11
Elimination of plasma membrane phosphatidylinositol (4,5)-bisphosphate is required for exocytosis from mast cells. J Cell Sci (2006) 1.10
The importance of lattice defects in katanin-mediated microtubule severing in vitro. Biophys J (2002) 1.07
A novel role for lipid droplets in the organismal antibacterial response. Elife (2012) 1.06
Monte Carlo modeling of single-molecule cytoplasmic dynein. Proc Natl Acad Sci U S A (2005) 1.05
The class II phosphoinositide 3-kinase PI3K-C2beta regulates cell migration by a PtdIns3P dependent mechanism. J Cell Physiol (2005) 1.02
Tuning multiple motor travel via single motor velocity. Traffic (2012) 1.01
Comprehensive structural model of the mechanochemical cycle of a mitotic motor highlights molecular adaptations in the kinesin family. Proc Natl Acad Sci U S A (2014) 1.00
How molecular motors are arranged on a cargo is important for vesicular transport. PLoS Comput Biol (2011) 0.97
Studying molecular motor-based cargo transport: what is real and what is noise? Biophys J (2007) 0.97
Evidence for protein 4.1B acting as a metastasis suppressor. J Cell Sci (2007) 0.94
Connexin interaction patterns in keratinocytes revealed morphologically and by FRET analysis. J Cell Sci (2005) 0.93
Casein kinase 2 reverses tail-independent inactivation of kinesin-1. Nat Commun (2012) 0.92
Improved network community structure improves function prediction. Sci Rep (2013) 0.91
Regulation of lymphatic-blood vessel separation by endothelial Rac1. Development (2009) 0.91
Differential protein partitioning within the herpesvirus tegument and envelope underlies a complex and variable virion architecture. Proc Natl Acad Sci U S A (2013) 0.89
Defective trafficking and cell death is characteristic of skin disease-associated connexin 31 mutations. Hum Mol Genet (2002) 0.88
Mitochondrial cholesterol: a connection between caveolin, metabolism, and disease. Traffic (2011) 0.87
EKV mutant connexin 31 associated cell death is mediated by ER stress. Hum Mol Genet (2009) 0.86
On the use of in vivo cargo velocity as a biophysical marker. Biochem Biophys Res Commun (2006) 0.84
Novel automated tracking analysis of particles subjected to shear flow: kindlin-3 role in B cells. Biophys J (2013) 0.83
Modularity optimization by conformational space annealing. Phys Rev E Stat Nonlin Soft Matter Phys (2012) 0.83
A biophysical analysis of mitochondrial movement: differences between transport in neuronal cell bodies versus processes. Traffic (2014) 0.82
Intracellular transport: how do motors work together? Curr Biol (2009) 0.82
Filament-filament switching can be regulated by separation between filaments together with cargo motor number. PLoS One (2013) 0.81
Biophysical characterization of an integrin-targeted lipopolyplex gene delivery vector. Biochemistry (2007) 0.80
Inhibition of invasion and induction of apoptosis by selenium in human malignant brain tumour cells in vitro. Int J Oncol (2007) 0.78
Fluorescence localization after photobleaching (FLAP). Curr Protoc Cell Biol (2004) 0.77
Isolation and purification of kinesin from Drosophila embryos. J Vis Exp (2012) 0.77
Killing of Kras-mutant colon cancer cells via Rac-independent actin remodeling by the βGBP cytokine, a physiological PI3K inhibitor therapeutically effective in vivo. Mol Cancer Ther (2012) 0.75
Use of oral corticosteroids in sports medicine. Curr Sports Med Rep (2004) 0.75
Novel shear flow assay provides evidence for non-linear modulation of cancer invasion. Front Biosci (Landmark Ed) (2009) 0.75