Published in Front Biosci (Landmark Ed) on January 01, 2009
A community-driven global reconstruction of human metabolism. Nat Biotechnol (2013) 3.89
Ephrin-B2 controls cell motility and adhesion during blood-vessel-wall assembly. Cell (2006) 3.51
HepatoNet1: a comprehensive metabolic reconstruction of the human hepatocyte for the analysis of liver physiology. Mol Syst Biol (2010) 2.05
Guidance of bidirectional motor complexes by mRNA cargoes through control of dynein number and activity. Curr Biol (2006) 1.74
Intravital imaging reveals transient changes in pigment production and Brn2 expression during metastatic melanoma dissemination. Cancer Res (2009) 1.63
Cluster analysis of networks generated through homology: automatic identification of important protein communities involved in cancer metastasis. BMC Bioinformatics (2006) 1.57
PKC controls HGF-dependent c-Met traffic, signalling and cell migration. EMBO J (2004) 1.51
Differential proliferation rates generate patterns of mechanical tension that orient tissue growth. EMBO J (2013) 1.49
Tumor-related alternatively spliced Rac1b is not regulated by Rho-GDP dissociation inhibitors and exhibits selective downstream signaling. J Biol Chem (2003) 1.39
Intermediate-affinity LFA-1 binds alpha-actinin-1 to control migration at the leading edge of the T cell. EMBO J (2007) 1.39
Localization of DNA polymerases eta and iota to the replication machinery is tightly co-ordinated in human cells. EMBO J (2002) 1.36
An ensemble classification-based approach applied to retinal blood vessel segmentation. IEEE Trans Biomed Eng (2012) 1.34
Superimpose: a 3D structural superposition server. Nucleic Acids Res (2008) 1.31
Localization of DNA polymerases eta and iota to the replication machinery is tightly co-ordinated in human cells. EMBO J (2003) 1.29
Cdc42 and Rac family GTPases regulate mode and speed but not direction of primary fibroblast migration during platelet-derived growth factor-dependent chemotaxis. Mol Cell Biol (2009) 1.29
The Drosophila hairy RNA localization signal modulates the kinetics of cytoplasmic mRNA transport. EMBO J (2003) 1.21
Spatially distinct binding of Cdc42 to PAK1 and N-WASP in breast carcinoma cells. Mol Cell Biol (2005) 1.21
Antimalarial drug targets in Plasmodium falciparum predicted by stage-specific metabolic network analysis. BMC Syst Biol (2010) 1.19
Antagonistic SR proteins regulate alternative splicing of tumor-related Rac1b downstream of the PI3-kinase and Wnt pathways. Hum Mol Genet (2009) 1.19
Docking without docking: ISEARCH--prediction of interactions using known interfaces. Proteins (2007) 1.17
Protein kinase C controls microtubule-based traffic but not proteasomal degradation of c-Met. J Biol Chem (2003) 1.13
Restoration of podosomes and chemotaxis in Wiskott-Aldrich syndrome macrophages following induced expression of WASp. Int J Biochem Cell Biol (2002) 1.12
Elimination of plasma membrane phosphatidylinositol (4,5)-bisphosphate is required for exocytosis from mast cells. J Cell Sci (2006) 1.10
B-Raf(V600E) cooperates with alternative spliced Rac1b to sustain colorectal cancer cell survival. Gastroenterology (2008) 1.08
Emerging roles for WNK kinases in cancer. Cell Mol Life Sci (2010) 1.07
The class II phosphoinositide 3-kinase PI3K-C2beta regulates cell migration by a PtdIns3P dependent mechanism. J Cell Physiol (2005) 1.02
Expression of Rac1b stimulates NF-kappaB-mediated cell survival and G1/S progression. Exp Cell Res (2005) 1.02
The beta-catenin/TCF4 pathway modifies alternative splicing through modulation of SRp20 expression. RNA (2008) 1.00
Analysis of skin wound images using digital color image processing: a preliminary communication. Int J Low Extrem Wounds (2004) 0.99
Increased Rac1b expression sustains colorectal tumor cell survival. Mol Cancer Res (2008) 0.99
Rac1 signaling modulates BCL-6-mediated repression of gene transcription. Mol Cell Biol (2009) 0.96
Evolutionary approaches to cultural and linguistic diversity. Philos Trans R Soc Lond B Biol Sci (2010) 0.95
Evidence for protein 4.1B acting as a metastasis suppressor. J Cell Sci (2007) 0.94
Loss of WNK2 expression by promoter gene methylation occurs in adult gliomas and triggers Rac1-mediated tumour cell invasiveness. Hum Mol Genet (2012) 0.94
Rac1, but not Rac1B, stimulates RelB-mediated gene transcription in colorectal cancer cells. J Biol Chem (2006) 0.93
Connexin interaction patterns in keratinocytes revealed morphologically and by FRET analysis. J Cell Sci (2005) 0.93
Quantification of left ventricular indices from SSFP cine imaging: impact of real-world variability in analysis methodology and utility of geometric modeling. J Magn Reson Imaging (2012) 0.91
Regulation of lymphatic-blood vessel separation by endothelial Rac1. Development (2009) 0.91
Phosphorylation of SRSF1 by SRPK1 regulates alternative splicing of tumor-related Rac1b in colorectal cells. RNA (2014) 0.90
Defective trafficking and cell death is characteristic of skin disease-associated connexin 31 mutations. Hum Mol Genet (2002) 0.88
WNK2 modulates MEK1 activity through the Rho GTPase pathway. Cell Signal (2008) 0.87
Contribution of casein kinase 2 and spleen tyrosine kinase to CFTR trafficking and protein kinase A-induced activity. Mol Cell Biol (2011) 0.87
IGERS: inferring Gibbs energy changes of biochemical reactions from reaction similarities. Biophys J (2010) 0.87
Mixed lineage kinase 3 gene mutations in mismatch repair deficient gastrointestinal tumours. Hum Mol Genet (2009) 0.86
Network-based assessment of the selectivity of metabolic drug targets in Plasmodium falciparum with respect to human liver metabolism. BMC Syst Biol (2012) 0.86
Transcription initiation arising from E-cadherin/CDH1 intron2: a novel protein isoform that increases gastric cancer cell invasion and angiogenesis. Hum Mol Genet (2012) 0.86
EKV mutant connexin 31 associated cell death is mediated by ER stress. Hum Mol Genet (2009) 0.86
A missense mutation in the APC tumor suppressor gene disrupts an ASF/SF2 splicing enhancer motif and causes pathogenic skipping of exon 14. Mutat Res (2008) 0.84
Pruning genome-scale metabolic models to consistent ad functionem networks. Genome Inform (2007) 0.83
Comparative study of the cytotoxic effect of microcistin-LR and purified extracts from Microcystis aeruginosa on a kidney cell line. Toxicon (2009) 0.83
Novel automated tracking analysis of particles subjected to shear flow: kindlin-3 role in B cells. Biophys J (2013) 0.83
Rac1 signalling modulates a STAT5/BCL-6 transcriptional switch on cell-cycle-associated target gene promoters. Nucleic Acids Res (2012) 0.82
Ibuprofen inhibits colitis-induced overexpression of tumor-related Rac1b. Neoplasia (2013) 0.81
Metannogen: annotation of biological reaction networks. Bioinformatics (2011) 0.80
Evaluation of a domestic violence intervention in the maternity and sexual health services of a UK hospital. Reprod Health Matters (2010) 0.80
Composition of metabolic flux distributions by functionally interpretable minimal flux modes (MinModes). Genome Inform (2006) 0.80
Biophysical characterization of an integrin-targeted lipopolyplex gene delivery vector. Biochemistry (2007) 0.80
Antagonistic regulation of cystic fibrosis transmembrane conductance regulator cell surface expression by protein kinases WNK4 and spleen tyrosine kinase. Mol Cell Biol (2011) 0.80
Unmasking the role of KRAS and BRAF pathways in MSI colorectal tumors. Expert Rev Gastroenterol Hepatol (2009) 0.80
Comparison of real-time three-dimensional echocardiography with cardiovascular magnetic resonance for left ventricular volumetric assessment in unselected patients. Eur Heart J Cardiovasc Imaging (2011) 0.79
Mucosal vaccination against tuberculosis using inert bioparticles. Infect Immun (2013) 0.79
A WNK4 gene variant relates to osteoporosis and not to hypertension in the Portuguese population. Mol Genet Metab (2010) 0.78
Inhibition of invasion and induction of apoptosis by selenium in human malignant brain tumour cells in vitro. Int J Oncol (2007) 0.78
Fluorescence localization after photobleaching (FLAP). Curr Protoc Cell Biol (2004) 0.77
Protein kinase WNK1 promotes cell surface expression of glucose transporter GLUT1 by regulating a Tre-2/USP6-BUB2-Cdc16 domain family member 4 (TBC1D4)-Rab8A complex. J Biol Chem (2010) 0.77
Three-way translocation (X;20;16)(p11;q13;q23) in essential thrombocythemia implicates NFATC2 in dysregulation of CSF2 expression and megakaryocyte proliferation. Genes Chromosomes Cancer (2012) 0.76
The regulation of trophoblast migration across endothelial cells by low shear stress: consequences for vascular remodelling in pregnancy. Cardiovasc Res (2011) 0.76
Combined molecular diagnosis of B-cell lymphomas with t(11;14)(q13;q32) or t(14;18)(q32;q21) using multiplex- and long distance inverse-polymerase chain reaction. Diagn Mol Pathol (2008) 0.76
Killing of Kras-mutant colon cancer cells via Rac-independent actin remodeling by the βGBP cytokine, a physiological PI3K inhibitor therapeutically effective in vivo. Mol Cancer Ther (2012) 0.75
Web-links as a means to document annotated sequence and 3D-structure alignments in systems biology. Genome Inform (2008) 0.75
Corrigendum: Phosphorylation of SRSF1 by SRPK1 regulates alternative splicing of tumor-related Rac1b in colorectal cells. RNA (2016) 0.75
The William Parks exhibition denture--a hidden gem. Dent Hist (2014) 0.75
Three-way translocation involves MLL, MLLT3, and a novel cell cycle control gene, FLJ10374, in the pathogenesis of acute myeloid leukemia with t(9;11;19)(p22;q23;p13.3). Genes Chromosomes Cancer (2006) 0.75