Published in J Biol Chem on July 25, 2006
NHE3 inhibition by cAMP and Ca2+ is abolished in PDZ-domain protein PDZK1-deficient murine enterocytes. J Physiol (2007) 1.20
Role of the adaptor protein PDZK1 in controlling the HDL receptor SR-BI. Curr Opin Lipidol (2009) 1.18
Cellular cholesterol delivery, intracellular processing and utilization for biosynthesis of steroid hormones. Nutr Metab (Lond) (2010) 1.18
Thrombocytopenia and platelet abnormalities in high-density lipoprotein receptor-deficient mice. Arterioscler Thromb Vasc Biol (2008) 1.08
Influence of PDZK1 on lipoprotein metabolism and atherosclerosis. Biochim Biophys Acta (2008) 1.03
Overexpression of the PDZ1 domain of PDZK1 blocks the activity of hepatic scavenger receptor, class B, type I by altering its abundance and cellular localization. J Biol Chem (2008) 1.02
Normal hepatic cell surface localization of the high density lipoprotein receptor, scavenger receptor class B, type I, depends on all four PDZ domains of PDZK1. J Biol Chem (2008) 1.00
The SR-BI partner PDZK1 facilitates hepatitis C virus entry. PLoS Pathog (2010) 0.89
Sensing of dietary lipids by enterocytes: a new role for SR-BI/CLA-1. PLoS One (2009) 0.86
In vitro and in vivo analysis of the binding of the C terminus of the HDL receptor scavenger receptor class B, type I (SR-BI), to the PDZ1 domain of its adaptor protein PDZK1. J Biol Chem (2010) 0.85
Lipid abnormalities in alpha/beta2-syntrophin null mice are independent from ABCA1. Biochim Biophys Acta (2015) 0.84
Identification of the PDZ3 domain of the adaptor protein PDZK1 as a second, physiologically functional binding site for the C terminus of the high density lipoprotein receptor scavenger receptor class B type I. J Biol Chem (2011) 0.84
HDL signaling and protection against coronary artery atherosclerosis in mice. J Biomed Res (2015) 0.79
Noncanonical role of the PDZ4 domain of the adaptor protein PDZK1 in the regulation of the hepatic high density lipoprotein receptor scavenger receptor class B, type I (SR-BI). J Biol Chem (2013) 0.79
Challenges in using cultured primary rodent hepatocytes or cell lines to study hepatic HDL receptor SR-BI regulation by its cytoplasmic adaptor PDZK1. PLoS One (2013) 0.79
Modulators of Protein Kinase C Affect SR-BI-Dependent HDL Lipid Uptake in Transfected HepG2 Cells. Cholesterol (2011) 0.78
Protein mediators of sterol transport across intestinal brush border membrane. Subcell Biochem (2010) 0.76
Carboxy-terminal deletion of the HDL receptor reduces receptor levels in liver and steroidogenic tissues, induces hypercholesterolemia, and causes fatal heart disease. Am J Physiol Heart Circ Physiol (2016) 0.75
SR-BI: A Multifunctional Receptor in Cholesterol Homeostasis and Atherosclerosis. Trends Endocrinol Metab (2017) 0.75
EGFR mutation and resistance of non-small-cell lung cancer to gefitinib. N Engl J Med (2005) 26.35
SIRT1 deacetylates and positively regulates the nuclear receptor LXR. Mol Cell (2007) 5.01
Mutation of the COG complex subunit gene COG7 causes a lethal congenital disorder. Nat Med (2004) 3.06
Role of apoA-I, ABCA1, LCAT, and SR-BI in the biogenesis of HDL. J Mol Med (Berl) (2006) 2.57
Genetic analysis of the subunit organization and function of the conserved oligomeric golgi (COG) complex: studies of COG5- and COG7-deficient mammalian cells. J Biol Chem (2005) 2.53
The role of the high-density lipoprotein receptor SR-BI in the lipid metabolism of endocrine and other tissues. Endocr Rev (2003) 2.47
Loss of cardiac microRNA-mediated regulation leads to dilated cardiomyopathy and heart failure. Circ Res (2009) 2.44
Scavenger receptor class B type I-mediated protection against atherosclerosis in LDL receptor-negative mice involves its expression in bone marrow-derived cells. Arterioscler Thromb Vasc Biol (2003) 2.38
In vivo generation of transplantable human hematopoietic cells from induced pluripotent stem cells. Blood (2012) 2.12
Characterization of a mammalian Golgi-localized protein complex, COG, that is required for normal Golgi morphology and function. J Cell Biol (2002) 2.03
Diet-induced occlusive coronary atherosclerosis, myocardial infarction, cardiac dysfunction, and premature death in scavenger receptor class B type I-deficient, hypomorphic apolipoprotein ER61 mice. Circulation (2005) 1.86
Effects of hepatic expression of the high-density lipoprotein receptor SR-BI on lipoprotein metabolism and female fertility. Endocrinology (2006) 1.83
Non-alcoholic fatty liver disease and its association with obesity, insulin resistance and increased serum levels of C-reactive protein in Hispanics. Liver Int (2008) 1.71
Organization of lin genes and IS6100 among different strains of hexachlorocyclohexane-degrading Sphingomonas paucimobilis: evidence for horizontal gene transfer. J Bacteriol (2004) 1.71
Discovery of chemical inhibitors of the selective transfer of lipids mediated by the HDL receptor SR-BI. Proc Natl Acad Sci U S A (2002) 1.67
Blood markers for vasculogenesis increase with tumor progression in patients with breast carcinoma. Cancer Biol Ther (2003) 1.60
Targeted disruption of the PDZK1 gene in mice causes tissue-specific depletion of the high density lipoprotein receptor scavenger receptor class B type I and altered lipoprotein metabolism. J Biol Chem (2003) 1.56
Conserved oligomeric Golgi complex subunit 1 deficiency reveals a previously uncharacterized congenital disorder of glycosylation type II. Proc Natl Acad Sci U S A (2006) 1.56
Down-regulation and antiproliferative role of C/EBPalpha in lung cancer. Cancer Res (2002) 1.53
Retrograde transport on the COG railway. Trends Cell Biol (2006) 1.53
Identification of apolipoprotein D as a cardioprotective gene using a mouse model of lethal atherosclerotic coronary artery disease. Proc Natl Acad Sci U S A (2013) 1.48
Influence of the HDL receptor SR-BI on lipoprotein metabolism and atherosclerosis. Arterioscler Thromb Vasc Biol (2003) 1.46
The COG and COPI complexes interact to control the abundance of GEARs, a subset of Golgi integral membrane proteins. Mol Biol Cell (2004) 1.45
A new inborn error of glycosylation due to a Cog8 deficiency reveals a critical role for the Cog1-Cog8 interaction in COG complex formation. Hum Mol Genet (2007) 1.40
Subunit architecture of the conserved oligomeric Golgi complex. J Biol Chem (2005) 1.39
Failure of red blood cell maturation in mice with defects in the high-density lipoprotein receptor SR-BI. Blood (2002) 1.37
Relevance of Niemann-Pick type C1 protein expression in controlling plasma cholesterol and biliary lipid secretion in mice. Hepatology (2002) 1.35
Probucol prevents early coronary heart disease and death in the high-density lipoprotein receptor SR-BI/apolipoprotein E double knockout mouse. Proc Natl Acad Sci U S A (2003) 1.33
A dynamic expression survey identifies transcription factors relevant in mouse digestive tract development. Development (2006) 1.32
Diversity, distribution and divergence of lin genes in hexachlorocyclohexane-degrading sphingomonads. Trends Biotechnol (2006) 1.31
Targeted disruption of the PDZK1 gene by homologous recombination. Mol Cell Biol (2003) 1.30
Differential roles of NHERF1, NHERF2, and PDZK1 in regulating CFTR-mediated intestinal anion secretion in mice. J Clin Invest (2009) 1.30
Cytomegalovirus infection causes an increase of arterial blood pressure. PLoS Pathog (2009) 1.25
Gallbladder disease is associated with insulin resistance in a high risk Hispanic population. J Hepatol (2006) 1.24
Respiratory failure due to differentiation arrest and expansion of alveolar cells following lung-specific loss of the transcription factor C/EBPalpha in mice. Mol Cell Biol (2006) 1.21
Alpha-tocopherol metabolism is abnormal in scavenger receptor class B type I (SR-BI)-deficient mice. J Nutr (2002) 1.21
NHE3 inhibition by cAMP and Ca2+ is abolished in PDZ-domain protein PDZK1-deficient murine enterocytes. J Physiol (2007) 1.20
Role of the adaptor protein PDZK1 in controlling the HDL receptor SR-BI. Curr Opin Lipidol (2009) 1.18
Cross-inhibition of SR-BI- and ABCA1-mediated cholesterol transport by the small molecules BLT-4 and glyburide. J Lipid Res (2004) 1.15
Peroxiredoxin1 prevents excessive endothelial activation and early atherosclerosis. Circ Res (2008) 1.14
Increased expression of syndecan-1 protects against cardiac dilatation and dysfunction after myocardial infarction. Circulation (2007) 1.13
Structural integrity of the Golgi is temperature sensitive in conditional-lethal mutants with no detectable GM130. Traffic (2003) 1.12
Fibrates down-regulate hepatic scavenger receptor class B type I protein expression in mice. J Biol Chem (2003) 1.10
Role of PDZK1 in membrane expression of renal brush border ion exchangers. Proc Natl Acad Sci U S A (2005) 1.08
Thrombocytopenia and platelet abnormalities in high-density lipoprotein receptor-deficient mice. Arterioscler Thromb Vasc Biol (2008) 1.08
Expression and regulation of the renal Na/phosphate cotransporter NaPi-IIa in a mouse model deficient for the PDZ protein PDZK1. Pflugers Arch (2004) 1.08
The oxysterol-CXCR2 axis plays a key role in the recruitment of tumor-promoting neutrophils. J Exp Med (2013) 1.06
Down regulation of small intestinal ion transport in PDZK1- (CAP70/NHERF3) deficient mice. Pflugers Arch (2007) 1.06
Endocytosis is not required for the selective lipid uptake mediated by murine SR-BI. Biochim Biophys Acta (2005) 1.05
Analysis of 15 novel full-length BK virus sequences from three individuals: evidence of a high intra-strain genetic diversity. J Gen Virol (2004) 1.05
Elevated levels of soluble P-selectin in mice alter blood-brain barrier function, exacerbate stroke, and promote atherosclerosis. Blood (2009) 1.05
Identification of the N-linked glycosylation sites on the high density lipoprotein (HDL) receptor SR-BI and assessment of their effects on HDL binding and selective lipid uptake. J Biol Chem (2002) 1.04
Multi-component protein complexes and Golgi membrane trafficking. J Biochem (2005) 1.03
Regulation of SR-BI-mediated high-density lipoprotein metabolism by the tissue-specific adaptor protein PDZK1. Curr Opin Lipidol (2005) 1.03
Influence of PDZK1 on lipoprotein metabolism and atherosclerosis. Biochim Biophys Acta (2008) 1.03
Overexpression of the PDZ1 domain of PDZK1 blocks the activity of hepatic scavenger receptor, class B, type I by altering its abundance and cellular localization. J Biol Chem (2008) 1.02
Glycine dimerization motif in the N-terminal transmembrane domain of the high density lipoprotein receptor SR-BI required for normal receptor oligomerization and lipid transport. J Biol Chem (2011) 1.02
Extrahepatic high-density lipoprotein receptor SR-BI and apoA-I protect against deep vein thrombosis in mice. Arterioscler Thromb Vasc Biol (2012) 1.01
Highly purified scavenger receptor class B, type I reconstituted into phosphatidylcholine/cholesterol liposomes mediates high affinity high density lipoprotein binding and selective lipid uptake. J Biol Chem (2002) 1.01
Mice long-term high-fat diet feeding recapitulates human cardiovascular alterations: an animal model to study the early phases of diabetic cardiomyopathy. PLoS One (2013) 1.01
Exoplasmic cysteine Cys384 of the HDL receptor SR-BI is critical for its sensitivity to a small-molecule inhibitor and normal lipid transport activity. Proc Natl Acad Sci U S A (2011) 1.01
Normal hepatic cell surface localization of the high density lipoprotein receptor, scavenger receptor class B, type I, depends on all four PDZ domains of PDZK1. J Biol Chem (2008) 1.00
O-glycosylation regulates ubiquitination and degradation of the anti-inflammatory protein A20 to accelerate atherosclerosis in diabetic ApoE-null mice. PLoS One (2010) 1.00
Insulin restores gestational diabetes mellitus-reduced adenosine transport involving differential expression of insulin receptor isoforms in human umbilical vein endothelium. Diabetes (2011) 0.99
CARM1 is required for proper control of proliferation and differentiation of pulmonary epithelial cells. Development (2010) 0.99
IntraGolgi distribution of the Conserved Oligomeric Golgi (COG) complex. Exp Cell Res (2006) 0.98
NPC2 is expressed in human and murine liver and secreted into bile: potential implications for body cholesterol homeostasis. Hepatology (2006) 0.97
SR-BI mediates cholesterol efflux via its interactions with lipid-bound ApoE. Structural mutations in SR-BI diminish cholesterol efflux. Biochemistry (2005) 0.97
Hepatic cholesterol transport from plasma into bile: implications for gallstone disease. Curr Opin Lipidol (2004) 0.96
Loss of PDZK1 causes coronary artery occlusion and myocardial infarction in Paigen diet-fed apolipoprotein E deficient mice. PLoS One (2009) 0.96
Mediators of galactose sensitivity in UDP-galactose 4'-epimerase-impaired mammalian cells. J Biol Chem (2005) 0.96
Insulin-stimulated L-arginine transport requires SLC7A1 gene expression and is associated with human umbilical vein relaxation. J Cell Physiol (2011) 0.95
Cholesterol depletion induces PKA-mediated basolateral-to-apical transcytosis of the scavenger receptor class B type I in MDCK cells. Proc Natl Acad Sci U S A (2004) 0.95
Cholecystectomy increases hepatic triglyceride content and very-low-density lipoproteins production in mice. Liver Int (2010) 0.94
Hepatic overexpression of caveolins increases bile salt secretion in mice. Hepatology (2003) 0.94
Identification of the molecular target of small molecule inhibitors of HDL receptor SR-BI activity. Biochemistry (2007) 0.93
Standardizing scavenger receptor nomenclature. J Immunol (2014) 0.93
Age-related influence of the HDL receptor SR-BI on synaptic plasticity and cognition. Neurobiol Aging (2007) 0.93