Published in J Bone Miner Res on August 01, 2006
The amazing osteocyte. J Bone Miner Res (2011) 5.32
Osteocyte Wnt/beta-catenin signaling is required for normal bone homeostasis. Mol Cell Biol (2010) 2.85
The osteocyte: an endocrine cell ... and more. Endocr Rev (2013) 1.84
Functional adaptation to mechanical loading in both cortical and cancellous bone is controlled locally and is confined to the loaded bones. Bone (2009) 1.70
Mechanical signaling for bone modeling and remodeling. Crit Rev Eukaryot Gene Expr (2009) 1.33
Osteocyte apoptosis and control of bone resorption following ovariectomy in mice. Bone (2009) 1.30
Sex steroid actions in male bone. Endocr Rev (2014) 1.26
The mouse fibula as a suitable bone for the study of functional adaptation to mechanical loading. Bone (2009) 1.20
Loading-related regulation of gene expression in bone in the contexts of estrogen deficiency, lack of estrogen receptor alpha and disuse. Bone (2009) 1.19
Local mechanical stimuli regulate bone formation and resorption in mice at the tissue level. PLoS One (2013) 1.04
Effects of genistein on vertebral trabecular bone microstructure, bone mineral density, microcracks, osteocyte density, and bone strength in ovariectomized rats. J Bone Miner Metab (2008) 0.94
A review of osteocyte function and the emerging importance of sclerostin. J Bone Joint Surg Am (2014) 0.89
Loading-related regulation of transcription factor EGR2/Krox-20 in bone cells is ERK1/2 protein-mediated and prostaglandin, Wnt signaling pathway-, and insulin-like growth factor-I axis-dependent. J Biol Chem (2011) 0.89
Non-invasive mouse models of post-traumatic osteoarthritis. Osteoarthritis Cartilage (2015) 0.88
Is interaction between age-dependent decline in mechanical stimulation and osteocyte-estrogen receptor levels the culprit for postmenopausal-impaired bone formation? Osteoporos Int (2012) 0.84
Wnt16 Is Associated with Age-Related Bone Loss and Estrogen Withdrawal in Murine Bone. PLoS One (2015) 0.83
The biomaterial-mediated healing of critical size bone defects in the ovariectomized rat. Osteoporos Int (2014) 0.82
Estrogen receptors' roles in the control of mechanically adaptive bone (re)modeling. Bonekey Rep (2013) 0.82
Manipulation of Ovarian Function Significantly Influenced Trabecular and Cortical Bone Volume, Architecture and Density in Mice at Death. PLoS One (2015) 0.81
Sclerostin serum levels in prostate cancer patients and their relationship with sex steroids. Osteoporos Int (2013) 0.81
Loading and skeletal development and maintenance. J Osteoporos (2010) 0.80
Estrogen receptor-β regulates mechanical signaling in primary osteoblasts. Am J Physiol Endocrinol Metab (2014) 0.78
Mechanical stimulation enhanced estrogen receptor expression and callus formation in diaphyseal long bone fracture healing in ovariectomy-induced osteoporotic rats. Osteoporos Int (2016) 0.76
The RIP1-RIP3 Complex Mediates Osteocyte Necroptosis after Ovariectomy in Rats. PLoS One (2016) 0.76
Peripubertal estrogen levels and physical activity affect femur geometry in young adult women. Osteoporos Int (2009) 0.76
Vitamin K catabolite inhibition of ovariectomy-induced bone loss: structure-activity relationship considerations. Mol Nutr Food Res (2014) 0.75
Strain uses gap junctions to reverse stimulation of osteoblast proliferation by osteocytes. Cell Biochem Funct (2017) 0.75
Regulation of Estrogen Receptor α Expression in the Hypothalamus by Sex Steroids: Implication in the Regulation of Energy Homeostasis. Int J Endocrinol (2015) 0.75
Effects of 8-Prenylnaringenin and Whole-Body Vibration Therapy on a Rat Model of Osteopenia. J Nutr Metab (2016) 0.75
Expression levels of estrogen receptor α mRNA in peripheral blood cells are an independent biomarker for postmenopausal osteoporosis. BBA Clin (2016) 0.75
Interaction between playing golf and HRT on vertebral bone properties in post-menopausal women measured by QCT. Osteoporos Int (2007) 0.75
Wnt/beta-catenin signaling is a component of osteoblastic bone cell early responses to load-bearing and requires estrogen receptor alpha. J Biol Chem (2007) 2.24
Mechanical loading enhances the anabolic effects of intermittent parathyroid hormone (1-34) on trabecular and cortical bone in mice. Bone (2008) 1.76
Functional adaptation to mechanical loading in both cortical and cancellous bone is controlled locally and is confined to the loaded bones. Bone (2009) 1.70
Characterization of the structural features and interactions of sclerostin: molecular insight into a key regulator of Wnt-mediated bone formation. J Biol Chem (2009) 1.60
Bones' adaptive response to mechanical loading is essentially linear between the low strains associated with disuse and the high strains associated with the lamellar/woven bone transition. J Bone Miner Res (2012) 1.33
Estrogen receptor-α is required for the osteogenic response to mechanical loading in a ligand-independent manner involving its activation function 1 but not 2. J Bone Miner Res (2013) 1.22
The mouse fibula as a suitable bone for the study of functional adaptation to mechanical loading. Bone (2009) 1.20
Loading-related regulation of gene expression in bone in the contexts of estrogen deficiency, lack of estrogen receptor alpha and disuse. Bone (2009) 1.19
Sympathetic nervous system does not mediate the load-induced cortical new bone formation. J Bone Miner Res (2005) 1.19
Aging enhances a mechanically-induced reduction in tendon strength by an active process involving matrix metalloproteinase activity. Aging Cell (2007) 1.14
Estrogen receptor α mediates proliferation of osteoblastic cells stimulated by estrogen and mechanical strain, but their acute down-regulation of the Wnt antagonist Sost is mediated by estrogen receptor β. J Biol Chem (2013) 1.11
Characterizing a novel and adjustable noninvasive murine joint loading model. Arthritis Rheum (2011) 1.11
From flat foot to fat foot: structure, ontogeny, function, and evolution of elephant "sixth toes". Science (2011) 1.11
Blockade of beta-adrenergic signaling does not influence the bone mechano-adaptive response in mice. Bone (2007) 1.10
Evaluation of VEGF-mediated signaling in primary human cells reveals a paracrine action for VEGF in osteoblast-mediated crosstalk to endothelial cells. J Cell Physiol (2008) 1.08
A short treatment with an antibody to sclerostin can inhibit bone loss in an ongoing model of colitis. J Bone Miner Res (2009) 1.08
Ammonia impairs neutrophil phagocytic function in liver disease. Hepatology (2008) 1.07
Risedronate does not reduce mechanical loading-related increases in cortical and trabecular bone mass in mice. Bone (2011) 1.06
Sost down-regulation by mechanical strain in human osteoblastic cells involves PGE2 signaling via EP4. FEBS Lett (2011) 1.04
Osteoblast-like cells from estrogen receptor alpha knockout mice have deficient responses to mechanical strain. J Bone Miner Res (2004) 1.03
Heparan sulfate-dependent ERK activation contributes to the overexpression of fibrotic proteins and enhanced contraction by scleroderma fibroblasts. Arthritis Rheum (2008) 1.02
Using digital image correlation to determine bone surface strains during loading and after adaptation of the mouse tibia. J Biomech (2009) 1.02
Characterization of the interaction of sclerostin with the low density lipoprotein receptor-related protein (LRP) family of Wnt co-receptors. J Biol Chem (2012) 1.01
Improbable appendages: Deer antler renewal as a unique case of mammalian regeneration. Semin Cell Dev Biol (2008) 1.01
Mechanical loading-related bone gain is enhanced by tamoxifen but unaffected by fulvestrant in female mice. Endocrinology (2010) 0.99
Age-related impairment of bones' adaptive response to loading in mice is associated with sex-related deficiencies in osteoblasts but no change in osteocytes. J Bone Miner Res (2014) 0.97
Influence of epitopes CD44v3 and CD44v6 in the invasive behavior of fibroblast-like synoviocytes derived from rheumatoid arthritic joints. Arthritis Rheum (2002) 0.97
Time-series transcriptional profiling yields new perspectives on susceptibility to murine osteoarthritis. Arthritis Rheum (2012) 0.96
Regulation of UDP-glucose dehydrogenase is sufficient to modulate hyaluronan production and release, control sulfated GAG synthesis, and promote chondrogenesis. J Cell Physiol (2011) 0.95
Selective activation of the MEK-ERK pathway is regulated by mechanical stimuli in forming joints and promotes pericellular matrix formation. J Biol Chem (2005) 0.94
Human osteoblasts' proliferative responses to strain and 17beta-estradiol are mediated by the estrogen receptor and the receptor for insulin-like growth factor I. J Bone Miner Res (2002) 0.92
A specific mechanomodulatory role for p38 MAPK in embryonic joint articular surface cell MEK-ERK pathway regulation. J Biol Chem (2006) 0.90
Loading-related regulation of transcription factor EGR2/Krox-20 in bone cells is ERK1/2 protein-mediated and prostaglandin, Wnt signaling pathway-, and insulin-like growth factor-I axis-dependent. J Biol Chem (2011) 0.89
Diverse range of fixed positional deformities and bone growth restraint provoked by flaccid paralysis in embryonic chicks. Int J Exp Pathol (2003) 0.87
Extracellular matrix mineralization promotes E11/gp38 glycoprotein expression and drives osteocytic differentiation. PLoS One (2012) 0.86
Targeting hyaluronan of the endothelial glycocalyx for therapeutic intervention. Curr Opin Investig Drugs (2010) 0.86
Lrp5 is not required for the proliferative response of osteoblasts to strain but regulates proliferation and apoptosis in a cell autonomous manner. PLoS One (2012) 0.86
A specific role for phosphoinositide 3-kinase and AKT in osteoblasts? Front Endocrinol (Lausanne) (2012) 0.86
Age-related changes in the response of human articular cartilage to IL-1alpha and transforming growth factor-beta (TGF-beta): chondrocytes exhibit a diminished sensitivity to TGF-beta. J Biol Chem (2003) 0.85
Modifications of gait as predictors of natural osteoarthritis progression in STR/Ort mice. Arthritis Rheumatol (2014) 0.83
Biochemical markers of bone turnover in the domestic cat: relationships with age and feline osteoclastic resorptive lesions. J Nutr (2002) 0.83
Evaluation of serum concentrations of biochemical markers of bone metabolism and insulin-like growth factor I associated with treadmill exercise in young horses. Am J Vet Res (2003) 0.82
Highly homologous Mycobacterium tuberculosis chaperonin 60 proteins with differential CD14 dependencies stimulate cytokine production by human monocytes through cooperative activation of p38 and ERK1/2 mitogen-activated protein kinases. Int Immunopharmacol (2006) 0.82
Hepatic guanylate cyclase activity is decreased in a model of cirrhosis: a quantitative cytochemistry study. FEBS Lett (2006) 0.81
Planar cell polarity aligns osteoblast division in response to substrate strain. J Bone Miner Res (2015) 0.81
Keratan sulfate epitopes exhibit a conserved distribution during joint development that remains undisclosed on the basis of glycosaminoglycan charge density. J Histochem Cytochem (2002) 0.80
The in vitro effect of pH on osteoclasts and bone resorption in the cat: implications for the pathogenesis of FORL. J Cell Physiol (2007) 0.79
Heterotypic contact reveals a COX-2-mediated suppression of osteoblast differentiation by endothelial cells: A negative modulatory role for prostanoids in VEGF-mediated cell: cell communication? Exp Cell Res (2008) 0.79
Exercise affects joint injury risk in young Thoroughbreds in training. Vet J (2012) 0.79
Follistatin-like 3 (FSTL3) mediated silencing of transforming growth factor β (TGFβ) signaling is essential for testicular aging and regulating testis size. Endocrinology (2013) 0.78
Relationship between serum biomarkers of cartilage and bone metabolism and joint injury in young Thoroughbred racehorses in training. Am J Vet Res (2015) 0.77
A scanning electron microscopy study of idiopathic external tooth resorption in the cat. J Periodontol (2005) 0.77
Fracture rate in Thoroughbred racehorses is affected by dam age and parity. Vet J (2006) 0.76
Parathyroid hormone type I receptor expression in mammalian osteoclasts. J Bone Miner Res (2003) 0.75
Vitamin K catabolite inhibition of ovariectomy-induced bone loss: structure-activity relationship considerations. Mol Nutr Food Res (2014) 0.75
Exercise during training is associated with racing performance in Thoroughbreds. Vet J (2009) 0.75
Relationship between stages of the estrous cycle and bone cell activity in Thoroughbreds. Am J Vet Res (2006) 0.75
Four-point bending protocols to study the effects of dynamic strain in osteoblastic cells in vitro. Methods Mol Biol (2015) 0.75