Published in Bioinformatics on July 15, 2006
Information flow analysis of interactome networks. PLoS Comput Biol (2009) 1.68
Determining effects of non-synonymous SNPs on protein-protein interactions using supervised and semi-supervised learning. PLoS Comput Biol (2014) 0.88
Biomarker discovery across annotated and unannotated microarray datasets using semi-supervised learning. BMC Genomics (2008) 0.79
Transcriptional regulatory networks in Saccharomyces cerevisiae. Science (2002) 43.52
Core transcriptional regulatory circuitry in human embryonic stem cells. Cell (2005) 34.93
Control of developmental regulators by Polycomb in human embryonic stem cells. Cell (2006) 28.21
Transcriptional regulatory code of a eukaryotic genome. Nature (2004) 27.21
Polycomb complexes repress developmental regulators in murine embryonic stem cells. Nature (2006) 25.90
A map of the interactome network of the metazoan C. elegans. Science (2004) 15.60
Large-scale sequencing reveals 21U-RNAs and additional microRNAs and endogenous siRNAs in C. elegans. Cell (2006) 15.12
Genome-wide map of nucleosome acetylation and methylation in yeast. Cell (2005) 15.08
Control of pancreas and liver gene expression by HNF transcription factors. Science (2004) 12.05
An improved map of conserved regulatory sites for Saccharomyces cerevisiae. BMC Bioinformatics (2006) 11.13
Tissue-specific transcriptional regulation has diverged significantly between human and mouse. Nat Genet (2007) 6.92
Computational discovery of gene modules and regulatory networks. Nat Biotechnol (2003) 6.55
Systemic RNAi in C. elegans requires the putative transmembrane protein SID-1. Science (2002) 4.72
High-resolution computational models of genome binding events. Nat Biotechnol (2006) 3.74
Global position and recruitment of HATs and HDACs in the yeast genome. Mol Cell (2004) 3.74
Predictive models of molecular machines involved in Caenorhabditis elegans early embryogenesis. Nature (2005) 3.62
Autophagy in chronically ischemic myocardium. Proc Natl Acad Sci U S A (2005) 3.55
Composition and dynamics of the Caenorhabditis elegans early embryonic transcriptome. Development (2003) 3.49
Continuous representations of time-series gene expression data. J Comput Biol (2003) 3.32
Core transcriptional regulatory circuitry in human hepatocytes. Mol Syst Biol (2006) 3.15
Transport of dsRNA into cells by the transmembrane protein SID-1. Science (2003) 3.08
Combining location and expression data for principled discovery of genetic regulatory network models. Pac Symp Biocomput (2002) 3.05
Type 5 adenylyl cyclase disruption increases longevity and protects against stress. Cell (2007) 2.96
Genotype to phenotype: a complex problem. Science (2010) 2.92
A hypothesis-based approach for identifying the binding specificity of regulatory proteins from chromatin immunoprecipitation data. Bioinformatics (2005) 2.52
Integrating interactome, phenome, and transcriptome mapping data for the C. elegans germline. Curr Biol (2002) 2.47
Toggle involving cis-interfering noncoding RNAs controls variegated gene expression in yeast. Proc Natl Acad Sci U S A (2009) 2.36
An antiviral role for the RNA interference machinery in Caenorhabditis elegans. Proc Natl Acad Sci U S A (2005) 2.16
Comparing the continuous representation of time-series expression profiles to identify differentially expressed genes. Proc Natl Acad Sci U S A (2003) 2.10
Body mass index and mortality in China: a 15-year prospective study of 220 000 men. Int J Epidemiol (2012) 2.09
Global regulation of promoter melting in naive lymphocytes. Cell (2013) 2.05
Coordinated binding of NF-kappaB family members in the response of human cells to lipopolysaccharide. Proc Natl Acad Sci U S A (2006) 1.96
Increasing specificity in high-throughput yeast two-hybrid experiments. Methods (2004) 1.93
Caenorhabditis elegans SID-2 is required for environmental RNA interference. Proc Natl Acad Sci U S A (2007) 1.85
High resolution genome wide binding event finding and motif discovery reveals transcription factor spatial binding constraints. PLoS Comput Biol (2012) 1.76
The homeodomain protein PAL-1 specifies a lineage-specific regulatory network in the C. elegans embryo. Development (2005) 1.68
Information flow analysis of interactome networks. PLoS Comput Biol (2009) 1.68
Global gene deletion analysis exploring yeast filamentous growth. Science (2012) 1.67
SID-5 is an endosome-associated protein required for efficient systemic RNAi in C. elegans. Curr Biol (2012) 1.62
Control of transcription by cell size. PLoS Biol (2010) 1.61
MEX-3 interacting proteins link cell polarity to asymmetric gene expression in Caenorhabditis elegans. Development (2002) 1.57
Environmental RNA interference. Trends Genet (2008) 1.54
K-ary clustering with optimal leaf ordering for gene expression data. Bioinformatics (2003) 1.53
Export of RNA silencing from C. elegans tissues does not require the RNA channel SID-1. Proc Natl Acad Sci U S A (2009) 1.51
Deconvolving cell cycle expression data with complementary information. Bioinformatics (2004) 1.51
Synthesis and biological evaluation of helicid analogues as novel acetylcholinesterase inhibitors. Eur J Med Chem (2007) 1.48
Differentiated human stem cells resemble fetal, not adult, β cells. Proc Natl Acad Sci U S A (2014) 1.44
Global control of motor neuron topography mediated by the repressive actions of a single hox gene. Neuron (2010) 1.41
Modularity and dynamics of cellular networks. PLoS Comput Biol (2006) 1.37
Synergistic binding of transcription factors to cell-specific enhancers programs motor neuron identity. Nat Neurosci (2013) 1.36
Neck circumference as an independent predictive contributor to cardio-metabolic syndrome. Cardiovasc Diabetol (2013) 1.35
Discovering homotypic binding events at high spatial resolution. Bioinformatics (2010) 1.33
Synthetic lethal analysis of Caenorhabditis elegans posterior embryonic patterning genes identifies conserved genetic interactions. Genome Biol (2005) 1.33
SID-1 is a dsRNA-selective dsRNA-gated channel. RNA (2011) 1.33
Analysis of the mouse embryonic stem cell regulatory networks obtained by ChIP-chip and ChIP-PET. Genome Biol (2008) 1.29
Embryonic stem cell-based mapping of developmental transcriptional programs. Nat Methods (2011) 1.20
Ligand-dependent dynamics of retinoic acid receptor binding during early neurogenesis. Genome Biol (2011) 1.19
Automated discovery of functional generality of human gene expression programs. PLoS Comput Biol (2007) 1.18
The STAR/Maxi-KH domain protein GLD-1 mediates a developmental switch in the translational control of C. elegans PAL-1. Development (2004) 1.17
Adenylyl cyclase type 5 protein expression during cardiac development and stress. Am J Physiol Heart Circ Physiol (2009) 1.16
Transport of sequence-specific RNA interference information between cells. Annu Rev Genet (2007) 1.16
Triptolide induces anti-inflammatory cellular responses. Am J Transl Res (2009) 1.15
Comparison of diverse developmental transcriptomes reveals that coexpression of gene neighbors is not evolutionarily conserved. Genome Res (2009) 1.08
Body mass index and mortality from lung cancer in smokers and nonsmokers: a nationally representative prospective study of 220,000 men in China. Int J Cancer (2009) 1.08
Cyclic tensile strain triggers a sequence of autocrine and paracrine signaling to regulate angiogenic sprouting in human vascular cells. Proc Natl Acad Sci U S A (2009) 1.06
Translational control of maternal RNAs. WormBook (2005) 1.04
Rapid haplotype inference for nuclear families. Genome Biol (2010) 1.03
Uptake of extracellular double-stranded RNA by SID-2. Mol Cell (2012) 1.02
The SID-1 double-stranded RNA transporter is not selective for dsRNA length. RNA (2009) 1.02
High-resolution genetic mapping with pooled sequencing. BMC Bioinformatics (2012) 1.01
Two classes of silencing RNAs move between Caenorhabditis elegans tissues. Nat Struct Mol Biol (2011) 1.00
Type 5 adenylyl cyclase increases oxidative stress by transcriptional regulation of manganese superoxide dismutase via the SIRT1/FoxO3a pathway. Circulation (2013) 0.99
Tissue specificity of Caenorhabditis elegans enhanced RNA interference mutants. Genetics (2011) 0.98
A multicenter study of BRD2 as a risk factor for juvenile myoclonic epilepsy. Epilepsia (2007) 0.98
Mutations in a beta-tubulin disrupt spindle orientation and microtubule dynamics in the early Caenorhabditis elegans embryo. Mol Biol Cell (2003) 0.97
Systematic analysis of pleiotropy in C. elegans early embryogenesis. PLoS Comput Biol (2008) 0.96
Mammalian target of rapamycin and Rictor control neutrophil chemotaxis by regulating Rac/Cdc42 activity and the actin cytoskeleton. Mol Biol Cell (2013) 0.96
Pairing of competitive and topologically distinct regulatory modules enhances patterned gene expression. Mol Syst Biol (2008) 0.95
The non-receptor tyrosine kinase Lyn controls neutrophil adhesion by recruiting the CrkL-C3G complex and activating Rap1 at the leading edge. J Cell Sci (2011) 0.92
Composition and regulation of maternal and zygotic transcriptomes reflects species-specific reproductive mode. Genome Biol (2010) 0.90
A genomic bias for genotype-environment interactions in C. elegans. Mol Syst Biol (2012) 0.90
Association of MTHFR C677T and SHMT(1) C1420T with susceptibility to ESCC and GCA in a high incident region of Northern China. Cancer Causes Control (2007) 0.90
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Feed-forward regulation of a cell fate determinant by an RNA-binding protein generates asymmetry in yeast. Genetics (2010) 0.89
RNA interference in Caenorhabditis elegans: uptake, mechanism, and regulation. Parasitology (2011) 0.89
Conserved tyrosine kinase promotes the import of silencing RNA into Caenorhabditis elegans cells. Proc Natl Acad Sci U S A (2012) 0.86
The nuclear argonaute NRDE-3 contributes to transitive RNAi in Caenorhabditis elegans. Genetics (2013) 0.86
Cardiomyocyte overexpression of the α1A-adrenergic receptor in the rat phenocopies second but not first window preconditioning. Am J Physiol Heart Circ Physiol (2012) 0.84
Progression from mitotic catastrophe to germ cell death in Caenorhabditis elegans lis-1 mutants requires the spindle checkpoint. Dev Biol (2007) 0.83
MyoD, modularity, and myogenesis: conservation of regulators and redundancy in C. elegans. Genes Dev (2006) 0.83
Transcriptional expression of Stilbene synthase genes are regulated developmentally and differentially in response to powdery mildew in Norton and Cabernet Sauvignon grapevine. Plant Sci (2012) 0.81
Genetic inhibition of calcineurin induces diastolic dysfunction in mice with chronic pressure overload. Am J Physiol Heart Circ Physiol (2009) 0.81