PubRank

Reinhard Buettner

Author PubWeight™ 141.06‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription. Nature 2005 8.53
2 Frequent and focal FGFR1 amplification associates with therapeutically tractable FGFR1 dependency in squamous cell lung cancer. Sci Transl Med 2010 6.39
3 Bats host major mammalian paramyxoviruses. Nat Commun 2012 4.15
4 Cooperative demethylation by JMJD2C and LSD1 promotes androgen receptor-dependent gene expression. Nat Cell Biol 2007 3.89
5 Polyclonal evolution of multiple secondary KIT mutations in gastrointestinal stromal tumors under treatment with imatinib mesylate. Clin Cancer Res 2006 3.00
6 MYCN regulates oncogenic MicroRNAs in neuroblastoma. Int J Cancer 2008 2.76
7 Lysine-specific demethylase 1 is strongly expressed in poorly differentiated neuroblastoma: implications for therapy. Cancer Res 2009 2.65
8 Androgen receptor coactivators lysine-specific histone demethylase 1 and four and a half LIM domain protein 2 predict risk of prostate cancer recurrence. Cancer Res 2006 2.62
9 Risks of less common cancers in proven mutation carriers with lynch syndrome. J Clin Oncol 2012 2.59
10 Lysine-specific demethylase 1 (LSD1) is highly expressed in ER-negative breast cancers and a biomarker predicting aggressive biology. Carcinogenesis 2009 2.54
11 Phosphorylation of histone H3 at threonine 11 establishes a novel chromatin mark for transcriptional regulation. Nat Cell Biol 2007 2.50
12 Early prediction of nonprogression in advanced non-small-cell lung cancer treated with erlotinib by using [(18)F]fluorodeoxyglucose and [(18)F]fluorothymidine positron emission tomography. J Clin Oncol 2011 2.10
13 Phosphorylation of histone H3T6 by PKCbeta(I) controls demethylation at histone H3K4. Nature 2010 2.01
14 Clear cell sarcoma-like tumor with osteoclast-like giant cells in the small bowel: further evidence for a new tumor entity. Int J Surg Pathol 2005 1.74
15 The transcriptional coactivator FHL2 transmits Rho signals from the cell membrane into the nucleus. EMBO J 2002 1.72
16 Attenuation of allergic contact dermatitis through the endocannabinoid system. Science 2007 1.70
17 Definition of a fluorescence in-situ hybridization score identifies high- and low-level FGFR1 amplification types in squamous cell lung cancer. Mod Pathol 2012 1.50
18 Tumor VEGF:VEGFR2 autocrine feed-forward loop triggers angiogenesis in lung cancer. J Clin Invest 2013 1.41
19 Mutations in multiple PKD genes may explain early and severe polycystic kidney disease. J Am Soc Nephrol 2011 1.38
20 Characterization of methylthioadenosin phosphorylase (MTAP) expression in malignant melanoma. Am J Pathol 2003 1.36
21 Tumours from MSH2 mutation carriers show loss of MSH2 expression but many tumours from MLH1 mutation carriers exhibit weak positive MLH1 staining. J Pathol 2005 1.35
22 Novel germline mutation of KIT associated with familial gastrointestinal stromal tumors and mastocytosis. Gastroenterology 2005 1.32
23 A novel inducible transactivation domain in the androgen receptor: implications for PRK in prostate cancer. EMBO J 2003 1.32
24 A mouse model for cystic biliary dysgenesis in autosomal recessive polycystic kidney disease (ARPKD). Hepatology 2005 1.31
25 Placental failure and impaired vasculogenesis result in embryonic lethality for neuropathy target esterase-deficient mice. Mol Cell Biol 2004 1.27
26 Microsatellite instability of selective target genes in HNPCC-associated colon adenomas. Oncogene 2005 1.26
27 Epigenetic regulation of cancer growth by histone demethylases. Int J Cancer 2010 1.23
28 Spectrum and frequencies of mutations in MSH2 and MLH1 identified in 1,721 German families suspected of hereditary nonpolyposis colorectal cancer. Int J Cancer 2005 1.20
29 Primitive neuroectodermal tumor (PNET) in the differential diagnosis of malignant kidney tumors. Pathol Res Pract 2002 1.20
30 CD74-NRG1 fusions in lung adenocarcinoma. Cancer Discov 2014 1.19
31 Impairment of prostate cancer cell growth by a selective and reversible lysine-specific demethylase 1 inhibitor. Int J Cancer 2012 1.18
32 Multiple colon carcinomas in a patient with Cowden syndrome. Int J Mol Med 2006 1.17
33 Upregulation of HMG1 leads to melanoma inhibitory activity expression in malignant melanoma cells and contributes to their malignancy phenotype. Mol Cell Biol 2003 1.17
34 Deficiency in the LIM-only protein Fhl2 impairs skin wound healing. J Cell Biol 2007 1.13
35 Aberrant splicing in MLH1 and MSH2 due to exonic and intronic variants. Hum Genet 2005 1.13
36 β-catenin (CTNNB1) mutations and clinicopathological features of mesenteric desmoid-type fibromatosis. Histopathology 2012 1.12
37 Novel strategy for optimal sequential application of clinical criteria, immunohistochemistry and microsatellite analysis in the diagnosis of hereditary nonpolyposis colorectal cancer. Int J Cancer 2006 1.11
38 Distinct spatial expression patterns of AP-2alpha and AP-2gamma in non-neoplastic human breast and breast cancer. Mod Pathol 2005 1.10
39 Active detachment involves inhibition of cell-matrix contacts of malignant melanoma cells by secretion of melanoma inhibitory activity. Lab Invest 2003 1.10
40 Adenoviral expression of a transforming growth factor-beta1 antisense mRNA is effective in preventing liver fibrosis in bile-duct ligated rats. BMC Gastroenterol 2003 1.08
41 Ultrastructural cartilage abnormalities in MIA/CD-RAP-deficient mice. Mol Cell Biol 2002 1.06
42 Activation of phosphatidylinositol-3'-kinase/AKT signaling is essential in hepatoblastoma survival. Clin Cancer Res 2009 1.02
43 Identification of novel fusion genes in lung cancer using breakpoint assembly of transcriptome sequencing data. Genome Biol 2015 1.01
44 Noncancerous PTGS2 DNA fragments of apoptotic origin in sera of prostate cancer patients qualify as diagnostic and prognostic indicators. Int J Cancer 2008 1.00
45 MicroRNAs in the pathogenesis of neuroblastoma. Cancer Lett 2008 1.00
46 SNAI1-mediated epithelial-mesenchymal transition confers chemoresistance and cellular plasticity by regulating genes involved in cell death and stem cell maintenance. PLoS One 2013 1.00
47 Genome-wide expression profiling reveals new insights into pathogenesis and progression of testicular germ cell tumors. Cancer Genomics Proteomics 2007 0.99
48 High-resolution melting analysis as a sensitive prescreening diagnostic tool to detect KRAS , BRAF , PIK3CA , and AKT1 mutations in formalin-fixed, paraffin-embedded tissues. Arch Pathol Lab Med 2012 0.99
49 Terminal renal failure in mice lacking transcription factor AP-2 beta. Lab Invest 2003 0.98
50 Identification and embryonic expression of a new AP-2 transcription factor, AP-2 epsilon. Dev Dyn 2004 0.98
51 A dual role of linker histone H1.4 Lys 34 acetylation in transcriptional activation. Genes Dev 2012 0.97
52 Lysine-specific demethylase 1 is highly expressed in solitary fibrous tumors, synovial sarcomas, rhabdomyosarcomas, desmoplastic small round cell tumors, and malignant peripheral nerve sheath tumors. Hum Pathol 2011 0.97
53 Regulatory BCL2 promoter polymorphism (-938C>A) is associated with adverse outcome in patients with prostate carcinoma. Int J Cancer 2011 0.95
54 Kaposi's sarcoma of the gastrointestinal tract: report of two cases and review of the literature. Pathol Res Pract 2007 0.95
55 Epidermal growth factor receptor mutations in non-small cell lung cancer influence downstream Akt, MAPK and Stat3 signaling. J Cancer Res Clin Oncol 2008 0.95
56 Association of familial colorectal cancer with variants in the E-cadherin (CDH1) and cyclin D1 (CCND1) genes. Int J Colorectal Dis 2007 0.95
57 Specific expression and regulation of the new melanoma inhibitory activity-related gene MIA2 in hepatocytes. J Biol Chem 2003 0.95
58 The role of molecular diagnostics in cancer diagnosis and treatment. Onkologie 2012 0.93
59 Rapid growth of invasive metastatic melanoma in carcinogen-treated hepatocyte growth factor/scatter factor-transgenic mice carrying an oncogenic CDK4 mutation. Am J Pathol 2006 0.91
60 Pitfalls in the detection of t(11;22) translocation by fluorescence in situ hybridization and RT-PCR: a single-blinded study. Diagn Mol Pathol 2006 0.90
61 Phosphatidylinositol-3'-kinase/AKT signaling is essential in synovial sarcoma. Int J Cancer 2011 0.90
62 Establishing the protein MIA (melanoma inhibitory activity) as a marker for chondrocyte differentiation. Biomaterials 2003 0.89
63 Implementation of Amplicon Parallel Sequencing Leads to Improvement of Diagnosis and Therapy of Lung Cancer Patients. J Thorac Oncol 2015 0.89
64 Fibroblast growth factor receptor 1 as a putative therapy target in colorectal cancer. Digestion 2013 0.89
65 A heart-hand syndrome gene: Tfap2b plays a critical role in the development and remodeling of mouse ductus arteriosus and limb patterning. PLoS One 2011 0.88
66 Distinguishing medullary carcinoma of the breast from high-grade hormone receptor-negative invasive ductal carcinoma: an immunohistochemical approach. Histopathology 2010 0.88
67 Saturation biopsy improves preoperative Gleason scoring of prostate cancer. Pathol Res Pract 2008 0.88
68 Potential complications of transcatheter aortic valve implantation (TAVI)-an autopsy perspective. Cardiovasc Pathol 2013 0.87
69 Ten recently identified associations between nsSNPs and colorectal cancer could not be replicated in German families. Cancer Lett 2008 0.87
70 FHL2 expression in peritumoural fibroblasts correlates with lymphatic metastasis in sporadic but not in HNPCC-associated colon cancer. Lab Invest 2011 0.87
71 Four-and-a-half LIM domain protein 2 is a novel regulator of sphingosine 1-phosphate receptor 1 in CCL19-induced dendritic cell migration. J Immunol 2010 0.86
72 Deficiency in the LIM-only protein FHL2 impairs assembly of extracellular matrix proteins. FASEB J 2008 0.86
73 The low-affinity neurotrophin receptor, p75, is upregulated in ganglioneuroblastoma/ganglioneuroma and reduces tumorigenicity of neuroblastoma cells in vivo. Int J Cancer 2009 0.85
74 The peripheral zone of the prostate is more prone to tumor development than the transitional zone: is the ETS family the key? Mol Med Rep 2011 0.85
75 Regulation of the noradrenaline neurotransmitter phenotype by the transcription factor AP-2beta. J Biol Chem 2008 0.85
76 Contribution of common monoallelic MUTYH gene variants in German patients with familial colorectal cancer. Cancer Biomark 2008 0.85
77 Comparison of histopathological and gene expression-based typing of cancer of unknown primary. Virchows Arch 2009 0.84
78 Lysine-specific demethylase 1 (LSD1) and histone deacetylase 1 (HDAC1) synergistically repress proinflammatory cytokines and classical complement pathway components. Biochem Biophys Res Commun 2012 0.84
79 Challenges and pitfalls in HNPCC screening by microsatellite analysis and immunohistochemistry. J Mol Diagn 2004 0.84
80 Current diagnostic methods of HER-2/neu detection in breast cancer with special regard to real-time PCR. Am J Surg Pathol 2003 0.83
81 Analysis of laser-microdissected prostate cancer tissues reveals potential tumor markers. Int J Mol Med 2011 0.83
82 Impaired intestinal wound healing in Fhl2-deficient mice is due to disturbed collagen metabolism. Exp Cell Res 2008 0.83
83 Overlapping expression patterns and redundant roles for AP-2 transcription factors in the developing mammalian retina. Dev Dyn 2012 0.82
84 Transcription factor AP2alpha (TFAP2a) regulates differentiation and proliferation of neuroblastoma cells. Cancer Lett 2008 0.82
85 Acute adenoviral infection of a graft by serotype 35 following renal transplantation. Pathol Res Pract 2003 0.82
86 Nine novel pathogenic germline mutations in MLH1, MSH2, MSH6 and PMS2 in families with Lynch syndrome. Acta Oncol 2007 0.81
87 Effects of common haplotypes of the ileal sodium dependent bile acid transporter gene on the development of sporadic and familial colorectal cancer: a case control study. BMC Med Genet 2008 0.81
88 High nuclear poly(adenosine diphosphate-ribose) polymerase expression is predictive for BRCA1- and BRCA2-deficient breast cancer. J Clin Oncol 2011 0.81
89 Loss of p14ARF expression in melanoma. Arch Dermatol Res 2002 0.81
90 Loss of the keratin cytoskeleton is not sufficient to induce epithelial mesenchymal transition in a novel KRAS driven sporadic lung cancer mouse model. PLoS One 2013 0.81
91 Hypothesis: Possible role of retinoic acid therapy in patients with biallelic mismatch repair gene defects. Eur J Pediatr 2007 0.81
92 Familial gastrointestinal stromal tumors caused by the novel KIT exon 17 germline mutation N822Y. Am J Surg Pathol 2008 0.80
93 Comprehensive gene expression microarray analysis of Ets-1 blockade in PC3 prostate cancer cells and correlations with prostate cancer tissues: Insights into genes involved in the metastatic cascade. Int J Mol Med 2011 0.80
94 Deep ion sequencing of amplicon adapter ligated libraries: a novel tool in molecular diagnostics of formalin fixed and paraffin embedded tissues. J Clin Pathol 2013 0.80
95 Role of S128R polymorphism of E-selectin in colon metastasis formation. Int J Cancer 2007 0.80
96 Identification of immunity-related genes in prostate cancer and potential role of the ETS family of transcription factors in their regulation. Int J Mol Med 2011 0.80
97 Neurocytoma arising in the pelvis. Virchows Arch 2003 0.80
98 The H3K4me3 histone demethylase Fbxl10 is a regulator of chemokine expression, cellular morphology, and the metabolome of fibroblasts. J Biol Chem 2012 0.80
99 p53 Codon 72 polymorphism, loss of heterozygosity and high-risk human papillomavirus infection in a low-incidence German esophageal squamous cell carcinoma patient cohort. Oncol Rep 2007 0.79
100 Down-regulation of COOH-terminal binding protein expression in malignant melanomas leads to induction of MIA expression. Cancer Res 2002 0.79
101 Pathological features of breast and ovarian cancers in RAD51C germline mutation carriers. Virchows Arch 2014 0.79
102 Ets-1 is implicated in the regulation of androgen co-regulator FHL2 and reveals specificity for migration, but not invasion, of PC3 prostate cancer cells. Oncol Rep 2011 0.79
103 DNA methylation in patients with colorectal cancer--correlation with some clinical and morphological features and with local tumour invasion. Folia Med (Plovdiv) 2010 0.78
104 Backbone dynamics of the human MIA protein studied by (15)N NMR relaxation: implications for extended interactions of SH3 domains. Protein Sci 2003 0.78
105 Differential expression of ETS family members in prostate cancer tissues and androgen-sensitive and insensitive prostate cancer cell lines. Int J Mol Med 2011 0.78
106 Cloning, expression and characterization of the murine orthologue of SBF2, the gene mutated in Charcot-Marie-Tooth disease type 4B2. Gene Expr Patterns 2006 0.78
107 Transcription factor AP-2β regulates the neurotransmitter phenotype and maturation of chromaffin cells. Mol Cell Neurosci 2010 0.77
108 Transient perioperative pharmacologic inhibition of muscularis macrophages as a target for prophylaxis of postoperative ileus does not affect anastomotic healing in mice. Surgery 2010 0.77
109 AP-2δ is a crucial transcriptional regulator of the posterior midbrain. PLoS One 2011 0.77
110 Genes differentially expressed in the peripheral zone compared to the transitional zone of the normal human prostate and their potential regulation by ETS factors. Mol Med Rep 2011 0.76
111 Comparative morphometric analysis of primary versus recurrent basal cell carcinoma and of histological subtypes. Significance of morphometry of the nuclei. Anticancer Res 2003 0.76
112 Molecular evidence for a clonal relationship between multiple lesions in patients with unknown primary adenocarcinoma. Int J Cancer 2008 0.75
113 Regulation of prostate cancer immunity-related genes in PC3 prostate cancer cells by ETS-1. Oncol Lett 2011 0.75
114 Macroscopic and histopathologic findings in a laparoschisis model in fetal sheep: comparisons with gastroschisis in human fetuses and implications for prenatal interventions. Arch Gynecol Obstet 2011 0.75
115 TGF-β1-dependent induction and nuclear translocation of FHL2 promotes keratin expression in pilomatricoma. Virchows Arch 2014 0.75
116 Orofaciodigital syndrome type IV (Mohr-Majewski syndrome): report of a family with two affected siblings. Pediatr Dev Pathol 2007 0.75