Interferon-gamma in combination with carboplatin and paclitaxel as a safe and effective first-line treatment option for advanced ovarian cancer: results of a phase I/II study.

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Published in Int J Gynecol Cancer on August 03, 2006

Authors

C Marth1, G H Windbichler, H Hausmaninger, E Petru, K Estermann, A Pelzer, E Mueller-Holzner

Author Affiliations

1: Department of Obstetrics and Gynaecology, Innsbruck Medical University, Austria. christian.marth@uibk.ac.at

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Seroepidemiological study of gonorrhoea in Ethiopian women. 2. Socioeconomic picture. Genitourin Med (1991) 0.89

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Do primiparas aged 40 years or older carry an increased obstetric risk? Prev Med (1999) 0.79

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CEOP-IMVP-Dexa in the treatment of aggressive lymphomas: an Austrian multicenter trial. J Clin Oncol (1996) 0.75

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[Current status of diagnosis and therapy of trophoblast tumors]. Gynakol Rundsch (1990) 0.75

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[Scalenus biopsy in diagnosis of ovarian and uterine cancers]. HNO (1990) 0.75

Interferon-alpha for the treatment of elderly patients with chronic myeloid leukaemia. Leuk Res (1998) 0.75

[Lymph cysts following radical operations of cervix and ovarian cancer]. Gynakol Rundsch (1990) 0.75

[Lymph node status in corpus and cervix cancer]. Gynakol Rundsch (1991) 0.75

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Pirarubicin (4'-o-tetrahydropyranil-adriamycin) for treatment of advanced breast cancer. A Clinical Phase II study. Invest New Drugs (1990) 0.75

Parity as an independent prognostic factor in malignant mixed mesodermal tumors of the endometrium. Gynecol Oncol (1997) 0.75

Pelvic and para-aortic lymphadenectomy in cervical cancer. Baillieres Clin Obstet Gynaecol (1988) 0.75

Prognostic implications of residual tumour volume in stage III ovarian cancer patients undergoing adjuvant cytotoxic chemotherapy. Baillieres Clin Obstet Gynaecol (1989) 0.75

[Hydatidiform mole, trophoblastic tumor/choriocarcinoma]. Gynakol Geburtshilfliche Rundsch (1992) 0.75

Perioperative antibiotic prophylaxis in patients undergoing radical surgery for gynecologic cancer: single dose versus multiple dose administration. Eur J Gynaecol Oncol (1993) 0.75

[Therapy of uterine cancer: a review]. Gynakol Rundsch (1988) 0.75

[Change in obstetrical risk in adolescent primiparous patients--a comparative study]. Gynakol Rundsch (1989) 0.75

[Immunity of habitual abortion. Principles and current status of research]. Gynakol Rundsch (1988) 0.75

Combination treatment based on metabolic effects of dinaline. J Cancer Res Clin Oncol (1995) 0.75

[Diagnostic value of combined vaginal ultrasound and hysteroscopy in peri- and postmenopausal bleeding]. Gynakol Geburtshilfliche Rundsch (1996) 0.75

Macroprolactinomas and functionless pituitary tumours. Immunostaining and effect of dopamine agonist therapy. Acta Endocrinol (Copenh) (1987) 0.75

[The value of preventive ovariectomy at the time of hysterectomy for prevention of ovarian cancer]. Gynakol Rundsch (1991) 0.75

The value of morphometry to predict chemotherapy response in advanced ovarian cancer. Pathol Res Pract (1989) 0.75