PubRank

M Kay Washington

Author PubWeight™ 113.11‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 TGF-beta signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia. Science 2004 10.23
2 Experimentally derived metastasis gene expression profile predicts recurrence and death in patients with colon cancer. Gastroenterology 2009 4.08
3 Soluble proteins produced by probiotic bacteria regulate intestinal epithelial cell survival and growth. Gastroenterology 2006 3.96
4 EGF receptor is required for KRAS-induced pancreatic tumorigenesis. Cancer Cell 2012 3.19
5 Claudin-1 regulates cellular transformation and metastatic behavior in colon cancer. J Clin Invest 2005 3.02
6 Importance of epidermal growth factor receptor signaling in establishment of adenomas and maintenance of carcinomas during intestinal tumorigenesis. Proc Natl Acad Sci U S A 2002 2.65
7 Histopathologic diagnosis of chronic graft-versus-host disease: National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: II. Pathology Working Group Report. Biol Blood Marrow Transplant 2006 2.63
8 Matrix metalloproteinase-7 is expressed by pancreatic cancer precursors and regulates acinar-to-ductal metaplasia in exocrine pancreas. J Clin Invest 2002 2.28
9 Hdac3 is essential for the maintenance of chromatin structure and genome stability. Cancer Cell 2010 2.20
10 Colon-specific delivery of a probiotic-derived soluble protein ameliorates intestinal inflammation in mice through an EGFR-dependent mechanism. J Clin Invest 2011 2.16
11 Transforming growth factor beta receptor type II inactivation induces the malignant transformation of intestinal neoplasms initiated by Apc mutation. Cancer Res 2006 2.14
12 Loss of FOXA1/2 is essential for the epithelial-to-mesenchymal transition in pancreatic cancer. Cancer Res 2010 1.69
13 Targeted inhibition of SRC kinase signaling attenuates pancreatic tumorigenesis. Mol Cancer Ther 2010 1.67
14 Molecular imaging of therapeutic response to epidermal growth factor receptor blockade in colorectal cancer. Clin Cancer Res 2008 1.66
15 Aberrantly methylated CDKN2A, MGMT, and MLH1 in colon polyps and in fecal DNA from patients with colorectal polyps. Clin Cancer Res 2005 1.59
16 Combined blockade of Src kinase and epidermal growth factor receptor with gemcitabine overcomes STAT3-mediated resistance of inhibition of pancreatic tumor growth. Clin Cancer Res 2011 1.55
17 Notch signaling regulates formation of the three-dimensional architecture of intrahepatic bile ducts in mice. Hepatology 2010 1.53
18 TGF-beta receptor inactivation and mutant Kras induce intestinal neoplasms in mice via a beta-catenin-independent pathway. Gastroenterology 2009 1.50
19 p120-catenin is essential for maintenance of barrier function and intestinal homeostasis in mice. J Clin Invest 2010 1.41
20 Smad4-mediated signaling inhibits intestinal neoplasia by inhibiting expression of β-catenin. Gastroenterology 2011 1.40
21 Kinase suppressor of Ras-1 protects intestinal epithelium from cytokine-mediated apoptosis during inflammation. J Clin Invest 2004 1.40
22 Epithelial tissues have varying degrees of susceptibility to Kras(G12D)-initiated tumorigenesis in a mouse model. PLoS One 2011 1.38
23 Helicobacter pylori strain-selective induction of matrix metalloproteinase-7 in vitro and within gastric mucosa. Gastroenterology 2003 1.34
24 The aurora kinase A inhibitor MLN8237 enhances cisplatin-induced cell death in esophageal adenocarcinoma cells. Mol Cancer Ther 2012 1.33
25 Urine PGE-M: A metabolite of prostaglandin E2 as a potential biomarker of advanced colorectal neoplasia. Clin Gastroenterol Hepatol 2006 1.32
26 Epidermal growth factor receptor activation protects gastric epithelial cells from Helicobacter pylori-induced apoptosis. Gastroenterology 2009 1.28
27 Overexpression of heparin-binding EGF-like growth factor in mouse pancreas results in fibrosis and epithelial metaplasia. Gastroenterology 2003 1.28
28 Multiple, temporal-specific roles for HNF6 in pancreatic endocrine and ductal differentiation. Mech Dev 2009 1.23
29 Overexpression of OATP1B3 confers apoptotic resistance in colon cancer. Cancer Res 2008 1.20
30 Smad4 regulates claudin-1 expression in a transforming growth factor-beta-independent manner in colon cancer cells. Cancer Res 2007 1.19
31 High dietary salt intake exacerbates Helicobacter pylori-induced gastric carcinogenesis. Infect Immun 2013 1.16
32 Mtgr1 is a transcriptional corepressor that is required for maintenance of the secretory cell lineage in the small intestine. Mol Cell Biol 2005 1.16
33 Loss of TFF1 is associated with activation of NF-κB-mediated inflammation and gastric neoplasia in mice and humans. J Clin Invest 2011 1.15
34 The apolipoprotein E-mimetic peptide COG112 inhibits NF-kappaB signaling, proinflammatory cytokine expression, and disease activity in murine models of colitis. J Biol Chem 2010 1.14
35 STAT6 activation in ulcerative colitis: a new target for prevention of IL-13-induced colon epithelial cell dysfunction. Inflamm Bowel Dis 2011 1.13
36 Berberine promotes recovery of colitis and inhibits inflammatory responses in colonic macrophages and epithelial cells in DSS-treated mice. Am J Physiol Gastrointest Liver Physiol 2011 1.12
37 Targeted imaging of colonic tumors in smad3-/- mice discriminates cancer and inflammation. Mol Cancer Res 2007 1.11
38 Deletion of Mtgr1 sensitizes the colonic epithelium to dextran sodium sulfate-induced colitis. Gastroenterology 2006 1.09
39 L-arginine supplementation improves responses to injury and inflammation in dextran sulfate sodium colitis. PLoS One 2012 1.08
40 Aurora kinase A promotes inflammation and tumorigenesis in mice and human gastric neoplasia. Gastroenterology 2013 1.07
41 Deciphering the unique microRNA signature in human esophageal adenocarcinoma. PLoS One 2013 1.05
42 Raf protects against colitis by promoting mouse colon epithelial cell survival through NF-kappaB. Gastroenterology 2008 1.05
43 CDC2/CDK1 expression in esophageal adenocarcinoma and precursor lesions serves as a diagnostic and cancer progression marker and potential novel drug target. Am J Surg Pathol 2005 1.04
44 Epidermal growth factor receptor inhibits colitis-associated cancer in mice. J Clin Invest 2012 1.01
45 Aberrant DNA methylation occurs in colon neoplasms arising in the azoxymethane colon cancer model. Mol Carcinog 2010 1.00
46 BVES regulates EMT in human corneal and colon cancer cells and is silenced via promoter methylation in human colorectal carcinoma. J Clin Invest 2011 1.00
47 Delineation of a carcinogenic Helicobacter pylori proteome. Mol Cell Proteomics 2009 1.00
48 Adenoma formation following limited ablation of p120-catenin in the mouse intestine. PLoS One 2011 0.98
49 3'-Deoxy-3'-18F-fluorothymidine PET predicts response to (V600E)BRAF-targeted therapy in preclinical models of colorectal cancer. J Nucl Med 2013 0.97
50 STAT6 deficiency ameliorates severity of oxazolone colitis by decreasing expression of claudin-2 and Th2-inducing cytokines. J Immunol 2013 0.96
51 Heterozygous disruption of the PTEN promotes intestinal neoplasia in APCmin/+ mouse: roles of osteopontin. Carcinogenesis 2007 0.96
52 Novel mechanistic insights into ectodomain shedding of EGFR Ligands Amphiregulin and TGF-α: impact on gastrointestinal cancers driven by secondary bile acids. Cancer Res 2014 0.95
53 Gastric adenocarcinoma has a unique microRNA signature not present in esophageal adenocarcinoma. Cancer 2013 0.95
54 Systemic nf-kappaB activation in a transgenic mouse model of acute pancreatitis. J Surg Res 2003 0.95
55 IL-23 Contributes to Control of Chronic Helicobacter Pylori Infection and the Development of T Helper Responses in a Mouse Model. Front Immunol 2012 0.94
56 Genetic and pharmacologic alteration of cathepsin expression influences reovirus pathogenesis. J Virol 2009 0.93
57 DNA methylation profiling in Barrett's esophagus and esophageal adenocarcinoma reveals unique methylation signatures and molecular subclasses. Epigenetics 2011 0.93
58 Debating deposits: an interobserver variability study of lymph nodes and pericolonic tumor deposits in colonic adenocarcinoma. Arch Pathol Lab Med 2013 0.92
59 Human epididymis protein 4 is up-regulated in gastric and pancreatic adenocarcinomas. Hum Pathol 2012 0.92
60 Enhanced tumor formation in cyclin D1 x transforming growth factor beta1 double transgenic mice with characterization by magnetic resonance imaging. Cancer Res 2004 0.88
61 Identification of early intestinal neoplasia protein biomarkers using laser capture microdissection and MALDI MS. Mol Cell Proteomics 2009 0.87
62 ErbB2 and ErbB3 regulate recovery from dextran sulfate sodium-induced colitis by promoting mouse colon epithelial cell survival. Lab Invest 2011 0.87
63 A standards based ontological approach to information handling for use by organizations providing human tissue for research. Cancer Inform 2008 0.86
64 Matrix metalloproteinase-7 and premalignant host responses in Helicobacter pylori-infected mice. Cancer Res 2010 0.86
65 Biliary reconstruction is enhanced with a collagen-polyethylene glycol sealant. Am Surg 2002 0.84
66 CD44 upregulation in E-cadherin-negative esophageal cancers results in cell invasion. PLoS One 2011 0.83
67 Transmembrane and soluble isoforms of heparin-binding epidermal growth factor-like growth factor regulate distinct processes in the pancreas. Gastroenterology 2009 0.83
68 A peptide-based positron emission tomography probe for in vivo detection of caspase activity in apoptotic cells. Clin Cancer Res 2014 0.83
69 Do adverse histopathologic findings in colorectal cancer patients explain disparate outcomes? J Natl Med Assoc 2006 0.82
70 Pattern of breast cancer susceptibility gene 1 expression is a potential prognostic biomarker in resectable pancreatic ductal adenocarcinoma. Pancreas 2013 0.81
71 Deletion of cationic amino acid transporter 2 exacerbates dextran sulfate sodium colitis and leads to an IL-17-predominant T cell response. Am J Physiol Gastrointest Liver Physiol 2013 0.81
72 Dynamic distribution of claudin proteins in pancreatic epithelia undergoing morphogenesis or neoplastic transformation. Dev Dyn 2012 0.81
73 EGFR regulates macrophage activation and function in bacterial infection. J Clin Invest 2016 0.81
74 The deployment of a tissue request tracking system for the CHTN: a case study in managing change in informatics for biobanking operations. BMC Med Inform Decis Mak 2010 0.80
75 IL-33 Signaling Protects from Murine Oxazolone Colitis by Supporting Intestinal Epithelial Function. Inflamm Bowel Dis 2015 0.79
76 KSR1 protects from interleukin-10 deficiency-induced colitis in mice by suppressing T-lymphocyte interferon-γ production. Gastroenterology 2010 0.79
77 The interleukin-17 receptor B subunit is essential for the Th2 response to Helicobacter pylori, but not for control of bacterial burden. PLoS One 2013 0.79
78 Inactivation of the p19(ARF) tumor suppressor affects intestinal epithelial cell proliferation and integrity. J Cell Biochem 2008 0.78
79 Real-time spectroscopic assessment of thermal damage: implications for radiofrequency ablation. J Gastrointest Surg 2004 0.77
80 Dysregulation of E-cadherin by oncogenic Ras in intestinal epithelial cells is blocked by inhibiting MAP kinase. Am J Surg 2003 0.77
81 In vivo assessment of thermal damage in the liver using optical spectroscopy. J Biomed Opt 2004 0.77
82 Four jointed box 1 promotes angiogenesis and is associated with poor patient survival in colorectal carcinoma. PLoS One 2013 0.76
83 Erratum: Dietary zinc alters the microbiota and decreases resistance to Clostridium difficile infection. Nat Med 2016 0.76
84 [(18)F]-FLT PET to predict early response to neoadjuvant therapy in KRAS wild-type rectal cancer: a pilot study. Ann Nucl Med 2015 0.75