Published in Postgrad Med J on August 01, 2006
Mechanisms of cardiovascular remodeling in hyperhomocysteinemia. Antioxid Redox Signal (2011) 1.16
B-vitamins, homocysteine and gene polymorphism in adults with fasting or post-methionine loading hyperhomocysteinemia. Eur J Nutr (2008) 0.75
Assessment of arterial distensibility by automatic pulse wave velocity measurement. Validation and clinical application studies. Hypertension (1995) 4.83
Hyperhomocyst(e)inemia is associated with impaired endothelium-dependent vasodilation in humans. Circulation (1997) 2.00
The oxidant stress of hyperhomocyst(e)inemia. J Clin Invest (1996) 1.76
Homocysteine and cardiovascular disease: current evidence and future prospects. Am J Med (2002) 1.72
Promotion of vascular smooth muscle cell growth by homocysteine: a link to atherosclerosis. Proc Natl Acad Sci U S A (1994) 1.66
Role of oxidant stress in endothelial dysfunction produced by experimental hyperhomocyst(e)inemia in humans. Circulation (1999) 1.44
Impairment of endothelial functions by acute hyperhomocysteinemia and reversal by antioxidant vitamins. JAMA (1999) 1.42
Demonstration of rapid onset vascular endothelial dysfunction after hyperhomocysteinemia: an effect reversible with vitamin C therapy. Circulation (1999) 1.41
Hyperhomocysteinemia after an oral methionine load acutely impairs endothelial function in healthy adults. Circulation (1998) 1.22
ACP Broadsheet No 152: March 1998. Clinical implications of plasma homocysteine measurement in cardiovascular disease. J Clin Pathol (1998) 0.99
Physiological increments in plasma homocysteine induce vascular endothelial dysfunction in normal human subjects. Arterioscler Thromb Vasc Biol (1999) 0.98
Acute methionine loading does not alter arterial stiffness in humans. J Cardiovasc Pharmacol (2001) 0.87
Alternative strategies for stroke care: a prospective randomised controlled trial. Lancet (2000) 3.27
Age-related changes in pharmacokinetics and pharmacodynamics: basic principles and practical applications. Br J Clin Pharmacol (2004) 3.23
Meeting the challenge of prescribing and administering medicines safely: structured teaching and assessment for final year medical students. Med Educ (2003) 2.33
Neuromuscular and psychomotor function in elderly subjects who fall and the relationship with vitamin D status. J Bone Miner Res (2002) 1.83
The implications of a growing evidence base for drug use in elderly patients Part 2. ACE inhibitors and angiotensin receptor blockers in heart failure and high cardiovascular risk patients. Br J Clin Pharmacol (2006) 1.43
Aspartame pharmacokinetics - the effect of ageing. Age Ageing (1996) 1.37
Optimization of drug prescribing. Br J Clin Pharmacol (2004) 1.35
Folic acid enhances endothelial function and reduces blood pressure in smokers: a randomized controlled trial. J Intern Med (2002) 1.23
Development of prescribing indicators for elderly medical inpatients. Br J Clin Pharmacol (1997) 1.13
ACE inhibition: postsynaptic adrenergic sympatholytic action in men. Circulation (1997) 1.07
Antipyrine disposition and liver size in the elderly. Eur J Clin Pharmacol (1978) 1.05
Impaired nitric oxide-mediated vasodilatation and total body nitric oxide production in healthy old age. Clin Sci (Lond) (1997) 1.03
Age-related neural activity during allocentric spatial memory. Memory (2009) 1.01
The use of over-the-counter medication by elderly medical in-patients. Postgrad Med J (1997) 0.99
Hypertension and sensorimotor peripheral neuropathy in type 2 diabetes. Eur Neurol (2006) 0.97
Validity and sensitivity of visual analogue scales in young and older healthy subjects. Age Ageing (1998) 0.96
Predictors of falls in a high risk population: results from the prevention of falls in the elderly trial (PROFET). Emerg Med J (2003) 0.94
Heart rate-dependent stiffening of large arteries in intact and sympathectomized rats. Hypertension (1999) 0.92
Impaired radial artery compliance in normotensive subjects with familial hypercholesterolemia. Atherosclerosis (1996) 0.91
Postural instability as a measure of sedative drug response. Br J Clin Pharmacol (1984) 0.89
Functional magnetic resonance imaging of odor identification: the effect of aging. J Gerontol A Biol Sci Med Sci (2001) 0.88
The cardiovascular system. Br J Clin Pharmacol (2003) 0.88
The association of age with gastric emptying. Age Ageing (1993) 0.87
Responsiveness to oral diazepam in the elderly: relationship to total and free plasma concentrations. Br J Clin Pharmacol (1985) 0.87
Single dose pharmacokinetics and pharmacodynamics of oral loprazolam in the elderly. Br J Clin Pharmacol (1985) 0.85
The implications of a growing evidence base for drug use in elderly patients. Part 1. Statins for primary and secondary cardiovascular prevention. Br J Clin Pharmacol (2006) 0.84
Acute effects of smoking on radial artery compliance in humans. J Hypertens (1994) 0.84
Serum cystatin C is not a better marker of creatinine or digoxin clearance than serum creatinine. Br J Clin Pharmacol (2002) 0.83
A comparison of the central nervous system effects of caffeine and theophylline in elderly subjects. Br J Clin Pharmacol (1991) 0.83
Vascular and blood pressure effects of folic acid in older patients with cardiovascular disease. J Am Geriatr Soc (2001) 0.83
National sentinel clinical audit of evidence-based prescribing for older people: methodology and development. J Eval Clin Pract (2002) 0.82
Side-effect 'tolerance' in elderly long-term recipients of benzodiazepine hypnotics. Age Ageing (1984) 0.82
Development of an indicator to identify inappropriate use of benzodiazepines in elderly medical in-patients. Int J Geriatr Psychiatry (2000) 0.82
The implications of a growing evidence base for drug use in elderly patients. Part 3. Beta-adrenoceptor blockers in heart failure and thrombolytics in acute myocardial infarction. Br J Clin Pharmacol (2006) 0.81
Premedication for bronchoscopy in older patients: a double-blind comparison of two regimens. Respir Med (2005) 0.81
Alpha 1-blocking properties of carvedilol during acute and chronic administration. J Cardiovasc Pharmacol (1992) 0.81
Alterations of radial artery compliance in patients with congestive heart failure. Am J Cardiol (1995) 0.81
Psychomotor performance in elderly hypertensive patients. J Hum Hypertens (1993) 0.81
The implications of a growing evidence base for drug use in elderly patients. Part 4. Vitamin D and bisphosphonates for fractures and osteoporosis. Br J Clin Pharmacol (2006) 0.81
Combined effects of hypertension and hypercholesterolemia on radial artery function. Hypertension (1997) 0.81
National clinical sentinel audit of evidence-based prescribing for older people. J Eval Clin Pract (2004) 0.80
Changes in arterial compliance induced by physical training in hammer-throwers. J Hypertens Suppl (1992) 0.80
Cardiovascular, sedative and anticholinergic effects of amitriptyline and zimelidine in young and elderly volunteers. Acta Psychiatr Scand Suppl (1981) 0.80
Large and medium sized artery abnormalities in untreated and treated hypothyroidism. Eur Heart J (1997) 0.79
Ibuprofen stereochemistry: double-the-trouble? Enantiomer (1999) 0.79
Effects of caffeine on vigilance and other performance tests in normal subjects. J Psychopharmacol (1988) 0.79
Stereoselectivity of ibuprofen metabolism and pharmacokinetics following the administration of the racemate to healthy volunteers. Xenobiotica (2002) 0.78
Predictors of impaired blood pressure homeostasis during acute and sustained orthostasis in patients with type 2 diabetes. Panminerva Med (2006) 0.78
Alterations in working memory networks in amnestic mild cognitive impairment. Neuropsychol Dev Cogn B Aging Neuropsychol Cogn (2014) 0.78
Angiotensin-converting enzyme inhibition and radial artery compliance in patients with congestive heart failure. Hypertension (1995) 0.78
Twenty-four-hour ambulatory blood pressure monitoring in healthy elderly people: reference values. Age Ageing (1995) 0.78
Effects of isolated systolic hypertension and essential hypertension on large and middle-sized artery compliance. Blood Press (1998) 0.78
Profound weight loss associated with reboxetine use in a 44-year-old woman. Br J Clin Pharmacol (2005) 0.77
Evaluation of arterial compliance in humans. Clin Exp Hypertens (1996) 0.77
Effect of antihypertensive treatment on psychomotor performance in the elderly. J Hum Hypertens (1993) 0.77
Plasma concentrations of oral hypoglycaemic drugs in diabetic clinic patients [proceedings]. Br J Clin Pharmacol (1979) 0.77
Stroke, dementia, and drug delivery. Br J Clin Pharmacol (2004) 0.77
Investigation of ambulatory blood pressure monitoring data editing criteria. J Hum Hypertens (1995) 0.77
Differential alterations of common carotid and femoral artery distensibility in 12-week-old spontaneously hypertensive rats. J Hypertens (1997) 0.77
Prokinetic therapy with erythromycin has no significant impact on blood pressure and heart rate in critically ill patients. Br J Clin Pharmacol (2007) 0.77
Cardiac and vascular structural changes in normotensive subjects with parental hypertension. J Hypertens (1995) 0.77
Acute effects of haemodialysis on biochemical modulators of endothelial function. J Intern Med (2007) 0.77
Adenosine-induced respiratory and heart rate changes in young and elderly adults. Br J Clin Pharmacol (1989) 0.77
Acute effects of 5-methyltetrahydrofolate on endothelial function and asymmetric dimethylarginine in patients with chronic heart failure. Nutr Metab Cardiovasc Dis (2009) 0.76
Stereospecific analysis of the major metabolites of ibuprofen in urine by sequential achiral-chiral high-performance liquid chromatography. J Chromatogr B Biomed Sci Appl (1997) 0.76
Psychomotor performance and antihypertensive treatment. Br J Clin Pharmacol (1994) 0.76
Assessment of changes in psychomotor performance of elderly subjects. Br J Clin Pharmacol (1993) 0.75
Computerised psychomotor performance testing: a comparative study of the single dose pharmacodynamics of minaprine and amitriptyline in young and elderly subjects. Br J Clin Pharmacol (1993) 0.75
An unusual case of pneumonia. Int J Clin Pract (2003) 0.75
The use of the Tempa.Dot thermometer in routine clinical practice. Age Ageing (2005) 0.75
Arterial compliance in familial hypercholesterolaemia: a preliminary report. J Hypertens Suppl (1993) 0.75
Drug treatment in the elderly. Practitioner (1987) 0.75
Electrophysiological and clinical study of type-2 diabetic patients with short duration of disease and normal generalized nerve conductions. Panminerva Med (2011) 0.75
ACE inhibitor-based treatment and antihypertensive effects in patients with type 2 diabetes. Panminerva Med (2008) 0.75
High rate of neoplasia and other co-morbid conditions in type-2 diabetic patients with longer duration of disease and poor metabolic control. Panminerva Med (2003) 0.75
Clinical pharmacology in the elderly. Scott Med J (1979) 0.75
Selective AT1 receptor antagonism enhances sympathetically mediated vasoconstriction in man. Clin Pharmacol Ther (2007) 0.75
The pharmacokinetics of paroxetine in the elderly. Acta Psychiatr Scand Suppl (1989) 0.75
Antithyroid effect of chlorpropamide? Hum Toxicol (1983) 0.75
Psychomotor performance: investigating the dose-response relationship for caffeine and theophylline in elderly volunteers. Eur J Clin Pharmacol (1998) 0.75
Pulse pressure is independently associated with sensorimotor peripheral neuropathy in patients with type 2 diabetes. J Intern Med (2005) 0.75
Hypoalbuminaemia and impaired renal function are associated with increased anticholinergic drug prescribing. Int J Clin Pract (2009) 0.75
Nutritional supplementation in community-dwelling elderly people. Ann Nutr Metab (2008) 0.75
Relative preservation of the renin-angiotensin-aldosterone system response to active orthostatism in type 2 diabetic patients with autonomic neuropathy and postural hypotension. Scand J Clin Lab Invest (2003) 0.75
Peripheral blood CD8+ T-cell profiles in patients with psoriatic arthritis: a cross-sectional case-control study. Eur Rev Med Pharmacol Sci (2017) 0.75
Special problems relating to the use of hypnotics in the elderly. Acta Psychiatr Scand Suppl (1986) 0.75
Hawksley random zero sphygmomanometer versus the standard sphygmomanometer: an investigation of mechanisms. J Hum Hypertens (1995) 0.75
A refractory case of vasovagal syncope treated with theophylline. Clin Auton Res (2003) 0.75
Disposition of flurbiprofen in man: influence of stereochemistry and age. Xenobiotica (2003) 0.75
Neuropsychological test performance as an indicator of silent cerebrovascular disease in elderly hypertensives. Age Ageing (1994) 0.75
Comparative assessment of enprofylline and theophylline for chronic obstructive airways disease in the elderly. Respir Med (1990) 0.75
Significance of single serum urate estimations in acutely hospitalized elderly patients. Age Ageing (1987) 0.75