Regulation of cell-cell junctions by the cytoskeleton.

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Cadherins and cancer: how does cadherin dysfunction promote tumor progression? Oncogene (2008) 3.63

Mechanical tugging force regulates the size of cell-cell junctions. Proc Natl Acad Sci U S A (2010) 3.44

Epithelial cell polarity, stem cells and cancer. Nat Rev Cancer (2011) 3.06

EPLIN mediates linkage of the cadherin catenin complex to F-actin and stabilizes the circumferential actin belt. Proc Natl Acad Sci U S A (2007) 2.82

Catenins: keeping cells from getting their signals crossed. Dev Cell (2006) 2.70

Myosin VI and vinculin cooperate during the morphogenesis of cadherin cell cell contacts in mammalian epithelial cells. J Cell Biol (2007) 2.02

Intercellular junction assembly, dynamics, and homeostasis. Cold Spring Harb Perspect Biol (2010) 1.96

N-WASP regulates the epithelial junctional actin cytoskeleton through a non-canonical post-nucleation pathway. Nat Cell Biol (2011) 1.92

TLR2-induced calpain cleavage of epithelial junctional proteins facilitates leukocyte transmigration. Cell Host Microbe (2009) 1.87

Molecular bases of cell-cell junctions stability and dynamics. Cold Spring Harb Perspect Biol (2009) 1.78

A unique role for nonmuscle myosin heavy chain IIA in regulation of epithelial apical junctions. PLoS One (2007) 1.72

Spontaneous assembly and active disassembly balance adherens junction homeostasis. Proc Natl Acad Sci U S A (2010) 1.59

miR-17 family of microRNAs controls FGF10-mediated embryonic lung epithelial branching morphogenesis through MAPK14 and STAT3 regulation of E-Cadherin distribution. Dev Biol (2009) 1.56

Engineering microscale topographies to control the cell-substrate interface. Biomaterials (2012) 1.51

Rho/Rho-associated kinase-II signaling mediates disassembly of epithelial apical junctions. Mol Biol Cell (2007) 1.50

Stable and unstable cadherin dimers: mechanisms of formation and roles in cell adhesion. Mol Biol Cell (2007) 1.42

Relaxing the actin cytoskeleton for adhesion and movement with Ena/VASP. J Cell Biol (2008) 1.34

Vascular endothelial-cadherin stabilizes at cell-cell junctions by anchoring to circumferential actin bundles through alpha- and beta-catenins in cyclic AMP-Epac-Rap1 signal-activated endothelial cells. Mol Biol Cell (2009) 1.33

Multicellular dynamics during epithelial elongation. Semin Cell Dev Biol (2008) 1.27

Loss of RhoA in neural progenitor cells causes the disruption of adherens junctions and hyperproliferation. Proc Natl Acad Sci U S A (2011) 1.26

Binding to F-actin guides cadherin cluster assembly, stability, and movement. J Cell Biol (2013) 1.23

α-Actinin-4/FSGS1 is required for Arp2/3-dependent actin assembly at the adherens junction. J Cell Biol (2012) 1.22

Contact-dependent promotion of cell migration by the OL-protocadherin-Nap1 interaction. J Cell Biol (2008) 1.21

Substrate viscosity enhances correlation in epithelial sheet movement. Biophys J (2011) 1.21

Cytoskeletal dynamics and spermatogenesis. Philos Trans R Soc Lond B Biol Sci (2010) 1.19

Actin polymerization is essential for myelin sheath fragmentation during Wallerian degeneration. J Neurosci (2011) 1.17

α-Catenin and vinculin cooperate to promote high E-cadherin-based adhesion strength. J Biol Chem (2012) 1.14

The Drosophila CD2AP/CIN85 orthologue Cindr regulates junctions and cytoskeleton dynamics during tissue patterning. J Cell Biol (2008) 1.11

Intercellular and extracellular mechanotransduction in cardiac myocytes. Pflugers Arch (2011) 1.11

VASP involvement in force-mediated adherens junction strengthening. Biochem Biophys Res Commun (2008) 1.09

Ajuba is required for Rac activation and maintenance of E-cadherin adhesion. J Cell Biol (2011) 1.08

The TRPV4 channel contributes to intercellular junction formation in keratinocytes. J Biol Chem (2010) 1.07

Zyxin emerges as a key player in the mechanotransduction at cell adhesive structures. Commun Integr Biol (2008) 1.06

Conserved F-actin dynamics and force transmission at cell adhesions. Curr Opin Cell Biol (2010) 1.06

PLEKHA7 is an adherens junction protein with a tissue distribution and subcellular localization distinct from ZO-1 and E-cadherin. PLoS One (2010) 1.03

The motor protein myosin-X transports VE-cadherin along filopodia to allow the formation of early endothelial cell-cell contacts. Mol Cell Biol (2010) 1.03

Cardiac myocyte remodeling mediated by N-cadherin-dependent mechanosensing. Am J Physiol Heart Circ Physiol (2011) 1.02

Tara up-regulates E-cadherin transcription by binding to the Trio RhoGEF and inhibiting Rac signaling. J Cell Biol (2011) 1.02

Involvement of actinin-4 in the recruitment of JRAB/MICAL-L2 to cell-cell junctions and the formation of functional tight junctions. Mol Cell Biol (2008) 0.97

Multicomponent analysis of junctional movements regulated by myosin II isoforms at the epithelial zonula adherens. PLoS One (2011) 0.97

Cortactin is a functional target of E-cadherin-activated Src family kinases in MCF7 epithelial monolayers. J Biol Chem (2009) 0.95

Golgi-associated cPLA2alpha regulates endothelial cell-cell junction integrity by controlling the trafficking of transmembrane junction proteins. Mol Biol Cell (2009) 0.95

Nonredundant roles of cytoplasmic β- and γ-actin isoforms in regulation of epithelial apical junctions. Mol Biol Cell (2012) 0.94

Contribution of annexin 2 to the architecture of mature endothelial adherens junctions. Mol Cell Biol (2007) 0.94

The actin-binding protein profilin is required for germline stem cell maintenance and germ cell enclosure by somatic cyst cells. Development (2014) 0.92

N-glycosylation status of E-cadherin controls cytoskeletal dynamics through the organization of distinct β-catenin- and γ-catenin-containing AJs. Cell Health Cytoskelet (2009) 0.91

Formation and disassembly of adherens and tight junctions in the corneal endothelium: regulation by actomyosin contraction. Invest Ophthalmol Vis Sci (2009) 0.90

Nuclear signaling from cadherin adhesion complexes. Curr Top Dev Biol (2015) 0.90

An association between type Iγ PI4P 5-kinase and Exo70 directs E-cadherin clustering and epithelial polarization. Mol Biol Cell (2011) 0.90

Ca2+ signaling in airway epithelial cells facilitates leukocyte recruitment and transepithelial migration. J Leukoc Biol (2009) 0.89

α-catenin, vinculin, and F-actin in strengthening E-cadherin cell-cell adhesions and mechanosensing. Cell Adh Migr (2013) 0.89

Talin Dependent Mechanosensitivity of Cell Focal Adhesions. Cell Mol Bioeng (2014) 0.88

Crossroads of integrins and cadherins in epithelia and stroma remodeling. Cell Adh Migr (2012) 0.88

N-cadherin cell-cell adhesion complexes are regulated by fibronectin matrix assembly. J Biol Chem (2010) 0.87

The formation of ordered nanoclusters controls cadherin anchoring to actin and cell-cell contact fluidity. J Cell Biol (2015) 0.87

Regulation of actin dynamics and protein trafficking during spermatogenesis--insights into a complex process. Crit Rev Biochem Mol Biol (2013) 0.86

E-cadherin differentially regulates the assembly of Connexin43 and Connexin32 into gap junctions in human squamous carcinoma cells. J Biol Chem (2010) 0.86

The mechanotransduction machinery at work at adherens junctions. Integr Biol (Camb) (2015) 0.86

Fluid shear, intercellular stress, and endothelial cell alignment. Am J Physiol Cell Physiol (2015) 0.86

c-Src-mediated epithelial cell migration and invasion regulated by PDZ binding site. Mol Cell Biol (2007) 0.85

Subnuclear development of the zebrafish habenular nuclei requires ER translocon function. Dev Biol (2011) 0.85

Anti-oestrogens but not oestrogen deprivation promote cellular invasion in intercellular adhesion-deficient breast cancer cells. Breast Cancer Res (2008) 0.85

N-cadherin sustains motility and polarity of future cortical interneurons during tangential migration. J Neurosci (2013) 0.84

Heart of glass anchors Rasip1 at endothelial cell-cell junctions to support vascular integrity. Elife (2016) 0.83

Tissue stiffness dictates development, homeostasis, and disease progression. Organogenesis (2015) 0.83

N-cadherin and integrin blockade inhibit arteriolar myogenic reactivity but not pressure-induced increases in intracellular Ca. Front Physiol (2010) 0.82

Tension, free space, and cell damage in a microfluidic wound healing assay. PLoS One (2011) 0.82

The TRPV4 cation channel: A molecule linking skin temperature and barrier function. Commun Integr Biol (2010) 0.82

TEM4 is a junctional Rho GEF required for cell-cell adhesion, monolayer integrity and barrier function. J Cell Sci (2013) 0.82

An EMMPRIN-γ-catenin-Nm23 complex drives ATP production and actomyosin contractility at endothelial junctions. J Cell Sci (2014) 0.81

N-cadherin mediates neuronal cell survival through Bim down-regulation. PLoS One (2012) 0.81

F-actin-based extensions of the head cyst cell adhere to the maturing spermatids to maintain them in a tight bundle and prevent their premature release in Drosophila testis. BMC Biol (2009) 0.81

α(E)-catenin regulates BMP-7 expression and migration in renal epithelial cells. Am J Nephrol (2014) 0.81

Different gene-expression profiles for the poorly differentiated carcinoma and the highly differentiated papillary adenocarcinoma in mammary glands support distinct metabolic pathways. BMC Cancer (2008) 0.81

Rho-ROCK and Rac-PAK signaling pathways have opposing effects on the cell-to-cell spread of Marek's Disease Virus. PLoS One (2012) 0.80

Crosstalk between Inflammation and ROCK/MLCK Signaling Pathways in Gastrointestinal Disorders with Intestinal Hyperpermeability. Gastroenterol Res Pract (2016) 0.79

The status of intercellular junctions in established lens epithelial cell lines. Mol Vis (2012) 0.79

α-Catenin-mediated cadherin clustering couples cadherin and actin dynamics. J Cell Biol (2015) 0.79

A mathematical model of alpha-catenin dimerization at adherens junctions in polarized epithelial cells. J Theor Biol (2008) 0.78

Cadherin controls nectin recruitment into adherens junctions by remodeling the actin cytoskeleton. J Cell Sci (2014) 0.78

alpha-Actinin links LPP, but not zyxin, to cadherin-based junctions. Biochem Biophys Res Commun (2008) 0.78

Myosins as fundamental components during tumorigenesis: diverse and indispensable. Oncotarget (2016) 0.78

The focal adhesion protein PINCH-1 associates with EPLIN at integrin adhesion sites. J Cell Sci (2015) 0.77

Neogenin recruitment of the WAVE regulatory complex maintains adherens junction stability and tension. Nat Commun (2016) 0.76

KIF17 regulates RhoA-dependent actin remodeling at epithelial cell-cell adhesions. J Cell Sci (2016) 0.75

A spatiotemporal characterization method for the dynamic cytoskeleton. Cytoskeleton (Hoboken) (2016) 0.75

Molecular Stretching Modulates Mechanosensing Pathways. Protein Sci (2017) 0.75

EPLIN: a fundamental actin regulator in cancer metastasis? Cancer Metastasis Rev (2015) 0.75

Hold on tightly: how to keep the local activation of small GTPases. Cell Adh Migr (2013) 0.75

Glucose transport by epithelia prepared from harvested enterocytes. Cytotechnology (2013) 0.75

A phenomenological model of cell-cell adhesion mediated by cadherins. J Math Biol (2016) 0.75

Endothelial cell SHP-2 negatively regulates neutrophil adhesion and promotes transmigration by enhancing ICAM-1-VE-cadherin interaction. FASEB J (2017) 0.75

In silico characterization of cell-cell interactions using a cellular automata model of cell culture. BMC Res Notes (2017) 0.75

Cigarette smoke disrupts monolayer integrity by altering epithelial cell-cell adhesion and cortical tension. Am J Physiol Lung Cell Mol Physiol (2017) 0.75

Targeted killing of cancer cells in vivo and in vitro with EGF-directed carbon nanotube-based drug delivery. ACS Nano (2009) 2.39

Inhibiting glutamine uptake represents an attractive new strategy for treating acute myeloid leukemia. Blood (2013) 2.38

Measuring patients' perceptions of patient-centered care: a systematic review of tools for family medicine. Ann Fam Med (2011) 2.20

An essential role for Rac1 in endothelial cell function and vascular development. FASEB J (2008) 2.09

Strength dependence of cadherin-mediated adhesions. Biophys J (2010) 1.86

Secreted factors from brain endothelial cells maintain glioblastoma stem-like cell expansion through the mTOR pathway. EMBO Rep (2011) 1.86

Traction forces exerted through N-cadherin contacts. Biol Cell (2006) 1.78

Lamellipodium extension and cadherin adhesion: two cell responses to cadherin activation relying on distinct signalling pathways. J Cell Sci (2003) 1.72

A catalytic-independent role for the LUBAC in NF-κB activation upon antigen receptor engagement and in lymphoma cells. Blood (2014) 1.68

Semaphorin 3E initiates antiangiogenic signaling through plexin D1 by regulating Arf6 and R-Ras. Mol Cell Biol (2010) 1.50

A molecular clutch between the actin flow and N-cadherin adhesions drives growth cone migration. J Neurosci (2008) 1.38

The LKB1/AMPK signaling pathway has tumor suppressor activity in acute myeloid leukemia through the repression of mTOR-dependent oncogenic mRNA translation. Blood (2010) 1.38

Regulation of N-cadherin dynamics at neuronal contacts by ligand binding and cytoskeletal coupling. Mol Biol Cell (2005) 1.29

Recruitment of the kainate receptor subunit glutamate receptor 6 by cadherin/catenin complexes. J Neurosci (2002) 1.25

Plexin-B1 utilizes RhoA and Rho kinase to promote the integrin-dependent activation of Akt and ERK and endothelial cell motility. J Biol Chem (2007) 1.24

Transferrin receptor 2 is a component of the erythropoietin receptor complex and is required for efficient erythropoiesis. Blood (2010) 1.23

Complementary roles of intracellular and pericellular collagen degradation pathways in vivo. Mol Cell Biol (2007) 1.22

Multiple PPPS/TP motifs act in a combinatorial fashion to transduce Wnt signaling through LRP6. FEBS Lett (2007) 1.20

Patient-centered care in chronic disease management: a thematic analysis of the literature in family medicine. Patient Educ Couns (2012) 1.18

Tetanus neurotoxin-mediated cleavage of cellubrevin impairs epithelial cell migration and integrin-dependent cell adhesion. Proc Natl Acad Sci U S A (2005) 1.15

Differential proteomic analysis of human glioblastoma and neural stem cells reveals HDGF as a novel angiogenic secreted factor. Stem Cells (2012) 1.14

N-cadherin activation substitutes for the cell contact control in cell cycle arrest and myogenic differentiation: involvement of p120 and beta-catenin. J Biol Chem (2004) 1.12

Evaluation of iron oxide nanoparticle biocompatibility. Int J Nanomedicine (2011) 1.06

Glioblastoma cell-secreted interleukin-8 induces brain endothelial cell permeability via CXCR2. PLoS One (2012) 1.06

Jumping the barrier: VE-cadherin, VEGF and other angiogenic modifiers in cancer. Biol Cell (2011) 1.03

Vascular permeability and drug delivery in cancers. Front Oncol (2013) 0.99

VE-cadherin and claudin-5: it takes two to tango. Nat Cell Biol (2008) 0.99

Semaphorin 3A elevates endothelial cell permeability through PP2A inactivation. J Cell Sci (2012) 0.98

Clustering of cellular prion protein induces ERK1/2 and stathmin phosphorylation in GT1-7 neuronal cells. FEBS Lett (2004) 0.98

Role of endothelial cell-cell junctions in endothelial permeability. Methods Mol Biol (2011) 0.98

The endoplasmic reticulum acts as a platform for ubiquitylated components of nuclear factor κB signaling. Sci Signal (2013) 0.94

Endothelial permeability and VE-cadherin: a wacky comradeship. Cell Adh Migr (2014) 0.93

PAKing up to the endothelium. Cell Signal (2009) 0.91

A novel function for cadherin-11 in the regulation of motor axon elongation and fasciculation. Mol Cell Neurosci (2005) 0.90

Homoassociation of VE-cadherin follows a mechanism common to "classical" cadherins. J Mol Biol (2003) 0.87

Family physician enabling attitudes: a qualitative study of patient perceptions. BMC Fam Pract (2013) 0.87

Tyrosine phosphorylation of DEP-1/CD148 as a mechanism controlling Src kinase activation, endothelial cell permeability, invasion, and capillary formation. Blood (2012) 0.86

Proteomes of umbilical vein and microvascular endothelial cells reflect distinct biological properties and influence immune recognition. Proteomics (2012) 0.85

Negative regulation of NF-κB signaling in T lymphocytes by the ubiquitin-specific protease USP34. Cell Commun Signal (2013) 0.85

Preeclamptic plasma induces transcription modifications involving the AP-1 transcriptional regulator JDP2 in endothelial cells. Am J Pathol (2013) 0.85

Interplay between BCL10, MALT1 and IkappaBalpha during T-cell-receptor-mediated NFkappaB activation. J Cell Sci (2010) 0.84

Complementary expression and regulation of cadherins 6 and 11 during specific steps of motoneuron differentiation. Mol Cell Neurosci (2002) 0.83

The C-terminus region of β-arrestin1 modulates VE-cadherin expression and endothelial cell permeability. Cell Commun Signal (2013) 0.82

Cadherin-based cell adhesion in neuromuscular development. Biol Cell (2002) 0.80

A dileucine motif targets MCAM-l cell adhesion molecule to the basolateral membrane in MDCK cells. FEBS Lett (2006) 0.79

Critical multiple angiogenic factors secreted by glioblastoma stem-like cells underline the need for combinatorial anti-angiogenic therapeutic strategies. Proteomics Clin Appl (2013) 0.78

Feeding the hungry enemy: an endothelial recipe for glioma stem cells. Cell Cycle (2011) 0.77

Transforming primary healthcare by including the stakeholders involved in delivering care to people living in poverty: EQUIhealThY study protocol. BMC Health Serv Res (2013) 0.77

Physician Enabling Skills Questionnaire: Validation of a newly developed instrument in primary health care. Can Fam Physician (2015) 0.75

Differential effects of Bartonella henselae on human and feline macro- and micro-vascular endothelial cells. PLoS One (2011) 0.75

[Regulation of cell adhesion by the cadherin cytoplasmic domain]. J Soc Biol (2004) 0.75