Published in Proc Natl Acad Sci U S A on April 18, 2011
Llgl1 Connects Cell Polarity with Cell-Cell Adhesion in Embryonic Neural Stem Cells. Dev Cell (2017) 1.39
Neurogenesis during development of the vertebrate central nervous system. EMBO Rep (2014) 1.19
The widely used Wnt1-Cre transgene causes developmental phenotypes by ectopic activation of Wnt signaling. Dev Biol (2013) 1.16
Rho family GTPases: key players in neuronal development, neuronal survival, and neurodegeneration. Front Cell Neurosci (2014) 1.07
Cell biological regulation of division fate in vertebrate neuroepithelial cells. Dev Dyn (2011) 1.02
Wnt9b-dependent FGF signaling is crucial for outgrowth of the nasal and maxillary processes during upper jaw and lip development. Development (2012) 0.96
Deficiency of mDia, an actin nucleator, disrupts integrity of neuroepithelium and causes periventricular dysplasia. PLoS One (2011) 0.94
Cell type-specific signaling function of RhoA GTPase: lessons from mouse gene targeting. J Biol Chem (2013) 0.93
mTOR regulates brain morphogenesis by mediating GSK3 signaling. Development (2014) 0.93
The interdependence of the Rho GTPases and apicobasal cell polarity. Small GTPases (2014) 0.91
Rnd3 coordinates early steps of cortical neurogenesis through actin-dependent and -independent mechanisms. Nat Commun (2013) 0.91
RhoA of the Rho family small GTPases is essential for B lymphocyte development. PLoS One (2012) 0.89
Immunoprotective properties of primary Sertoli cells in mice: potential functional pathways that confer immune privilege. Biol Reprod (2012) 0.88
RhoA is dispensable for axon guidance of sensory neurons in the mouse dorsal root ganglia. Front Mol Neurosci (2012) 0.88
Cytoskeletal proteins in cortical development and disease: actin associated proteins in periventricular heterotopia. Front Cell Neurosci (2015) 0.86
Subnuclear development of the zebrafish habenular nuclei requires ER translocon function. Dev Biol (2011) 0.85
Left-right locomotor circuitry depends on RhoA-driven organization of the neuroepithelium in the developing spinal cord. J Neurosci (2012) 0.85
DNA methyltransferase 3b is dispensable for mouse neural crest development. PLoS One (2012) 0.83
RhoA orchestrates glycolysis for TH2 cell differentiation and allergic airway inflammation. J Allergy Clin Immunol (2015) 0.82
Pathway analysis in attention deficit hyperactivity disorder: An ensemble approach. Am J Med Genet B Neuropsychiatr Genet (2016) 0.81
Deletion of Sema3a or plexinA1/plexinA3 causes defects in sensory afferent projections of statoacoustic ganglion neurons. PLoS One (2013) 0.80
RhoA and Cdc42 are required in pre-migratory progenitors of the medial ganglionic eminence ventricular zone for proper cortical interneuron migration. Development (2013) 0.80
Small Rho-GTPases and cortical malformations: fine-tuning the cytoskeleton stability. Small GTPases (2013) 0.79
Ameloblasts require active RhoA to generate normal dental enamel. Eur J Oral Sci (2013) 0.79
Rho GTPases in embryonic development. Small GTPases (2014) 0.79
Regulation of cerebral cortex development by Rho GTPases: insights from in vivo studies. Front Cell Neurosci (2015) 0.78
Epithelial-Mesenchymal Transitions during Neural Crest and Somite Development. J Clin Med (2015) 0.78
ArhGEF18 regulated Rho signaling in vertebrate retina development. Small GTPases (2013) 0.78
The small GTPases RhoA and Rac1 regulate cerebellar development by controlling cell morphogenesis, migration and foliation. Dev Biol (2014) 0.78
EZH2 regulates neuroepithelium structure and neuroblast proliferation by repressing p21. Open Biol (2016) 0.78
Angiogenesis in the developing spinal cord: blood vessel exclusion from neural progenitor region is mediated by VEGF and its antagonists. PLoS One (2015) 0.77
Molecular mechanisms of midfacial developmental defects. Dev Dyn (2015) 0.75
Brain size is controlled by the mammalian target of rapamycin (mTOR) in mice. Commun Integr Biol (2015) 0.75
The hominoid-specific gene TBC1D3 promotes generation of basal neural progenitors and induces cortical folding in mice. Elife (2016) 0.75
Deletion of RhoA in progesterone receptor expressing cells leads to luteal insufficiency and infertility in female mice. Endocrinology (2017) 0.75
Loss of Usp9x disrupts cell adhesion, and components of the Wnt and Notch signaling pathways in neural progenitors. Sci Rep (2017) 0.75
Cytoskeletal Stability in the Auditory Organ In Vivo: RhoA Is Dispensable for Wound Healing but Essential for Hair Cell Development. eNeuro (2017) 0.75
Mammalian Rho GTPases: new insights into their functions from in vivo studies. Nat Rev Mol Cell Biol (2008) 8.99
Regulation of cerebral cortical size by control of cell cycle exit in neural precursors. Science (2002) 7.92
Evolution of the neocortex: a perspective from developmental biology. Nat Rev Neurosci (2009) 5.51
SOX2, a persistent marker for multipotential neural stem cells derived from embryonic stem cells, the embryo or the adult. Dev Neurosci (2005) 4.48
Targeting of cre to the Foxg1 (BF-1) locus mediates loxP recombination in the telencephalon and other developing head structures. Dev Biol (2000) 4.03
Adherens junctions: from molecules to morphogenesis. Nat Rev Mol Cell Biol (2010) 3.97
Localized zones of Rho and Rac activities drive initiation and expansion of epithelial cell-cell adhesion. J Cell Biol (2007) 3.76
Numb and Numbl are required for maintenance of cadherin-based adhesion and polarity of neural progenitors. Nat Neurosci (2007) 3.13
alphaE-catenin controls cerebral cortical size by regulating the hedgehog signaling pathway. Science (2006) 3.09
The Rho-GTPase cdc42 regulates neural progenitor fate at the apical surface. Nat Neurosci (2006) 2.87
RhoC is dispensable for embryogenesis and tumor initiation but essential for metastasis. Genes Dev (2005) 2.59
Loss of cell polarity causes severe brain dysplasia in Lgl1 knockout mice. Genes Dev (2004) 2.55
Regulation of cell-cell junctions by the cytoskeleton. Curr Opin Cell Biol (2006) 2.53
Rho1 interacts with p120ctn and alpha-catenin, and regulates cadherin-based adherens junction components in Drosophila. Development (2002) 2.37
Hedgehog-GLI signaling regulates the behavior of cells with stem cell properties in the developing neocortex. Development (2003) 2.26
N-cadherin mediates cortical organization in the mouse brain. Dev Biol (2006) 2.19
Hedgehog-Gli signalling and the growth of the brain. Nat Rev Neurosci (2002) 2.10
RhoB is dispensable for mouse development, but it modifies susceptibility to tumor formation as well as cell adhesion and growth factor signaling in transformed cells. Mol Cell Biol (2001) 1.99
Role of beta-catenin in the developing cortical and hippocampal neuroepithelium. Neuroscience (2003) 1.78
Inactivation of Numb and Numblike in embryonic dorsal forebrain impairs neurogenesis and disrupts cortical morphogenesis. Neuron (2003) 1.73
The cell biology of neural stem and progenitor cells and its significance for their proliferation versus differentiation during mammalian brain development. Curr Opin Cell Biol (2008) 1.63
Cdc42 deficiency causes Sonic hedgehog-independent holoprosencephaly. Proc Natl Acad Sci U S A (2006) 1.53
Adhesive and signaling functions of cadherins and catenins in vertebrate development. Cold Spring Harb Perspect Biol (2009) 1.52
The role of cell death in regulating the size and shape of the mammalian forebrain. Cereb Cortex (1999) 1.46
Visualization of embryonic neural stem cells using Hes promoters in transgenic mice. Mol Cell Neurosci (2005) 1.41
RhoA is dispensable for skin development, but crucial for contraction and directed migration of keratinocytes. Mol Biol Cell (2011) 1.39
Regulation of epithelial apical junctional complex by Rho family GTPases. Front Biosci (Landmark Ed) (2009) 1.34
Drosophila RhoA regulates the cytoskeleton and cell-cell adhesion in the developing epidermis. Development (2002) 1.31
Rac1 controls the formation of midline commissures and the competency of tangential migration in ventral telencephalic neurons. J Neurosci (2007) 1.25
Differences in cyclin D2 and D1 protein expression distinguish forebrain progenitor subsets. Cereb Cortex (2006) 1.09
Manipulating gene activity in Wnt1-expressing precursors of neural epithelial and neural crest cells. Dev Dyn (2010) 0.99
Molecular control of brain size: regulators of neural stem cell life, death and beyond. Exp Cell Res (2010) 0.87
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy (2007) 20.92
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
In vivo depletion of CD11c+ dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens. Immunity (2002) 14.57
Roll-to-roll production of 30-inch graphene films for transparent electrodes. Nat Nanotechnol (2010) 12.59
Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation. Dev Cell (2005) 7.64
Rational design and characterization of a Rac GTPase-specific small molecule inhibitor. Proc Natl Acad Sci U S A (2004) 7.24
Cbfa1-independent decrease in osteoblast proliferation, osteopenia, and persistent embryonic eye vascularization in mice deficient in Lrp5, a Wnt coreceptor. J Cell Biol (2002) 6.20
Genetic manipulation of periostin expression reveals a role in cardiac hypertrophy and ventricular remodeling. Circ Res (2007) 4.53
A distinct macrophage population mediates metastatic breast cancer cell extravasation, establishment and growth. PLoS One (2009) 3.86
Microenvironment determines lineage fate in a human model of MLL-AF9 leukemia. Cancer Cell (2008) 3.79
WNT7b mediates macrophage-induced programmed cell death in patterning of the vasculature. Nature (2005) 3.44
Rho GTPase-activating proteins in cell regulation. Trends Cell Biol (2003) 3.44
Angiopoietin-2 displays VEGF-dependent modulation of capillary structure and endothelial cell survival in vivo. Proc Natl Acad Sci U S A (2002) 3.25
Cerebral ischemia-hypoxia induces intravascular coagulation and autophagy. Am J Pathol (2006) 3.18
Shearwave dispersion ultrasound vibrometry (SDUV) for measuring tissue elasticity and viscosity. IEEE Trans Ultrason Ferroelectr Freq Control (2009) 3.00
Semaphorin 3E and plexin-D1 control vascular pattern independently of neuropilins. Science (2004) 2.95
Compact biocompatible quantum dots functionalized for cellular imaging. J Am Chem Soc (2008) 2.92
Nuclear targeting of Akt enhances kinase activity and survival of cardiomyocytes. Circ Res (2004) 2.91
Macrophage Wnt7b is critical for kidney repair and regeneration. Proc Natl Acad Sci U S A (2010) 2.87
High-throughput illumina strand-specific RNA sequencing library preparation. Cold Spring Harb Protoc (2011) 2.72
Monovalent, reduced-size quantum dots for imaging receptors on living cells. Nat Methods (2008) 2.68
Enamines as novel antibacterials and their structure-activity relationships. Eur J Med Chem (2007) 2.65
Anterior pedicle screw fixation of C2: an anatomic analysis of axis morphology and simulated surgical fixation. Eur Spine J (2014) 2.64
Rac GTPases differentially integrate signals regulating hematopoietic stem cell localization. Nat Med (2005) 2.63
A canonical to non-canonical Wnt signalling switch in haematopoietic stem-cell ageing. Nature (2013) 2.62
Cdc42 activity regulates hematopoietic stem cell aging and rejuvenation. Cell Stem Cell (2012) 2.60
Conditional macrophage ablation demonstrates that resident macrophages initiate acute peritoneal inflammation. J Immunol (2005) 2.50
A cost-effective method for Illumina small RNA-Seq library preparation using T4 RNA ligase 1 adenylated adapters. Plant Methods (2012) 2.46
Single-base resolution methylomes of tomato fruit development reveal epigenome modifications associated with ripening. Nat Biotechnol (2013) 2.43
The draft genome of watermelon (Citrullus lanatus) and resequencing of 20 diverse accessions. Nat Genet (2012) 2.33
T lymphocytes potentiate endogenous neuroprotective inflammation in a mouse model of ALS. Proc Natl Acad Sci U S A (2008) 2.26
Nrarp coordinates endothelial Notch and Wnt signaling to control vessel density in angiogenesis. Dev Cell (2009) 2.17
A Rac-cGMP signaling pathway. Cell (2007) 2.16
An essential role for Rac1 in endothelial cell function and vascular development. FASEB J (2008) 2.09
Signaling and cytoskeletal requirements in erythroblast enucleation. Blood (2012) 2.05
A direct and melanopsin-dependent fetal light response regulates mouse eye development. Nature (2013) 1.98
Ctip2 controls the differentiation of medium spiny neurons and the establishment of the cellular architecture of the striatum. J Neurosci (2008) 1.97
Gene targeting of Cdc42 and Cdc42GAP affirms the critical involvement of Cdc42 in filopodia induction, directed migration, and proliferation in primary mouse embryonic fibroblasts. Mol Biol Cell (2006) 1.96
Association of HTRA1 mutations and familial ischemic cerebral small-vessel disease. N Engl J Med (2009) 1.96
Regulation of angiogenesis by a non-canonical Wnt-Flt1 pathway in myeloid cells. Nature (2011) 1.91
Specificity of sensory-motor connections encoded by Sema3e-Plxnd1 recognition. Nature (2009) 1.88
Transcriptome sequencing and comparative analysis of cucumber flowers with different sex types. BMC Genomics (2010) 1.88
Tissue- and cell-type specific transcriptome profiling of expanding tomato fruit provides insights into metabolic and regulatory specialization and cuticle formation. Plant Cell (2011) 1.88
VKORC1 haplotypes are associated with arterial vascular diseases (stroke, coronary heart disease, and aortic dissection). Circulation (2006) 1.86
Wntless functions in mature osteoblasts to regulate bone mass. Proc Natl Acad Sci U S A (2012) 1.85
Gating of Sema3E/PlexinD1 signaling by neuropilin-1 switches axonal repulsion to attraction during brain development. Neuron (2007) 1.83
Conditional rhythmicity of ventral spinal interneurons defined by expression of the Hb9 homeodomain protein. J Neurosci (2005) 1.76
The duality of beta-catenin function: a requirement in lens morphogenesis and signaling suppression of lens fate in periocular ectoderm. Dev Biol (2005) 1.74
Rho GTPase Cdc42 coordinates hematopoietic stem cell quiescence and niche interaction in the bone marrow. Proc Natl Acad Sci U S A (2007) 1.74
Transjugular intrahepatic portosystemic shunt versus endoscopic therapy in the secondary prophylaxis of variceal rebleeding in cirrhotic patients: meta-analysis update. J Clin Gastroenterol (2008) 1.74
Rac guanosine triphosphatases represent integrating molecular therapeutic targets for BCR-ABL-induced myeloproliferative disease. Cancer Cell (2007) 1.72
Cdc42 regulates bone modeling and remodeling in mice by modulating RANKL/M-CSF signaling and osteoclast polarization. J Clin Invest (2010) 1.71
Decoding of polymodal sensory stimuli by postsynaptic glutamate receptors in C. elegans. Neuron (2002) 1.70
Genetic deletion of Rac1 GTPase reveals its critical role in actin stress fiber formation and focal adhesion complex assembly. J Biol Chem (2006) 1.66
Semaphorin 3E-Plexin-D1 signaling regulates VEGF function in developmental angiogenesis via a feedback mechanism. Genes Dev (2011) 1.63
Expression of seven main Rho family members in gastric carcinoma. Biochem Biophys Res Commun (2004) 1.63
Cdc42 coordinates proliferation, polarity, migration, and differentiation of small intestinal epithelial cells in mice. Gastroenterology (2013) 1.62
Interplay of mevalonate and Hippo pathways regulates RHAMM transcription via YAP to modulate breast cancer cell motility. Proc Natl Acad Sci U S A (2013) 1.57
Localization of Rac2 via the C terminus and aspartic acid 150 specifies superoxide generation, actin polarity and chemotaxis in neutrophils. Nat Immunol (2004) 1.56
Generation of mice with a conditional null allele for Wntless. Genesis (2010) 1.55
miR-137 targets Cdc42 expression, induces cell cycle G1 arrest and inhibits invasion in colorectal cancer cells. Int J Cancer (2011) 1.53
Sema3A regulates bone-mass accrual through sensory innervations. Nature (2013) 1.53
Cdc42 deficiency causes Sonic hedgehog-independent holoprosencephaly. Proc Natl Acad Sci U S A (2006) 1.53
Co-operative roles for E-cadherin and N-cadherin during lens vesicle separation and lens epithelial cell survival. Dev Biol (2008) 1.53
ARAP1: a point of convergence for Arf and Rho signaling. Mol Cell (2002) 1.53
Homo- and hetero-oligomerization of PDZ-RhoGEF, LARG and p115RhoGEF by their C-terminal region regulates their in vivo Rho GEF activity and transforming potential. Oncogene (2004) 1.52
Genetic deletion of Cdc42GAP reveals a role of Cdc42 in erythropoiesis and hematopoietic stem/progenitor cell survival, adhesion, and engraftment. Blood (2005) 1.52
LRP-6 is a coreceptor for multiple fibrogenic signaling pathways in pericytes and myofibroblasts that are inhibited by DKK-1. Proc Natl Acad Sci U S A (2013) 1.51
Rac1 is essential in cocaine-induced structural plasticity of nucleus accumbens neurons. Nat Neurosci (2012) 1.50
Cdc42 in oncogenic transformation, invasion, and tumorigenesis. Cell Signal (2011) 1.50
p19Arf-p53 tumor suppressor pathway regulates cell motility by suppression of phosphoinositide 3-kinase and Rac1 GTPase activities. J Biol Chem (2003) 1.49
Nestin-CreER mice reveal DNA synthesis by nonapoptotic neurons following cerebral ischemia hypoxia. Cereb Cortex (2007) 1.48
p250GAP, a novel brain-enriched GTPase-activating protein for Rho family GTPases, is involved in the N-methyl-d-aspartate receptor signaling. Mol Biol Cell (2003) 1.48
Two distinct roles of mitogen-activated protein kinases in platelets and a novel Rac1-MAPK-dependent integrin outside-in retractile signaling pathway. Blood (2008) 1.47
Obligatory participation of macrophages in an angiopoietin 2-mediated cell death switch. Development (2007) 1.47
A role of STAT3 in Rho GTPase-regulated cell migration and proliferation. J Biol Chem (2005) 1.47
Upregulation of nestin, vimentin, and desmin in rat podocytes in response to injury. Virchows Arch (2006) 1.46
Sema3E-PlexinD1 signaling selectively suppresses disoriented angiogenesis in ischemic retinopathy in mice. J Clin Invest (2011) 1.44
c-Jun N-terminal kinases (JNK) antagonize cardiac growth through cross-talk with calcineurin-NFAT signaling. EMBO J (2003) 1.42
Rac GTPases regulate the morphology and deformability of the erythrocyte cytoskeleton. Blood (2006) 1.41
Distinct functions for Wnt/β-catenin in hair follicle stem cell proliferation and survival and interfollicular epidermal homeostasis. Cell Stem Cell (2013) 1.41
Mitochondrial DAMPs increase endothelial permeability through neutrophil dependent and independent pathways. PLoS One (2013) 1.40
The linkage disequilibrium maps of three human chromosomes across four populations reflect their demographic history and a common underlying recombination pattern. Genome Res (2005) 1.40
Oligo-astheno-teratozoospermia in mice lacking Cnot7, a regulator of retinoid X receptor beta. Nat Genet (2004) 1.40
Cell type-specific functions of Rho GTPases revealed by gene targeting in mice. Trends Cell Biol (2006) 1.39
Safety of infliximab therapy in rheumatoid arthritis patients with previous exposure to hepatitis B virus. Int J Rheum Dis (2013) 1.39
Class 5 transmembrane semaphorins control selective Mammalian retinal lamination and function. Neuron (2011) 1.39
Low doses of bromo- and iododeoxyuridine produce near-saturation labeling of adult proliferative populations in the dentate gyrus. Eur J Neurosci (2005) 1.39
Canonical Wnt signaling negatively regulates branching morphogenesis of the lung and lacrimal gland. Dev Biol (2005) 1.38
Regulation of alphaA-crystallin via Pax6, c-Maf, CREB and a broad domain of lens-specific chromatin. EMBO J (2006) 1.38
Rho GTPases in hematopoiesis and hemopathies. Blood (2009) 1.37
Rac GTPase isoforms Rac1 and Rac2 play a redundant and crucial role in T-cell development. Blood (2008) 1.37
Phosphorylation of three regulatory serines of Tob by Erk1 and Erk2 is required for Ras-mediated cell proliferation and transformation. Genes Dev (2002) 1.36
Electrochemical delamination of CVD-grown graphene film: toward the recyclable use of copper catalyst. ACS Nano (2011) 1.36
A randomized study of transendocardial injection of autologous bone marrow mononuclear cells and cell function analysis in ischemic heart failure (FOCUS-HF). Am Heart J (2011) 1.35
Polymorphisms of KDR gene are associated with coronary heart disease. J Am Coll Cardiol (2007) 1.35
A novel strategy for specifically down-regulating individual Rho GTPase activity in tumor cells. J Biol Chem (2003) 1.35
Differential interactions of FGFs with heparan sulfate control gradient formation and branching morphogenesis. Sci Signal (2009) 1.34
Increased hematopoietic stem cell mobilization in aged mice. Blood (2006) 1.34