Published in J Pathol on October 01, 2006
Evaluation of markers for CpG island methylator phenotype (CIMP) in colorectal cancer by a large population-based sample. J Mol Diagn (2007) 3.56
Molecular classification and correlates in colorectal cancer. J Mol Diagn (2007) 3.25
Molecular correlates with MGMT promoter methylation and silencing support CpG island methylator phenotype-low (CIMP-low) in colorectal cancer. Gut (2007) 1.53
V600EBraf induces gastrointestinal crypt senescence and promotes tumour progression through enhanced CpG methylation of p16INK4a. EMBO Mol Med (2010) 1.36
Oncogenes induce senescence with incomplete growth arrest and suppress the DNA damage response in immortalized cells. Aging Cell (2011) 0.99
Cyclooxygenase-2 overexpression is common in serrated and non-serrated colorectal adenoma, but uncommon in hyperplastic polyp and sessile serrated polyp/adenoma. BMC Cancer (2008) 0.93
Oncogene-triggered suppression of DNA repair leads to DNA instability in cancer. Oncotarget (2014) 0.76
A National Cancer Institute Workshop on Hereditary Nonpolyposis Colorectal Cancer Syndrome: meeting highlights and Bethesda guidelines. J Natl Cancer Inst (1997) 5.68
Analysis of mismatch repair genes in hereditary non-polyposis colorectal cancer patients. Nat Med (1996) 4.87
Chromosome 5 allele loss in human colorectal carcinomas. Nature (1987) 4.46
Genetic mapping of a locus predisposing to human colorectal cancer. Science (1993) 4.12
BRAF mutation is associated with DNA methylation in serrated polyps and cancers of the colorectum. Gut (2004) 4.06
The grading of rectal cancer: historical perspectives and a multivariate analysis of 447 cases. Histopathology (1986) 3.70
A new prognostic classification of rectal cancer. Lancet (1987) 3.56
Replication errors in benign and malignant tumors from hereditary nonpolyposis colorectal cancer patients. Cancer Res (1994) 3.25
Clinicopathological staging for colorectal cancer: an International Documentation System (IDS) and an International Comprehensive Anatomical Terminology (ICAT). J Gastroenterol Hepatol (1991) 2.83
Lymphocytic infiltration and survival in rectal cancer. J Clin Pathol (1986) 2.80
DNA microsatellite instability in hyperplastic polyps, serrated adenomas, and mixed polyps: a mild mutator pathway for colorectal cancer? J Clin Pathol (1999) 2.78
Tumour 'budding' as an index to estimate the potential of aggressiveness in rectal cancer. Histopathology (2002) 2.68
Direct mutational analysis in a family with hereditary non-polyposis colorectal cancer. Aust N Z J Med (1994) 2.68
Restorative proctocolectomy with ileal reservoir: pathological and histochemical study of mucosal biopsy specimens. J Clin Pathol (1987) 2.33
Features of colorectal cancers with high-level microsatellite instability occurring in familial and sporadic settings: parallel pathways of tumorigenesis. Am J Pathol (2001) 2.29
Role of intestinal metaplasia in the histogenesis of gastric carcinoma. J Clin Pathol (1980) 2.05
Clinical and molecular features of the hereditary mixed polyposis syndrome. Gastroenterology (1997) 1.96
Prognostic significance of extensive microsatellite instability in sporadic clinicopathological stage C colorectal cancer. Br J Surg (2000) 1.93
Methylation of O-6-methylguanine DNA methyltransferase characterizes a subset of colorectal cancer with low-level DNA microsatellite instability. Cancer Res (2001) 1.87
Dysplasia and deoxyribonucleic acid aneuploidy in the assessment of precancerous changes in chronic ulcerative colitis. Observer variation and correlations. Gastroenterology (1988) 1.81
Malignant colorectal polyps. Gastroenterology (1995) 1.80
A variant of intestinal metaplasia associated with gastric carcinoma: a histochemical study. Histopathology (1979) 1.76
Serrated route to colorectal cancer: back street or super highway? J Pathol (2001) 1.73
Promoter hypermethylation frequency and BRAF mutations distinguish hereditary non-polyposis colon cancer from sporadic MSI-H colon cancer. Fam Cancer (2004) 1.66
Paget's disease of the anus: a clinicopathological study. Br J Surg (1989) 1.60
DNA microsatellite instability and mismatch repair protein loss in adenomas presenting in hereditary non-polyposis colorectal cancer. Gut (2000) 1.58
Accumulated clonal genetic alterations in familial and sporadic colorectal carcinomas with widespread instability in microsatellite sequences. Am J Pathol (1998) 1.55
Methylation patterns define two types of hyperplastic polyp associated with colorectal cancer. Gut (2004) 1.53
Prognostic significance of the wnt signalling pathway molecules APC, beta-catenin and E-cadherin in colorectal cancer: a tissue microarray-based analysis. Histopathology (2007) 1.53
The mucin profiles of normal gastric mucosa, intestinal metaplasia and its variants and gastric carcinoma. Histochem J (1981) 1.52
Colorectal adenoma and cancer divergence. Evidence of multilineage progression. Am J Pathol (1999) 1.50
Demographic and pathological characteristics of serrated polyps of colorectum. Histopathology (2005) 1.43
Do all colorectal carcinomas arise in preexisting adenomas? World J Surg (1989) 1.43
HPP1: a transmembrane protein-encoding gene commonly methylated in colorectal polyps and cancers. Proc Natl Acad Sci U S A (2001) 1.41
Colorectal goblet cell sialomucin heterogeneity: its relation to malignant disease. J Clin Pathol (1986) 1.41
Sulphomucins and precancerous lesions of the human stomach. Histopathology (1980) 1.40
Significance of MUC1 and MUC2 mucin expression in colorectal cancer. J Clin Pathol (1996) 1.39
Prognostic factors in colonic cancer. Histopathology (1989) 1.38
Familial giant hyperplastic polyposis predisposing to colorectal cancer: a new hereditary bowel cancer syndrome. J Pathol (1996) 1.38
Neuromuscular and vascular hamartoma of the small intestine: is it Crohn's disease? Gut (1987) 1.38
Mucinous carcinoma of the rectum. Histopathology (1987) 1.38
Immunohistochemical staining patterns of MUC1, MUC2, MUC4, and MUC5AC mucins in hyperplastic polyps, serrated adenomas, and traditional adenomas of the colorectum. J Histochem Cytochem (1999) 1.36
Hereditary nonpolyposis colorectal cancer and colonic adenomas: aggressive adenomas? Semin Surg Oncol (1996) 1.33
Relation between metaplastic polyp and carcinoma of the colorectum. Lancet (1983) 1.29
Promoter methylation of the mutated in colorectal cancer gene is a frequent early event in colorectal cancer. Oncogene (2007) 1.28
DNA content and the adenoma-carcinoma sequence in the colorectum. J Clin Pathol (1986) 1.26
Extensive DNA methylation in normal colorectal mucosa in hyperplastic polyposis. Gut (2006) 1.25
A morphologic and histochemical study of metaplastic polyps of the colorectum. Cancer (1984) 1.24
Role of BRAF-V600E in the serrated pathway of colorectal tumourigenesis. J Pathol (2007) 1.24
Role of APAF-1, E-cadherin and peritumoral lymphocytic infiltration in tumour budding in colorectal cancer. J Pathol (2007) 1.22
A classification of gastric dysplasia. Histopathology (1983) 1.21
Role of RHAMM within the hierarchy of well-established prognostic factors in colorectal cancer. Gut (2008) 1.19
My approach to serrated polyps of the colorectum. J Clin Pathol (2004) 1.19
Infrequent K-ras codon 12 mutation in serrated adenomas of human colorectum. Gut (1998) 1.19
Rectal cancer risk in hereditary nonpolyposis colorectal cancer after abdominal colectomy. International Collaborative Group on HNPCC. Ann Surg (1997) 1.18
Anal cancer and human papillomaviruses. Dis Colon Rectum (1989) 1.17
Mucin histochemistry of the columnar epithelium of the oesophagus: a retrospective study. J Clin Pathol (1981) 1.15
Mucin core protein expression in colorectal cancers with high levels of microsatellite instability indicates a novel pathway of morphogenesis. Clin Cancer Res (2000) 1.15
Histological categorisation of fibrotic cancer stroma in advanced rectal cancer. Gut (2004) 1.14
Observer study of the grading of dysplasia in ulcerative colitis: comparison with clinical outcome. Hum Pathol (1989) 1.14
The reliability of immunohistochemistry as a prescreening method for the diagnosis of hereditary nonpolyposis colorectal cancer (HNPCC)--results of an international collaborative study. Fam Cancer (2001) 1.13
Value of mucin histochemistry in follow up surveillance of patients with long standing ulcerative colitis. J Clin Pathol (1986) 1.12
Epithelial misplacement in Peutz-Jeghers polyps. A diagnostic pitfall. Am J Surg Pathol (1987) 1.12
Colonic pericrypt sheath cells: characterisation of cell type with new monoclonal antibody. J Clin Pathol (1987) 1.11
Expression of Bcl-2 protein is decreased in colorectal adenocarcinomas with microsatellite instability. Oncogene (1999) 1.08
Human papillomavirus type 16 DNA in anal squamous cell carcinoma. Lancet (1987) 1.07
Adenocarcinoma of colon differentiating as dome epithelium of gut-associated lymphoid tissue. Histopathology (2000) 1.07
Oesophageal squamous cell carcinoma may develop within a background of accumulating DNA methylation in normal and dysplastic mucosa. Gut (2006) 1.07
A case of myoepithelial carcinoma displaying biallelic inactivation of the tumour suppressor gene APC in a patient with familial adenomatous polyposis. J Clin Pathol (2002) 1.06
Prognostic significance of mucins in colorectal cancer with different DNA mismatch-repair status. J Clin Pathol (2006) 1.05
Serrated adenoma and colorectal cancer. J Pathol (1999) 1.04
Value of flow cytometric determination of ploidy as a guide to prognosis in operable rectal cancer: a multivariate analysis. Int J Colorectal Dis (1987) 1.02
Low level microsatellite instability may be associated with reduced cancer specific survival in sporadic stage C colorectal carcinoma. Gut (2005) 1.02
Occult lymph node metastases detected by cytokeratin immunohistochemistry predict recurrence in "node-negative" colorectal cancer. J Gastroenterol (1997) 1.01
Immunoperoxidase staining for cytokeratins 8 and 18 is very sensitive for detection of occult node metastasis of colorectal cancer: a comparison with genetic analysis of K-ras. Histopathology (1998) 1.00
The epidemiology of endometrial cancer in hereditary nonpolyposis colorectal cancer. Anticancer Res (1994) 0.99
Immunohistochemical demonstration of IgA and secretory component in relation to epithelial cell differentiation in normal colorectal mucosa and metaplastic polyp: a semiquantitative study. Histochem J (1985) 0.98
Reciprocal relationship between the tumor suppressors p53 and BAX in primary colorectal cancers. Oncogene (1998) 0.97
Fat clearance method versus manual dissection of lymph nodes in specimens of rectal cancer. Int J Colorectal Dis (1986) 0.97
Ultrastructural localization of epithelial mucin core proteins in colorectal tissues. J Histochem Cytochem (1999) 0.97
Proximal versus distal hyperplastic polyps of the colorectum: different lesions or a biological spectrum? J Clin Pathol (2004) 0.97
Bone metastases in carcinoma of the rectum: a clinical and pathological review. Eur J Surg Oncol (1989) 0.96
Colorectal goblet cell mucins in familial adenomatous polyposis. J Clin Pathol (1987) 0.96
A prospective study of the use of 111In-labelled monoclonal antibody against carcino-embryonic antigen in colorectal cancer and of some biological factors affecting its uptake. Int J Colorectal Dis (1989) 0.95
Poorly differentiated tumours of the anal canal: a diagnostic strategy for the surgical pathologist. Histopathology (2007) 0.94
A novel classification of tumour budding in colorectal cancer based on the presence of cytoplasmic pseudo-fragments around budding foci. Histopathology (2005) 0.93
Infrequent loss of heterozygosity of APC/MCC and DCC genes in gastric cancer showing DNA microsatellite instability. J Clin Pathol (1999) 0.93
Combined analysis of VEGF and EGFR predicts complete tumour response in rectal cancer treated with preoperative radiotherapy. Br J Cancer (2008) 0.92
Chromosome 5 allele loss in familial and sporadic colorectal adenomas. Br J Cancer (1989) 0.92
Clinicopathological assessment and staging of colorectal cancer. Br J Surg (1988) 0.92
MUC1 and MUC2 mucins in flat and polypoid colorectal adenomas. J Clin Pathol (1997) 0.90
Discrepancies between East and West. Cancer (2000) 0.89
Trends in colorectal cancer incidence and histologic findings in Maori and Polynesian residents of New Zealand. Cancer (1993) 0.89
Proliferation, apoptosis, and survival in high-level microsatellite instability sporadic colorectal cancer. Clin Cancer Res (2001) 0.88
Biological significance of microsatellite instability-low (MSI-L) status in colorectal tumors. Am J Pathol (2001) 0.87
Diagnosis of hereditary non-polyposis colorectal cancer (HNPCC). Gut (2004) 0.87
Intestinal metaplasia subtypes and Helicobacter pylori infection: a comparison of ethnic groups in New Zealand. J Gastroenterol Hepatol (1998) 0.86
p73 is up-regulated in a subset of hepatocellular carcinomas. Hepatology (2000) 0.85
Classification of primary gut lymphomas. Lancet (1988) 0.85