Published in Proteins on November 01, 2006
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Crystal structure of the polymerase PA(C)-PB1(N) complex from an avian influenza H5N1 virus. Nature (2008) 3.06
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A dual function of the CRISPR-Cas system in bacterial antivirus immunity and DNA repair. Mol Microbiol (2010) 2.70
Crystal structure of the CorA Mg2+ transporter. Nature (2006) 2.64
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Structure of RapA, a Swi2/Snf2 protein that recycles RNA polymerase during transcription. Structure (2008) 1.86
Triclinic lysozyme at 0.65 A resolution. Acta Crystallogr D Biol Crystallogr (2007) 1.77
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The crystal structure of spermidine synthase with a multisubstrate adduct inhibitor. Nat Struct Biol (2002) 1.63
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Integrating structure, bioinformatics, and enzymology to discover function: BioH, a new carboxylesterase from Escherichia coli. J Biol Chem (2003) 1.61
Staphylococcus aureus IsdG and IsdI, heme-degrading enzymes with structural similarity to monooxygenases. J Biol Chem (2004) 1.58
Large-scale evaluation of protein reductive methylation for improving protein crystallization. Nat Methods (2008) 1.55
Quantum model of catalysis based on a mobile proton revealed by subatomic x-ray and neutron diffraction studies of h-aldose reductase. Proc Natl Acad Sci U S A (2008) 1.55
Contributions to the NIH-NIGMS Protein Structure Initiative from the PSI Production Centers. Structure (2008) 1.52
B. subtilis ykuD protein at 2.0 A resolution: insights into the structure and function of a novel, ubiquitous family of bacterial enzymes. Proteins (2006) 1.47
Structural plasticity in the oestrogen receptor ligand-binding domain. EMBO Rep (2007) 1.47
Time-controlled microfluidic seeding in nL-volume droplets to separate nucleation and growth stages of protein crystallization. Angew Chem Int Ed Engl (2006) 1.45
High-throughput protein purification and quality assessment for crystallization. Methods (2011) 1.44
Crystal structure of Enterococcus faecalis SlyA-like transcriptional factor. J Biol Chem (2003) 1.42
Structure- and function-based characterization of a new phosphoglycolate phosphatase from Thermoplasma acidophilum. J Biol Chem (2003) 1.41
Crystal structure of murine sCEACAM1a[1,4]: a coronavirus receptor in the CEA family. EMBO J (2002) 1.37
Methyltransferase that modifies guanine 966 of the 16 S rRNA: functional identification and tertiary structure. J Biol Chem (2006) 1.33
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Elemental isomerism: a boron-nitrogen surrogate for a carbon-carbon double bond increases the chemical diversity of estrogen receptor ligands. Chem Biol (2007) 1.31
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The crystal structure of a TL/CD8alphaalpha complex at 2.1 A resolution: implications for modulation of T cell activation and memory. Immunity (2003) 1.25
The structures of the thrombospondin-1 N-terminal domain and its complex with a synthetic pentameric heparin. Structure (2006) 1.25
Structural basis for dimerization of ICAM-1 on the cell surface. Mol Cell (2004) 1.24
Structure of the retinal determination protein Dachshund reveals a DNA binding motif. Structure (2002) 1.22
Crystal structure of Thermotoga maritima 0065, a member of the IclR transcriptional factor family. J Biol Chem (2002) 1.20
Protein surface analysis for function annotation in high-throughput structural genomics pipeline. Protein Sci (2005) 1.20
Bifidobacterium longum subsp. infantis ATCC 15697 α-fucosidases are active on fucosylated human milk oligosaccharides. Appl Environ Microbiol (2011) 1.20
Dodecamer structure of severe acute respiratory syndrome coronavirus nonstructural protein nsp10. J Virol (2006) 1.19
Structure of apo- and monometalated forms of NDM-1--a highly potent carbapenem-hydrolyzing metallo-β-lactamase. PLoS One (2011) 1.19
Structures of sortase B from Staphylococcus aureus and Bacillus anthracis reveal catalytic amino acid triad in the active site. Structure (2004) 1.18
Structural genomics: keeping up with expanding knowledge of the protein universe. Curr Opin Struct Biol (2007) 1.17
The structure and ligand binding properties of the B. subtilis YkoF gene product, a member of a novel family of thiamin/HMP-binding proteins. J Mol Biol (2004) 1.17
Biochemical and structural characterization of a novel family of cystathionine beta-synthase domain proteins fused to a Zn ribbon-like domain. J Mol Biol (2007) 1.16
Structural basis of membrane targeting by the Phox homology domain of cytokine-independent survival kinase (CISK-PX). J Biol Chem (2004) 1.16
Functional and structural characterization of four glutaminases from Escherichia coli and Bacillus subtilis. Biochemistry (2008) 1.15
Production of selenomethionine-labeled proteins in two-liter plastic bottles for structure determination. J Struct Funct Genomics (2004) 1.15
Structure of surface layer homology (SLH) domains from Bacillus anthracis surface array protein. J Biol Chem (2011) 1.12
Structural insight into the mechanism of c-di-GMP hydrolysis by EAL domain phosphodiesterases. J Mol Biol (2010) 1.12
Crystal structure of tabtoxin resistance protein complexed with acetyl coenzyme A reveals the mechanism for beta-lactam acetylation. J Mol Biol (2003) 1.12
New antiviral target revealed by the hexameric structure of mouse hepatitis virus nonstructural protein nsp15. J Virol (2006) 1.11
Structure of Escherichia coli ribose-5-phosphate isomerase: a ubiquitous enzyme of the pentose phosphate pathway and the Calvin cycle. Structure (2003) 1.11
Novel catalytic mechanism of glycoside hydrolysis based on the structure of an NAD+/Mn2+ -dependent phospho-alpha-glucosidase from Bacillus subtilis. Structure (2004) 1.11
Protein functional surfaces: global shape matching and local spatial alignments of ligand binding sites. BMC Struct Biol (2008) 1.09
Optimization of benzoxazole-based inhibitors of Cryptosporidium parvum inosine 5'-monophosphate dehydrogenase. J Med Chem (2013) 1.09
Activation of inhibitors by sortase triggers irreversible modification of the active site. J Biol Chem (2007) 1.09
A conformational switch controls cell wall-remodelling enzymes required for bacterial cell division. Mol Microbiol (2012) 1.08
C-banded karyotypes of two Silene species with heteromorphic sex chromosomes. Genome (2002) 1.07
Capsule anchoring in Bacillus anthracis occurs by a transpeptidation reaction that is inhibited by capsidin. Mol Microbiol (2008) 1.06
Structural and functional analysis of AsbF: origin of the stealth 3,4-dihydroxybenzoic acid subunit for petrobactin biosynthesis. Proc Natl Acad Sci U S A (2008) 1.06
Extracytoplasmic PAS-like domains are common in signal transduction proteins. J Bacteriol (2009) 1.05
Crystal structure of secretory protein Hcp3 from Pseudomonas aeruginosa. J Struct Funct Genomics (2011) 1.05
Deep trefoil knot implicated in RNA binding found in an archaebacterial protein. Proteins (2003) 1.05
Target selection and determination of function in structural genomics. IUBMB Life (2003) 1.05
Predicting protein crystallization propensity from protein sequence. J Struct Funct Genomics (2010) 1.04
Harvesting the high-hanging fruit: the structure of the YdeN gene product from Bacillus subtilis at 1.8 angstroms resolution. Acta Crystallogr D Biol Crystallogr (2004) 1.04
Structural basis and catalytic mechanism for the dual functional endo-beta-N-acetylglucosaminidase A. PLoS One (2009) 1.04
Crystal structure of a novel shikimate dehydrogenase from Haemophilus influenzae. J Biol Chem (2005) 1.03
NDM-1, the ultimate promiscuous enzyme: substrate recognition and catalytic mechanism. FASEB J (2013) 1.02
Structural basis for catalysis by the mono- and dimetalated forms of the dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase. J Mol Biol (2010) 1.02
Characterization of a Bacillus subtilis transporter for petrobactin, an anthrax stealth siderophore. Proc Natl Acad Sci U S A (2009) 1.01
The membrane-associated lipoprotein-9 GmpC from Staphylococcus aureus binds the dipeptide GlyMet via side chain interactions. Biochemistry (2004) 1.01
Structure-guided optimization of estrogen receptor binding affinity and antagonist potency of pyrazolopyrimidines with basic side chains. J Med Chem (2007) 1.01
Structural and biochemical characterization of the type II fructose-1,6-bisphosphatase GlpX from Escherichia coli. J Biol Chem (2008) 1.00
Heparin-induced cis- and trans-dimerization modes of the thrombospondin-1 N-terminal domain. J Biol Chem (2007) 1.00
The 2.2 A resolution structure of RpiB/AlsB from Escherichia coli illustrates a new approach to the ribose-5-phosphate isomerase reaction. J Mol Biol (2003) 1.00
The crystal structure of Escherichia coli MoaB suggests a probable role in molybdenum cofactor synthesis. J Biol Chem (2004) 1.00
Structures of open (R) and close (T) states of prephenate dehydratase (PDT)--implication of allosteric regulation by L-phenylalanine. J Struct Biol (2007) 0.99